Abstract：
OBJECTIVE:To compare the effectiveness of intra-articular injection (IAI) with Botulinum toxin type A (BTA), triamcinolone hexacetonide (TH), and saline in primary knee osteoarthritis. DESIGN:A randomized controlled trial, with blinded patients and assessor. SETTING:Outpatient rheumatology service. SUBJECTS:Patients with knee osteoarthritis grades II and III. INTERVENTIONS:Patients received IAI with 100 IU BTA, 40 mg TH, or isotonic saline solution (SS) 0.9%. MAIN MEASURES:Patients were assessed at baseline and at 4, 8, and 12 weeks with the following instruments: visual analog scale for pain during movement (VASm; primary outcome) and visual analog scale for pain at rest (VASr), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, 6-minute walk test, Timed Up and Go test, Short Form (SF)-36 questionnaire, range of motion of knee, and ultrasound (US) measurement of synovial hypertrophy. RESULTS:In total, 105 patients were randomized, with 35 in each group; 96 were female (91.4%) and 9 were male (8.6%), with a mean age of 64.2 years (±6.9). At 12 weeks, the TH group showed better results only for VASm. At four weeks, the TH group showed better results than the BTA and SS groups for VASm (-68.9% (37.8) vs. -35.3% (40.3) vs. -35.9% (51.4)), WOMAC pain (-56.0% (30.7) vs. -30.8% (34.3) vs. -30.0% (39.9)), WOMAC stiffness (-53.4% (38.4) vs. -17.2% (59.3) vs. -17.3% (78.1)), WOMAC function (-48.2% (34.6) vs. 30.8% (33.6) vs. -13.6% (64.9)), WOMAC total score (-51.2% (31.0) vs. -30.9% (30.0) vs. -18.8% (54.8)), and US measurement of synovial hypertrophy (-11.6% (44.9) vs. -1.5% (47.9) vs. +28.6% (81.3)). CONCLUSION:IAI with TH had a higher effectiveness than that with TBA or SS in the short-term assessment (four weeks) for pain in movement, WOMAC, and US measurement of synovial hypertrophy.
journal_name
Clin Rehabiljournal_title
Clinical rehabilitationauthors
Mendes JG,Natour J,Nunes-Tamashiro JC,Toffolo SR,Rosenfeld A,Furtado RNVdoi
10.1177/0269215519827996subject
Has Abstractpub_date
2019-06-01 00:00:00pages
1015-1026issue
6eissn
0269-2155issn
1477-0873journal_volume
33pub_type
杂志文章,随机对照试验abstract：OBJECTIVE:To investigate the effect of early cycling training on balance and motor abilities of stroke patients in their subacute stage. DESIGN:Randomized clinical trial. SETTING:Inpatient rehabilitation. SUBJECTS:Twenty-four patients who had had a first stroke were randomly assigned to a cycling training group (N=1...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1191/0269215505cr960oa
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To determine the effects of pre- and postoperative inspiratory muscle training on length of postoperative hospital stay and pulmonary function in patients undergoing cardiac surgery. DESIGN AND METHODS:We conducted a systematic search using databases (MEDLINE, CINAHL, EMBASE, PEDro and the Cochrane) to find ...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1177/0269215516648754
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To describe the content and delivery of the adapted London Stroke Carers Training Course intervention evaluated in the Training Caregivers after Stroke (TRACS) trial. SETTING:The London Stroke Carers Training Course is a structured training programme for caregivers of inpatients who are likely to return home...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215514543334
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To evaluate cost, adherence and effects on cardiovascular function and quality of life of a home-based cardiac rehabilitation programme for patients with coronary disease. DESIGN:A randomized, prospective controlled trial. SETTING:Department of Rehabilitation, University Hospital, Brazil. SUBJECTS:Thirty-n...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215508093331
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:To compare the immediate effects of an external focus to enhance lateral body weight shift after stroke. DESIGN:Randomized controlled trial. SETTING:Inpatient rehabilitation hospital. SUBJECTS:Twenty patients after stroke (11 males; mean (SD) age 72.2 (7.4) years; duration of illness 56 (14) days; there we...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215513513963
