当前位置： SCI文献检索 > DIGESTIVE DISEASES AND SCIENCES期刊下所有文献 > Risk of Early Colorectal Cancers Needs to Be Considered in Inflammatory Bowel Disease Care.

Risk of Early Colorectal Cancers Needs to Be Considered in Inflammatory Bowel Disease Care.

Abstract：

BACKGROUND:Current guidelines recommend starting colorectal cancer (CRC) surveillance 8-10 years after inflammatory bowel disease (IBD) onset. Recent studies report that the incidence of CRC within 8-10 years of IBD onset (i.e., early CRC) ranges from 12 to 42%. AIMS:To describe the current prevalence of early CRC in a tertiary care center IBD cohort with CRC and to identify associated risk factors. METHODS:We performed a single-center observational study of IBD patients diagnosed with CRC from 2005 to 2015. We compared characteristics of patients with early CRC (diagnosis of CRC within 8 years of initial IBD onset) to those with CRC diagnosed later in their IBD course. RESULTS:Ninety-three patients met inclusion criteria. Eleven (11.8%) patients developed CRC within 8 years of initial IBD onset. On multivariable logistic regression, age greater than 28 at IBD onset (adjusted OR 12.0; 95% CI 2.30, 62.75) and tobacco use (adjusted OR 8.52; 95% CI 1.38, 52.82) were significant predictors of early CRC. A validation cohort confirmed calibration and discrimination of the model. CONCLUSIONS:One out of every eight IBD patients with CRC developed their malignancy prior to the currently recommended timeframe for the initiation of surveillance colonoscopy. IBD onset at 28 years or older and tobacco use were identified as predictors of early CRC. Early CRC should be considered in discussions of cancer surveillance in this population. Prospective cohort studies are necessary to further analyze the impact of early CRC in IBD.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Cohen-Mekelburg S,Schneider Y,Gold S,Ghosh G,Rosenblatt R,Hajifathalian K,Scherl E,Schnoll-Sussman F,Katz P,Steinlauf A

doi

10.1007/s10620-019-05554-1

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

2273-2279

issue

8

eissn

0163-2116

issn

1573-2568

pii

10.1007/s10620-019-05554-1

journal_volume

64

pub_type

杂志文章

相关文献

DIGESTIVE DISEASES AND SCIENCES文献大全
  • Induction of murine TNBS colitis is strictly controlled by a modified method using continuous inhalation anesthesia with sevoflurane.

    abstract：BACKGROUND:Trinitrobenzenesulfonic acid (TNBS)-induced colitis is one of the most widely used experimental colitis models. However, there is no standard procedure for inducing colitis by TNBS because it is difficult to achieve a uniform distribution of colitis. We have developed a modified method of murine TNBS-induced...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-013-3023-0

    authors： Terai T,Osawa S,Tani S,Oishi S,Arai Y,Yamada T,Sugimoto M,Furuta T,Kanaoka S,Miyajima H,Sugimoto K

    更新日期：2014-07-01 00:00:00

  • Impact of water exchange colonoscopy on serum sodium and potassium levels: an observational study.

    abstract：BACKGROUND:Concerns over the hypothetical adverse effects of water absorption and the disturbance of serum sodium and potassium levels prompted a quality assurance evaluation of water exchange (WE) colonoscopy. AIM:The purpose of this study was to evaluate the balance of water infused and suctioned in WE colonoscopy, ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-013-2934-0

    authors： Leung JW,Siao-Salera R,Abramyan O,Mann SK,Ward G,Yen A,Gutierrez R,Leung FW

    更新日期：2014-03-01 00:00:00

  • Diffuse excess mucosal collagen in rectal biopsies facilitates differential diagnosis of solitary rectal ulcer syndrome from other inflammatory bowel diseases.

    abstract：:Solitary rectal ulcer syndrome (SRUS) is sufficiently uncommon that the clinician or general pathologist may lack familiarity with the disorder and may confuse it with other inflammatory bowel diseases. To evaluate the role of collagen staining in facilitating the differential diagnosis of SRUS, an initial open review...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01536986

    authors： Levine DS,Surawicz CM,Ajer TN,Dean PJ,Rubin CE

    更新日期：1988-11-01 00:00:00

  • Effects of somatostatin analog SMS 201-995 on enterotoxigenic diarrhea.

    abstract：:Somatostatin analog SMS 201-995 causes a dose-related suppression of the release and/or action of several gastrointestinal hormones and impairs several anterior pituitary functions. Some patients with illness involving abnormal hormonal activity have responded to treatment with SMS 201-995, including resolution of sev...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01296623

    authors： Greenberg RN

    更新日期：1991-12-01 00:00:00

  • Endoscopic Management of Biliary Leaks and Strictures After Living Donor Liver Transplantation: Optimizing Techniques for Successful Management.

