Chest radiography or chest CT plus head and neck CT versus 18F-FDG PET/CT for detection of distant metastasis and synchronous cancer in patients with head and neck cancer.

abstract：OBJECTIVES:Cancer-associated fibroblasts (CAFs) play an important role in tumor progression and are associated with a poor prognosis. Tumor necrosis factor α (TNFα) has been involved in growth and metastasis associated with epithelial-mesenchymal transition (EMT) in many types of cancers. However, the relationship amon...

journal_title：Oral oncology

authors： Zhou B,Zhuang XM,Wang YY,Lin ZY,Zhang DM,Fan S,Li JS,Chen WL

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:A standardized assay to determine the HPV status of head and neck squamous cell carcinoma (HNSCC) specimens has not yet been established, particularly for cytologic samples. The goal of this study was to determine whether the hybrid capture-2 (HC-2) assay, already widely used for the detection of high risk HP...

journal_title：Oral oncology

authors： Smith DF,Maleki Z,Coughlan D,Gooi Z,Akpeng B,Ogawa T,Bishop JA,Frick KD,Agrawal N,Gourin CG,Ha PK,Koch WM,Richmon JD,Westra WH,Pai SI

更新日期：2014-06-01 00:00:00

abstract：:Expression profile of 588 known genes relating to tumour biology, was examined between oral squamous cell carcinomas (OSCCs) and matching normal oral mucosal tissues (NOMTs) obtained from Sudanese (n=11) and Norwegian (n=11) patients. cDNA probes were synthesised from total RNA and hybridised with the Atlas human canc...

journal_title：Oral oncology

authors： Ibrahim SO,Aarsaether N,Holsve MK,Kross KW,Heimdal JH,Aarstad JH,Liavaag PG,Elgindi OA,Johannessen AC,Lillehaug JR,Vasstrand EN

更新日期：2003-01-01 00:00:00

abstract：:Controversy remains about which patients at intermediate risk of recurrence of oral squamous cell carcinoma would benefit from radiotherapy. A retrospective review of computerised database and medical records for 462 consecutive patients at the Regional Maxillofacial Unit in Liverpool who were treated with primary sur...

journal_title：Oral oncology

authors： Brown JS,Blackburn TK,Woolgar JA,Lowe D,Errington RD,Vaughan ED,Rogers SN

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:High risk human papillomavirus (HR-HPV) infection leads to a subgroup of oropharyngeal cancer (OPSCC) characterized by improved treatment response. However an universally accepted definition of an HR-HPV-attributable cancer is lacking. METHODS:Detailed, type-specific HPV antibody responses were analyzed by ...

journal_title：Oral oncology

authors： Broglie MA,Jochum W,Michel A,Waterboer T,Foerbs D,Schoenegg R,Stoeckli SJ,Pawlita M,Holzinger D

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Adenoid cystic carcinomas (ACC) are characterized by high rate of local recurrence and late distant metastasis. Chromosomal changes in the evolution from primary tumors to metastatic disease of ACC have not been appointed. Here we investigated the chromosomal alterations of 53 primary tumors from...

journal_title：Oral oncology

authors： Cordesmeyer R,Laskawi R,Schliephake H,Kauffmann P,Beck J,Bornemann-Kolatzki K,Schütz E,Ströbel P,Kueffer S,Fichtner A,Bremmer F

更新日期：2020-04-01 00:00:00

abstract：:We have investigated whether Ginkgo biloba extract (EGb 761) induces apoptosis of oral cavity cancer cells and attempted to characterize the apoptotic pathway activated by EGb 761. The inhibition of SCC 1483 oral cavity cancer cells proliferation was noted from 250 micro/ml of EGb 761. Apoptosis was observed after 24 ...

journal_title：Oral oncology

authors： Kim KS,Rhee KH,Yoon JH,Lee JG,Lee JH,Yoo JB

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The programmed death pathway plays a role in persistent human papillomavirus (HPV) infection as well as in resistance to immune elimination during malignant progression. In this study, we examined PD-L1 expression by immunohistochemistry and tumour infiltrating lymphocytes (TIL) in 214 patients with orophary...

journal_title：Oral oncology

authors： Hong AM,Ferguson P,Dodds T,Jones D,Li M,Yang J,Scolyer RA

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:Healthy life expectancy, an extension of the concept of life expectancy, is a summary measure of population health that takes into account the mortality and morbidity of a population. The aim of the present study was to retrospectively analyze the self-reliance survival times of oral squamous cell carcinoma ...

journal_title：Oral oncology

authors： Yamada SI,Kurita H,Tomioka T,Ohta R,Yoshimura N,Nishimaki F,Koyama Y,Kondo E,Kamata T

更新日期：2017-01-01 00:00:00

abstract：:In recent years, studies on the malignant potential of oral lichen planus (OLP) provided clinical evidence that patients affected by OLP have an increased risk to develop oral squamous cell carcinoma (OSCC); nevertheless, controversies still exist as to whether OLP has inherent predisposition to become malignant, or n...

