Abstract：
:Ingestion of bioactive compounds, such as hesperidin and naringin, found in citrus fruits and orange juice, can improve the homeostasis of gut microbiota. A controlled clinical study with temporal series intergroup design with 10 apparently healthy women (28.5 ± 8.4 years, 24.1 ± 3.3 kg/m2) were evaluated after continuous consumption of commercial pasteurized orange juice for 2 months. Samples of blood serum and stool were collected at basal time and periodically during the experiment for biochemical and microbiology assays. Intestinal microbiota was evaluated for total anaerobic bacteria, Lactobacillus spp., Bifidobacterium spp., and Clostridium spp. An independent culture evaluation was performed using Denaturing Gradient Gel Electrophoresis (DGGE). The pH, ammonium (NH4+), and short-chain fatty acids (SCFAs) were evaluated for microbial metabolism. The results showed that daily intake of orange juice did not change women's body composition, but improved blood biochemical parameters, such as low-density lipoprotein-cholesterol, glucose, and insulin sensitivity. Orange juice positively modulated the composition and metabolic activity of microbiota, increasing the population of fecal Bifidobacterium spp. and lactobacillus spp. Polymerase chain reaction-DGGE of microbiota showed similar composition of total bacteria, and microbial metabolism showed a reduction of ammonia and an increase of the production of SCFAs. These results suggested that a daily consumption of orange had a positive effect on the intestinal microbiota and metabolic biomarkers of young women, which may be an effective alternative for a healthy drink.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Lima ACD,Cecatti C,Fidélix MP,Adorno MAT,Sakamoto IK,Cesar TB,Sivieri Kdoi
10.1089/jmf.2018.0080subject
Has Abstractpub_date
2019-02-01 00:00:00pages
202-210issue
2eissn
1096-620Xissn
1557-7600journal_volume
22pub_type
杂志文章abstract：:We examined the effects of Rhizoma Dioscoreae Tokoronis extracts (RDTEs) on plasma lipids, body weight, and lipogenic enzymes. Mice were administered a standard chow diet, a 60% high-fat diet, or a high-fat diet with RDTE. Mice that were fed a high-fat diet containing RDTE were found to have lower increases in body an...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2008.1010
更新日期：2009-04-01 00:00:00
abstract：:Antimicrobial activities of 10-100% (wt/vol) concentrations of new honey, stored honey, heated honey, ultraviolet-exposed honey, and heated stored honey were tested against common human pathogens, including Escherichia coli, Entrobacter cloacae, Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella sp., Haemophilus...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/1096620041224139
更新日期：2004-07-01 00:00:00
abstract：:In traditional Korean medicine, lotus (Nelumbo nucifera Gaertn) roots have been used as an antidiabetic and an antiproliferative remedy. However, scientific publications on lotus properties are very limited. Therefore, it was decided to investigate the Korean white lotus cultivars in order to find out their bioactivit...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.0018
更新日期：2009-10-01 00:00:00
abstract：:Problems associated with current treatment regimens have generated a considerable interest in alternative approaches for the eradication of Helicobacter pylori infections using phytochemical compounds. In an attempt to identify potential sources of such compounds, the antimicrobial activity of five solvent extracts of...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2010.0127
更新日期：2011-07-01 00:00:00
abstract：:For many years mushrooms have been used empirically in traditional medicine to treat several diseases. Study of the maitake mushroom, with its immunomodulatory and antitumoral properties, has led to the isolation of several bioactive compounds. One of these, D fraction, is known to reduce tumor cell viability. This st...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2010.0095
更新日期：2011-06-01 00:00:00
abstract：:This study was designed to investigate the anti-obesity and anti-atherosclerotic effects of supplementation with Chungkookjang (CKJ), a traditional fermented soybean food, in overweight/obese subjects. The study was a 12-week, randomized, double-blind, placebo-controlled clinical trial followed by a 3-week screening p...
