Abstract:
:Certain vertebrates are capable of regenerating parts of the eye, including the lens. Depending on the species, two principal forms of in vivo lens regeneration have been described wherein the new lens arises from either the pigmented epithelium of the dorsal iris or the cornea epithelium. These forms of lens regeneration are triggered by retinal factors present in the eye. Studies have begun to illuminate the nature of the signals that support lens regeneration. This review describes evidence for the involvement of specific signaling pathways in lens regeneration, including the FGF, retinoic acid, TGF-beta, Wnt, and Hedgehog pathways.
journal_name
Curr Top Microbiol Immunoljournal_title
Current topics in microbiology and immunologyauthors
Henry JJ,Thomas AG,Hamilton PW,Moore L,Perry KJdoi
10.1007/82_2012_289subject
Has Abstractpub_date
2013-01-01 00:00:00pages
75-98eissn
0070-217Xissn
2196-9965journal_volume
367pub_type
杂志文章,评审abstract::Host cell attachment by influenza A viruses is mediated by the hemagglutinin glycoprotein (HA), and the recognition of specific types of sialic acid -containing glycan receptors constitutes one of the major determinants of viral host range and transmission properties. Structural studies have elucidated some of the vir...
journal_title:Current topics in microbiology and immunology
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journal_title:Current topics in microbiology and immunology
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journal_title:Current topics in microbiology and immunology
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journal_title:Current topics in microbiology and immunology
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journal_title:Current topics in microbiology and immunology
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