Serum Pepsinogen Values in Japanese Junior High School Students With Reference to Helicobacter Pylori Infection.

Abstract:

BACKGROUND:Distributions of serum pepsinogen (PG) values were assessed in Helicobacter pylori-infected and non-infected junior high school students (aged 12-15 years) in Japan. METHODS:All junior high school students (1,225 in total) in Sasayama city, who were basically healthy, were asked to provide urine and serum samples, which were used to measure urine and serum H. pylori antibodies using ELISA kits and PG values. The subjects, whose urine and serum antibodies were both positive, were considered H. pylori infected. RESULTS:Of the 187 subjects who provided urine and blood samples, 8 were infected, 4 had discrepant results, 4 had negative serum antibody titers no less than 3.0 U/ml, and 171 were non-infected. In the H. pylori non-infected subjects, the median PG I and PG II values and PG I to PG II ratio (PG I/II) were 40.8 ng/mL, 9.5 ng/mL, and 4.4, respectively, whereas in the infected subjects, these values were 55.4 ng/mL, 17.0 ng/mL, and 3.3, respectively (each P < 0.01). In the non-infected subjects, PG I and PG II were significantly higher in males than in females (P < 0.01). CONCLUSIONS:The PG I and PG II values were higher, and the PG I/II was lower in H. pylori infected students than in non-infected students. In H. pylori non-infected students, males showed higher PG I and PG II values than females. The distributions of PG values in junior high school students differed from those in adults.

journal_name

J Epidemiol

journal_title

Journal of epidemiology

authors

Okuda M,Lin Y,Mabe K,Kato M,Osaki T,Miyamoto R,Okumura A,Kamiya S,Kikuchi S

doi

10.2188/jea.JE20180119

subject

Has Abstract

pub_date

2020-01-05 00:00:00

pages

30-36

issue

1

eissn

0917-5040

issn

1349-9092

journal_volume

30

pub_type

杂志文章
  • Socioeconomic status, self-rated health, and mortality in a multiethnic sample of US adults.

    abstract:OBJECTIVE:To examine the association between socioeconomic status (SES), self-rated health (SRH), and mortality separately by race-ethnicity in a nationally representative sample of US adults. METHODS:We analyzed data from 16 716 adult women and men who were followed up for mortality for up to 12 years as part of the ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20100142

    authors: Suresh S,Sabanayagam C,Shankar A

    更新日期:2011-01-01 00:00:00

  • Relationship between coffee and green tea consumption and all-cause mortality in a cohort of a rural Japanese population.

    abstract::We conducted a cohort study to investigate the effects of coffee and green tea consumption on all-cause mortality in a rural Japanese population. Data were obtained from 2,855 men and women aged 40-79 years in 1989, and during the subsequent 9.9 years of follow-up. Using the Cox regression model to adjust for potentia...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.12.191

    authors: Iwai N,Ohshiro H,Kurozawa Y,Hosoda T,Morita H,Funakawa K,Okamoto M,Nose T

    更新日期:2002-05-01 00:00:00

  • Thigh circumference and diabetes: obesity as a potential effect modifier.

    abstract:BACKGROUND:Thigh circumference is associated with diabetes risk; however, the role of obesity as a potential effect modifier has not been well studied. METHODS:We examined the association between thigh circumference and diabetes in a cross-sectional study of 384 612 Koreans aged 30 to 79 years. The association between...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20120174

    authors: Jung KJ,Kimm H,Yun JE,Jee SH

    更新日期:2013-09-05 00:00:00

  • Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method.

    abstract::We examined apolipoprotein E (Apo E) polymorphism and methylenetetrahydrofolate reductase (MTHFR) 677 C to T mutation by using the polymerase chain reaction (PCR) method in 100 elderly Japanese aged 60 or more, and assessed whether these genetic factors are associated with an increased risk for the clinical phenotypes...

    journal_title:Journal of epidemiology

    pub_type: 临床试验,杂志文章

    doi:10.2188/jea.10.163

    authors: Nishiyama M,Kato Y,Hashimoto M,Yukawa S,Omori K

    更新日期:2000-05-01 00:00:00

  • Objectively-Assessed Patterns and Reported Domains of Sedentary Behavior Among Japanese Older Adults.

    abstract:BACKGROUND:Prolonged periods of sitting time can be adversely associated with older adults' well-being and functional capacities. Understanding patterns and contexts of sedentary behaviors (SB) can inform approaches to prevention. This study examined Japanese older adults' objectively-assessed patterns and reported dom...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20180041

    authors: Shibata A,Oka K,Ishii K,Miyawaki R,Inoue S,Sugiyama T,Owen N

    更新日期:2019-09-05 00:00:00

  • Profile of Non-communicable Disease Risk Factors Among Young People in Palau.