    abstract：BACKGROUND AND AIMS:Biliary complications (BCs) occur in up to 40% of living donor liver transplant (LDLT) recipients. The aim of this study was to evaluate the efficacy of endoscopic therapy in the management of LDLT-related BCs. METHODS:A retrospective study of 100 LDLT recipients at a single transplant center over ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-016-4367-z

    authors： Elwir S,Thompson J,Amateau SK,Trikudanathan G,Attam R,Hassan M,Kandaswamy R,Pruett T,Lake J,Chinnakotla S,Freeman ML,Arain MA

    更新日期：2017-01-01 00:00:00

  • Impact of functional dyspepsia on quality of life.

    abstract：:Little information on functional status and well-being is available in patients with functional gastrointestinal disease. We aimed to evaluate whether quality of life is poorer in patients with functional dyspepsia. A consecutive sample of 73 patients with functional dyspepsia completed a validated questionnaire prior...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02064375

    authors： Talley NJ,Weaver AL,Zinsmeister AR

    更新日期：1995-03-01 00:00:00

  • Prooxidant properties of 5-aminosalicylic acid. Possible mechanism for its adverse side effects.

    abstract：:There is a growing body of experimental and clinical evidence to suggest that oral or rectal administration of 5-ASA or 5-ASA conjugates is associated with significant adverse side effects including pancreatitis, hepatitis, and renal toxicity. The objective of this study was to assess the ability of 5-ASA to interact ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01296008

    authors： Grisham MB,Ware K,Marshall S,Yamada T,Sandhu IS

    更新日期：1992-09-01 00:00:00

  • Bacterial Infection in Patients with Cirrhosis: Don't Get Bugged to Death.

    abstract：:Bacterial infection remains a leading cause of mortality and morbidity for patients with cirrhosis, with hospitalization, alterations in the intestinal microbiota, and therapeutic drugs all implicated in its development. Bacterial infections also remain the most common precipitant of acute-on-chronic liver failure, wi...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,评审

    doi：10.1007/s10620-019-05943-6

    authors： Cannon MD,Martin P,Carrion AF

    更新日期：2020-01-01 00:00:00

  • Increased susceptibility of rat gastric mucosa to ulcerogenic stimulation with aging. Role of capsaicin-sensitive sensory neurons.

    abstract：:We examined the influences of aging on gastric damage and gastric mucosal blood flow (GMBF) responses induced by acid back-diffusion, following the barrier disruption, and investigated the relation of capsaicin-sensitive sensory nerves to these changes. Male Fischer rats 3, 13, and 24 months old were used. Under ureth...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02093826

    authors： Miyake H,Inaba N,Kato S,Takeuchi K

    更新日期：1996-02-01 00:00:00

  • Can Sertraline and Nortriptyline Protect the Neurons in Submucosal and Myenteric Plexuses of Rat's Colon Against Stress?

    abstract：BACKGROUND:The colon is partly controlled by myenteric and submucosal plexuses, which respond to stress and lead to some gastrointestinal disorders. These plexuses play roles in irritable bowel syndrome. Patients suffering from this syndrome can be treated with some antidepressants, including sertraline and nortriptyli...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-019-05600-y

    authors： Noorafshan A,Yousefi M,Hosseini L,Karbalay-Doust S

    更新日期：2019-09-01 00:00:00

  • Nitric oxide as a modulator of intestinal water and electrolyte transport.

    abstract：:The role of nitric oxide in intestinal fluid and electrolyte secretion depends upon whether the conditions under study are physiological or pathophysiological. In physiological conditions, endogenous nitric oxide seems to be a proabsorptive molecule, based on the findings that nitric oxide synthase inhibitors reverse ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,评审

    doi：10.1023/a:1018887525293

    authors： Izzo AA,Mascolo N,Capasso F

    更新日期：1998-08-01 00:00:00

  • Muscle shortening along the normal esophagus during swallowing.

    abstract：:Longitudinal shortening of the esophagus during peristaltic contraction has been previously analyzed globally using spaced mucosal clips. This method gives a relatively crude measurement. In this study, local longitudinal shortening (LLS) was evaluated using simultaneous high-resolution endoluminal ultrasound (HREUS) ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-006-3092-4

    authors： Dai Q,Korimilli A,Thangada VK,Chung CY,Parkman H,Brasseur J,Miller LS

    更新日期：2006-01-01 00:00:00

  • Children with celiac disease are more likely to have attended hospital for prior respiratory syncytial virus infection.

