New and evolving therapies for hereditary angioedema.

Abstract:

:Hereditary angioedema (HAE) is a rare, autosomal dominant, genetic disorder associated with a deficiency in C1 inhibitor protein. HAE is characterized by recurrent and unpredictable episodes of swelling of the extremities, abdomen, face, and upper airway. There are several newly approved drugs as well as investigational products that are currently under study for the management of patients with HAE, with the potential to optimize care and improve quality of life for patients with HAE. We reviewed the evolution of HAE treatment options in the United States and discussed mechanisms of action, routes of administration, and efficacy of these therapies.

journal_name

Allergy Asthma Proc

authors

Barmettler S,Li Y,Banerji A

doi

10.2500/aap.2019.40.4195

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

7-13

issue

1

eissn

1088-5412

issn

1539-6304

journal_volume

40

pub_type

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