    abstract:BACKGROUND:Although non-communicable diseases (NCDs) have become the predominant health problems of Palauan society, there have been no comprehensive data on NCD risk factors available to develop effective control strategies. Therefore, the first Palauan national STEPwise approach to risk factor Surveillance (STEPS) wa...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20140156

    authors: Chiang C,Singeo ST Jr,Yatsuya H,Honjo K,Mita T,Ikerdeu E,Cui R,Li Y,Watson BM,Ngirmang G,Iso H,Aoyama A

    更新日期:2015-01-01 00:00:00

  • Assessing the effects of non-steroidal anti-inflammatory drugs on antihypertensive drug therapy using post-marketing surveillance database.

    abstract:BACKGROUND:Antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat many common diseases. However, it has been suspected that interactions between these drugs exist. Here, we assessed the interactions between non-selective NSAIDs and several classes of antihypertensive drugs. METHODS:The s...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je2007413

    authors: Ishiguro C,Fujita T,Omori T,Fujii Y,Mayama T,Sato T

    更新日期:2008-01-01 00:00:00

  • Changes in drug utilization after publication of clinical trials and drug-related scandals in Japan: an interrupted time series analysis, 2005-2017.

    abstract::BackgroundBreaches of ethics undermine the practice of medicine. In Japan, two major scandals involving clinical research and drug marketing occurred after the publication of clinical trials. To study the effects of those scandals, we evaluated changes in the use of first-generation angiotensin II receptor blockers (A...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20200181

    authors: Fukuma S,Ikenoue T,Yamada Y,Saito Y,Green J,Nakayama T,Fukuhara S

    更新日期:2020-07-04 00:00:00

  • Validity and reproducibility of a self-administered food frequency questionnaire used in the baseline survey of the JPHC Study Cohort I.

    abstract::We examined the validity and reproducibility of a 44-item food frequency questionnaire used in a baseline survey of the Japan Public Health Center-Based Prospective Study Cohort I conducted in February 1990. Subjects were 94 men and 107 women selected on a voluntary basis among respondents to the baseline survey. Four...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.2188/jea.13.1sup_125

    authors: Tsubono Y,Kobayashi M,Sasaki S,Tsugane S,JPHC.

    更新日期:2003-01-01 00:00:00

  • Life expectancy among Japanese of different smoking status in Japan: NIPPON DATA80.

    abstract:BACKGROUND:The life expectancy is an important measure for describing health status among population. Several studies from the United States and Europe showed the harm of smoking by describing the life expectancies with different smoking status. No such study is examined in Japan, the country with the world's highest l...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.17.31

    authors: Murakami Y,Ueshima H,Okamura T,Kadowaki T,Hozawa A,Kita Y,Hayakawa T,Okayama A,NIPPON DATA80 Research Group.

    更新日期:2007-03-01 00:00:00

  • Comparison of disease patterns and outcomes between non-Japanese and Japanese patients at a single tertiary emergency care center in Japan.

    abstract:BACKGROUND:Japan's historically low immigration rate and monolingual culture makes it a particularly interesting setting for clarifying non-national medical care. Our study objective was to examine disease patterns and outcome differences between Japanese and non-Japanese patients in a rapidly globalizing nation. METH...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20200211

    authors: Ishii E,Nawa N,Matsui H,Otomo Y,Fujiwara T

    更新日期:2020-12-05 00:00:00

  • A comparative epidemiological study of the effects of regular exercise on health level.

    abstract:STUDY OBJECT:To reveal the relationship between regular exercise and physical fitness, life style, mental health, and other cardiovascular risk factors among the Japanese. DESIGN:cross-sectional study. SUBJECTS:Three thousands, one hundred and thirty-two individuals (1,795 men and 1,336 women) over 40 years old who w...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.8.15

    authors: Hiraoka J,Ojima T,Nakamura Y,Yanagawa H

    更新日期:1998-03-01 00:00:00

  • The Relative Association of Collective Efficacy in School and Neighborhood Contexts With Adolescent Alcohol Use.

    abstract:BACKGROUND:It is unclear whether either neighborhood collective efficacy or school collective efficacy is associated with adolescent alcohol use. This study aimed to examine the relative contributions of collective efficacy, both in school and in the neighborhood contexts, to alcohol use among Japanese adolescents. ME...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20180125

    authors: Takakura M,Miyagi M,Ueji M,Kobayashi M,Kurihara A,Kyan A

    更新日期:2019-10-05 00:00:00

  • Physical activity and cardiovascular disease in Japan: the Jichi Medical School Cohort Study.