    abstract：BACKGROUND AND AIM:The purpose of this study was to examine the association between celiac disease (CD) and prior respiratory syncytial virus (RSV) infection or any viral bronchiolitis. METHODS:This was a retrospective case-control study. During 2006-2008 small intestinal biopsy data were collected from Sweden's 28 pa...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-014-3046-1

    authors： Tjernberg AR,Ludvigsson JF

    更新日期：2014-07-01 00:00:00

  • Reevaluation of manometric criteria for vigorous achalasia. Is this a distinct clinical disorder?

    abstract：:Clinical and manometric data from 97 consecutive patients with idiopathic achalasia were analyzed to see if a distinct subset with vigorous achalasia could be identified. Statistical analyses failed to detect a unique group of subjects based on the distribution of contraction wave amplitudes alone. Because of this, pa...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01318195

    authors： Todorczuk JR,Aliperti G,Staiano A,Clouse RE

    更新日期：1991-03-01 00:00:00

  • Gallbladder motility, gallstones, and the surgeon.

    abstract：:Cholecystectomy is one of the commonest surgical procedures in the Western world, with more than half a million procedures performed annually in the United States alone. In recent years, studies of gallstone pathogenesis and gallbladder disease have increasingly focused on abnormal gallbladder motility in the pathogen...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,评审

    doi：10.1007/BF02063233

    authors： Patankar R,Ozmen MM,Bailey IS,Johnson CD

    更新日期：1995-11-01 00:00:00

  • Enhanced expression of transforming growth factor (TGF) -alpha precursor and TGF-beta1 during Paneth cell regeneration.

    abstract：:An intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induces selective killing and rapid regeneration of Paneth cells, which have a large amount of zinc in their cytoplasmic granules. We examined the expression pattern of transforming growth factor (TGF) -alpha and TGF-beta1 in this regenera...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1010797609041

    authors： Seno H,Sawada M,Fukuzawa H,Morita Y,Takaishi S,Hiai H,Chiba T

    更新日期：2001-05-01 00:00:00

  • Diagnosis of malignant ascites. Comparison of ascitic fibronectin, cholesterol, and serum-ascites albumin difference.

    abstract：:The ascitic fluid concentrations of cholesterol and fibronectin and the serum-ascites albumin difference were compared with two conventional tests of ascitic fluid, total protein and LDH, in their diagnostic ability for detection of malignancy in ascitic samples from 69 patients with ascites: 54 with ascites due to li...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01550972

    authors： Prieto M,Gómez-Lechón MJ,Hoyos M,Castell JV,Carrasco D,Berenguer J

    更新日期：1988-07-01 00:00:00

  • Subtypes of muscarinic receptors in vagal inhibitory pathway to the lower esophageal sphincter of the opossum.

    abstract：:We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measurements were made of LES relaxation before and after intravenous administr...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01300200

    authors： Gilbert RJ,Dodds WJ

    更新日期：1987-10-01 00:00:00

  • Second harmonic generation imaging distinguishes both high-grade dysplasia and cancer from normal colonic mucosa.

    abstract：BACKGROUND AND AIM:Second harmonic generation (SHG) is a novel imaging technology that could provide optical biopsy during endoscopy with advantages over current technology. SHG has the unique ability to evaluate the amount of extracellular matrix collagen protein and its alignment. METHODS:Hematoxylin- and eosin-stai...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-014-3121-7

    authors： Birk JW,Tadros M,Moezardalan K,Nadyarnykh O,Forouhar F,Anderson J,Campagnola P

    更新日期：2014-07-01 00:00:00

  • Hepatitis C virus infection--pathobiology and implications for new therapeutic options.

    abstract：:Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,评审

    doi：10.1007/s10620-006-9484-7

    authors： Davis GL,Krawczynski K,Szabo G

    更新日期：2007-04-01 00:00:00

  • Minidose aspirin and gastrointestinal bleeding--a retrospective, case-control study in hospitalized patients.

    abstract：:Low or minimal doses of aspirin are widely used for prevention of cardiovascular diseases. Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation. Less is known about the risk associated with minidose aspirin. Our aim was to assess the possible association of upper gastro...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-005-2906-0

    authors： Sapoznikov B,Vilkin A,Hershkovici M,Fishman M,Eliakim R,Niv Y

    更新日期：2005-09-01 00:00:00

  • Bowel sounds analysis: a novel noninvasive method for diagnosis of small-volume ascites.

    abstract：:Ascites is more difficult to detect when only a small quantity is present. The aim of this pilot study was to determine the optimal bowel sound characteristics in order to distinguish no ascites from small-volume ascites by advanced processing of bowel sound wave patterns. This analysis results in the definition of th...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1024788428692

    authors： Liatsos C,Hadjileontiadis LJ,Mavrogiannis C,Patch D,Panas SM,Burroughs AK