journal_title：Journal of medicinal food
pub_type： 杂志文章,随机对照试验
doi：10.1089/jmf.2010.1199
更新日期：2011-05-01 00:00:00
abstract：:Polyphenols and particularly flavonoids are well known in vitro antioxidants. Their consumption in foods has been shown to decrease the risk of heart disease in epidemiological studies. Because flavonoids are consumed with vitamin C in the diet, the combination may prove to be more beneficial than either alone. The co...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/10966200152744454
更新日期：2001-01-01 00:00:00
abstract：:Metabolic diseases, such as glucose intolerance and nonalcoholic fatty-liver disease (NAFLD), are primary risk factors for life-threatening conditions such as diabetes, heart attack, stroke, and hepatic cancer. Extracts from the tropical tree Moringa oleifera show antidiabetic, antioxidant, anti-inflammatory, and anti...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2016.3860
更新日期：2017-05-01 00:00:00
abstract：:Polyphenols, including green tea catechins, are secondary plant compounds often discussed in the context of health-promoting potential. Evidence for such effects is mainly derived from epidemiological and cell culture studies. The aim of the present study was to investigate antidiabetic, antiadipogenic, and anti-infla...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.0205
更新日期：2013-04-01 00:00:00
abstract：:Garlic has been used medicinally throughout human history. Allicin is considered the most therapeutic constituent of garlic. This study tested the antimicrobial activity of garlic allicin on oral pathogens associated with dental caries and periodontitis. Allicin was found effective against all the tested bacteria. The...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2010.0165
更新日期：2011-11-01 00:00:00
abstract：:Essential oil preparation of the terpenic type was introduced for the first time in the 1930s for the management of urolithiasis. Although essential oil preparations are registered in 50 countries, including some developed countries such as the United Kingdom, Italy, and Japan, for use in urolithiasis, no literature h...
journal_title：Journal of medicinal food
pub_type： 杂志文章,评审
doi：10.1089/jmf.2008.0115
更新日期：2010-04-01 00:00:00
abstract：:This study researched the effects of Lactobacillus plantarum PMO 08 alone and combined with chia seeds on metabolic syndrome and parameters related to microbiota modulation and intestinal barrier integrity in obese mice fed high-fat diets (HFDs; 45% kcal fat). Male C57BL/6J mice were acclimated for a period of 2 weeks...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2018.4349
更新日期：2019-12-01 00:00:00
abstract：:This study evaluates the effects of green tea polyphenols (GTPs) on bone microarchitecture in high-fat-diet (HFD)-induced obese female rats. Thirty-six 3-month-old female rats were fed either a control diet or a HFD for 4 months. Animals in the control group continued on the control diet for another 4 months. Animals ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.0199
更新日期：2013-05-01 00:00:00
abstract：:Candidiasis is the most frequent infection by opportunistic fungi, frequently caused by Candida albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata, and Candida krusei. Mentha arvensis L. is a herbaceous plant that occurs throughout South America and is used as a tea and in the folk medicine. Turnera ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2011.0128
更新日期：2012-03-01 00:00:00
abstract：:The ethyl acetate, methanol, and water extracts of 16 Ballota species (Family Lamiaceae)-Ballota acetabulosa, Ballota antalyanse, Ballota cristata, Ballota glandulosissima, Ballota inaequidens, Ballota larendana, Ballota latibracteolata, Ballota macrodonta, Ballota nigra ssp. anatolica, B. nigra ssp. foetida, B. nigra...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.0237
更新日期：2010-12-01 00:00:00
abstract：:This study investigated the effects and possible mechanism of ferulic acid, a naturally occurring phenolic compound, on endogenous glutamate release in the nerve terminals of the cerebral cortex in rats. Results show that ferulic acid inhibited the release of glutamate evoked by the K⁺ channel blocker 4-aminopyridine ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.2387
更新日期：2013-02-01 00:00:00
abstract：:Antioxidant capacity and polyphenolic content of leaf infusions prepared from six highbush blueberry cultivars (Vaccinium corymbosum L.), one wild lowbush blueberry cultivar (Vaccinium myrtillus L.), and one commercially available mix of genotypes were determined. In order to simulate household tea preparation conditi...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2008.0081
更新日期：2009-06-01 00:00:00
abstract：:Abnormal expression of pro-inflammatory mediators such as cell adhesion molecules and cytokines has been implicated in various inflammatory skin diseases, including atopic dermatitis. In this study, we investigated the anti-inflammatory activity of Aronia melanocarpa concentrate (AC) and its action mechanisms using in...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2015.3624
