Genetic background, nutrition and obesity: a review.

Abstract:

OBJECTIVE:To summarize the latest information on the relationship between genes and common forms of obesity, and to review genetic markers (SNPs and miRNA) that play a role in predisposing to common forms of obesity and related disorders. MATERIALS AND METHODS:We searched PubMed with the following keywords: (obesity[Title/Abstract]) AND predisposition[Title/Abstract]) AND miRNA[Title/Abstract]) OR polymorphism[Title/Abstract]. RESULTS:From the search we obtained a total of 44 gene loci and 48 miRNAs associated with common obesity. CONCLUSIONS:It is now widely accepted that obesity involves interactions between environmental risk factors (physical inactivity, excessive calorie intake, chronic stress, taste perception) and a genetic background of risk. Analysis of the genetic background of obese subjects is therefore an important way to determine the molecular mechanisms controlling the link between food intake and obesity, enabling a better understanding of how these interactions may differ from person to person.

authors

Vettori A,Pompucci G,Paolini B,Del Ciondolo I,Bressan S,Dundar M,Kenanoğlu S,Unfer V,Bertelli M,Geneob Project.

doi

10.26355/eurrev_201902_17137

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

1751-1761

issue

4

eissn

1128-3602

issn

2284-0729

journal_volume

23

pub_type

杂志文章,评审
  • Use of cognitive enhancers: methylphenidate and analogs.

    abstract:OBJECTIVE:In the last decades, several cognitive-enhancing drugs have been sold onto the drug market. Methylphenidate and analogs represent a sub-class of these new psychoactive substances (NPS). We aimed to review the use and misuse of methylphenidate and analogs, and the risk associated. Moreover, we exhaustively rev...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:10.26355/eurrev_201901_16741

    authors: Carlier J,Giorgetti R,Varì MR,Pirani F,Ricci G,Busardò FP

    更新日期:2019-01-01 00:00:00

  • Effects of metoprolol and small intestine RNA on marrow-derived endothelial progenitor cells applied for autograft transplantation in heart disease.

    abstract:AIMS:The objective of this project was to improve the effect of EPC autograft transplantation and observe the tolerance of EPCs to I/R injury affected by metoprolol and small intestine RNA. MATERIALS AND METHODS:We isolated bone marrow-derived EPCs and examined the effects of metoprolol and small intestine RNA on EPCs...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Cheng K,Wei MQ,Jia GL,Wang HC,Luan RH,Guo WY,Li WJ,Zong XJ,Zhou X

    更新日期:2014-06-01 00:00:00

  • Observation of curative effect of recombinant human basic fibroblast growth factor combined with compound polymyxin B ointment and local application of insulin on wound healing of deep second-degree burn in diabetes mellitus: a randomized study.

    abstract:OBJECTIVE:We aimed at investigating the clinical efficacy of recombinant human basic fibroblast growth factor combined with compound polymyxin B ointment and the local application of insulin on wound healing of deep second-degree burn in diabetes mellitus. PATIENTS AND METHODS:80 diabetes mellitus patients complicated...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.26355/eurrev_201907_18345

    authors: Zhang JB,Li H,Zhang L,Wang JL

    更新日期:2019-07-01 00:00:00

  • Treatment of infantile hemangioma by intralesional injection of propranolol combined with compound betamethasone.

    abstract:OBJECTIVE:To explore the effective and convenient methods of infantile hemangioma treatment. PATIENTS AND METHODS:From October 2010 to June 2014, 31 infantile hemangioma patients admitted to our hospital, were administered propranolol combined with betamethasone injection treatment of lesions. RESULTS:All patients we...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Shao RZ,Zhao DH,Li J

    更新日期:2016-01-01 00:00:00

  • Downregulated miR-328 suppressed cell invasion and growth in hepatocellular carcinoma via targeting PTEN.

    abstract:OBJECTIVE:To investigate the regulatory effect of miR-328 on biological behaviors of hepatocellular carcinoma (HCC) cells, such as invasion and proliferation. PATIENTS AND METHODS:The expressions of miR-328 were detected in 48 pairs of HCC tissue samples and matched adjacent tissues, as well as in 3 kinds of HCC cell ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201810_16043

    authors: Liang F,Cui ZJ,Liu JD,Liu KP,Li L,Chen YL

    更新日期:2018-10-01 00:00:00

  • Nanoscale bubble delivered YCD-TK/Cx26 gene therapeutic system suppresses tumor growth by inducing necrosis of tumor tissues in mouse Xenograft bladder cancer models.

