FK506 and nerve regeneration: past, present, and future.

abstract：:Controversy surrounds the question whether free flaps remain dependent for blood supply on their vascular pedicle or if there is an autonomization by neovascularization from the surrounding wound bed. This becomes important when flap shaping or repositioning are performed. Our study involved 23 patients who received a...

journal_title：Journal of reconstructive microsurgery

authors： Heitland AS,Markowicz MP,Koellensperger E,Schoth F,Pallua N

更新日期：2009-02-01 00:00:00

abstract：:Closure of massive soft-tissue defects in patients undergoing forequarter amputation for shoulder-girdle tumors may present a daunting challenge. This report describes two patients whose forequarter amputations were closed using ipsilateral, lymphedematous, circumferential forearm fasciocutaneous free flaps. ...

journal_title：Journal of reconstructive microsurgery

authors： Zachary LS,Gottlieb LJ,Simon M,Ferguson MK,Calkins E

更新日期：1993-03-01 00:00:00

abstract：:This study was designed to quantify the relative contribution of the inferior and superior epigastric systems to infraumbilical TRAM flap skin blood flow, using laser Doppler flowmetry. In twelve flaps (11 patients), blood-flow measurements were obtained during routine elevation of the TRAM flap for breast reconstruct...

journal_title：Journal of reconstructive microsurgery

authors： Hendricks DL,Wilkens TH,Witt PD

更新日期：1994-07-01 00:00:00

abstract：:Vascularized bone allografts (VBAs) could be useful adjuncts to the clinical reconstructive surgeon's arsenal. These grafts are known experimentally to be subject to host rejection. One way to control the rejection problem would be to develop specific immune unresponsiveness via host conditioning. Using a proven relia...

journal_title：Journal of reconstructive microsurgery

authors： Paskert JP,Yaremchuk MJ,Randolph MA,Weiland AJ

更新日期：1987-04-01 00:00:00

abstract：:This study investigated the intact nerve bridge technique for overcoming peripheral nerve gap defects in a rabbit model. To create the intact nerve bridge, a 1-cm segment of the peroneal nerve is resected leaving a gap defect. The proximal and distal peroneal nerve stumps are sutured 1 cm apart, in an end-to-side fash...

journal_title：Journal of reconstructive microsurgery

authors： McCallister WV,McCallister EL,Trumble SA,Trumble TE

更新日期：2005-04-01 00:00:00

abstract：:Microvascular clamps have several potential shortcomings, including the risk of vessel injury. LeGoo, a novel reverse thermosensitive polymer (Pluromed Inc., Woburn, MA), is investigated as a substitute to vascular clamping in a microsurgical model and the technical details are described. Femoral vessels of Sprague Da...

journal_title：Journal of reconstructive microsurgery

authors： Manchio JV,Litchfield CR,Zeheb R,Bryan DJ

更新日期：2009-01-01 00:00:00

abstract：:Free jejunum was transferred to a patient with recurrent hypopharyngeal carcinoma under unfavorable cervical conditions, caused by prior therapeutic chemoradiotherapy for hypopharyngeal carcinoma and gastric pull-up with cervical leak, resulting from treatment for thoracic esophageal cancer. The cervical recipient ves...

journal_title：Journal of reconstructive microsurgery

authors： Numajiri T,Fujiwara T,Nishino K,Sowa Y,Uenaka M,Masuda S,Fujiwara H,Nakai S,Hisa Y

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND: The anterolateral region of the thigh is one of the most used donor areas for flaps. However, there are cases in which large defects require more than the conventional skin island provided by the anterolateral thigh flap (ALT). For an extended skin island flap, we developed a new boomerang thigh flap (BTF),...

journal_title：Journal of reconstructive microsurgery

authors： Barreiro GC,Fioravanti AB,Borges LHS,Snider CC

更新日期：2018-10-01 00:00:00

abstract：:A continuous epidural bupivacaine infusion was used for anesthesia in 20 patients who underwent lower extremity free tissue transfer. In 60 percent of the patients, general anesthesia supplementation with nitrous oxide was used for comfort during prolonged lying on the operating table. In all cases, this technique pro...

journal_title：Journal of reconstructive microsurgery

authors： Strecker WB,Wood MB,Wedel DJ

更新日期：1988-07-01 00:00:00

abstract：:In a comparative study, it was demonstrated that sutureless, laser-welded, end-to-end anastomoses in the rat femoral artery and vein are feasible, using either CO2 or Nd:YAG laser. Conventional microsurgical suture anastomoses served as the controls. Patency rates in experimental animals and controls were equal (96 to...

