Risk of venous thromboembolism in patients with inflammatory bowel disease.


:There is ample evidence of an increased risk of venous thromboembolism (VTE) in inflammatory bowel disease (IBD). Recent large studies have quantified this risk showing that IBD patients run a 1.5 to 3.6 higher risk of developing VTE than healthy controls. The development of VTE in IBD seems to be multifactorial, resulting from multiple interactions between acquired and inherited risk factors. The most important independent acquired risk factors include disease activity, hospitalization, colonic localization, and recent surgery. The main genetic defects that have been established as risk factors for VTE in the general population are rather uncommon in IBD, but when present, they increase the risk of VTE. IBD has been demonstrated to represent an independent risk factor for the recurrence of VTE. An increased risk of VTE-related mortality when compared with non-IBD patients has been reported. The guidelines for diagnosis and treatment of IBD patients with VTE are similar to that of thrombotic non-IBD patients. There is a consensus on the use of thromboprophylaxis mainly in hospitalized IBD patients with acute flares, but the prevention strategies need further evaluation in future studies.


Semin Thromb Hemost


Koutroumpakis EI,Tsiolakidou G,Koutroubakis IE




Has Abstract


2013-07-01 00:00:00












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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Davies PF,Civelek M,Fang Y,Guerraty MA,Passerini AG

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    journal_title:Seminars in thrombosis and hemostasis

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    journal_title:Seminars in thrombosis and hemostasis

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    更新日期:2010-06-01 00:00:00

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    authors: Turner N,Nolasco L,Nolasco J,Sartain S,Moake J

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Dempfle CE

    更新日期:2000-01-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


    authors: Morillo R,Moores L,Jiménez D

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Rodriguez-Merchan EC

    更新日期:2003-02-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

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    authors: Pengo V

    更新日期:2006-11-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Lorenz R,Olbert P,Born P

    更新日期:1996-01-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Levi M,de Peuter OR,Kamphuisen PW

    更新日期:2009-09-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2015-04-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Fareed J,Walenga JM,Williamson K,Emanuele RM,Kumar A,Hoppensteadt DA

    更新日期:1985-01-01 00:00:00

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    journal_title:Seminars in thrombosis and hemostasis

    pub_type: 杂志文章,评审


    authors: Casu B,Naggi A,Torri G

    更新日期:2002-08-01 00:00:00