Screening of new bioactive metabolites for diabetes therapy.

abstract：:The aim of this study was to relate in-hospital mortality (IHM), cardiovascular events (CVEs) and non-immunologic comorbidity evaluated on the basis of International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codification, in Italian kidney transplant recipients (KTRs). We evaluated IHM...

journal_title：Internal and emergency medicine

authors： Fabbian F,De Giorgi A,Manfredini F,Lamberti N,Forcellini S,Storari A,Todeschini P,Gallerani M,La Manna G,Mikhailidis DP,Manfredini R

更新日期：2016-09-01 00:00:00

abstract：:We sought to compare length-of-stay (LOS), total hospital costs, and readmissions among pulmonary embolism (PE) patients treated with rivaroxaban versus parenterally bridged warfarin. We identified adult PE (primary diagnostic code = 415.1x) patients in the Premier Database (11/2012-9/2015), and included those with ≥1...

journal_title：Internal and emergency medicine

authors： Weeda ER,Wells PS,Peacock WF,Fermann GJ,Baugh CW,Ashton V,Crivera C,Wildgoose P,Schein JR,Coleman CI

更新日期：2017-04-01 00:00:00

abstract：:Cirrhosis is characterized by a complex coagulation defect leading to the prolongation of the prothrombin and activated partial thromboplastin times (PT and APTT). Arbitrary PT cut-off values are still used as a yardstick to guide treatment with fresh-frozen plasma (FFP) or other pro-coagulant agents in patients under...

journal_title：Internal and emergency medicine

authors： Tripodi A,Chantarangkul V,Primignani M,Clerici M,Dell'era A,Aghemo A,Mannucci PM

更新日期：2012-04-01 00:00:00

abstract：:Despite the availability of updated guidelines for the diagnosis and treatment of venous thromboembolism (VTE), the management of this disorder in clinical practice is often not standardized, given the different degree of compliance with official recommendations by the various involved specialists. The aim of this con...

journal_title：Internal and emergency medicine

authors： Imberti D,Becattini C,Bernardi E,Camporese G,Cuccia C,Dentali F,Paretti D

更新日期：2018-10-01 00:00:00

abstract：:Inconsistent findings in the studies have been observed concerning the higher dose of statins use in the acute phase of ischemic stroke and transient ischemic attack (TIA). Therefore, we performed a systematic review to assess this issue. A computerized literature search in PubMed, Cochrane Library databases, and EMBA...

journal_title：Internal and emergency medicine

authors： Fang JX,Wang EQ,Wang W,Liu Y,Cheng G

更新日期：2017-08-01 00:00:00

abstract：:The objective of this study is to determine the prevalence of respiratory syncytial virus (RSV) and other viral respiratory pathogens in emergency department (ED) patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD patients presenting to the ED with <10 days of AECOPD symptoms wer...

journal_title：Internal and emergency medicine

authors： Camargo CA Jr,Ginde AA,Clark S,Cartwright CP,Falsey AR,Niewoehner DE

更新日期：2008-12-01 00:00:00

abstract：:Extreme hypomagnesemia (hypoMg) can be encountered in many situations, but little data currently exist. Our aim is to describe the epidemiological, clinical, etiological characteristics, and the biological abnormalities of consecutive inpatients with extreme hypomagnesemia. In our observational monocentric study, betw...

journal_title：Internal and emergency medicine

authors： Cheminet G,Clain G,Jannot AS,Ranque B,Passeron A,Michon A,De Luna G,Diehl JL,Oudard S,Cellier C,Karras A,Vedié B,Prot-Bertoye C,Pouchot J,Arlet JB

更新日期：2018-12-01 00:00:00

abstract：:Right ventricular (RV) function impacts the outcome in cardiac and pulmonary diseases such as heart failure, pulmonary hypertension, myocardial infarction, valvular, and congenital heart diseases. To our knowledge, simultaneous evaluation of left ventricular (LV) and RV systolic and diastolic echocardiographic indices...

journal_title：Internal and emergency medicine

authors： Giovanardi P,Tincani E,Rossi R,Agnoletto V,Bondi M,Modena MG

更新日期：2012-06-01 00:00:00

abstract：:A meta-analysis to determine the impact of gender on mortality in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS): PubMed, EMBASE, and Cochrane Library, was systematically searched. Two investigators independently reviewed retrieved articles and assessed eligibility. Unadjusted mortality rat...

journal_title：Internal and emergency medicine

authors： Wang Y,Zhu S,Du R,Zhou J,Chen Y,Zhang Q

更新日期：2018-03-01 00:00:00

abstract：:The article Reversal agents for oral anticoagulant-associated major or life-threatening bleeding, written by Marco Moia, Alessandro Squizzato was originally published electronically on the publisher's internet portal (currently SpringerLink) on 24 August 2019 without open access. ...

journal_title：Internal and emergency medicine

authors： Moia M,Squizzato A

更新日期：2020-06-01 00:00:00

abstract：:The idea of using small RNA fragments (oligonucleotides) for therapeutic purposes dates back to the 1990s, following the landmark discoveries on the mechanisms of gene silencing and RNA-interference (RNA-i). However, the first applications in medicine were hampered by difficulties in chemical stabilization and efficie...

