Abstract:
:Headspace solid phase microextraction (HSSPME) of chemically generated selenium hydride from alkaline solution followed by thermal desorption (TD) coupled directly to a microwave plasma (MWP) source has been examined for the optical emission spectrometric (OES) determination of Se. Various chemical and operating parameters including the NaBH(4) and HCl concentrations as well as the fiber exposure time and desorption temperature have been optimized. Alternatively, continuous hydride generation (HG) from alkaline medium and inductively coupled plasma (ICP) may be used for Se determination by OES. With the procedure developed, the determination of Se in dietary supplements at the tens of μgg(-1) level and an accuracy of 3-6% could be performed even in the presence of the 1000-fold excess of Fe and Cu. Additionally, Se was determined in the NIST 8418 material (Wheat gluten) with a certified concentration of Se of 2.58 ± 0.19 μgg(-1), and a value of 2.45 ± 0.25 μgg(-1) was found using HG-HSSPME-MWP-OES. The detection limit for Se (3.2 ng ml(-1)) with the proposed procedure was comparable to those obtained with HG-ICP-OES and the calibration curve was linear of about 2 orders of magnitude.
journal_name
J Pharm Biomed Analjournal_title
Journal of pharmaceutical and biomedical analysisauthors
Tyburska A,Jankowski Kdoi
10.1016/j.jpba.2012.11.011subject
Has Abstractpub_date
2013-02-23 00:00:00pages
268-72eissn
0731-7085issn
1873-264Xpii
S0731-7085(12)00616-4journal_volume
74pub_type
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