    abstract:OBJECTIVE:Bladder cancer is considered as the fifth most common cancer in the whole world. This study aimed to investigate the anti-tumor effects of Nanoscale bubbles delivered yeast cytosine deaminase thymidine kinase/connexin 26 (YCD-TK/Cx26) on tumor cell proliferation and tumor growth. MATERIALS AND METHODS:Nanosc...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201909_18839

    authors: Fu YR,Luo Y,Xie X,Lu W,Zhang R,Xiong B,Chen F

    更新日期:2019-09-01 00:00:00

  • Iloprost administration in acrodermatitis of Hallopeau complicated by acquired toes syndactyly: a case report and review of the literature.

    abstract:OBJECTIVE:Acrodermatitis Continua of Hallopeau (ACH) is a variant of pustular psoriasis often very difficult to treat. Secondary syndactyly, also called "pseudosyndactyly", is rare and can be a complication of burns, dystrophic epidermolysis bullosa or trauma. If left untreated, joint complications and definitive funct...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Segreto F,Tosi D,Marangi GF,Pendolino AL,Santoro S,Gigliofiorito P,Persichetti P

    更新日期:2015-08-01 00:00:00

  • Music therapy for coma patients: preliminary results.

    abstract:OBJECTIVE:The application of quantitative EEG (δ+θ/α+β value) and GCS value to evaluate the role of music therapy for traumatic brain injury coma patients. PATIENTS AND METHODS:Forty patients of traumatic brain injury coma were selected to meet the inclusion criteria. Twenty cases were selected for the rehabilitation,...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Sun J,Chen W

    更新日期:2015-04-01 00:00:00

  • Uniportal VATS for pectus excavatum: the Southern Switzerland experience.

    abstract:OBJECTIVE:The Nuss procedure is a minimally invasive approach used to treat the pectus excavatum. One to three curved metal bars are inserted behind the sternum in order to push it into a normal position. A bilateral thoracoscopy, with 3 or 4 incisions on each side, has been reported as a safe method to repair the ches...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202009_22843

    authors: Cafarotti S,Memoli E,Patella M,Rugel G,Minerva EM,Mendoza CM,Tessitore A,Hamitaga F

    更新日期:2020-09-01 00:00:00

  • LncRNA Bmncr alleviates the progression of osteoporosis by inhibiting RANML-induced osteoclast differentiation.

    abstract:OBJECTIVE:To elucidate whether long non-coding RNA (lncRNA) Bmncr could inhibit RANML-induced osteoclast differentiation, thus alleviating the progression of osteoporosis. MATERIALS AND METHODS:Expression level of lncRNA Bmncr at different stages of osteoclast differentiation was detected by quantitative Real Time-Pol...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201911_19411

    authors: Chen RS,Zhang XB,Zhu XT,Wang CS

    更新日期:2019-11-01 00:00:00

  • Correlations of degree of coronary artery stenosis with blood lipid, CRP, Hcy, GGT, SCD36 and fibrinogen levels in elderly patients with coronary heart disease.

    abstract:OBJECTIVE:To explore the correlations between the degree of coronary artery stenosis with blood lipid, C-reactive protein (CRP), homocysteine (Hcy), gamma-glutamyl transpeptidase (GGT), soluble cluster determinant 36 (sCD36), and fibrinogen (Fib) levels in elderly patients with coronary heart disease. PATIENTS AND MET...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201911_19453

    authors: Han K,Lu Q,Zhu WJ,Wang TZ,Du Y,Bai L

    更新日期:2019-11-01 00:00:00

  • Long noncoding RNA UCA1 promotes proliferation and metastasis of thyroid cancer cells by sponging miR-497-3p.

    abstract::Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Long noncoding RNA UCA1 promotes proliferation and metastasis of thyroid cancer cells by sponging miR-497-3p, by H. Gao, J.-Y. Yang, L.-X. Tong, H. Jin, C...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202007_22203

    authors: Gao H,Yang JY,Tong LX,Jin H,Liu CZ

    更新日期:2020-07-01 00:00:00

  • Hospital reengineering against COVID-19 outbreak: 1-month experience of an Italian tertiary care center.

    abstract:OBJECTIVE:The recent outbreak of SARS-CoV-2 infection in Italy has resulted in a sudden and massive flow of patients into emergency rooms, and a high number of hospitalizations with the need for respiratory isolation. Massive admission of patients to the Policlinico "Agostino Gemelli" Foundation of Rome, Italy, determi...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202008_22509

    authors: Tosoni A,Rizzatti G,Nicolotti N,Di Giambenedetto S,Addolorato G,Franceschi F,Zileri Dal Verme L,Gemelli Against COVID-19 Clinician Team (GAC-19 CT) Study Group.

