Enhancing performance in numerical magnitude processing and mental arithmetic using transcranial Direct Current Stimulation (tDCS).

Abstract:

:The ability to accurately process numerical magnitudes and solve mental arithmetic is of highest importance for schooling and professional career. Although impairments in these domains in disorders such as developmental dyscalculia (DD) are highly detrimental, remediation is still sparse. In recent years, transcranial brain stimulation methods such as transcranial Direct Current Stimulation (tDCS) have been suggested as a treatment for various neurologic and neuropsychiatric disorders. The posterior parietal cortex (PPC) is known to be crucially involved in numerical magnitude processing and mental arithmetic. In this study, we evaluated whether tDCS has a beneficial effect on numerical magnitude processing and mental arithmetic. Due to the unclear lateralization, we stimulated the left, right as well as both hemispheres simultaneously in two experiments. We found that left anodal tDCS significantly enhanced performance in a number comparison and a subtraction task, while bilateral and right anodal tDCS did not induce any improvements compared to sham. Our findings demonstrate that the left PPC is causally involved in numerical magnitude processing and mental arithmetic. Furthermore, we show that these cognitive functions can be enhanced by means of tDCS. These findings encourage to further investigate the beneficial effect of tDCS in the domain of mathematics in healthy and impaired humans.

journal_name

Front Hum Neurosci

authors

Hauser TU,Rotzer S,Grabner RH,Mérillat S,Jäncke L

doi

10.3389/fnhum.2013.00244

subject

Has Abstract

pub_date

2013-06-06 00:00:00

pages

244

issn

1662-5161

journal_volume

7

pub_type

杂志文章
  • A predictive nature for tactile awareness? Insights from damaged and intact central-nervous-system functioning.

    abstract::In the present paper, we will attempt to gain hints regarding the nature of tactile awareness in humans. At first, we will review some recent literature showing that an actual tactile experience can emerge in absence of any tactile stimulus (e.g., tactile hallucinations, tactile illusions). According to the current mo...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00287

    authors: Pia L,Garbarini F,Burin D,Fossataro C,Berti A

    更新日期:2015-05-19 00:00:00

  • Slow Is Also Fast: Feedback Delay Affects Anxiety and Outcome Evaluation.

    abstract::Performance-related feedback plays an important role in improving human being's adaptive behavior. Using event-related potentials (ERPs), previous studies have associated a particular component, i.e., reward positivity (RewP), with outcome evaluation processing and found that this component was affected by waiting tim...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00020

    authors: Zhang X,Lei Y,Yin H,Li P,Li H

    更新日期:2018-01-25 00:00:00

  • More Than Words: Extra-Sylvian Neuroanatomic Networks Support Indirect Speech Act Comprehension and Discourse in Behavioral Variant Frontotemporal Dementia.

    abstract::Indirect speech acts-responding "I forgot to wear my watch today" to someone who asked for the time-are ubiquitous in daily conversation, but are understudied in current neurobiological models of language. To comprehend an indirect speech act like this one, listeners must not only decode the lexical-semantic content o...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.598131

    authors: Healey M,Howard E,Ungrady M,Olm CA,Nevler N,Irwin DJ,Grossman M

    更新日期:2021-01-14 00:00:00

  • Are treatment effects of neurofeedback training in children with ADHD related to the successful regulation of brain activity? A review on the learning of regulation of brain activity and a contribution to the discussion on specificity.

    abstract::While issues of efficacy and specificity are crucial for the future of neurofeedback training, there may be alternative designs and control analyses to circumvent the methodological and ethical problems associated with double-blind placebo studies. Surprisingly, most NF studies do not report the most immediate result ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2015.00135

    authors: Zuberer A,Brandeis D,Drechsler R

    更新日期:2015-03-27 00:00:00

  • Investigating developmental changes in sensory processing: visual mismatch response in healthy children.

    abstract::The ability to detect small changes in one's visual environment is important for effective adaptation to and interaction with a wide variety of external stimuli. Much research has studied the auditory mismatch negativity (MMN), or the brain's automatic response to rare changes in a series of repetitive auditory stimul...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00922

    authors: Cleary KM,Donkers FC,Evans AM,Belger A

    更新日期:2013-12-30 00:00:00

  • Voluntary Out-of-Body Experience: An fMRI Study.