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the reliability of assessing infants' general movements (GMs) using a new classification and its validity in predicting complex minor neurological dysfunction (MND) at toddler and at school age. DESIGN:Prospective study of two groups of infants, each consisting of a mix of low-risk and high-risk ...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1191/0269215504cr730oa
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:To determine the factors associated with physical activity participation in adults with hip or knee osteoarthritis. METHODS:A systematic review was conducted including searches of AMED, PsycINFO, CINAHL, MEDLINE, EMBASE, PubMed and the Cochrane Library from inception until October 2013. Studies presenting qu...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,评审
doi：10.1177/0269215514538069
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To review peer-reviewed literature relating to postoperative physiotherapy for degenerative cervical myelopathy (DCM), to determine efficacy in improving clinical outcome and recovery. DATA SOURCES:MEDLINE, EMBASE, CENTRAL, PEDro, ISRCTN registry, WHO ICTRP and Clinicaltrials.gov . References and citations o...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215518766229
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To develop and validate parallel short forms for the assessment of general anxiety in cardiovascular rehabilitation patients, that facilitate repeated measurement over time without contamination from residual practice effect variance. DESIGN:Development of the parallel short forms using Rasch analysis. Valid...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215515627288
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of modified wheelchair arm-support to mitigate hemiplegic shoulder pain and reduce pain frequency in stroke patients. DESIGN:A single-blind randomized controlled trial using computer-generated simple randomization. SETTING:Participants recruited from inpatients at the Guangdong Provin...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215517714830
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of a patient education programme for preventing falls in the subacute hospital setting. DESIGN:Randomized controlled trial, subgroup analysis. PARTICIPANTS:Patients of a metropolitan subacute/aged rehabilitation hospital who were recommended for a patient education intervention...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215506070694
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To identify psychometrically robust and clinically feasible measures of walking and mobility in people with neurological conditions. DATA SOURCES:MEDLINE, CINAHL, EMBASE, PEDro and AMED. REVIEW METHODS:Independent reviewers selected and extracted data from articles that assessed the reliability, validity, s...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,评审
doi：10.1177/0269215509339004
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of patellar taping on the electromyographic onset of vastus medialis obliquus and vastus lateralis, and their magnitudes of reflex contraction before and after quadriceps muscle fatigue in subjects with patellofemoral pain. METHODS:Sixteen adults (5 males) diagnosed with patellofem...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215509334835
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:This study aims to evaluate the prevalence and determinants of inadequate physical activity and excessive sedentary behaviour before and after total knee replacement. DESIGN, SETTING AND SUBJECTS:Secondary analysis was performed on data from a cohort of 422 adults (45-74 years), drawn from 12 public or priva...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215518769986
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to assess the efficacy of a patient-focused professionally guided self-care programme for the management of multiple sclerosis (MS) in the community. DESIGN:This was a single-blind randomized controlled trial. SETTING:The study was conducted with people with MS living in the communi...