    更新日期:2020-08-01 00:00:00

  • Effect of rosiglitazone on myocardial injury in septic rats through NF-κB pathway.

    abstract:INTRODUCTION:To explore the effect of rosiglitazone on myocardial injury in septic rats through the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway. MATERIALS AND METHODS:A total of 60 healthy adult female Sprague-Dawley (SD) rats were randomly divided into 4 groups, namely, group A (sep...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202001_19945

    authors: Zhang SM,Cai XF,Ma YL,Lu Q

    更新日期:2020-01-01 00:00:00

  • Prevention of neural tube defects and maternal gestational diabetes through the inositol supplementation: preliminary results.

    abstract:OBJECTIVE:Our study aims to demonstrate that the use in the preconceptional period until the 24th week of pregnancy of inositol and folic acid, first of all, preserves the product of conception from neural tube defects (NTDs) and then, thanks to inositol supplementation, it possibly counteracts and prevents the onset o...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Dell'Edera D,Sarlo F,Allegretti A,Epifania AA,Simone F,Lupo MG,Benedetto M,D'Apice MR,Capalbo A

    更新日期:2017-07-01 00:00:00

  • MiR-124a inhibits proliferation and invasion of rheumatoid arthritis synovial fibroblasts.

    abstract:OBJECTIVE:To investigate the impact of miR-124Aa on the proliferation, invasion and cytokine excretion of rheumatoid arthritis synovial fibroblasts (RASFs) in patients with rheumatoid arthritis (RA). PATIENTS AND METHODS:RASFs were separated for in-vitro culture, and transfected using lipidosome that connected with ch...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201807_15515

    authors: Li J,Song Q,Shao L,Zhang LL,Guo XH,Mao YJ

    更新日期:2018-07-01 00:00:00

  • MiR-32-5p regulates the proliferation and metastasis of cervical cancer cells by targeting HOXB8.

    abstract:OBJECTIVE:To investigate the effects of miR-32-5p on the biological behaviors of cervical cancer (CCa), the relevant mechanism was studied in CCa cell lines (HeLa) in vitro. PATIENTS AND METHODS:The expression level of miR-32-5p was detected by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Ta...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201901_16752

    authors: Liu YJ,Zhou HG,Chen LH,Qu DC,Wang CJ,Xia ZY,Zheng JH

    更新日期:2019-01-01 00:00:00

  • Prurigo nodularis of Hyde treated with low-dose thalidomide.

    abstract::Prurigo nodularis of Hyde is a skin disorder characterized by pruritic excoriated nodules. Improvement in pruritus and decrease in nodules was demonstrated in patients treated with oral thalidomide 200-400 mg daily. We report a case of a 52 year old woman with a history of widespread, persistent, and intensely pruriti...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Orlando A,Renna S,Cottone M

    更新日期:2009-03-01 00:00:00

  • Long noncoding RNA ROR1-AS1 induces tumor metastasis and epithelial-mesenchymal transition by sponging miR-375 in nasopharyngeal carcinoma.

    abstract:OBJECTIVE:The vital role of long noncoding RNAs (lncRNAs) in tumor progression has been identified in numerous studies. Nasopharyngeal carcinoma (NPC) is one of the most ordinary malignant tumors. This study aims to explore the role of lncRNA ROR1-AS1 in the metastasis of NPC. PATIENTS AND METHODS:Real Time-quantitati...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,收录出版

    doi:10.26355/eurrev_202001_19909

    authors: Hou J,Yan J,Ren XY,Zhu K,Du XY,Li JJ,Xu M

    更新日期:2020-01-01 00:00:00

  • Treatment of 741 Italian patients with chronic fatigue syndrome.

    abstract:BACKGROUND:Chronic Fatigue Syndrome (CFS) is a distinctive syndrome characterized by specific symptoms cluster. CFS mostly affects women and often results in severe functional limitation. Its prevalence varies from 0.4 to 2.5% in the general population. In our prior studies on the clinical features of 205 CFS patients ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Tirelli U,Lleshi A,Berretta M,Spina M,Talamini R,Giacalone A

    更新日期:2013-11-01 00:00:00

  • LncRNA DCST1-AS1 accelerates the proliferation, metastasis and autophagy of hepatocellular carcinoma cell by AKT/mTOR signaling pathways.

    abstract:OBJECTIVE:The previous research revealed that long noncoding RNAs (lncRNAs) play a vital role in the development of hepatocellular carcinoma (HCC). To further discuss the underlying mechanisms of lncRNA DCST1-AS1 in the pathogenesis of HCC. PATIENTS AND METHODS:We screened the abnormally expressed genes in HCC tissues...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201907_18423

    authors: Li J,Zhai DS,Huang Q,Chen HL,Zhang Z,Tan QF

    更新日期:2019-07-01 00:00:00

  • Role of radiography and ultrasonography in the diagnosis of the pediatric gastro-esophageal reflux disease.