    abstract:BACKGROUND:Many studies have reported an association between physical activity and cardiovascular disease (CVD); however, the effect of physical activity remains controversial. Few such studies have been conducted in Japan. Therefore, we examined the relationship between physical activity and death from CVD using prosp...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20090051

    authors: Shibata Y,Hayasaka S,Yamada T,Goto Y,Ojima T,Ishikawa S,Kayaba K,Gotoh T,Nakamura Y

    更新日期:2010-01-01 00:00:00

  • Annual and weekly incidence rates of influenza and pediatric diseases estimated from infectious disease surveillance data in Japan, 2002-2005.

    abstract:BACKGROUND:The method for estimating incidence of infectious diseases from sentinel surveillance data has been proposed. In Japan, although the annual incidence rates of influenza and pediatric diseases estimated using the method were reported, their weekly incidence rates have not. METHODS:The weekly sex- and age-spe...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.17.s32

    authors: Kawado M,Hashimoto S,Murakami Y,Izumida M,Ohta A,Tada Y,Shigematsu M,Yasui Y,Taniguchi K,Nagai M

    更新日期:2007-12-01 00:00:00

  • Association between nocturnal breastfeeding and snacking habits and the risk of early childhood caries in 18- to 23-month-old Japanese children.

    abstract:BACKGROUND:Early childhood caries (ECC) is one of the most prevalent chronic diseases among children. The aim of this cross-sectional study was to investigate the association between nocturnal breastfeeding, snacking habits, or other risk factors and ECC in 18- to 23-month-old Japanese children. METHODS:Study subjects...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20140097

    authors: Nakayama Y,Mori M

    更新日期:2015-01-01 00:00:00

  • Effects of passive smoking on serum levels of carotenoids and alpha-tocopherol.

    abstract::To evaluate the effects of passive smoking identified by urine cotinine on serum carotenoids and alpha-tocopherol, we categorized 124 residents in a rural city of Japan into 4 groups by their urine cotinine/creatinine (Cot/Cr) ratio (u.d. (undetectable); low (0-50 ng/mg); moderate (50-120 ng/mg); high (> 120 ng/mg)) a...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.8.146

    authors: Takatsuka N,Kawakami N,Ito Y,Kabuto M,Shimizu H

    更新日期:1998-08-01 00:00:00

  • Macronutrient Intake and Socioeconomic Status: NIPPON DATA2010.

    abstract:BACKGROUND:This study examined the relationships among household income, other SES indicators, and macronutrient intake in a cross-sectional study of a representative Japanese population. METHODS:In 2010, we established a cohort of participants in the National Health and Nutrition Survey (NHNS) from 300 randomly selec...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20170250

    authors: Sakurai M,Nakagawa H,Kadota A,Yoshita K,Nakamura Y,Okuda N,Nishi N,Miyamoto Y,Arima H,Ohkubo T,Okamura T,Ueshima H,Okayama A,Miura K

    更新日期:2018-01-01 00:00:00

  • Measuring effort-reward imbalance in school settings: a novel approach and its association with self-rated health.

    abstract:BACKGROUND:We attempted to apply the model of effort-reward imbalance (ERI) to school settings in order to measure students' psychosocial stress and analyze its association with self-rated health in adolescents. METHODS:A cross-sectional survey was conducted in Kunming, China among 1004 Chinese students (468 boys and ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20090057

    authors: Li J,Shang L,Wang T,Siegrist J

    更新日期:2010-01-01 00:00:00

  • Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the Tehran Lipid and Glucose Study.

    abstract:OBJECTIVE:To examine the validity and reproducibility of food groups in the semi-quantitative food frequency questionnaire (FFQ) developed for the Tehran Lipid and Glucose Study (TLGS). METHODS:To evaluate the reproducibility of food groups included in the FFQ, 132 subjects (61 men and 71 women) aged 20 years or older...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20090083

    authors: Esfahani FH,Asghari G,Mirmiran P,Azizi F

    更新日期:2010-01-01 00:00:00

  • Pathophysiologic mechanisms of obesity and related metabolic disorders: an epidemiologic study using questionnaire and serologic biomarkers.

    abstract:BACKGROUND:It is still unclear whether individuals with the same degree of obesity but different weight histories since young adulthood have different insulin concentration, prevalence of metabolic syndrome components and their clustering. METHODS:A cross-sectional study was conducted on 3,399 (for weight difference a...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.17.141

    authors: Yatsuya H

    更新日期:2007-09-01 00:00:00

  • Association of serum carotenoid levels with N-terminal pro-brain-type natriuretic peptide: a cross-sectional study in Japan.

