Dynamic (99m)Tc-MAG3 renography: images for quality control obtained by combining pharmacokinetic modelling, an anthropomorphic computer phantom and Monte Carlo simulated scintillation camera imaging.

abstract：:In x-ray based imaging of the breast, contrast between fibroglandular (Fg) tissue and adipose (Ad) tissue is a source of anatomic noise. The goal of this work was to validate by simulation and experiment a mathematical framework for modelling the Fg component of anatomic noise in digital mammograpy (DM) and dual-energ...

journal_title：Physics in medicine and biology

authors： Tanguay J,Lalonde R,Bjarnason TA,Yang CJ

更新日期：2019-10-23 00:00:00

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00

abstract：:A clinical trial named PROMETHEUS is currently ongoing for inoperable hepatocellular carcinoma (HCC) at the Heidelberg Ion Beam Therapy Center (HIT, Germany). In this framework, 4D PET-CT datasets are acquired shortly after the therapeutic treatment to compare the irradiation induced PET image with a Monte Carlo PET p...

journal_title：Physics in medicine and biology

authors： Gianoli C,Kurz C,Riboldi M,Bauer J,Fontana G,Baroni G,Debus J,Parodi K

更新日期：2016-06-07 00:00:00

abstract：:The possible use of fluorescence bronchoscopy for localization of bronchogenic tumours at the carcinoma in situ stage has been investigated. The target lesion is 80 micrometer thick with a mass of 250 microgram, containing 250 pg of haematoporphyrin derivative. The injected haematoporphyrin-derivative is preferentiall...

journal_title：Physics in medicine and biology

authors： Profio AE,Doiron DR

更新日期：1977-09-01 00:00:00

abstract：:Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescence molecular tomogra...

journal_title：Physics in medicine and biology

authors： Lu Y,Zhu B,Shen H,Rasmussen JC,Wang G,Sevick-Muraca EM

更新日期：2010-08-21 00:00:00

abstract：:The free space method using a pair of lens antennas was modified for the complex permittivity measurement of biological samples from 20 to 110 GHz. Two methodologies were used to obtain the complex permittivities by the free space method, which were based on the reflection and transmission coefficients. The measuremen...

journal_title：Physics in medicine and biology

authors： Sasaki K,Segawa H,Mizuno M,Wake K,Watanabe S,Hashimoto O

更新日期：2013-03-07 00:00:00

abstract：:Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

更新日期：2017-06-07 00:00:00

abstract：:RapidArc, recently released by Varian Medical Systems, is a novel extension of IMRT in which an optimized 3D dose distribution may be delivered in a single gantry rotation of 360 degrees or less. The purpose of this study was to investigate the accuracy of the analytical anisotropic algorithm (AAA), the sole algorithm...

journal_title：Physics in medicine and biology

authors： Gagne IM,Ansbacher W,Zavgorodni S,Popescu C,Beckham WA

更新日期：2008-12-21 00:00:00

abstract：:A medical research protocol on clinical intravenous coronary angiography has been completed at the European Synchrotron Radiation Facility (ESRF) biomedical beamline. The aim was to investigate the accuracy of intravenous coronary angiography based on the K-edge digital subtraction technique for the detection of in-st...

journal_title：Physics in medicine and biology

authors： Sarnelli A,Nemoz C,Elleaume H,Estève F,Bertrand B,Bravin A

更新日期：2005-02-21 00:00:00

abstract：:A Geiger-mode avalanche photodiode (Si-PM) is a promising photodetector for PET, especially for use in a magnetic resonance imaging (MRI) system, because it has high gain and is less sensitive to a static magnetic field. We developed a Si-PM-based depth-of-interaction (DOI) PET system for small animals. Hamamatsu 4 × ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Imaizumi M,Watabe T,Watabe H,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2010-10-07 00:00:00

abstract：:Recent developments in the technique of constant infusion and in emission computed tomography have provided a new method for quantitative regional flow measurements. This paper re-examines critically the theoretical relationship between flow and radioactivity during constant infusion of short-lived isotopes. Sensitivi...

journal_title：Physics in medicine and biology

authors： Huang SC,Phelps ME,Hoffman EJ,Kuhl DE

更新日期：1979-11-01 00:00:00

abstract：:In vitro dielectric properties of ageing porcine tissues were measured in the frequency range of 50 MHz-20 GHz, and the total combined uncertainties of the measurements were assessed. The results show statistically significant reduction with age in both permittivity and conductivity of 10 out of 15 measured tissues. A...

journal_title：Physics in medicine and biology

authors： Peyman A,Gabriel C,Grant EH,Vermeeren G,Martens L

更新日期：2009-01-21 00:00:00

abstract：:In this study, the quantitative accuracy of different attenuation correction strategies presently available for the High Resolution Research Tomograph (HRRT) was investigated. These attenuation correction methods differ in reconstruction and processing (segmentation) algorithms used for generating a micro-image from m...

journal_title：Physics in medicine and biology

authors： van Velden FH,Kloet RW,van Berckel BN,Molthoff CF,de Jong HW,Lammertsma AA,Boellaard R

更新日期：2008-01-07 00:00:00

abstract：:The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were impl...

journal_title：Physics in medicine and biology

authors： Hornblower VD,Yu E,Fenster A,Battista JJ,Malthaner RA

更新日期：2007-01-07 00:00:00

abstract：:Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

journal_title：Physics in medicine and biology

authors： Buettner F,Gulliford SL,Webb S,Partridge M

更新日期：2011-04-07 00:00:00

abstract：:Uncemented prosthetic joint implants used in orthopaedic surgery are usually coated with a porous surface to encourage bone ingrowth. Better contact between the endosteal bone and the porous surface improves ingrowth, and such contact may be increased if the joint further subsides into position in the first weeks foll...