    abstract::Twenty-four hour esophageal pH-monitoring is gold standard for evaluate pathological GERD. Role of radiography and ultrasonography in the diagnosis of gastro-esophageal reflux disease (GERD) has been studied. Our results have been shown that radiography and ultrasonography have a limited role in the diagnosis of patho...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Matrunola M,Grandin A,Mazza ML,Panetta A,Giardini V,Corrado G

    更新日期:2003-09-01 00:00:00

  • Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations.

    abstract:OBJECTIVES:The aim of the present study is to assess the implant osteointegration, as well as the course of bone regeneration and healing processes, thanks to the sinus lift procedure and by using PRF as a filling material, in association with the Bio-Oss. MATERIALS AND METHODS:23 patients, requiring maxillary sinus l...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 临床试验,杂志文章

    doi:

    authors: Inchingolo F,Tatullo M,Marrelli M,Inchingolo AM,Scacco S,Inchingolo AD,Dipalma G,Vermesan D,Abbinante A,Cagiano R

    更新日期:2010-12-01 00:00:00

  • Pneumatosis intestinalis: a rare cause of lower gastrointestinal bleeding.

    abstract::Pneumatosis intestinalis is an uncommon condition characterized by the presence of gas in the bowel wall. We present the case of a 49-year-old man admitted to our Clinic for his 4 day long haematochezia. Colonoscopy revealed pneumatosis coli as a cause of the lower gastrointestinal bleeding. A wide range of diagnostic...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Burgazli KM,Mericliler M,Greiner H,Göbel T,Erhardt A

    更新日期:2013-09-01 00:00:00

  • Dynamic changes of the various cytokines following carotid artery stenting.

    abstract:OBJECTIVE:To observe the serum inflammatory and coagulation factors changes and clinical significance following carotid artery stenting. PATIENTS AND METHODS:The expressions of serum inflammatory factors including IL-2, IL-6, IL-8, sICAM-1, hs-CRP, and TNF-α and serum coagulation factors including prothrombin time (PT...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Jia XJ,Fang SZ,Zhu QF,Xie RT,Liu ZY

    更新日期:2014-10-01 00:00:00

  • Diverse effects of taurine on vascular response and inflammation in GSH depletion model in rabbits.

    abstract:OBJECTIVE:A reduction in GSH and an increase in free radicals are observed in inflammatory diseases, indicating oxidative stress. Taurine protects cells from the cytotoxic effects of inflammation. There have been limited studies to date evaluating the effect of taurine in oxidative stress-induced vascular dysfunction a...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Ozsarlak-Sozer G,Sevin G,Ozgur HH,Yetik-Anacak G,Kerry Z

    更新日期:2016-04-01 00:00:00

  • MiRNA-138-5p protects the early diabetic retinopathy by regulating NOVA1.

    abstract:OBJECTIVE:To elucidate the function of miRNA-138-5p in the early diabetic retinopathy (DR) and the potential mechanism. MATERIALS AND METHODS:DR model in rats was first established by streptozotocin (STZ) injection. MiRNA-138-5p expression in rat retinal tissues was determined by quantitative Real Time-Polymerase Chai...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201909_18984

    authors: Bao XY,Cao J

    更新日期:2019-09-01 00:00:00

  • Effects of SIRT1/Akt pathway on chronic inflammatory response and lung function in patients with asthma.

    abstract:OBJECTIVE:Asthma is the most common chronic airway inflammatory disease. Sirtuin 1 (SIRT1) exerts a crucial effect on regulating chronic inflammatory responses. Therefore, this study aims to explore the effect of SIRT1 on the pathogenesis of asthma. MATERIALS AND METHODS:Serum level of SIRT1 in asthma patients and hea...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201906_18085

    authors: Zhang YZ,Wu QJ,Yang X,Xing XX,Chen YY,Wang H

    更新日期:2019-06-01 00:00:00

  • Oxidative stress tests: overview on reliability and use. Part I.

    abstract::Monitoring oxidative stress in humans is achieved by assaying products of oxidative damage or by investigating the potential of an organism, tissue or body fluids to withstand further oxidation. Unfortunately, there is little consensus concerning the selection of parameters of oxidative stress or antioxidant state to ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Palmieri B,Sblendorio V

    更新日期:2007-09-01 00:00:00

  • Biological therapies in autoimmune chronic inflammatory diseases (ACIDs).

    abstract::Autoimmune chronic inflammatory diseases (ACIDs) represent a growing part of chronic diseases and their cellular and molecular pathways have been deeply investigated in recent years in order to disclose some clue aspects that could be optimal targets of specific therapies. Among the autoimmune rheumatic diseases a maj...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Ferraccioli GF,Gremese E

    更新日期:2006-01-01 00:00:00