    abstract::The present single-case study examined functional brain imaging patterns in a participant that reported being able, at will, to produce somatosensory sensations that are experienced as her body moving outside the boundaries of her physical body all the while remaining aware of her unmoving physical body. We found that...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00070

    authors: Smith AM,Messier C

    更新日期:2014-02-10 00:00:00

  • The other side of the coin: oxytocin decreases the adherence to fairness norms.

    abstract::Oxytocin (OXT) has been implicated in prosocial behaviors such as trust and generosity. Yet, these effects appear to strongly depend on characteristics of the situation and the people with whom we interact or make decisions. Norms and rules can facilitate and guide our actions, with fairness being a particularly salie...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00193

    authors: Radke S,de Bruijn ER

    更新日期:2012-06-28 00:00:00

  • Extrastriate visual cortex reorganizes despite sequential bilateral occipital stroke: implications for vision recovery.

    abstract::The extent of visual cortex reorganization following injury remains controversial. We report serial functional magnetic resonance imaging (fMRI) data from a patient with sequential posterior circulation strokes occurring 3 weeks apart, compared with data from an age-matched healthy control subject. At 8 days following...

    journal_title:Frontiers in human neuroscience

    pub_type:

    doi:10.3389/fnhum.2015.00224

    authors: Brodtmann A,Puce A,Darby D,Donnan G

    更新日期:2015-04-28 00:00:00

  • Luminance gradient configuration determines perceived lightness in a simple geometric illusion.

    abstract::Accurate perception of surface reflectance poses a significant computational problem for the visual system. The amount of light reflected by a surface is affected by a combination of factors including the surface's reflectance properties and illumination conditions. The latter are not limited by the strength of the il...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00977

    authors: Pereverzeva M,Murray SO

    更新日期:2014-12-05 00:00:00

  • Evaluating the relationship between change in performance on training tasks and on untrained outcomes.

    abstract::Training interventions for older adults are designed to remediate performance on trained tasks and to generalize, or transfer, to untrained tasks. Evidence for transfer is typically based on the trained group showing greater improvement than controls on untrained tasks, or on a correlation between gains in training an...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00617

    authors: Zelinski EM,Peters KD,Hindin S,Petway KT 2nd,Kennison RF

    更新日期:2014-08-13 00:00:00

  • Functional Preservation and Reorganization of Brain during Motor Imagery in Patients with Incomplete Spinal Cord Injury: A Pilot fMRI Study.

    abstract::Motor imagery (MI) is a cognitive process involved in mentally rehearsing movement representations, and it has great potential for the rehabilitation of motor function in patients with spinal cord injuries. The aim of this study was to explore changes in the brain activation patterns in incomplete spinal cord injury (...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00046

    authors: Chen X,Wan L,Qin W,Zheng W,Qi Z,Chen N,Li K

    更新日期:2016-02-15 00:00:00

  • Spontaneous Fluctuations in Sensory Processing Predict Within-Subject Reaction Time Variability.

    abstract::When engaged in a repetitive task our performance fluctuates from trial-to-trial. In particular, inter-trial reaction time variability has been the subject of considerable research. It has been claimed to be a strong biomarker of attention deficits, increases with frontal dysfunction, and predicts age-related cognitiv...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00200

    authors: Ribeiro MJ,Paiva JS,Castelo-Branco M

    更新日期:2016-05-09 00:00:00

  • Comparing the neural distance effect derived from the non-symbolic comparison and the same-different task.

    abstract::As a result of the representation of numerosities, more accurate and faster discrimination between two numerosities is observed when the distance between them increases. In previous studies, the comparison and same-different task were most frequently used to investigate this distance effect. Recently, it was questione...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00028

    authors: Smets K,Gebuis T,Reynvoet B

    更新日期:2013-02-14 00:00:00

  • Dissociation of category-learning systems via brain potentials.

    abstract::Behavioral, neuropsychological, and neuroimaging evidence has suggested that categories can often be learned via either an explicit rule-based (RB) mechanism critically dependent on medial temporal and prefrontal brain regions, or via an implicit information-integration (II) mechanism relying on the basal ganglia. In ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00389

    authors: Morrison RG,Reber PJ,Bharani KL,Paller KA

    更新日期:2015-07-07 00:00:00

  • The Effect of Healthy Diet on Cognitive Performance Among Healthy Seniors - A Mini Review.

