Velocity profiles in the human ductus venosus: a numerical fluid structure interaction study.

abstract：:The two main load bearing tissues of the intervertebral disc are the nucleus pulposus and the annulus fibrosus. Both tissues are composed of the same basic components, but differ in their organization and relative amounts. With degeneration, the clear distinction between the two tissues disappears. The changes in bioc...

journal_title：Biomechanics and modeling in mechanobiology

authors： van Rijsbergen MM,Barthelemy VM,Vrancken AC,Crijns SP,Wilke HJ,Wilson W,van Rietbergen B,Ito K

更新日期：2017-04-01 00:00:00

abstract：:Nanomechanics of individual collagen fibrils govern the mechanical behavior of the majority of connective tissues, yet the current models lack significant details. Majority of the current models assume a rod-shape molecule with homogenous mechanical properties. Recent X-ray crystallography revealed significantly diffe...

journal_title：Biomechanics and modeling in mechanobiology

authors： Zhou Z,Minary-Jolandan M,Qian D

更新日期：2015-06-01 00:00:00

abstract：:Articular cartilage is a multicomponent, poroviscoelastic tissue with nonlinear mechanical properties vital to its function. A consequent goal of repair or replacement of injured cartilage is to achieve mechanical properties in the repair tissue similar to healthy native cartilage. Since fresh healthy human articular ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Ronken S,Arnold MP,Ardura García H,Jeger A,Daniels AU,Wirz D

更新日期：2012-05-01 00:00:00

abstract：:Skin expansion delivers newly grown skin that maintains histological and mechanical features of the original tissue. Although it is the gold standard for cutaneous defect correction today, the underlying mechanisms remain poorly understood. Here we present a novel technique to quantify anisotropic prestrain, deformati...

journal_title：Biomechanics and modeling in mechanobiology

authors： Buganza Tepole A,Gart M,Purnell CA,Gosain AK,Kuhl E

更新日期：2015-10-01 00:00:00

abstract：:The equilibrium shapes of lipid vesicles are perturbed by rigid inclusions. In a two-dimensional vesicle, that may also model a cylindrically elongated tubule, the shape modifications can be determined analytically, and turn out to be significant even far from the inclusion. On the contrary, previous numerical work ha...

journal_title：Biomechanics and modeling in mechanobiology

authors： Biscari P,Napoli G

更新日期：2007-09-01 00:00:00

abstract：:This paper presents a differential model of the corneal transport system capable of modelling thickness changes in response to osmotic perturbations applied to either limiting membrane. The work is directed towards understanding corneal behaviour in vivo. The model considers the coupled viscous flows within the cornea...

journal_title：Biomechanics and modeling in mechanobiology

authors： Li LY,Tighe BJ,Ruberti JW

更新日期：2004-11-01 00:00:00

abstract：:The present study addresses the effect of muscle activation contributions to mitral valve leaflet response during systole. State-of-art passive hyperelastic material modeling is employed in combination with a simple active stress part. Fiber families are assumed in the leaflets: one defined by the collagen and one def...

journal_title：Biomechanics and modeling in mechanobiology

authors： Skallerud B,Prot V,Nordrum IS

更新日期：2011-02-01 00:00:00

abstract：:A predictive Lagrangian-Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and mo...

journal_title：Biomechanics and modeling in mechanobiology

authors： Weaver AA,Stitzel SM,Stitzel JD

更新日期：2017-04-01 00:00:00

abstract：:The mechanotransduction of adipocytes is not well characterized in the literature. In this study, we employ stochastic modeling fitted to experiments for characterizing the influence of mechanical stretching delivered to adipocyte monolayers on the probabilities of commitment to the adipocyte lineage, mitosis, and gro...

journal_title：Biomechanics and modeling in mechanobiology

authors： Shoham N,Gefen A

更新日期：2012-09-01 00:00:00

abstract：:The basic aim of the present contribution is the qualitative simulation of healing phenomena typically encountered in hard and soft tissue mechanics. The mechanical framework is provided by the theory of open system thermodynamics, which will be formulated in the spatial as well as in the material motion context. Whil...

