Evaluation of the leishmanicidal and cytotoxic potential of essential oils derived from ten colombian plants.

Abstract:

BACKGROUND:The leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. METHODS:Essential oils were obtained by the steam distillation of plant leaves without any prior processing. Cytotoxicity was tested on J774 macrophages and leishmanicidal activity was assessed against four species of Leishmania associated with cutaneous leishmaniasis. RESULTS:Seven essential oils exhibited activity against Leishmania parasites, five of which were toxic against J774 macrophages. Selectivity indices of >6 and 13 were calculated for the essential oils of Ocimum basilicum and Origanum vulgare, respectively. CONCLUSION:The essential oil of Ocimum basilicum was active against promastigotes of Leishmania and innocuous to J774 macrophages at concentrations up to 1600 µg/mL and should be further investigated for leishmanicidal activity in others in vitro and in vivo experimental models.

journal_name

Iran J Parasitol

authors

Sanchez-Suarez J,Riveros I,Delgado G

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

129-36

issue

1

eissn

1735-7020

issn

2008-238X

journal_volume

8

pub_type

杂志文章
  • Kinetics Evaluation of IgM and IgG Levels in the Mice Infected with Trichinella spiralis Experimentally Using ES Antigens from Different Developmental Stages of the Parasite.

    abstract:Background:To assay the Trichinella-specific IgM and IgG antibody responses during the early stage of infection, serum was collected from mice infected with the muscle larvae (ML) of T. spiralis (ISS534) at different dpi (days post infection) up to 60 days. Methods:The levels of IgM and IgG antibodies in serum were me...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Zhai CC,Sun ZJ,Liu MY,Liu XL,Bai X,Wang XL,Wu XP,Chen JX

    更新日期:2019-04-01 00:00:00

  • Seroprevalence of Toxoplasma gondii in Pregnant Women and Bioassay of IgM Positive Cases in Zanjan, Northwest of Iran.

    abstract:BACKGROUND:The aim of this study was to determine the Toxoplasma antibodies in pregnant women in Zanjan, by ELISA method. METHODS:Blood samples were taken from 500 pregnant women referred to the health centers of Zanjan City, North West Iran, IgM and IgG titers were primarily evaluated. The collected data were analyze...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Hajsoleimani F,Ataeian A,Nourian A,Mazloomzadeh S

    更新日期:2012-01-01 00:00:00

  • Prevalence of Intestinal Parasites among Rural Residents of Takestan in North-West of Iran.

    abstract:Background:Intestinal parasites are one of the health challenges in developing countries. Decreasing the prevalence of intestinal parasitic infections (IPIs) is one of the main aims of health services in these countries. This study was designed to determine the current status of IPIs in rural residents of Takestan a to...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Taherkhani K,Barikani A,Shahnazi M,Saraei M

    更新日期:2019-10-01 00:00:00

  • Investigation of Double-Band Electrophoretic Pattern of ITS-rDNA Region in Iranian Isolates of Leishmania tropica.

    abstract:BACKGROUND:Leishmania tropica is a genetically divergent species. Amplification of entire internal transcribed spacer (ITS) region of L. tropica isolates obtained from Bam district, one of the well known focus of anthroponotic cutaneous leishmaniasis (ACL) in Iran, revealed a double-band pattern in agarose gel electrop...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Ghatee M,Sharifi I,Mirhendi H,Kanannejad Z,Hatam G

    更新日期:2013-04-01 00:00:00

  • Assessment of Recombinant A2-Latex Agglutination Test (RA2-LAT) and RA2-ELISA for Detection of Canine Visceral Leishmaniasis: A Comparative Field Study with Direct Agglutination Test in Northwestern Iran.

    abstract:Background:This study aimed to set-up latex agglutination test (LAT) and ELISA based on recombinant A2 from Iranian strain of Leishmania (L.) infantum (rA2-Ag) and evaluated for detection of anti-Leishmania antibodies in dogs compared to standard direct agglutination test (DAT). Methods:The rA2-Ag was synthesized unde...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Farahmand M,Nahrevanian H,Khalaj V,Mohebali M,Barati M,Naderi S,Zarei Z,Khalili G

    更新日期:2018-04-01 00:00:00

  • Detection of Potentially Diagnostic Leishmania Antigens with Western Blot Analysis of Sera from Patients with Cutaneous and Visceral Leishmaniases.

    abstract:BACKGROUND:Visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) are important public health problems in Iran. We aimed to evaluate the diagnostic potential of Western blot (WB) compared with indirect immunofluorescence test (IFAT) to serodiagnosis of leishmaniasis. METHODS:This study was performed from 2010-20...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Seyyedtabaei SJ,Rostami A,Haghighi A,Mohebali M,Kazemi B,Fallahi S,Spotin A