    abstract:BACKGROUND:Several epidemiologic studies have reported an inverse association between serum levels of carotenoids and cardiovascular disease risk. However, no studies have reported an association between serum carotenoids and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in the general population. METHODS:...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20120087

    authors: Suzuki K,Ishii J,Kitagawa F,Kuno A,Kusuhara Y,Ochiai J,Ichino N,Osakabe K,Sugimoto K,Yamada H,Ito Y,Hamajima N,Inoue T

    更新日期:2013-01-01 00:00:00

  • Comparison of Intentional and Unintentional Injuries Among Chinese Children and Adolescents.

    abstract:BACKGROUND:The patterns and risk factors of intentional injuries compared to unintentional injuries among Chinese children and adolescents have not been examined in depth. This work comprehensively describes patterns of intentional injuries in China, for which little information has been previously published. METHODS:...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20190152

    authors: Yin X,Li D,Zhu K,Liang X,Peng S,Tan A,Du Y

    更新日期:2020-12-05 00:00:00

  • Association of school absence with air pollution in areas around arterial roads.

    abstract::Association of school absence with air pollution from suspended particulate matter (SPM) and nitrogen dioxide was analyzed in areas around arterial roads for five years, from 1993 to 1997. The prevalence of absence was calculated using the data for school absence in two schools around arterial roads, one of which is n...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.10.292

    authors: Makino K

    更新日期:2000-09-01 00:00:00

  • Accuracy of Death Certificates and Assessment of Factors for Misclassification of Underlying Cause of Death.

    abstract:BACKGROUND:Cause of death (COD) information taken from death certificates is often inaccurate and incomplete. However, the accuracy of Underlying CODs (UCODs) recorded on death certificates has not been comprehensively described when multiple diseases are present. METHODS:A total of 450 consecutive autopsies performed...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20150010

    authors: Mieno MN,Tanaka N,Arai T,Kawahara T,Kuchiba A,Ishikawa S,Sawabe M

    更新日期:2016-01-01 00:00:00

  • Covariation of cigarette smoking and other health-risk behaviors among Japanese high school students: a preliminary study.

    abstract::This study aims to determine if cigarette smoking is associated with engaging in other health-risk behaviors among high school students in Japan. Self-administered anonymous questionnaires were conducted in 1999 using a sample of 1,466 students (male: 50.5%, female: 49.5%) in grades 10 through 12 at seven public senio...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.11.224

    authors: Takakura M,Ueji M,Sakihara S

    更新日期:2001-09-01 00:00:00

  • Association of inflammatory gene polymorphisms and conventional risk factors with arterial stiffness by age.

    abstract:BACKGROUND:Inflammatory gene polymorphisms are potentially associated with atherosclerosis risk, but their age-related effects are unclear. To investigate the age-related effects of inflammatory gene polymorphisms on arterial stiffness, we conducted cross-sectional and 5-year follow-up studies using the cardio-ankle va...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20130054

    authors: Kheradmand M,Niimura H,Kuwabara K,Nakahata N,Nakamura A,Ogawa S,Mantjoro EM,Shimatani K,Nerome Y,Owaki T,Kusano K,Takezaki T

    更新日期:2013-01-01 00:00:00

  • The profiles of Kawasaki disease in China.

    abstract::Kawasaki disease in China was described for the first time in 1976 in Taiwan, and in 1978 in mainland, respectively. Questionnaire surveys had been conducted in both of the area of China and showed that the Kawasaki disease patients increased year by year. No data on incidence rates were available for these surveys be...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.11.103

    authors: Zhang T,Yanagawa H,Nakamura Y

    更新日期:2001-05-01 00:00:00

  • Relation of Helicobacter pylori infection and lifestyle to the risk of chronic atrophic gastritis: a cross-sectional study in Japan.

    abstract::To examine the mutual association of risk factors for both Helicobacter pylori (H. pylori) infection and chronic atrophic gastritis (CAG), a cross-sectional study on 954 residents of a rural town in Japan was conducted. Using an unconditional logistic model, we calculated the odds ratios (ORs) for H. pylori infection ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.12.105

    authors: Shibata K,Moriyama M,Fukushima T,Une H,Miyazaki M,Yamaguchi N

    更新日期:2002-03-01 00:00:00

  • Progress in Aging Epidemiology in Japan: The JAGES Project.

    abstract::Aging is a prominent topic in global health. The purpose of this report is to document progress in two of our research projects in Japan, which currently is the most aged society in the world. The Japan Gerontological Evaluation Study (JAGES) is one of the largest nation-wide research projects on aging, with more than...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20160093

    authors: Kondo K

    更新日期:2016-07-05 00:00:00