journal_title：Biomechanics and modeling in mechanobiology

authors： Kuhl E,Steinmann P

更新日期：2004-06-01 00:00:00

abstract：:Past research into brain injury biomechanics has focussed on short duration impulsive events as opposed to the oscillatory loadings associated with Shaken Baby Syndrome (SBS). A series of 2D finite element models of an axial slice of the infant head were created to provide qualitative information on the behaviour of t...

journal_title：Biomechanics and modeling in mechanobiology

authors： Couper Z,Albermani F

更新日期：2008-04-01 00:00:00

abstract：:There is a growing interest in the development of patient-specific finite element models of the human lumbar spine for both the assessment of injury risk and the development of treatment strategies. A current challenge in implementing these models is that the outer annulus fibrosus of the disc is composed of concentri...

journal_title：Biomechanics and modeling in mechanobiology

authors： Michalek AJ

更新日期：2019-10-01 00:00:00

abstract：:The influence of an aortic aneurysm on blood flow waveforms is well established, but how to exploit this link for diagnostic purposes still remains challenging. This work uses a combination of experimental and computational modelling to study how aneurysms of various size affect the waveforms. Experimental studies are...

journal_title：Biomechanics and modeling in mechanobiology

authors： Sazonov I,Khir AW,Hacham WS,Boileau E,Carson JM,van Loon R,Ferguson C,Nithiarasu P

更新日期：2017-08-01 00:00:00

abstract：:It is believed that non-mammals have poor hearing at high frequencies because the sound-conduction performance of their single-ossicle middle ears declines above a certain frequency. To better understand this behavior, a dynamic three-dimensional finite-element model of the chicken middle ear was constructed. The effe...

journal_title：Biomechanics and modeling in mechanobiology

authors： Muyshondt PGG,Dirckx JJJ

更新日期：2020-02-01 00:00:00

abstract：:The compliance of the proximal aortic wall is a major determinant of cardiac afterload. Aortic compliance is often estimated based on cross-sectional area changes over the pulse pressure, under the assumption of a negligible longitudinal stretch during the pulse. However, the proximal aorta is subjected to significant...

journal_title：Biomechanics and modeling in mechanobiology

authors： Pagoulatou SZ,Ferraro M,Trachet B,Bikia V,Rovas G,Crowe LA,Vallée JP,Adamopoulos D,Stergiopulos N

更新日期：2020-07-31 00:00:00

abstract：:A dynamic model is proposed for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The dynamic behavior of the ATP/ADP concentration at the endothelial surface by viscous shear flow is investigated through simulation studies based on the dynamic ATP release model. The numerical res...

journal_title：Biomechanics and modeling in mechanobiology

authors： Qin KR,Xiang C,Xu Z,Cao LL,Ge SS,Jiang ZL

更新日期：2008-10-01 00:00:00

abstract：:The key parameters determining the elastic properties of an unidirectional mineralized bone fibril-array decomposed in two further hierarchical levels are investigated using mean field methods. Modeling of the elastic properties of mineralized micro- and nanostructures requires accurate information about the underlyin...

journal_title：Biomechanics and modeling in mechanobiology

authors： Reisinger AG,Pahr DH,Zysset PK

更新日期：2010-10-01 00:00:00

abstract：:The reopening of fluid-occluded pulmonary airways generates microbubble flows which impart complex hydrodynamic stresses to the epithelial cells lining airway walls. In this study we used boundary element solutions and finite element techniques to investigate how cell rheology influences the deformation and injury of ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Dailey HL,Ghadiali SN

更新日期：2010-06-01 00:00:00

abstract：:As a degenerative and inflammatory desease of elderly patients, about 80% of abdominal aortic aneurysms (AAA) show considerable wall calcification. Effect of calcifications on computational wall stress analyses of AAAs has been rarely treated in literature so far. Calcifications are heterogeneously distributed, non-fi...

journal_title：Biomechanics and modeling in mechanobiology

authors： Maier A,Gee MW,Reeps C,Eckstein HH,Wall WA

更新日期：2010-10-01 00:00:00

abstract：:The present study aims at investigating biomechanical failure behaviour of human aneurismal aortic tissues so as to diagnose the rupture risk of aneurysms more accurately. An inflation test is performed on aneurismal aortic tissues up to failure and full-field measurements are achieved using stereo digital image corre...

