On the effect of a therapy able to modify both the growth rates in a Gompertz stochastic model.

Abstract:

:A Gompertz-type diffusion process characterized by the presence of exogenous factors in the drift term is considered. Such a process is able to describe the dynamics of populations in which both the intrinsic rates are modified by means of time-dependent terms. In order to quantify the effect of such terms the evaluation of the relative entropy is made. The first passage time problem through suitable boundaries is studied. Moreover, some simulation results are shown in order to capture the dependence of the involved functions on the parameters. Finally, an application to tumor growth is presented and simulation results are shown.

journal_name

Math Biosci

journal_title

Mathematical biosciences

authors

Albano G,Giorno V,Román-Román P,Torres-Ruiz F

doi

10.1016/j.mbs.2013.01.001

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

12-21

issue

1

eissn

0025-5564

issn

1879-3134

pii

S0025-5564(13)00025-4

journal_volume

245

pub_type

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