    abstract::At present, a healthy diet appears to be one of the suitable strategies in slowing down cognitive decline in the process of aging. A number of evidence-based studies confirm its efficacy, safety, and cost-effectiveness. The aim of this mini review is to evaluate and describe recent randomized clinical and cohort studi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2020.00325

    authors: Klimova B,Dziuba S,Cierniak-Emerych A

    更新日期:2020-08-11 00:00:00

  • Transcranial Direct Current Stimulation Modulates the Effect of Unreasonable Request in the Context of Peer Punishment.

    abstract::Making a request is a common occurrence during social interactions. In most social contexts, requesters may impose punishments and many behavioral studies have focused on the differential effects of reasonable and unreasonable requests during such interactions. However, few studies have explored whether reasonable or ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00255

    authors: Pan J,Zhu C,Liu X,Wang Y,Li J

    更新日期:2019-07-30 00:00:00

  • Altered Structural Correlates of Impulsivity in Adolescents with Internet Gaming Disorder.

    abstract::Recent studies suggested that internet gaming disorder (IGD) was associated with impulsivity and structural abnormalities in brain gray matter (GM). However, no morphometric study has examined the association between GM and impulsivity in IGD individuals. In this study, 25 adolescents with IGD and 27 healthy controls ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00004

    authors: Du X,Qi X,Yang Y,Du G,Gao P,Zhang Y,Qin W,Li X,Zhang Q

    更新日期:2016-01-28 00:00:00

  • Corrigendum: GRETNA: a graph theoretical network analysis toolbox for imaging connectomics.

    abstract::[This corrects the article on p. 386 in vol. 9, PMID: 26175682.]. ...

    journal_title:Frontiers in human neuroscience

    pub_type: 已发布勘误

    doi:10.3389/fnhum.2015.00458

    authors: Wang J,Wang X,Xia M,Liao X,Evans A,He Y

    更新日期:2015-08-19 00:00:00

  • Low or High-Level Motor Coding? The Role of Stimulus Complexity.

    abstract::Transcranial magnetic stimulation (TMS) studies have shown that observing an action induces activity in the onlooker's motor system. In light of the muscle specificity and time-locked mirroring nature of the effect, this motor resonance has been traditionally viewed as an inner automatic replica of the observed moveme...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2019.00332

    authors: Amoruso L,Finisguerra A

    更新日期:2019-10-11 00:00:00

  • Variation in Event-Related Potentials by State Transitions.

    abstract::The probability of an event's occurrence affects event-related potentials (ERPs) on electroencephalograms. The relation between probability and potentials has been discussed by using a quantity called surprise that represents the self-information that humans receive from the event. Previous studies have estimated surp...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00075

    authors: Higashi H,Minami T,Nakauchi S

    更新日期:2017-02-27 00:00:00

  • Cognitive control signals in posterior cingulate cortex.

    abstract::Efficiently shifting between tasks is a central function of cognitive control. The role of the default network - a constellation of areas with high baseline activity that declines during task performance - in cognitive control remains poorly understood. We hypothesized that task switching demands cognitive control to ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00223

    authors: Hayden BY,Smith DV,Platt ML

    更新日期:2010-12-06 00:00:00

  • Transcranial Magnetic Stimulation Reveals Executive Control Dissociation in the Rostral Prefrontal Cortex.

    abstract::Although previous studies have shown that the rostral prefrontal cortex (rPFC) plays a crucial role in executive tasks, the various functions of the rPFC in the humans are still understudied. Here we used transcranial magnetic stimulation (TMS) with continuous theta burst stimulation (cTBS) to interfere with the execu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00464

    authors: He W,Fan C,Li L

    更新日期:2017-09-22 00:00:00

  • The Monetary Incentive Delay (MID) Task Induces Changes in Sensory Processing: ERP Evidence.

