Abstract：
BACKGROUND:Is it healthy to be chaotic? Recent studies have argued that mental disorders are associated with more orderly neural activities, corresponding to a less flexible functional system. These conclusions were derived from altered temporal complexity. However, the relationship between spatial complexity and health is unknown, although spatial configuration is of importance for normal brain function. METHODS:Based on resting-state functional magnetic resonance imaging data, we used Sample entropy (SampEn) to evaluate the altered spatial complexity in patients with generalized anxiety disorder (GAD; n = 47) compared to healthy controls (HCs; n = 38) and the relationship between spatial complexity and anxiety level. RESULTS:Converging results showed increased spatial complexity in patients with GAD, indicating more chaotic spatial configuration. Interestingly, inverted-U relationship was revealed between spatial complexity and anxiety level, suggesting complex relationship between health and the chaos of human brain. LIMITATIONS:Anxiety-related alteration of spatial complexity should be verified at voxel level in a larger sample and compared with results of other indices to clarify the mechanism of spatial chaotic of anxiety. CONCLUSIONS:Altered spatial complexity in the brain of GAD patients mirrors inverted-U relationship between anxiety and behavioral performance, which may reflect an important characteristic of anxiety. These results indicate that SampEn is a good reflection of human health or trait mental characteristic.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Wang Y,Wang X,Ye L,Yang Q,Cui Q,He Z,Li L,Yang X,Zou Q,Yang P,Liu D,Chen Hdoi
10.1016/j.jad.2018.12.107subject
Has Abstractpub_date
2019-03-01 00:00:00pages
387-393eissn
0165-0327issn
1573-2517pii
S0165-0327(18)31853-6journal_volume
246pub_type
杂志文章abstract：BACKGROUND:Recent trials have demonstrated clinically meaningful efficacy and minimal cognitive side effects with ultrabrief pulsewidth right unilateral (RUL) ECT. In many countries it is gradually being adopted into clinical practice and further information on predictors of response is needed. METHODS:Data collected ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.09.016
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Little evidence exists regarding the costs of telemedicine, especially considering changes over time. This analysis aimed to analyze trajectory of healthcare cost before, during, and after a behavioral activation intervention delivered via telepsychology and same-room delivery to elderly Veterans with depres...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2016.09.044
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Cognitive reserve (CR) reflects the resilience of the brain to cope with neuropathological changes and minimize clinical manifestations. In the present study, we explore the association between CR and cognitive and psychosocial functioning, and examined the potential moderating role of CR in patients with bi...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.09.019
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Migraine is a common comorbidity among individuals with bipolar disorder, but the underlying mechanisms for this co-occurrence are poorly understood. The aim of this study was to investigate the genetic background of bipolar patients with and without migraine. METHODS:We performed a genome-wide association ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2014.10.004
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:The daily pattern of motor activity and the autonomic cardiovascular regulation were studied in major depression to quantify changes in psychomotor function and autonomic cardiac functioning. Additionally, relationships between motor activity parameters, cardiovascular measures and specific clinical features...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(02)00066-6
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Depression is a prevalent disorder with a peak rate of onset in young adulthood from 18 to 25 years. To date, no review has systematically assessed the effectiveness of programs that aim to reduce depressive symptoms or diagnosis of depression in young adults. METHOD:A systematic search was performed in Coc...
journal_title：Journal of affective disorders
pub_type： 杂志文章,meta分析
doi：10.1016/j.jad.2018.05.010
更新日期：2018-10-15 00:00:00
abstract：BACKGROUND:Psychotic major depression (PMD) and delusional misidentification syndromes (DMS) exhibit cognitive deficits. Since the P300 component of event-related potentials (ERPs) provides valuable information concerning cognition, we studied this component of ERPs in DMS and PMD patients. METHODS:Nine patients with ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/S0165-0327(03)00136-8
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to compare a newly developed screening measure of disability, the WHODAS II, to three established generic effectiveness measures in terms of its sensitivity to symptom change in people with anxiety disorders. METHOD:Patients who had undergone treatment for social phobia or panic...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2005.10.011
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:There remains considerable disagreement regarding the relative efficacy of psychotherapy and medication across types of depression. METHOD:We used random effects meta-analysis to examine the relative efficacy of psychotherapy vis-à-vis medication at post-treatment and follow-up. We also estimated the relati...
journal_title：Journal of affective disorders
pub_type： 杂志文章,meta分析
doi：10.1016/j.jad.2008.03.018
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, empl...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.10.039
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Depression is associated with a negative prognosis in coronary heart disease and heart failure patients. Type D personality has been shown to predict the persistence of depressive symptoms over 12 months. Data on longer follow-up periods and on the effectiveness of Type D as a screening tool compared to esta...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2011.11.044
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Depression in older adults is associated with neuropsychological dysfunction, fronto-subcortical brain changes and sleep disturbance. Research suggests that adequate sleep is critical for many aspects of cognition including processing speed, verbal skills and memory. However, the association between sleep di...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2008.11.017
更新日期：2009-07-01 00:00:00
abstract：:The authors made a follow-up study among 118 depressive patients. The follow-up period was 11 years (mean 7.8 years). They have used the operational criteria elaborated by Lee and Murray. The suicide rate was 2.54%, calculated for annual average per 100000 inhabitants is 231.5. This figure is close to ten times higher...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(99)00168-8
更新日期：2000-11-01 00:00:00
abstract：:Predicting response to antidepressant medication has been a challenge to clinicians and researchers for decades. Attention has been paid to the role of motor retardation as a putative indicator of treatment response, yet previous findings have been mixed. One reason for this inconsistency may be related to the subject...
journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0165-0327(02)00107-6
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:There is a well-known association between artistic creativity and cyclothymic temperament but the neural correlates of cyclothymic temperament have not yet been fully identified. Recently, we showed that the left lingual gyrus and bilateral cuneus may be associated with esthetic judgment of representational ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2014.07.037
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Patients with major depressive disorder (MDD) show neuropsychological impairments, including deficient executive functions and altered sensitivity to reward and punishment. METHODS:Executive functions (Wisconsin Card Sorting Test, WCST) and contingency learning based on the cumulative effect of reward and p...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2005.12.005
更新日期：2006-02-01 00:00:00
abstract：:Research on adolescent and adult populations has linked depression to variation in several monoaminergic genes, but genetic association studies on depression in children are limited. Additionally, few studies have investigated whether stressors occurring very early in development moderate the influence of certain gene...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.03.023
更新日期：2016-06-01 00:00:00
abstract：:Current formal psychiatric approaches to nosology are plagued by an unwieldy degree of heterogeneity with insufficient appreciation of the commonalities of emotional, personality, behavioral, and addictive disorders. We address this challenge by building a spectrum model that integrates the advantages of Cloninger's a...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2006.02.025
更新日期：2006-08-01 00:00:00
abstract：BACKGROUND:Axis I comorbidity in mood disorders was common in epidemiological studies. This study was designed to investigate the prevalence, pattern, and number of Axis I comorbidities and the role of the Quick Inventory of Depression Symptomatology - 16 items-Self-Report (QIDS-16-SR) in predicting the number of comor...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.12.004
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:This study sought to determine from a recent meta-analysis of pediatric antidepressant trials if a general property of antidepressant medications--the multiple-dosing medication half-life--is associated with risks for suicidal ideation or behavior. METHODS:Relative risks for suicidal behavior (ideation, att...
journal_title：Journal of affective disorders
pub_type： 杂志文章,meta分析
doi：10.1016/j.jad.2008.06.018
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:No research has yet focused on hypomanic states in non-clinical early adult populations. The aim of the present study was therefore to assess hypomania in a large non-clinical sample of young adults. METHODS:A total of 862 participants (639 females and 223 males; mean age: M=24.67; SD=5.91) took part in the...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.12.007
更新日期：2011-06-01 00:00:00
abstract：:The plasma prolactin response to thyrotropin-releasing hormone, which is thought to be mediated by central 5-HT mechanisms, has been studied in patients with affective disorders. There was no difference between depressive patients (taken as a whole), bipolar patients undergoing a manic phase and controls in the prolac...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(80)90032-4
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:Although the application of repetitive transcranial magnetic stimulation (rTMS) for treatment of depression has been well investigated, there are few biological predictors of clinical outcomes to rTMS treatment. Previous studies have suggested that the loudness dependence of auditory evoked potentials (LDAEP...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2018.05.023
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Tobacco use has been associated with externalized personality traits. Our aim was to evaluate the association of smoking with emotional and affective temperaments in a large sample. METHODS:In this cross-sectional web-based survey, volunteers completed the Combined Emotional and Affective Temperament Scale ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.04.016
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Our previous studies have proved that zinc supplement effectively alleviate depression symptoms in mice, but the mechanisms are still uncertain. Neuroinflammation is considered as an important aspect in pathogenesis of depression. To elucidate the role of zinc on neuroinflammation, in this study, we investig...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.02.041
更新日期：2019-04-15 00:00:00
abstract：BACKGROUND:Bipolar disorder (BD) is associated with later sleep and daily activity (evening rather than morning chronotype). Objective chronotype identification (e.g., based on actigraphs/smartphones) has potential utility, but to date, chronotype has mostly been assessed by questionnaires. Given the ubiquity of accele...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.08.032
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Clinicians view "recovery" as the reduction in severity of symptoms over time, whereas patients view it as the restoration of premorbid functioning level and quality of life (QOL). The main purpose of this study is to incorporate patient-reported measures of functioning and QOL into the assessment of patient...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.08.081
更新日期：2017-01-15 00:00:00
abstract：BACKGROUND:Abnormal social behaviour, which is a common feature of psychiatric disorders, is associated with rejection. A passive lack of participation or involvement has been studied as characteristic of depression but active forms of nonparticipation have received little experimental attention. This study examined th...
journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0165-0327(02)00036-8
更新日期：2003-06-01 00:00:00
abstract：:The relationship between ventricular brain ratio (VBR) and clinical variables was investigated in 21 DSM-III depressed patients. None of the following dichotomies--major depression vs. dysthymic disorder, suicidal vs. non-suicidal patients, male vs. female patients--showed any statistically significant differences. An...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(87)90035-8
更新日期：1987-05-01 00:00:00
abstract：INTRODUCTION:Psychotic symptoms in bipolar II disorder, allowed by definition only during a depressive episode, are present in a range between 3% and 45%. Little is known regarding the impact of psychotic symptoms on the clinical course of bipolar II patients. Findings from previous reports are controversial and focuse...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.03.028
更新日期：2010-10-01 00:00:00
