The processing of ultrafine-grained Mg tubes for biodegradable stents.

Abstract:

:An investigation was carried out on equal-channel angular pressing (ECAP) and extrusion processing of a ZM21 Mg alloy to obtain an improved candidate material for the manufacturing of biodegradable Mg stents. Ultrafine-grain size billets of the ZM21 alloy were obtained by two-stage ECAP aimed at achieving an initial refining of the structure at 200°C and then reaching the submicrometer grain size range by lowering the processing temperature down to 150°C. The investigation revealed a significant improvement in the properties of the ECAP-treated samples compared with the starting coarse-grained ZM21 alloy. The 0.2% yield strength rose from 180 to 340 MPa after 150°C ECAP processing, while maintaining a fairly high tensile ductility. The ultrafine ZM21 alloy billets were then used for the extrusion of stent precursors having the form of small-size tubes. The grain size after extrusion remained in the submicrometer range while the hardness was revealed to be significantly higher than that of the coarse-grained ZM21 Mg alloy. It was demonstrated that processing of biodegradable Mg stent having an ultrafine-grained microstructure by ECAP and low-temperature extrusion is feasible and that the obtained products feature promising properties.

journal_name

Acta Biomater

journal_title

Acta biomaterialia

authors

Ge Q,Dellasega D,Demir AG,Vedani M

doi

10.1016/j.actbio.2013.01.010

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

8604-10

issue

10

eissn

1742-7061

issn

1878-7568

pii

S1742-7061(13)00013-5

journal_volume

9

pub_type

杂志文章
  • Characterization of the mechanical properties of tough biopolymer fibres from the mussel byssus of Aulacomya ater.

    abstract::Byssus fibres are tough biopolymer fibres produced by mussels to attach themselves to rocks. In this communication, we present the mechanical properties of the byssus from the South American mussel Aulacomya ater which have not been previously reported in the literature. The mechanical properties of the whole threads ...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2008.01.014

    authors: Troncoso OP,Torres FG,Grande CJ

    更新日期:2008-07-01 00:00:00

  • Regulation of chitosan-mediated differentiation of human olfactory receptor neurons by insulin-like growth factor binding protein-2.

    abstract::Olfaction is normally taken for granted in our lives, not only assisting us to escape from dangers, but also increasing our quality of life. Although olfactory neuroepithelium (ON) can reconstitute its olfactory receptor neurons (ORNs) after injury, no adequate treatment for olfactory loss has yet emerged. The present...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2019.08.022

    authors: Huang TW,Li ST,Wang YH,Young TH

    更新日期:2019-10-01 00:00:00

  • Fibrin glue mesh fixation combined with mesenchymal stem cells or exosomes modulates the inflammatory reaction in a murine model of incisional hernia.

    abstract::Surgical meshes are effective and frequently used to reinforce soft tissues. Fibrin glue (FG) has been widely used for mesh fixation and is also considered an optimal vehicle for stem cell delivery. The aim of this preclinical study was to evaluate the therapeutic effect of MSCs and their exosomes combined with FG for...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2018.02.014

    authors: Blázquez R,Sánchez-Margallo FM,Álvarez V,Usón A,Marinaro F,Casado JG

    更新日期:2018-04-15 00:00:00

  • Superhydrophobic effect on the adsorption of human serum albumin.

    abstract::Analytical protocol greatly influences the measurement of human serum albumin (HSA) adsorption to commercial expanded polytetrafluororethylene (ePTFE) exhibiting superhydrophobic wetting properties. Degassing of buffer solutions and evacuation of ePTFE adsorbent to remove trapped air immediately prior to contact with ...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2008.11.003

    authors: Leibner ES,Barnthip N,Chen W,Baumrucker CR,Badding JV,Pishko M,Vogler EA

    更新日期:2009-06-01 00:00:00

  • Peptide-mediated shape- and size-tunable synthesis of gold nanostructures.

    abstract::While several biological processes have been shown to be useful for the production of well-designed, inorganic nanostructures, the mechanism(s) controlling the size and shape of nano and micron size particles remains elusive. Here we report on the controlled size- and shape-specific production of gold nanostructures u...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2010.01.019

    authors: Kim J,Rheem Y,Yoo B,Chong Y,Bozhilov KN,Kim D,Sadowsky MJ,Hur HG,Myung NV

    更新日期:2010-07-01 00:00:00

  • Modified bacterial outer membrane vesicles induce autoantibodies for tumor therapy.