journal_title：Journal of reconstructive microsurgery

authors： Bürger RA,Gerharz CD,Draws J,Engelmann UH,Hohenfellner R

更新日期：1993-05-01 00:00:00

abstract：:Eleven patients with paralysis of muscle groups in the upper or lower extremity were clinically diagnosed after previous proximal direct trauma to the corresponding peripheral nerves, without complete nerve disruption. Patients were seen within an average of 8 months after trauma (minimum 3 months and maximum 2 years ...

journal_title：Journal of reconstructive microsurgery

authors： Nassif T,Steiger E

更新日期：1999-04-01 00:00:00

abstract：:From August 1996 to June 2000, 33 free thoracoumbilical flaps were transferred to reconstruct a variety of soft-tissue defects. The size of the flaps ranged from 10 to 40 cm in length and 8 to 25 cm in width. The blood supply to the skin island came from the largest periumbilical perforator of the deep inferior epigas...

journal_title：Journal of reconstructive microsurgery

authors： Zhang XQ,Wang SD,Fan QY,Mao BA,Zhou Y,Zhang MH

更新日期：2004-02-01 00:00:00

abstract：:The purpose of this investigation was to evaluate the ability of a specific growth factor combination, nerve growth factor (NGF) and ciliary neurotrophic factor (CNTF), to enhance peripheral nerve regeneration. Eight groups of eight Sprague-Dawley rats underwent repair of a nerve gap defect: Group A (immediate repair)...

journal_title：Journal of reconstructive microsurgery

authors： McCallister WV,McCallister EL,Dubois B,Trumble TE

更新日期：2004-08-01 00:00:00

abstract：:The use of growth factors in inducing angiogenesis and enhancing flap viability has provided promising results. Targeted gene therapy has evolved in hopes of increasing the longevity and effectiveness of these growth factor treatments. The purpose of this study was to examine the effect of preoperative treatment by va...

journal_title：Journal of reconstructive microsurgery

authors： Zhang F,Yang F,Hu EC,Sones W,Lei M,Lineaweaver WC

更新日期：2005-08-01 00:00:00

abstract：:To assist nascent microsurgeons in the initial practices of handling instruments and tying knots before using an animal model, the authors discuss surgical gauze, which will be of benefit to all trainees. In this model, the nascent microsurgeon can familiarize himself or herself with the operating microscope, correct ...

journal_title：Journal of reconstructive microsurgery

authors： Demirseren ME,Tosa Y,Hosaka Y

更新日期：2003-08-01 00:00:00

abstract：:Free flaps are usually needed for the reconstruction of extensive facial burns, but the final result is often a poor texture and color match. The authors report a burn case managed with a radial forearm free flap. The aesthetic result was improved by surgical tattooing of the flap, including the appearance of a beard....

journal_title：Journal of reconstructive microsurgery

authors： Coessens B,Van Geertruyden J,De Mey A

更新日期：1993-09-01 00:00:00

abstract：:Traumatic damage to the common peroneal nerve due to sharp injury, gunshot wound, sciatic nerve tumor, radiculopathy, or hip replacement surgery may result in foot drop. We present an alternative strategy for reanimation of foot drop following deep peroneal nerve palsy, successfully restoring voluntary movement. Fourt...

journal_title：Journal of reconstructive microsurgery

authors： Nath RK,Lyons AB,Paizi M

更新日期：2008-08-01 00:00:00

abstract：:Phyllodes tumors (PTs) are uncommon fibroepithelial tumors of the breast, noteworthy for their difficult excisions and high recurrence rates. In the setting of recurrence, there is no consensus in the literature as to the extent of excision or the impact on reconstructive options. Breast-conserving surgery and simple ...

journal_title：Journal of reconstructive microsurgery

authors： Atalla MA,Rozen WM,Grinsell D,Hyett A,Prakash S,Cham A

更新日期：2011-05-01 00:00:00

abstract：:Apolipoprotein E (apo E) is thought to mediate the reutilization of myelin cholesterol for nerve regeneration. Prior research suggests that apo E is not essential for nerve regeneration following a nerve crush injury. This study was conducted to determine if apo E is essential for nerve regeneration after nerve transe...

journal_title：Journal of reconstructive microsurgery

authors： Genden EM,Watanabe O,Mackinnon SE,Hunter DA,Strasberg SR

更新日期：2002-08-01 00:00:00

abstract：:When faced with venous insufficiency following replantation or free-tissue transfer, the surgeons' first choice is surgical repair. When repair is not possible, medicinal leeches may be applied to relieve congestion. However, leeches increase the possibility of infection through their gut contents, and there are times...