journal_title：Physics in medicine and biology

authors： Berry E,Langkamer VG,Jackson PC,Snow M,Goddard PR,Wells PN

更新日期：1993-02-01 00:00:00

abstract：:This work investigated the differences between multileaf collimator (MLC) positioning accuracy determined using either log files or electronic portal imaging devices (EPID) and then assessed the possibility of reducing patient specific quality control (QC) via phantom-less methodologies. In-house software was develope...

journal_title：Physics in medicine and biology

authors： Agnew A,Agnew CE,Grattan MW,Hounsell AR,McGarry CK

更新日期：2014-05-07 00:00:00

abstract：:In the IAEA TRS-381 protocol, k(cel) and p(cel) account for the central electrode perturbation during the air kerma chamber calibration and the in-phantom measurements. The values of these correction factors are based mainly on Monte Carlo simulations. In the present work experimental data on k(cel) and p(cel) for the...

journal_title：Physics in medicine and biology

authors： Palm A,Mattsson O

更新日期：1999-05-01 00:00:00

abstract：:Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...

journal_title：Physics in medicine and biology

authors： Mignani AG,Baldini F

更新日期：1997-05-01 00:00:00

abstract：:Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and ap...

journal_title：Physics in medicine and biology

authors： Carlsson GA,Carlsson CA,Nielsen B,Persliden J

更新日期：1986-07-01 00:00:00

abstract：:A method was developed to quantify the intensity of tissue staining using a CCD (charge-coupled device) camera. Reflection spectra of NBT-stained (nitro-blue tetrazolium-stained) and unstained myocardium were recorded via fibre optics coupled to a CCD camera, connected to a microcomputer. The calculation of the intens...

journal_title：Physics in medicine and biology

authors： Schröder T,Koch G,Schnabel PA,Hering JP,Bretschneider HJ,Richter J,Hellige G

更新日期：1991-06-01 00:00:00

abstract：:The phosphor GdO2S:Tb is widely used in camera-based electronic portal imaging devices (EPIDs). There is considerable interest in the application of EPIDs to dosimetry and the verification of intensity modulated radiation therapy produced by dynamic multileaf collimation (DMLC). This paper presents direct measurement ...

journal_title：Physics in medicine and biology

authors： Glendinning AG,Hunt SG,Bonnett DE

更新日期：2001-02-01 00:00:00

abstract：:We describe an improved algorithm for localising equivalent sources of biomagnetic fields in the human brain. The algorithm is an improvement over the sphere model in that it considers two distinct surfaces: an ellipsoid, to model the region of the skull on which the sensors are placed, and a sphere as the medium in w...

journal_title：Physics in medicine and biology

authors： Pistella F,Barone P,Narici L,Ocello N,Pizzella V,Romani GL

更新日期：1987-01-01 00:00:00

abstract：:Compromises in the design of a positron emission tomography (PET) insert for a magnetic resonance imaging (MRI) system should minimize the deterioration of image quality in both modalities, particularly when simultaneous demanding acquisitions are performed. In this work, the advantages of using individually read-out ...

journal_title：Physics in medicine and biology

authors： Omidvari N,Topping G,Cabello J,Paul S,Schwaiger M,Ziegler SI

更新日期：2018-05-01 00:00:00

abstract：:The purpose of this study was to evaluate the impact of numerical errors caused by the floating point representation of real numbers in a GPU-based Monte Carlo code used for dose calculation in radiation oncology, and to identify situations where this type of error arises. The program used as a benchmark was bGPUMCD. ...

journal_title：Physics in medicine and biology

authors： Magnoux V,Ozell B,Bonenfant É,Després P

更新日期：2015-07-07 00:00:00

abstract：:The silicon photomultiplier (Si-PM) is a promising photo-detector for PET for use in magnetic resonance imaging (MRI) systems because it has high gain and is insensitive to static magnetic fields. Recently we developed a Si-PM-based depth-of-interaction PET system for small animals and performed simultaneous measureme...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Watabe T,Watabe H,Aoki M,Sugiyama E,Imaizumi M,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2012-01-21 00:00:00

abstract：:For conventional irradiation devices, the radiation isocenter accuracy is determined by star shot measurements on films. In magnetic resonance (MR)-guided radiotherapy devices, the results of this test may be altered by the magnetic field and the need to align the radiation and imaging isocenter may require a modifica...

journal_title：Physics in medicine and biology

authors： Dorsch S,Mann P,Lang C,Haering P,Runz A,Karger CP

更新日期：2018-05-29 00:00:00

abstract：:This study aims to build a feasible mathematical model to analyze the mass evolution of NSCLC during standard fractionated radiotherapy. Seventy-three cases of NSCLC who were received radiotherapy with prescription dose of 2 Gy  ×  30 fx were selected retrospectively and divided into adenocarcinoma (ADC) group and squ...

journal_title：Physics in medicine and biology

authors： Chen J,Wang K,Jian J,Zhang W

更新日期：2019-11-26 00:00:00

abstract：:Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Sim...

journal_title：Physics in medicine and biology

authors： Torres-Espallardo I,Rafecas M,Spanoudaki V,McElroy DP,Ziegler SI

更新日期：2008-05-07 00:00:00

abstract：:The goals of this study were (1) to characterize the optical artefacts affecting measurement accuracy in a volumetric liquid scintillator detector, and (2) to develop methods to correct for these artefacts. The optical artefacts addressed were photon scattering, refraction, camera perspective, vignetting, lens distort...

journal_title：Physics in medicine and biology

authors： Robertson D,Hui C,Archambault L,Mohan R,Beddar S

更新日期：2014-01-06 00:00:00