    abstract::Using monoclonal antibodies to block tumor angiogenesis has yielded effective antitumor effects. However, this treatment method has long cycles and is very expensive; therefore, its long-term and extensive application is limited. In this study, we developed a nanovaccine using bacterial biomembranes as carriers for an...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2020.03.030

    authors: Huang W,Shu C,Hua L,Zhao Y,Xie H,Qi J,Gao F,Gao R,Chen Y,Zhang Q,Li W,Yuan M,Ye C,Ma Y

    更新日期:2020-05-01 00:00:00

  • Processing and biocompatibility evaluation of laser processed porous titanium.

    abstract::The Laser Engineered Net Shaping (LENS) method was used to fabricate porous Ti implants. Porous Ti structures with controlled porosity in the range of 17-58 vol.% and pore size up to 800 microm were produced by controlling LENS parameters, which showed a broad range of mechanical strength of 24-463 MPa and a low Young...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2007.05.009

    authors: Xue W,Krishna BV,Bandyopadhyay A,Bose S

    更新日期:2007-11-01 00:00:00

  • Enzymatic conjugation of a bioactive peptide into an injectable hyaluronic acid-tyramine hydrogel system to promote the formation of functional vasculature.

    abstract::In this study, one-step enzyme-mediated preparation of a multi-functional injectable hyaluronic-acid-based hydrogel system is reported. Hydrogel was formed through the in situ coupling of phenol moieties by horseradish peroxidase (HRP) and hydrogen peroxide (H2O2), and bioactive peptides were simultaneously conjugated...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2014.02.022

    authors: Wang LS,Lee F,Lim J,Du C,Wan AC,Lee SS,Kurisawa M

    更新日期:2014-06-01 00:00:00

  • High transfection efficiency promoted by tailor-made cationic tri-block copolymer-based nanoparticles.

    abstract::Cationic polymer-based vectors have been considered a promising strategy in gene therapy area due to their inherent ability to condense genetic material and successfully transfect cells. However, they usually exhibit high cytotoxicity. In this work, it is proposed the use of a tailor-made gene carrier based on a tri-b...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2016.10.015

    authors: Cordeiro RA,Santo D,Farinha D,Serra A,Faneca H,Coelho JFJ

    更新日期:2017-01-01 00:00:00

  • Mechanically enhanced nested-network hydrogels as a coating material for biomedical devices.

    abstract::Well-organized composite formations such as hierarchical nested-network (NN) structure in bone tissue and reticular connective tissue present remarkable mechanical strength and play a crucial role in achieving physical and biological functions for living organisms. Inspired by these delicate microstructures in nature,...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2018.02.003

    authors: Wang Z,Zhang H,Chu AJ,Jackson J,Lin K,Lim CJ,Lange D,Chiao M

    更新日期:2018-04-01 00:00:00

  • Targeted proteomics effectively quantifies differences between native lung and detergent-decellularized lung extracellular matrices.

    abstract::Extracellular matrix is a key component of many products in regenerative medicine. Multiple regenerative medicine products currently in the clinic are comprised of human or xenogeneic extracellular matrix. In addition, whole-organ regeneration exploits decellularized native organs as scaffolds for organotypic cell cul...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2016.09.043

    authors: Calle EA,Hill RC,Leiby KL,Le AV,Gard AL,Madri JA,Hansen KC,Niklason LE

    更新日期:2016-12-01 00:00:00

  • Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation.

    abstract::Hydrogels that solidify in response to a dual, physical and chemical, mechanism upon temperature increase were fabricated and characterized. The hydrogels were based on N-isopropylacrylamide, which renders them thermoresponsive, and contained covalently cross-linkable moieties in the macromers. The effects of the macr...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2010.12.027

    authors: Klouda L,Perkins KR,Watson BM,Hacker MC,Bryant SJ,Raphael RM,Kasper FK,Mikos AG

    更新日期:2011-04-01 00:00:00

  • Matrix stiffening induces endothelial dysfunction via the TRPV4/microRNA-6740/endothelin-1 mechanotransduction pathway.

    abstract::Vascular stiffening is associated with the prognosis of cardiovascular disease (CVD). Endothelial dysfunction, as shown by reduced vasodilation and increased vasoconstriction, not only affects vascular tone, but also accelerates the progression of CVD. However, the precise effect of vascular stiffening on endothelial ...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2019.10.013

    authors: Song X,Sun Z,Chen G,Shang P,You G,Zhao J,Liu S,Han D,Zhou H

    更新日期:2019-12-01 00:00:00

  • A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: A case of an IR-780 derivative co-assembled with camptothecin prodrug.