    abstract::Numerous cognitive studies have demonstrated experience-induced plasticity in the primary sensory cortex, indicating that repeated decisions could modulate sensory processing. In this context, we investigated whether an auditory version of the monetary incentive delay (MID) task could change the neural processing of t...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00382

    authors: Krugliakova E,Gorin A,Fedele T,Shtyrov Y,Moiseeva V,Klucharev V,Shestakova A

    更新日期:2019-11-01 00:00:00

  • Brain Activity During Unilateral Physical and Imagined Isometric Contractions.

    abstract::By convention, it is believed that the ipsilateral side of the body is controlled by the contralateral side of the brain. Past studies measuring brain activity primarily recorded changes before and after an intervention is performed on one side of the body within one hemisphere (usually the contralateral) of the brain...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00413

    authors: Martinez JA,Wittstein MW,Folger SF,Bailey SP

    更新日期:2019-11-26 00:00:00

  • STN Versus GPi Deep Brain Stimulation for Action and Rest Tremor in Parkinson's Disease.

    abstract:Objective:To investigate the effects of subthalamic nucleus (STN) and globus pallidus internus (GPi), deep brain stimulation (DBS) on individual action tremor/postural tremor (AT) and rest tremor (RT) in Parkinson's disease (PD). Randomized DBS studies have reported marked benefit in tremor with both GPi and STN and DB...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.578615

    authors: Wong JK,Viswanathan VT,Nozile-Firth KS,Eisinger RS,Leone EL,Desai AM,Foote KD,Ramirez-Zamora A,Okun MS,Wagle Shukla A

    更新日期:2020-10-23 00:00:00

  • Proactive Information Sampling in Value-Based Decision-Making: Deciding When and Where to Saccade.

    abstract::Evidence accumulation has been the core component in recent development of perceptual and value-based decision-making theories. Most studies have focused on the evaluation of evidence between alternative options. What remains largely unknown is the process that prepares evidence: how may the decision-maker sample diff...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00035

    authors: Song M,Wang X,Zhang H,Li J

    更新日期:2019-02-11 00:00:00

  • Differential influence of levodopa on reward-based learning in Parkinson's disease.

    abstract::The mesocorticolimbic dopamine (DA) system linking the dopaminergic midbrain to the prefrontal cortex and subcortical striatum has been shown to be sensitive to reinforcement in animals and humans. Within this system, coexistent segregated striato-frontal circuits have been linked to different functions. In the presen...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00169

    authors: Graef S,Biele G,Krugel LK,Marzinzik F,Wahl M,Wotka J,Klostermann F,Heekeren HR

    更新日期:2010-10-14 00:00:00

  • Recovery of resting brain connectivity ensuing mild traumatic brain injury.

    abstract::Brains reveal amplified plasticity as they recover from an injury. We aimed to define time dependent plasticity changes in patients recovering from mild traumatic brain injury (mTBI). Twenty-five subjects with mild head injury were longitudinally evaluated within 36 h, 3 and 6 months using resting state functional con...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2015.00513

    authors: Bharath RD,Munivenkatappa A,Gohel S,Panda R,Saini J,Rajeswaran J,Shukla D,Bhagavatula ID,Biswal BB

    更新日期:2015-09-22 00:00:00

  • Exploring Training Effect in 42 Human Subjects Using a Non-invasive Sensorimotor Rhythm Based Online BCI.

    abstract::Electroencephalography based brain-computer interfaces (BCIs) show promise of providing an alternative communication channel between the brain and an external device. It is well acknowledged that BCI control is a skill and could be improved through practice and training. In this study, we explore the change of BCI beh...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00128

    authors: Meng J,He B

    更新日期:2019-04-17 00:00:00

  • Children with Spastic Cerebral Palsy Experience Difficulties Adjusting Their Gait Pattern to Weight Added to the Waist, While Typically Developing Children Do Not.

    abstract::The prevalence of childhood overweight and obesity is increasing in the last decades, also in children with Cerebral Palsy (CP). Even though it has been established that an increase in weight can have important negative effects on gait in healthy adults and children, it has not been investigated what the effect is of ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00657

    authors: Meyns P,Van Gestel L,Bar-On L,Goudriaan M,Wambacq H,Aertbeliën E,Bruyninckx H,Molenaers G,De Cock P,Ortibus E,Desloovere K

    更新日期:2016-12-23 00:00:00