journal_title：Journal of reconstructive microsurgery

authors： Smoot EC,Ruiz-Inchaustegui JA,Roth AC

更新日期：1995-01-01 00:00:00

abstract：:Shoulder pathology and its diagnosis must be considered in evaluation of the patient suspected of having thoracic outlet syndrome (TOS). Overlooking usually treatable conditions in the shoulder may lead to unfavorable results, if treatment is directed, instead, to neurolysis of the brachial plexus or first rib resecti...

journal_title：Journal of reconstructive microsurgery

authors： Levin LS,Dellon AL

更新日期：1992-07-01 00:00:00

abstract：:Posttraumatic infected massive bone defects in lower extremities are difficult to repair because they frequently exhibit massive bone and/or soft tissue defects, serious bone infection, and excessive scar proliferation. This study aimed to determine whether these defects could be classified and repaired at a single st...

journal_title：Journal of reconstructive microsurgery

authors： Yang YF,Xu ZH,Zhang GM,Wang JW,Hu SW,Hou ZQ,Xu DC

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:This is a systematic review for evaluating the evidence for functional outcomes after decellularized nerve use in clinical setting. Decellularized nerves are allografts whose antigenic components have been removed, leaving only a scaffold that promotes the full regeneration of axons. METHODS:Literature rese...

journal_title：Journal of reconstructive microsurgery

authors： Deslivia MF,Lee HJ,Adikrishna A,Jeon IH

更新日期：2015-11-01 00:00:00

abstract：:Conversion of the straight fibula bone flap into the parabolic mandible shape can be performed using customized acrylic templates made from a 1:1 mandible computed tomography scan and lateral cephalogram. The premise of the current study is to objectively quantify the variability in a series of acrylic templates used ...

journal_title：Journal of reconstructive microsurgery

authors： Matros E,Santamaria E,Cordeiro PG

更新日期：2013-11-01 00:00:00

abstract：:Facial paralysis (FP) remains today one of the most disturbing cranial nerve disorders. The present study utilized the rat model of FP and examined a dual approach of combining the current microsurgical treatment of cross-facial nerve graft (CFNG) with local administration of insulin-like growth factor-I (IGF-I). The ...

journal_title：Journal of reconstructive microsurgery

authors： Thanos PK,Tiangco DA,Terzis JK

更新日期：2001-07-01 00:00:00

abstract：:The etiopathology, clinical features, and treatment of carpal tunnel syndrome (CTS) in long-term hemodialyzed patients, are discussed in the light of new clinical findings. Conclusions summarizing the specific characteristics of CTS in hemodialyzed patients include the following. 1) There is a relatively equal sex rat...

journal_title：Journal of reconstructive microsurgery

authors： Corradi M,Paganelli E,Pavesi G

更新日期：1989-04-01 00:00:00

abstract：:The goal of craniofacial reconstruction is not only life-saving but also facial aesthetics. From this viewpoint the authors evaluated the facial symmetry of patients after craniofacial reconstruction. The subjects were seven patients reconstructed after craniofacial resections. Their CT or MR images were evaluated jus...

journal_title：Journal of reconstructive microsurgery

authors： Sarukawa S,Okazaki M,Asato H,Koshima I

更新日期：2006-10-01 00:00:00

abstract：:The authors treated 14 patients (13 men and one woman), using a sensate radial forearm flap. Their ages at operation ranged from 27 to 67 years (mean: 52 years). Preoperative conditions were amputations in 10 cases, degloving injury in three, and crush injury in one. Reconstructive sites involved the thumb in nine cas...

journal_title：Journal of reconstructive microsurgery

authors： Yamauchi T,Yajima H,Kizaki K,Kobata Y,Fukui A,Tamai S

更新日期：2000-11-01 00:00:00

abstract：:Nerve transection using rat sciatic nerves was employed to observe morphologic changes in the periodic denervation of Pacinian corpuscles. During periods of from 1 to 20 weeks after surgery, a total of 15 corpuscles were obtained under the operating microscope and processed for morphologic analysis using light and ele...

journal_title：Journal of reconstructive microsurgery

authors： Koshima I,Moriguchi T

更新日期：1999-05-01 00:00:00

abstract：:Small fiber pathology is a common clinical entity with a variable clinical presentation and etiology. Unfortunately, little has been described regarding its treatment because a majority of cases are idiopathic. Hence, treatment often consists of symptomatic management of pain and autonomic dysfunction. This report des...

journal_title：Journal of reconstructive microsurgery

authors： Peled ZM

更新日期：2013-10-01 00:00:00