journal_title：Clinical rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1191/0269215502cr478oa
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:To systematically review the evidence on the effect of continuous passive motion, combined with usual physiotherapy management, on increasing shoulder joint range of motion and muscle strength, and reducing shoulder pain in adults following rotator cuff repair, compared with standard physiotherapy. DATA SOUR...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,评审
doi：10.1177/0269215510380835
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:This study investigated the impact of the severity of parental multiple sclerosis, parents' expressed emotion and psychological well-being on offspring's psychological difficulties. DESIGN:A longitudinal study including baseline and 6-month follow-up data collected from parents and children. SUBJECTS:Adoles...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215515580600
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To examine the effect of constraint-induced movement therapy and modified constraint-induced movement therapy on activity and participation of patients with stroke (i.e. the effect of different treatment durations and frequency) by reviewing the results of randomized controlled trials. DATA SOURCES:A systema...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1177/0269215511420306
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of lifestyle group intervention on well-being, occupation and social participation. DESIGN:A randomized controlled trial. SETTING:Senior centres in the community. SUBJECTS:Of 204 stroke survivors screened, 99 (49%) were randomized three months after stroke whereby 86 (87%) par...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1177/0269215511429473
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of pre-emptive swallowing stimulation on the recovery of swallowing function in long-term intubated patients. DESIGN AND SUBJECTS:Patients in the intensive care unit intubated for at least 48 hours due to respiratory distress from March to August 2004 were randomly divided into two gro...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215506071286
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To compare spinal manipulation, back school and individual physiotherapy in the treatment of chronic low back pain. DESIGN:Randomized trial, 12-month follow-up. SETTING:Outpatient rehabilitation department. PARTICIPANTS:210 patients with chronic, non-specific low back pain, 140/210 women, age 59 +/- 14 yea...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215509342328
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To enhance our understanding of coping and rehabilitation in the context of adaptation to disability by examining how coping may change over a two-year time period, and how different vision rehabilitation services may affect coping over time. DESIGN:Longitudinal two-wave study (baseline and two-year follow-u...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1191/0269215506cr965oa
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:To assess the psychometric properties of an observational screening measure of depressive symptoms (SADQH-10; 10-item Hospital version of the Stroke Aphasic Depression Questionnaire) for use in stroke patients with aphasia and to determine the convergent and divergent validity of the SADQH-10. DESIGN:Cross-s...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215511422388
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE::We sought to (1) identify the outcome measures currently used across stroke arm rehabilitation randomized trials, (2) identify and compare outcomes important to stroke survivors, carers and clinicians and (3) describe where existing research outcome measures capture outcomes that matter the most to stroke su...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215518823248
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:To examine the scalability of the Rivermead Motor Assessment (RMA) with nonacute stroke patients in the community. DESIGN:This was a prospective study of the patients after discharge from hospital. All subjects were assessed on the RMA at six and 12 months after discharge home from hospital. Coefficients of ...
journal_title：Clinical rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/026921559701100108
更新日期：1997-02-01 00:00:00
abstract：OBJECTIVE:To modify a published group intervention for adjustment to multiple sclerosis (MS) to suit an individual format, and to assess the feasibility of a randomised controlled trial (RCT) to compare individual and group intervention for people with multiple sclerosis and low mood. DESIGN:Feasibility randomised con...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215515616446
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE::To explore the feasibility of a rehabilitation program and its effect on the performance-related musculoskeletal symptoms and functional limitations of orchestral musicians. DESIGN::Single-blind pilot randomized controlled trial with exercise group and control group. SETTING::Workplace of professional symp...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1177/0269215518785000
更新日期：2018-12-01 00:00:00
abstract：PRIMARY OBJECTIVE:To appraise recent studies regarding the needs and experiences of caregivers of individuals with multiple sclerosis (MS). DESIGN:The following computerized databases were searched: CINAHL, BIDS IBSS, ASSIA, MEDLINE, PSYCHINFO, British Nursing Index, ISI Web of Science, Zetoc, AMED (1990-April 2002). ...
journal_title：Clinical rehabilitation
pub_type： 杂志文章,评审
doi：10.1191/0269215503cr618oa
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To compare the feasibility, convergent and clinical validity of three commonly used burden scales: Caregiver Strain Index (CSI), Caregiver Reaction Assessment (CRA) and Sense of Competence Questionnaire (SCQ), with a self-developed single question on self-rated burden (SRB). SUBJECTS:Stroke patients receivin...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1191/0269215504cr723oa
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To provide clinical practitioners with a framework for teaching patients Time Pressure Management, a cognitive strategy that aims to reduce disabilities arising from mental slowness due to acquired brain injury. Time Pressure Management provides patients with compensatory strategies to deal with time pressure i...
journal_title：Clinical rehabilitation
pub_type： 杂志文章
doi：10.1177/0269215508097855
更新日期：2009-01-01 00:00:00