    abstract::Self-assembled nanovehicles of chemotherapy drug with photothermal agent are regarded as intriguing chemo-photothermal therapy nanoplatform. However, most of the drugs and photothermal agents have poor water solubility and poor interactions to drive the formation of self-assembled nanovehicles, which is a bottleneck o...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2018.11.049

    authors: He W,Jiang Y,Li Q,Zhang D,Li Z,Luan Y

    更新日期:2019-01-15 00:00:00

  • Effect of nanostructure on osteoinduction of porous biphasic calcium phosphate ceramics.

    abstract::In order to evaluate the effect of the nanostructure of calcium phosphate ceramics on osteoinductive potential, porous biphasic calcium phosphate (BCP) ceramics with a nano- or submicron structure were prepared via microwave sintering and compared to conventional BCP ceramics. The selective protein adsorption of bovin...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章,收录出版

    doi:10.1016/j.actbio.2012.06.021

    authors: Li B,Liao X,Zheng L,Zhu X,Wang Z,Fan H,Zhang X

    更新日期:2012-10-01 00:00:00

  • Strut size and surface area effects on long-term in vivo degradation in computer designed poly(L-lactic acid) three-dimensional porous scaffolds.

    abstract::Current developments in computer-aided design (CAD) and solid free-form fabrication (SFF) techniques enable fabrication of scaffolds with precisely designed architectures and mechanical properties. The present study demonstrates the effect of precisely designed three-dimensional scaffold architectures on in vivo degra...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2012.03.028

    authors: Saito E,Liu Y,Migneco F,Hollister SJ

    更新日期:2012-07-01 00:00:00

  • Effect of hydrophilic polymer conjugation on heat-induced conformational changes in a protein.

    abstract::End-functional 2-methacryloyloxyethyl phosphorylcholine (MPC) co-polymers containing two different monomer units, 2-hydroxyethyl methacrylate (HEMA) and n-butyl methacrylate (BMA), with varying hydrophilicities were synthesized to investigate the effect of the conjugated hydrophilic polymer on the heat-induced conform...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2010.11.027

    authors: Seo JH,Matsuno R,Lee Y,Konno T,Takai M,Ishihara K

    更新日期:2011-04-01 00:00:00

  • Small intestinal submucosa gel as a potential scaffolding material for cardiac tissue engineering.

    abstract::Cardiac tissue engineering typically utilizes protein-rich scaffolding materials and growth factors to improve cardiac tissue function in vitro and in vivo. The objectives of this preliminary study were (i) to investigate the potential of porcine small intestinal submucosa gel (SIS gel) in cardiac tissue engineering a...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2009.10.048

    authors: Crapo PM,Wang Y

    更新日期:2010-06-01 00:00:00

  • Chemical surface alteration of biodegradable magnesium exposed to corrosion media.

    abstract::The understanding of corrosion processes of metal implants in the human body is a key problem in modern biomaterial science. Because of the complicated and adjustable in vivo environment, in vitro experiments require the analysis of various physiological corrosion media to elucidate the underlying mechanism of "biolog...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2011.03.004

    authors: Willumeit R,Fischer J,Feyerabend F,Hort N,Bismayer U,Heidrich S,Mihailova B

    更新日期:2011-06-01 00:00:00

  • Magnesium alloys for temporary implants in osteosynthesis: in vivo studies of their degradation and interaction with bone.

    abstract::This study investigates the bone and tissue response to degrading magnesium pin implants in the growing rat skeleton by continuous in vivo microfocus computed tomography (μCT) monitoring over the entire pin degradation period, with special focus on bone remodeling after implant dissolution. The influence of gas releas...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2011.11.008

    authors: Kraus T,Fischerauer SF,Hänzi AC,Uggowitzer PJ,Löffler JF,Weinberg AM

    更新日期:2012-03-01 00:00:00

  • Porous silicon as a potential electrode material in a nerve repair setting: Tissue reactions.

    abstract::We compared porous silicon (pSi) with smooth Si as chip-implant surfaces in a nerve regeneration setting. Silicon chips can be used for recording neural activity and are potential nerve interface devices. A silicon chip with one smooth and one porous side inserted into a tube was used to bridge a 5 mm defect in rat sc...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2009.02.010

    authors: Johansson F,Wallman L,Danielsen N,Schouenborg J,Kanje M

    更新日期:2009-07-01 00:00:00

  • Effect of processing conditions of dicalcium phosphate cements on graft resorption and bone formation.

    abstract::Dicalcium phosphate cements (brushite and monetite) are resorbable biomaterials with osteoconductive potential for bone repair and regeneration that have yet to gain widespread commercial use. Brushite can be converted to monetite by heat treatments additionally resulting in various changes in the physico-chemical pro...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2017.02.022

    authors: Sheikh Z,Zhang YL,Tamimi F,Barralet J

    更新日期:2017-04-15 00:00:00

  • Mg-Zr-Sr alloys as biodegradable implant materials.

