Therapy of relapsing minimal-change disease in adults: a new approach?

Abstract:

:Multiple-relapsing minimal-change disease (MCD) often requires exposure to potentially toxic agents in an attempt to achieve a lasting remission of nephrotic syndrome. Munyentwali and co-workers describe an experience using rituximab in adults with multiple-relapsing MCD that supports both efficacy and safety of this agent. However, the optimal dosing regimen and mechanism of action remain unclear. Thus, randomized controlled trials are warranted in both adults and children to better define the role of rituximab in multiple-relapsing MCD.

journal_name

Kidney Int

journal_title

Kidney international

authors

Glassock RJ

doi

10.1038/ki.2012.412

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

343-5

issue

3

eissn

0085-2538

issn

1523-1755

pii

S0085-2538(15)55757-8

journal_volume

83

pub_type

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