更新日期：2016-07-01 00:00:00
abstract：:High glucose levels can change podocyte gene expression and subsequently induce podocyte damage through altered glucose metabolism. l-Carnitine is known to play a beneficial role in diabetes; however, there are no studies on the effects of l-carnitine on podocyte alteration under high glucose conditions. This study in...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2010.1079
更新日期：2010-12-01 00:00:00
abstract：:The extract enriched in total oligomer flavonoids (TOF), and the aqueous, methanol, and ethyl acetate extracts of Acacia salicina were investigated for their polyphenolic compound content, antioxidative activity in the nitro blue tetrazolium/riboflavin assay system, antibacterial activity against Gram-positive and Gra...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2008.0120
更新日期：2009-06-01 00:00:00
abstract：:Astaxanthine (ASTx) is a novel carotenoid nutraceutical occurring in many crustaceans and red yeasts. It has potent antioxidant, photoprotective, hepatodetoxicant, and anti-inflammatory activities. Documented effect of ASTx on treatment of neurodegenerative disease is still lacking. We used the beta-amyloid peptide (A...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.1291
更新日期：2010-06-01 00:00:00
abstract：:Traditional herbal remedies stimulate and modulate the immune system, and it is thought that their glycoproteins and polysaccharides are responsible for this activity. We prepared crude water, protein, and polysaccharide extracts from Atractylodes macrocephala Koidz, Helianthus annuus L., Scutellaria barbata D. Don, a...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2017.3943
更新日期：2017-10-01 00:00:00
abstract：:Panax ginseng (P. ginseng C.A. Meyer, Araliaceae) is used as a therapeutic agent for various diseases. P. ginseng saponins, known as ginsenosides, are the main bioactive compounds responsible for its pharmacological activities. In this work, we have developed a new method of P. ginseng root processing termed solid-sta...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2017.4035
更新日期：2018-04-01 00:00:00
abstract：:Species of Hoodia Sweet ex Decne., family Apocynaceae, a southern African succulent plant, have been recognized for their appetite suppressing properties. Products that support appetite and weight control have been developed in Israel from locally cultivated Hoodia spp. To study consumer acceptance, efficacy of, and t...
journal_title：Journal of medicinal food
pub_type： 杂志文章,随机对照试验
doi：10.1089/jmf.2013.0178
更新日期：2015-02-01 00:00:00
abstract：:Since ancient times, oak wood polyphenols are consumed concomitantly with beverages that are stored and aged in oak wood barrels. Among these polyphenols are roburins, which belong to the class of ellagitannins and only occur in oak. To date, water-extracted standardized French Quercus robur wood extract, commercially...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2020.0165
更新日期：2021-01-28 00:00:00
abstract：:The antimicrobial effect of mastic gum, an ancient remedy for oral malodor, against Porphyromonas gingivalis, a known odorogenic periopathogenic oral bacterium, was tested using the agar diffusion test. Paper discs impregnated with mastic gum methanolic extract (MME) [0.5-4% (wt/vol)] produced inhibition zones of 10.5...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2006.9.290
更新日期：2006-07-01 00:00:00
abstract：:Mercury is a well-known environmental pollutant that can cause nephropathic diseases, including acute kidney injury (AKI). Although quercetin (QC), a natural flavonoid, has been reported to have medicinal properties, its potential protective effects against mercury-induced AKI have not been evaluated. In this study, t...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2014.3242
更新日期：2015-05-01 00:00:00
abstract：:Insufficient sleep, insomnia, and sleep-related problems are important health issues, as their overall prevalence accounts for about 30% of the general population. The aim of this study was to systematically review previous studies investigating the effects of orally administered single plant-derived extracts on sleep...
journal_title：Journal of medicinal food
pub_type： 杂志文章,评审
doi：10.1089/jmf.2017.4064
更新日期：2018-05-01 00:00:00
abstract：:Worldwide prevalence of noncommunicable chronic degenerative diseases is among the main causes of death worldwide. The consumption of some foods such as nuts and seeds may be beneficial in preventing these diseases. Dipteryx alata Vogel (DA), known popularly as Baru, belongs to the family Fabaceae and is a native frui...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2017.0052
更新日期：2017-11-01 00:00:00
abstract：:The relative dialysability of magnesium in a number of different inorganic and organic magnesium-containing compounds from ten commercially available products was investigated using an in vitro method. Reference values were provided by tests carried out in parallel using comparable quantities of pure magnesium compoun...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.1999.2.65
更新日期：1999-01-01 00:00:00