journal_title：Internal and emergency medicine

authors： Girelli D,Busti F,Marchi G,Martinelli N,Olivieri O

更新日期：2018-04-01 00:00:00

abstract：:Assessing the effects of an antimicrobial stewardship program (ASP) implemented in a 78-bed Internal Medicine ward of an Italian mid-sized acute care hospital of 296 beds (26,820 bed days/year in 2015 and 26,653 in 2016). The ASP, implemented in May 2016, included: (a) formulation and dissemination of local guidelines...

journal_title：Internal and emergency medicine

authors： Fortini A,Faraone A,Di Pietro M,Cappugi C,Magnante G,Boccadori C,Bartolini S,Rabatti L

更新日期：2018-12-01 00:00:00

abstract：:This study aimed to compare the diagnostic accuracy of heart, lung and inferior vena cava (IVC) ultrasonography modalities, alone and combined, for possible added accuracy in diagnosing acute decompensated heart failure (ADHF), in a group of patients with the final diagnosis of ADHF based on plasma level of B-type nat...

journal_title：Internal and emergency medicine

authors： Farahmand S,Abdolhoseini A,Aliniagerdroudbari E,Babaniamansour S,Baratloo A,Bagheri-Hariri S

更新日期：2020-04-01 00:00:00

abstract：:In the original publication, the given name and family name of the fifth author Dr Margherita Migone De Amicis were incorrectly published. The correct given name and family name should read as 'Margherita' and 'Migone De Amicis', respectively. ...

journal_title：Internal and emergency medicine

authors： Londoño KL,Formiga F,Chivite D,Moreno-Gonzalez R,Migone De Amicis M,Corbella X

更新日期：2018-09-01 00:00:00

abstract：:Pulmonary hypertension (PH) is defined as an elevated mean pulmonary artery pressure at rest (mPAP ≥ 25 mmHg), evaluated by right heart catheterization (RHC). The aim of the present study was to evaluate HRCT findings in relation to transthoracic echocardiographic data to better characterize PH in IPF patients and to ...

journal_title：Internal and emergency medicine

authors： Refini RM,Bettini G,Kacerja E,Cameli P,d'Alessandro M,Bergantini L,De Negri F,Rottoli P,Sestini P,Bargagli E,Mazzei MA

更新日期：2020-11-05 00:00:00

abstract：:The CORP (COlchicine for Recurrent Pericarditis) trial [7]is a prospective, randomized, double-blind, placebo controlled, multicenter trial to evaluate the efficacy and safety of colchicine (1.0–2.0 mg on the first day, followed by a maintenance dose of 0.5–1.0 mg/day for 6 months) in association with conventional ant...

journal_title：Internal and emergency medicine

authors： Gianni F,Solbiati M,Gruppo di Autoformazione Metodologica (GrAM).

更新日期：2012-04-01 00:00:00

abstract：:Toxic alcohols are a group of substances containing a hydroxyl group not meant to be ingested. They are the cause of a significant number of accidental and non-accidental exposures. Toxic alcohol poisoning can be associated with a significant degree of morbidity and mortality if not promptly recognized and treated. Th...

journal_title：Internal and emergency medicine

authors： Ng PC,Long BJ,Davis WT,Sessions DJ,Koyfman A

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:In marathon runners changes in red blood cell count, haematocrit and haemoglobin in relation to haemodilution have been reported. Moreover, it has been hypothesized that strenuous exercise induces oxidant stress through several different mechanisms. This study investigated the haematological variables, iron s...

journal_title：Internal and emergency medicine

authors： Duca L,Da Ponte A,Cozzi M,Carbone A,Pomati M,Nava I,Cappellini MD,Fiorelli G

更新日期：2006-01-01 00:00:00

abstract：:Chronic hypersensitivity pneumonitis (cHP) is a fibrotic interstitial lung disease (ILD) resulting from inhalation of different organic substances and chemical compounds determining an inflammatory and immunological response in sensitized individuals. KL-6, a human mucin protein expressed by type 2 pneumocytes, has be...

journal_title：Internal and emergency medicine

authors： Lanzarone N,Gentili F,Alonzi V,Bergantini L,d'Alessandro M,Rottoli P,Refini RM,Pieroni M,Vietri L,Bianchi F,Mazzei MA,Volterrani L,Perrone A,Cameli P,Bargagli E,Sestini P

更新日期：2020-10-01 00:00:00

abstract：:Hypertension and diabetes are known risk factors for obesity-related thrombosis, but several studies have shown that obesity is characterised by a potentially prothrombotic inflammatory state because of activated coagulation and impaired fibrinolysis. In order to verify if obese patients-unaffected by hypertension, di...

journal_title：Internal and emergency medicine

authors： Cugno M,Castelli R,Mari D,Mozzi E,Zappa MA,Boscolo-Anzoletti M,Roviaro G,Mannucci PM