journal_title：Oral oncology

authors： Mignogna MD,Lo Muzio L,Lo Russo L,Fedele S,Ruoppo E,Bucci E

更新日期：2001-04-01 00:00:00

abstract：:The hormonal regulation of Na+,K(+)-ATPase enzyme activities and induction of the alpha subunit protein of the enzyme in the human submandibular gland (HSG) were studied by use of cultured HSG cells. We treated HSG cells with thyroid hormone, androgen, mineralocorticoid, and glucocorticoid, singly or in combination. 3...

journal_title：Oral oncology

authors： Kurihara K,Tajima Y,Kawasaki M,Ueha T

更新日期：1999-07-01 00:00:00

abstract：:Indole-3-carbinol (I3C), a naturally occurring phytochemical found in cruciferous vegetables, has received much attention due to its translational potential in cancer prevention and therapy. In this study, we investigated the antitumor effects of OSU-A9, a structurally optimized I3C derivative, in a panel of oral squa...

journal_title：Oral oncology

authors： Weng JR,Bai LY,Omar HA,Sargeant AM,Yeh CT,Chen YY,Tsai MH,Chiu CF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:A multi-disciplinary team (MDT) is essential in the management of cancer. Head and neck cancer (HNC) is a rare, complex and heterogeneous group of malignancies for which different treatment options are available. However, the potential impact of MDT on the management of HNC has been only poorly evaluated to ...

journal_title：Oral oncology

authors： Bergamini C,Locati L,Bossi P,Granata R,Alfieri S,Resteghini C,Imbimbo M,Fallai C,Orlandi E,Tana S,Iacovelli NA,Guzzo M,Ibba T,Colombo S,Bianchi R,Pizzi N,Fontanella W,Licitra L

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Excision repair crosscomplementing-1 (ERCC1) has been reported to play a prognostic role and may indicate the treatment response in patients with head and neck squamous carcinoma (HNSCC). Nevertheless, the strength of evidence of ERCC1 predicting these two clinical outcomes are still controversial. METHODS:...

journal_title：Oral oncology

authors： Xuelei M,Jingwen H,Wei D,Hongyu Z,Jing Z,Changle S,Lei L

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Genetic polymorphisms of genes in cell cycle, apoptosis, and inflammation/immune response pathways may control the mechanisms of HPV clearance and HPV escape of immune surveillance and thus may affect both tumor HPV16 status and possibly related outcomes of squamous cell carcinoma of the oropharynx (SCCOP) p...

journal_title：Oral oncology

authors： Feng Y,Li Y,Zhang Y,Zheng H,Li G

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:We investigated the effect of prophylactic oral nutrition supplements (ONS) in locally advanced nasopharyngeal carcinoma patients receiving neoadjuvant chemotherapy and concurrent chemoradiotherapy (CCRT). METHODS:Eligible patients were randomly assigned to an intervention or control group. Patients in the ...

journal_title：Oral oncology

authors： Huang S,Piao Y,Cao C,Chen J,Sheng W,Shu Z,Hua Y,Jiang F,Hu Q,Chen X,Chen Y

更新日期：2020-12-01 00:00:00

abstract：:Salivary duct carcinoma (SDC) is a rare, aggressive salivary malignancy that is often diagnosed at an advanced stage. Previously, little was known about outcomes of this disease due to its rarity. In the past several years, much has been learned about salivary duct carcinoma after publication of outcomes from several ...

journal_title：Oral oncology

authors： Schmitt NC,Kang H,Sharma A

更新日期：2017-11-01 00:00:00

abstract：:Adenocarcinoma of the minor salivary gland (MSG) is a rare neoplasm. It represents about 2% of all MSG malignant tumours. It is more common in the palate and in females. This tumour occurs in a mean age of sixty and its mean size at presentation is 1.5cm. Microscopically, the neoplasms classified as adenocarcinoma not...

journal_title：Oral oncology

authors： Moreno M,Moreno A,Tomé C

更新日期：2008-03-01 00:00:00

abstract：:Previous work from our laboratory has demonstrated overexpression of chemokines in head and neck cancer and the utility of targeting these proteins for tumor therapy in a preclinical model. However, the mechanisms involved are unexplored. Through gene expression analysis, we found that expression of vascular endotheli...

journal_title：Oral oncology

authors： Benke EM,Ji Y,Patel V,Wang H,Miyazaki H,Yeudall WA

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:Disruption of E-cadherin function and increased expression of vimentin and the transcriptional oncogene, SOX2, are thought to characterize epithelial to mesenchymal transition (EMT) in HNSCC that contributes to invasive and metastatic behavior. To determine if such changes relate to prognosis or host immun...

journal_title：Oral oncology

authors： Wolf GT,Winter W,Bellile E,Nguyen A,Donnelly CR,McHugh JB,Thomas D,Amlani L,Rozek L,Lei YL,Head and Neck SPORE Program.