    abstract::Novel Mg-Zr-Sr alloys have recently been developed for use as biodegradable implant materials. The Mg-Zr-Sr alloys were prepared by diluting Mg-Zr and Mg-Sr master alloys with pure Mg. The impact of Zr and Sr on the mechanical and biological properties has been thoroughly examined. The microstructures and mechanical p...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2012.04.028

    authors: Li Y,Wen C,Mushahary D,Sravanthi R,Harishankar N,Pande G,Hodgson P

    更新日期:2012-08-01 00:00:00

  • Theoretical and experimental quantification of the role of diffusive chemogradients on neuritogenesis within three-dimensional collagen scaffolds.

    abstract::A critical challenge to regenerating close mimics of native axonal pathways under chronic neurodegenerative disease or injury conditions is the inability to stimulate, sustain and steer neurite outgrowth over a long distance, until they reach their intended targets. Understanding neurite outgrowth necessitates quantit...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2014.05.009

    authors: Kothapalli CR,Honarmandi P

    更新日期:2014-08-01 00:00:00

  • A biodegradable vascularizing membrane: a feasibility study.

    abstract::Regenerative medicine and in vivo biosensor applications require the formation of mature vascular networks for long-term success. This study investigated whether biodegradable porous membranes could induce the formation of a vascularized fibrous capsule and, if so, the effect of degradation kinetics on neovascularizat...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2007.03.003

    authors: Kaushiva A,Turzhitsky VM,Darmoc M,Backman V,Ameer GA

    更新日期:2007-09-01 00:00:00

  • Differential expression of genes involved in the acute innate immune response to intracortical microelectrodes.

    abstract::Higher order tasks in development for brain-computer interfacing applications require the invasiveness of intracortical microelectrodes. Unfortunately, the resulting inflammatory response contributes to the decline of detectable neural signal. The major components of the neuroinflammatory response to microelectrodes h...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2019.11.017

    authors: Bedell HW,Schaub NJ,Capadona JR,Ereifej ES

    更新日期:2020-01-15 00:00:00

  • Additive manufacturing of an elastic poly(ester)urethane for cartilage tissue engineering.

    abstract::Although a growing knowledge on the field of tissue engineering of articular cartilage exists, reconstruction or in-vitro growth of functional hyaline tissue still represents an unmet challenge. Despite the simplicity of the tissue in terms of cell population and absence of innervation and vascularization, the outstan...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2019.11.041

    authors: Camarero-Espinosa S,Calore A,Wilbers A,Harings J,Moroni L

    更新日期:2020-01-15 00:00:00

  • Physical equivalency of wild type and galactose α 1,3 galactose free porcine pericardium; a new source material for bioprosthetic heart valves.

    abstract:UNLABELLED:Humans make high levels of antibody to carbohydrates with terminal galactose α 1,3 galactose (Gal) modifications. This Gal antigen is widely expressed in other mammals and is present on an array of current animal derived biomedical devices including bioprosthetic heart valves. There is growing interest in us...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2016.06.007

    authors: McGregor C,Byrne G,Rahmani B,Chisari E,Kyriakopoulou K,Burriesci G

    更新日期:2016-09-01 00:00:00

  • Self-reinforced composites of bioabsorbable polymer and bioactive glass with different bioactive glass contents. Part I: Initial mechanical properties and bioactivity.

    abstract::Spherical bioactive glass 13-93 particles, with a particle size distribution of 50-125 microm, were combined with bioabsorbable poly-L,DL-lactide 70/30 using twin-screw extrusion. The composite rods containing 0, 20, 30, 40 and 50 wt% of bioactive glass were further self-reinforced by drawing to a diameter of approxim...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2004.11.002

    authors: Niemelä T,Niiranen H,Kellomäki M,Törmälä P

    更新日期:2005-03-01 00:00:00

  • Impact of nanopore morphology on cell viability on mesoporous polymer and carbon surfaces.

    abstract::Topography at the nanoscale can lead to dramatic changes in the adhesion of cells to surfaces and their subsequent viability. For biological applications, including tissue engineering and cell-based sensing, the large internal surface area of ordered mesoporous carbons provides an opportunity for enhanced sensitivity ...

    journal_title:Acta biomaterialia

    pub_type: 杂志文章

    doi:10.1016/j.actbio.2010.02.005

    authors: Chavez VL,Song L,Barua S,Li X,Wu Q,Zhao D,Rege K,Vogt BD

    更新日期:2010-08-01 00:00:00