更新日期：2012-06-01 00:00:00

abstract：:The authors have investigated the incidence of acute kidney injury (AKI) and short-term mortality following an activated STEMI and stroke alert at a tertiary referral and academic center. A single center, retrospective chart review of STEMI and stroke activation patients from January 2010 to March 2012. Data was colle...

journal_title：Internal and emergency medicine

authors： Marchick MR,Allen BR,Weeks EC,Shuster JJ,Elie MC

更新日期：2016-09-01 00:00:00

abstract：:International guidelines recommend the use of pharmacological prophylaxis in hospitalized medical patients at high risk of venous thromboembolism (VTE). The same international guidelines suggest the employment of standardized risk assessment models (RAMs) when evaluating the administration of pharmacological prophylax...

journal_title：Internal and emergency medicine

authors： Depietri L,Marietta M,Scarlini S,Marcacci M,Corradini E,Pietrangelo A,Ventura P

更新日期：2018-06-01 00:00:00

abstract：:In non-ST-elevation acute coronary syndromes (ACS), an early invasive strategy is recommended for middle/high-risk patients; however, the optimal timing for coronary angiography is still debated. The aim of this study was to evaluate the prognostic implications of the time of angiography in ACS patients treated in acc...

journal_title：Internal and emergency medicine

authors： Giglioli C,Cecchi E,Landi D,Valente S,Chiostri M,Romano SM,Spini V,Perrotta L,Simonetti I,Gensini GF

更新日期：2013-03-01 00:00:00

abstract：:In older people, revisit to the emergency department (ED) in the short period after discharge is not entirely avoidable, but in a proportion of cases is preventable, and should ideally be minimised. We have previously derived a risk probability nomogram to predict the likelihood of revisit. In this study, we sought to...

journal_title：Internal and emergency medicine

authors： Arendts G,Etherton-Beer C,Jones R,Bullow K,MacDonald E,Dumas S,Parker D,Hutton M,Burrows S,Brown SG,Almeida OP

更新日期：2015-06-01 00:00:00

abstract：:Transjugular intrahepatic portosystemic shunt (TIPS) represents a very effective treatment of complications of portal hypertension. Established indications to TIPS in cirrhotic patients include portal hypertensive bleeding and refractory ascites. Over the years additional indications have been proposed, such as the tr...

journal_title：Internal and emergency medicine

authors： Vizzutti F,Schepis F,Arena U,Fanelli F,Gitto S,Aspite S,Turco L,Dragoni G,Laffi G,Marra F

更新日期：2020-01-01 00:00:00

abstract：:Increasing evidence shows an association between high lipoprotein(a) [Lp(a)] levels and atherothrombotic diseases. Lp(a) trait is largely controlled by kringle-IV type 2 (KIV-2) size polymorphism in LPA gene, encoding for apo(a). Environmental factors are considered to determinate minor phenotypic variability in Lp(a)...

journal_title：Internal and emergency medicine

authors： Sereni A,Sticchi E,Gori AM,Magi A,Della Latta D,Volta A,Murri A,Jamagidze G,Chiappino D,Abbate R,Gensini GF,Marcucci R,Sofi F,Giusti B

更新日期：2020-10-01 00:00:00

abstract：:Although ketamine has been used for procedural sedation and analgesia, some researchers have assessed ketamine-propofol as a better alternative because of its reduced adverse events. The goal of this review was to compare adverse events between ketamine-propofol and ketamine for procedural sedation and analgesia in ch...

journal_title：Internal and emergency medicine

authors： Hu Y,Xu W,Cao F

更新日期：2019-10-01 00:00:00

abstract：:Although chronic hypertension is associated with long-term complications, few studies directly examine the effects of in-hospital acute hypertensive episodes in trauma patients. The aim was to determine whether there is an association between in-hospital acute hypertension and morbidity. We included trauma patients be...

journal_title：Internal and emergency medicine

authors： Saliba L,Stawicki SP,Thongrong C,Bergese SD,Papadimos TJ,Gerlach AT

更新日期：2014-08-01 00:00:00

abstract：:Pain treatment in Italy is far from being optimal. In order to improve this situation, the reporting of a complete assessment of pain in the clinical record became compulsory by law. Pain-related cancer protocols (143) were selected from the National Monitoring Centre of Clinical Trials Database and reviewed. Our data...

journal_title：Internal and emergency medicine

authors： Lucenteforte E,Maggini V,Maione R,Fabbroni V,Tomino C,Mugelli A

更新日期：2013-10-01 00:00:00

abstract：:Cryoablation (CA) emerged as an alternative procedure to radiofrequency (RF). The aim of this study was to compare haemostatic system alterations in patients undergoing RF or CA for atrioventricular nodal reentrant tachycardia ablation. von Willebrand factor (vWF), spontaneous whole blood platelet aggregation, prothro...

journal_title：Internal and emergency medicine

authors： Pieragnoli P,Gori AM,Ricciardi G,Carrassa G,Checchi L,Michelucci A,Priora R,Cellai AP,Marcucci R,Padeletti L,Abbate R

更新日期：2014-12-01 00:00:00