Metabolic and cardiovascular effects of beta cell replacement in type 1 diabetes.

Abstract:

:Type 1 diabetes is associated with high morbidity and mortality, mostly due to the acute and chronic complications of the disease. Restoration of the lost beta cell mass by pancreas transplantation is the treatment of choice in selected type 1 diabetic patients. Growing data show that successful pancreas transplantation normalizes the metabolic alterations of diabetes, and can slow the progression, stabilize, and even favor the regression of secondary complications of the disease, including those at the cardiovascular level.

journal_name

Intern Emerg Med

authors

Marchetti P,Occhipinti M,Rondinini L,Mariotti R,Amorese G,Barsotti M,Vistoli F,Boggi U

doi

10.1007/s11739-013-0912-3

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

S55-6

eissn

1828-0447

issn

1970-9366

journal_volume

8 Suppl 1

pub_type

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