    更新日期:2017-04-01 00:00:00

  • Designing a Recombinant Multi-Epitope Antigen of Echinococcus granulosus to Diagnose Human Cystic Echinococcosis.

    abstract:Background:Cystic echinococcosis can cause severe disease and probable death in humans. Epitopes of its antigens play a key role in the sensitivity and specificity of immunodiagnostic tests. Methods:Epitope prediction software programs predict the most antigenic linear B-cell epitopes of AgB (8 kD), Ag5, and Ag95. Six...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Mirzapour A,Seyyed Tabaei SJ,Bandehpour M,Haghighi A,Kazemi B

    更新日期:2020-01-01 00:00:00

  • Protection Efficacy of Multivalent Egg Yolk Immunoglobulin against Eimeria tenella Infection in Chickens.

    abstract:BACKGROUND:To control avian coccidiosis with drug-independent strategy effectively and safely, multivalent hyperimmune egg yolk immunoglobulin (IgY) was prepared and its ability to protect against Eimeria tenella infection was evaluated. METHODS:Hens were orally immunized with live oocysts of 5 species of Eimeria for ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Xu J,Ren C,Wang S,Liu D,Cao L,Tao J

    更新日期:2013-07-01 00:00:00

  • Evaluation of Immunogenicity of Novel Isoform of EG95 (EG95-5G1) From Echinococcus granulosus in BALB/C Mice.

    abstract:BACKGROUND:Echinococcosis is a zoonotic parasitic disease of humans and various herbivorous domestic animals transmitted by the contact with domestic and wild carnivores, mainly dogs and foxes. The aim of this study is the production, purification and evaluation immunogenicity of new construction of EG95 protein. METH...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Pirestani M,Dalimi A,Sarvi S,Khoramabadi N

    更新日期:2014-10-01 00:00:00

  • Molecular Evaluation of a Case of Visceral Leishmaniasis Due to Leishmania tropica in Southwestern Iran.

    abstract::We describe a case of visceral leishmaniasis (VL) due to Leishmania tropica in a 50-year-old Iranian man lived in a VL-endemic area in southwest of Iran. The patient presented with a 3-month history of fever and splenomegaly. Clinical signs and serological findings were suggestive of VL. Spleen biopsy was taken from t...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Sarkari B,Bavarsad Ahmadpour N,Moshfe A,Hajjaran H

    更新日期:2016-01-01 00:00:00

  • Molecular characterization of eimeria species naturally infecting egyptian baldi chickens.

    abstract:BACKGROUND:Coccidiosis is a serious protozoal disease of poultry. The identification of Eimeria species has important implications for diagnosis and control as well as for epidemiology. The molecular characterization of Eimeria species infecting Egyptian baladi chickens was investigated. METHODS:Eimeria species oocyst...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Gadelhaq SM,Arafa WM,Aboelhadid SM

    更新日期:2015-01-01 00:00:00

  • An incidental diagnosis of neurocysticercosis in a dental patient.

    abstract::Tenia solium, a parasite causes cysticercous cellulose when affecting the central nervous system, the manifestation is called neurocysticercosis. The most common symptom in neurocysticercosis is seizure. Generally, oral diagnosticians come across cases of oral cysticercosis and it is rare to find a case of neurocystic...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Puttaraju MK,Hanasoge Srivathsa S

    更新日期:2013-10-01 00:00:00

  • Determination of Asymptomatic Malaria among Afghani and Pakistani Immigrants and Native Population in South of Kerman Province, Iran.

    abstract:BACKGROUND:This study was proposed to monitor the situation of asymptomatic malaria among the native population and Afghani and Pakistani immigrants in Kahnooj and Ghale-Ganj districts from Kerman Province, Southeastern Iran. METHODS:A number of 180 and 120 individuals from Kahnooj and Ghale-Ganj respectively were reg...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Amirshekari MB,Nateghpour M,Raeisi A,Motevalli Haghi A,Farivar L,Edrissian G

    更新日期:2016-04-01 00:00:00

  • Detection and Molecular Characterization of Cryptosporidium species in Recreational Waters of Chaharmahal va Bakhtiyari Province of Iran using nested-PCR-RFLP.

    abstract:BACKGROUND:The aim of this study was to detect and characterize Cryptosporidium spp. in water samples collected from recreational ponds of Chaharmahal va Bakhtiyari Province of Iran. METHODS:Thirty water samples were collected from November 2009 to May 2010. Each sample contained 10 liters of water. We used the SSU rR...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Manouchehri Naeini K,Asadi M,Hashemzade Chaleshtori M

    更新日期:2011-03-01 00:00:00

  • In vivo Susceptibility of Plasmodium vivax to Chloroquine in Southeastern Iran.