    更新日期：2003-08-01 00:00:00

  • Possible role of oxygen free radicals in ethanol-induced gastric mucosal damage in rats.

    abstract：:The involvement of oxygen free radicals in the development of the ethanol-induced gastric mucosal damage has been investigated. We found that oral administration of superoxide dismutase reduced the incidence of ethanol-induced mucosal lesions. Reduction of superoxide dismutase activity by diethyldithiocarbamate led to...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01550977

    authors： Szelenyi I,Brune K

    更新日期：1988-07-01 00:00:00

  • Racial differences in epidemiology of irritable bowel syndrome alone, un-investigated dyspepsia alone, and "overlap syndrome" among african americans compared to Caucasians: a population-based study.

    abstract：:There is A paucity of data on racial differences in epidemiology of irritable bowel syndrome (IBS) alone and un-investigated dyspepsia (UD) alone compared to "overlap syndrome" (OS). We conducted a random survey (n = 990). Subjects completed a questionnaire which included Rome II criteria for IBS and functional dyspep...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-006-3112-4

    authors： Minocha A,Chad W,Do W,Johnson WD

    更新日期：2006-01-01 00:00:00

  • Analysis of Hospital-Based Emergency Department Visits for Inflammatory Bowel Disease in the USA.

    abstract：BACKGROUND:Inflammatory bowel disease (IBD) is a chronic, debilitating condition with high emergency department (ED) utilization. We aimed to investigate the utilization patterns of ED by IBD patients and measure hospitalization and surgical rates following ED visits. METHODS:We conducted a cross-sectional study of ad...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-015-3895-2

    authors： Gajendran M,Umapathy C,Loganathan P,Hashash JG,Koutroubakis IE,Binion DG

    更新日期：2016-02-01 00:00:00

  • Role of endoscopic retrograde pancreatography in pancreatic ascites.

    abstract：:We present a case of pancreatic ascites. The diagnosis was strongly suspected on the basis of ascitic fluid analysis and was confirmed by observation of pancreatic duct contrast leakage at endoscopic retrograde pancreatography (ERP). Computed tomography was not helpful in this case. For localization and final confirma...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02087571

    authors： Kuo YC,Wu CS

    更新日期：1994-05-01 00:00:00

  • Widespread changes in neurotransmitter expression and number of enteric neurons and interstitial cells of Cajal in lethal spotted mice: an explanation for persisting dysmotility after operation for Hirschsprung's disease?

    abstract：:Gastrointestinal motor dysfunction persists in a large number of children subjected to surgical treatment for Hirschsprung's disease, indicating abnormalities in the remaining intestine. The aim of the study was to detect possible alterations in frequency and topographic distribution of enteric neurons and interstitia...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1015085923245

    authors： Sandgren K,Larsson LT,Ekblad E

    更新日期：2002-05-01 00:00:00

  • Comparative study of plasma pancreatic polypeptide responses to food, secretin, and bombesin in normal subjects and in patients with chronic pancreatitis.

    abstract：:Plasma pancreatic polypeptide (PP) responses to food, secretin (1 CU/kg, intravenous) and bombesin (60 pmol/kg/20 min intravenous) were compared in 14 normal subjects and in 17 patients with chronic pancreatitis and pancreatic insufficiency. Basal plasma PP concentrations were significantly higher in normal subjects t...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01317049

    authors： Lamers CB,Diemel CM,Jansen JB

    更新日期：1984-02-01 00:00:00

  • Antiglycan antibodies in Greek patients with inflammatory bowel disease.

    abstract：BACKGROUND:Antiglycan antibodies have recently been reported to be associated with Crohn's disease (CD). These antibodies include anti-Saccharomyces cerevisiae mannan antibodies (ASCA), anti-laminariobioside carbohydrate antibodies (ALCA), anti-chitobioside carbohydrate antibodies (ACCA), and anti-mannobioside carbohyd...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-010-1328-9

    authors： Koutroubakis IE,Drygiannakis D,Tsirogianni A,Oustamanolakis P,Karmiris K,Papamichael K,Mantzaris GJ,Kouroumalis EA

    更新日期：2011-03-01 00:00:00

  • Gastric acid normosecretion is not essential in the pathogenesis of mild erosive gastroesophageal reflux disease in relation to Helicobacter pylori status.

    abstract：:In the pathogenesis of gastroesophageal reflux disease (GERD), gastric acid is considered to be one of the most important factors, but little is known about the degree of gastric acid secretion in GERD patients. In this study, we evaluated it in GERD patients and control subjects by 24-h intragastric pH, and serologic...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/b:ddas.0000030090.84412.2a

    authors： Shimatani T,Inoue M,Harada N,Horikawa Y,Nakamura M,Tazuma S

    更新日期：2004-05-01 00:00:00