journal_title：Biomechanics and modeling in mechanobiology

authors： Kim JH,Avril S,Duprey A,Favre JP

更新日期：2012-07-01 00:00:00

abstract：:Thrombosis is a major concern in blood-coated medical devices. Contact activation, which is the initial part of the coagulation cascade in device-related thrombosis, is not considered in current thrombus formation models. In the present study, pro-coagulant reactions including the contact activation system are coupled...

journal_title：Biomechanics and modeling in mechanobiology

authors： Méndez Rojano R,Mendez S,Nicoud F

更新日期：2018-06-01 00:00:00

abstract：:Computational models of the heart have reached a level of maturity that enables sophisticated patient-specific simulations and hold potential for important applications in diagnosis and therapy planning. However, such clinical use puts strict demands on the reliability and accuracy of the models and requires the sensi...

journal_title：Biomechanics and modeling in mechanobiology

authors： Campos JO,Sundnes J,Dos Santos RW,Rocha BM

更新日期：2019-10-01 00:00:00

abstract：:Bone tissue regeneration using scaffolds is receiving an increasing interest in orthopedic surgery and tissue engineering applications. In this study, we present the geometrical characterization of a specific family of scaffolds based on a face cubic centered (FCC) arrangement of empty pores leading to analytical form...

journal_title：Biomechanics and modeling in mechanobiology

authors： Sanz-Herrera JA,Garcia-Aznar JM,Doblare M

更新日期：2008-10-01 00:00:00

abstract：:Pelvic floor dysfunction and pelvic organ prolapse have been associated with damage to the levator ani (LA) muscle, but the exact mechanisms linking them remain unknown. It has been postulated that factors such as vaginal birth and ageing may contribute to long-term, irreversible LA muscle damage. To investigate the b...

journal_title：Biomechanics and modeling in mechanobiology

authors： Li X,Kruger JA,Nash MP,Nielsen PM

更新日期：2011-07-01 00:00:00

abstract：:Growth and remodeling in the heart is driven by a combination of mechanical and hormonal signals that produce different patterns of growth in response to exercise, pregnancy, and various pathologies. In particular, increases in afterload lead to concentric hypertrophy, a thickening of the walls that increases the cont...

journal_title：Biomechanics and modeling in mechanobiology

authors： Estrada AC,Yoshida K,Saucerman JJ,Holmes JW

更新日期：2020-09-24 00:00:00

abstract：:Mineralized collagen fibrils have been usually analyzed like a two-phase composite material where crystals are considered as platelets that constitute the reinforcement phase. Different models have been used to describe the elastic behavior of the material. In this work, it is shown that when Halpin-Tsai equations are...

journal_title：Biomechanics and modeling in mechanobiology

authors： Vercher A,Giner E,Arango C,Tarancón JE,Fuenmayor FJ

更新日期：2014-04-01 00:00:00

abstract：:In contrast to most mechanical properties of the red cell, experimental information on stress relaxation (SR) of the membrane skeleton is scarce. On the other hand, many postulates or assumptions as to the value of the characteristic time of SR [Formula: see text] can be found in the literature. Here, an experiment is...

journal_title：Biomechanics and modeling in mechanobiology

authors： Fischer TM

更新日期：2017-02-01 00:00:00

abstract：:A systematic correlation between finite element models (FEMs) and histopathology is needed to define deformation thresholds associated with traumatic brain injury (TBI). In this study, a FEM of a transected piglet brain was used to reverse engineer the range of optimal shear moduli for infant (5 days old, 553-658 Pa) ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Sullivan S,Eucker SA,Gabrieli D,Bradfield C,Coats B,Maltese MR,Lee J,Smith C,Margulies SS

更新日期：2015-08-01 00:00:00

abstract：:In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous m...

journal_title：Biomechanics and modeling in mechanobiology

authors： Coccarelli A,Prakash A,Nithiarasu P

更新日期：2019-08-01 00:00:00

abstract：:Medical studies have consistently shown that the best defense against cancer is early detection. Due to this, many efforts have been made to develop methods of screening patient blood quickly and cheaply. These methods range from separation via differences in size, electrostatic potential, chemical potential, antibody...

journal_title：Biomechanics and modeling in mechanobiology

authors： Becton M,Averett RD,Wang X

更新日期：2019-04-01 00:00:00