    abstract:BACKGROUND:Plasmodium vivax is the predominant species causes of malaria with about 90% total annual reported malaria in Iran. This study conducted to determine the susceptibility of Plasmodium vivax isolates to chloroquine in Sistan and Balochistan Province, southeastern Iran. METHODS:A total 270 subjects with sympto...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Heidari A,Keshavarz H,Shojaee S,Raeisi A,Dittrich S

    更新日期:2012-01-01 00:00:00

  • The Anti-leishmanial Efficacy of Artemisia dracunculus Ethanolic Extract in Vitro and Its Effects on IFN-γ and IL-4 Response.

    abstract:BACKGROUND:Leishmaniasis is a parasitic disease that appears with a range of symptoms including cutaneous, mucocutaneous, and visceral leishmaniasis. The present study sought to determine the antileishmanial effect of the extract of Artemisia dracunculus (Tarragon) compared to control treatment with pentavalent antimon...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Rezaei R,Hazrati Tappeh K,Seyyedi S,Mikaili P

    更新日期:2017-07-01 00:00:00

  • Malaria Vaccine Development: The Need for Novel Approaches: A Review Article.

    abstract:Background:Although rigorous efforts have substantially decreased the malaria burden through decades, it still threatens the lives of millions of children. Development of an effective vaccine can provide important approach in malaria control strategies. Unfortunately, development of an effective vaccine for falciparum ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章,评审

    doi:

    authors: Mahmoudi S,Keshavarz H

    更新日期:2018-01-01 00:00:00

  • Biopathologic Characterization of Three Mixed Poultry Eimeria spp. Isolates.

    abstract:BACKGROUND:Coccidiosis of domestic fowl, caused by species of the Genus Eimeria, is responsible for important economic losses in poultry production. Because different species and/or strains can vary in pathogenicity and other biological parameters, their precise characterization is important for epizootiological studie...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Arabkhazaeli F,Nabian S,Modirsaneii M,Mansoori B,Rahbari S

    更新日期:2011-12-01 00:00:00

  • The Effect of Garlic Extract on Expression of INFγ And Inos Genes in Macrophages Infected with Leishmania major.

    abstract:BACKGROUND:The study was aimed to show the effect of molecular mechanism of Aqueous Garlic Extract (AGE) on expression of IFNγ and iNOS genes in Leishmania major. METHODS:Leishmania major promastigotes (MRHO/IR/75/ER) were added to the in-vitro cultured J774 cell line, the cells were incubated for 72 hours. Various co...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Gharavi M,Nobakht M,Khademvatan Sh,Bandani E,Bakhshayesh M,Roozbehani M

    更新日期:2011-08-01 00:00:00

  • Comparison between Combination Therapy of Oral Terbinafine and Cryotherapy versus Systemic Meglumine Antimoniate and Cryotherapy in Cutaneous Leishmaniasis: A Randomized Clinical Trial.

    abstract:BACKGROUND:Leishmaniasis is a parasitic infection that may lead to a variety of manifestations. In Iran, cutaneous leishmaniasis (CL) has a high prevalence. There are many treatment modalities for CL. The use of oral terbinafine in the treatment of CL has recently been considered. The aim of this study was to compare c...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Farajzadeh S,Esfandiarpour I,Haghdoost AA,Mohammadi S,Mohebbi A,Mohebbi E,Mostafavi M

    更新日期:2015-01-01 00:00:00

  • Microscopy and serological assessment for heartworm infection in cats in makati, Philippines showing clinical signs of dirofilariosis.

    abstract:BACKGROUND:The sole published data on feline heartworm infection in the Philippines was reported four decades ago. The study therefore endeavoured to assess and provide an update on the current status of heartworm infection in domesticated feline species using serologic and parasitological examination methods. METHODS...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Baticados A,Baticados W,Coz G,Carlos S,Carlos E

    更新日期:2013-01-01 00:00:00

  • Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens.

    abstract:Background:Whole killed Leishmania vaccine reached phase III clinical trials but failed to display significant efficacy in human mainly due to limited Th1 inducer adjuvant. Liposomes consisting of 1, 2-dioleoyl-3trimethylammonium-propane (DOTAP) bearing an inherent adjuvanticity and 1, 2-dioleoyl-L-α-glycero-3-phosphat...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Hojatizade M,Badiee A,Khamesipour A,Jaafari MR

    更新日期:2019-01-01 00:00:00

  • Benzimidazole -Resistance in Haemonchus contortus: New PCR-RFLP Method for the Detection of Point Mutation at Codon 167 of Isotype 1 β-Tubulin Gene.