更新日期：2018-12-01 00:00:00

abstract：:In loco-regionally advanced head and neck squamous cell cancer (HNSCC), concurrent 3-weekly cisplatin improves overall survival (OS) compared to radiotherapy alone, but is often associated with renal toxicity. The use of radiotherapy with accelerated fractionation schedules has been reported to improve survival but it...

journal_title：Oral oncology

authors： Espeli V,Zucca E,Ghielmini M,Giannini O,Salatino A,Martucci F,Richetti A

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Esophageal second primary tumors (SPTs) in head and neck cancer (HNC) patients is not uncommon. The impact of image-enhanced endoscopy (IEE) screening for esophageal SPT on the outcome of HNC patients has not been well clarified. METHODS AND METHODS:Patients with malignancies of the head and neck region and...

journal_title：Oral oncology

authors： Chung CS,Lo WC,Chen KC,Lin CL,Wen MH,Hsieh CH,Lin SC,Liao LJ

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:A systematic review to establish what evidence is available for swallowing outcomes following IMRT for head and neck cancer. METHODS:Online electronic databases were searched to identify papers published in English from January 1998 to December 2009. Papers were independently appraised by two reviewers for met...

journal_title：Oral oncology

authors： Roe JW,Carding PN,Dwivedi RC,Kazi RA,Rhys-Evans PH,Harrington KJ,Nutting CM

更新日期：2010-10-01 00:00:00

abstract：:Our previous study demonstrated that overexpression of Id-1 (inhibitor of differentiation/DNA binding) was associated with lymphatic metastasis in human oral squamous cell carcinoma (OSCC). In this study, we further unveiled the association of Id-1 with vascular endothelial growth factor-C (VEGF-C) and peritumoral lym...

journal_title：Oral oncology

authors： Dong Z,Wei F,Zhou C,Sumida T,Hamakawa H,Hu Y,Liu S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Oral leukoplakia is a precancerous disorder that is common among residents in Linxian. However, the associations between oral leukoplakia and upper gastrointestinal cancers have not been reported. We investigated the relationships between oral leukoplakia and upper gastrointestinal cancers in the Linxian Gen...

journal_title：Oral oncology

authors： Fan JH,Wang JB,Qu CX,Zhang YQ,Taylor PR,Abnet CC,Dawsey SM,Qiao YL

更新日期：2014-10-01 00:00:00

abstract：:Emerging evidence suggests the existence of a tumorigenic population of cancer cells that demonstrate stem cell-like properties such as self-renewal and multipotency. These cells, termed cancer stem cells (CSC), are able to both initiate and maintain tumor formation and progression. Studies have shown that CSC are res...

journal_title：Oral oncology

authors： Adams A,Warner K,Nör JE

更新日期：2013-09-01 00:00:00

abstract：:The purpose of this systematic review and meta-analysis was to evaluate the diagnostic value of salivary biological markers in the diagnosis of head and neck carcinoma. Studies were gathered by searching Cochrane, EMBASE, LILACS, MEDLINE, and PubMed. The references were also crosschecked and a partial grey literature ...

journal_title：Oral oncology

authors： Guerra EN,Acevedo AC,Leite AF,Gozal D,Chardin H,De Luca Canto G

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:To assess the effect of the histological margins (HM) upon locoregional failure (LRF) and overall survival (OS) for oral tongue squamous cell carcinoma (OTSCC). MATERIALS AND METHODS:We undertook a retrospective review of 258 patients, across two institutions, treated for OTSCC between 2007 and 2016. A Cox-...

journal_title：Oral oncology

authors： Daniell J,Udovicich C,Rowe D,McDowell L,Vital D,Bressel M,Magarey MJR,Iseli TA,Wong T,Lekgabe E,Cavanagh K,Fua T,Rischin D,Wiesenfeld D

更新日期：2020-12-01 00:00:00

abstract：:Primary oral melanoma (POM) is a rare form of melanoma, generally diagnosed at a late stage and has poor prognosis. Epidemiological information has scarcely been reported in the literature over the past 40 years. Analyzing the Cancer Incidence in Five Continents volume IX (CI5-IX) database we found a total of 124,436 ...

journal_title：Oral oncology

authors： Sortino-Rachou AM,Cancela Mde C,Voti L,Curado MP

更新日期：2009-03-01 00:00:00

abstract：:The presence of distant metastasis after the initial treatment of head and neck squamous cell carcinoma is not considered a common event and is associated with a poor outcome. The objective of this study was to investigate the prevalence and risk factors associated with the diagnosis of distant metastasis in oral and ...

journal_title：Oral oncology

authors： Kowalski LP,Carvalho AL,Martins Priante AV,Magrin J

更新日期：2005-05-01 00:00:00