    abstract:BACKGROUND:Due to the lack of a suitable and economic test for the analysis of the polymorphism at codon 167, we developed a new PCR-RFLP technique, based on a modified forward primer (UT-HC167 MF-primer), to identify simultaneously the SNPs at codons 167 and 200 of isotype 1 β-tubulin gene of Haemonchus contortus. ME...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Shokrani H,Shayan P,Eslami A,Nabavi R

    更新日期:2012-01-01 00:00:00

  • Disseminated Leishmaniasis Due to Using Immunosuppression Drugs: A Case Report.

    abstract::Visceral leishmaniasis is a common parasitic disease between humans and animals, transmitted by sandflies (Phlebotomus) in the Mediterranean countries, including Iran. The statistics have been reported less than real due to errors in the diagnosis and reporting of affected cases. In this report, we will present the sy...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Afshoon M,Abdolsalehi M,Alinia G,Borhani K,Yaghmaie B,Khodabandeh M

    更新日期:2020-04-01 00:00:00

  • PCR-RFLP Analysis of 28 SrDNA for Specification of Fasciola gigantica (Cobbold, 1855) in the Infected Lymnaea auricularia (Linnaeus, 1785) Snails from Northwestern Iran.

    abstract:BACKGROUND:Fasciolosis in livestock is a crucial concern in the globe, mainly due to its impact on human health. The aim of this study was to determine the rate of infection with Fasciola gigantica (Cobbold, 1855) larvae in the field-collected snails of Lymnaea auricularia (Linnaeus, 1785) from northwestern Iran using ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Yakhchali M,Malekzadeh-Viayeh R,Imani-Baran A

    更新日期:2014-09-01 00:00:00

  • Genotype Characteristics of Giardia duodenalis in Patients Using High Resolution Melting Analysis Technique in Khorramabad, Iran.

    abstract:Background:We aimed at genotyping and evaluating the predominance of G. duodenalis assemblages isolated from patients referred to medical laboratories in Khorramabad, Iran from Nov 2015 to Sep 2016. Hence, the development of a cost-effective HRM approach to determine genotypes of G. duodenalis based on the triosephosph...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Sepahvand A,Hosseini-Safa A,Yousofi HA,Tajedini MH,Pahlavan Gharehbabah R,Pestehchian N

    更新日期:2020-04-01 00:00:00

  • Development and Assessment of Loop-Mediated Isothermal Amplification (LAMP) Assay for the Diagnosis of Human Visceral Leishmaniasis in Iran.

    abstract:BACKGROUND:Parasitological methods for the diagnosis of Visceral leishmaniasis (VL) require invasive procedures, so serological and molecular approaches have been developed but are not generally applicable in the field. We evaluated a loop mediated isothermal amplification (LAMP) assay using blood from VL patients and ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Ghasemian M,Gharavi MJ,Akhlaghi L,Mohebali M,Meamar AR,Aryan E,Oormazdi H

    更新日期:2014-03-01 00:00:00

  • Allelic Variations of Plasmodium vivax Apical Membrane Antigen-1 (Pv AMA-1) in Malarious Areas of Southeastern Iran Using PCR-RFLP Technique.

    abstract:Background:Although Plasmodium vivax is usually known as benign malaria, some variations of the parasite can result in acute and sever infection. In this study we tried to determine some genetic variations in PvAMA-1 antigen among the samples were collected form southeastern Iran. Methods:About two ml blood samples we...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Motevalli Haghi A,Moradi S,Nateghpour M,Edrissian G

    更新日期:2018-07-01 00:00:00

  • The First Detection of Co-Infection of Double-Stranded RNA Virus 1, 2 and 3 in Iranian Isolates of Trichomonas vaginalis.

    abstract:Background:The Totiviridae family includes a number of double-stranded RNA viruses that can infect Trichomonas vaginalis. Some T. vaginalis isolates are infected with one or more double-stranded RNA (dsRNA) viruses. In this study, different strains of double-stranded RNA virus in Iranian isolates of T. vaginalis were e...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:10.18502/ijpa.v15i3.4200

    authors: Bokharaei-Salim F,Esteghamati A,Khanaliha K,Esghaei M,Donyavi T,Salemi B

    更新日期:2020-07-01 00:00:00

  • Zoonotic and Non-zoonotic Parasites of Wild Rodents in Turkman Sahra, Northeastern Iran.

    abstract:BACKGROUND:This study was conducted to collect informative data on the parasitic infection of wild rodents, emphasizing on finding parasites, which have medical importance to human. METHODS:During 2012-2014, a total number of 91 wild rodents were captured from rural areas of Turkmen Sahra, Golestan Province, using han...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Gholipoury M,Rezai HR,Namroodi S,Arab Khazaeli F

    更新日期:2016-07-01 00:00:00