Management of Pleural Effusion After Mediastinoscopic Radical Esophagectomy.

Abstract:

BACKGROUND/AIM:Trans-hiatal and -cervical approach mediastinoscopic radical esophagectomy (TMrE) for esophageal cancers is a less-invasive procedure and does not require for trans-thoracic approach management. However, some patients suffer from pleural effusion after TMrE. In the present study, we investigated the clinicopathological factors of patients needing drainage of pleural effusion (DPE) after TMrE. PATIENTS AND METHODS:This study included 118 patients who underwent TMrE between 2010 and 2016. RESULTS:There were 43, 34 and 41 patients that underwent none, a single, and two or more DPEs respectively. Left-side DPE was significantly more frequent compared to right-side DPE. Change in the C-reactive protein (CRP) levels after surgery was significantly higher in patients with multiple DPEs than patients with none or a single DPE. The hospitalization days were significantly longer for patients with multiple DPEs. CONCLUSION:Pleural effusion accumulates due to continuous inflammation. Although a temporary DPE is sometimes performed, post-operative chest drainage tubes are not necessarily needed.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Hamada J,Konishi H,Shiozaki A,Fujiwara H,Shoda K,Kosuga T,Kubota T,Okamoto K,Arita T,Morimura R,Murayama Y,Ikoma H,Kuriu Y,Nakanishi M,Otsuji E

doi

10.21873/anticanres.13069

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

6919-6925

issue

12

eissn

0250-7005

issn

1791-7530

pii

38/12/6919

journal_volume

38

pub_type

杂志文章
  • Effect of Fibroblast Growth Factor-2 and its Receptor Gene Polymorphisms on the Survival of Patients With Hepatitis B Virus-associated Hepatocellular Carcinoma.

    abstract:BACKGROUND/AIM:Fibroblast growth factor (FGF), vascular endothelial growth factor, and hepatocyte growth factor play a critical role in the pathogenesis of hepatocellular carcinoma (HCC). MATERIALS AND METHODS:We assessed nine single nucleotide polymorphisms (SNPs) in the FGF1, FGF2, FGF receptor (FGFR)-2, Flt-1, and ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.13337

    authors: Kim SS,Eun JW,Cho HJ,Lee HY,Seo CW,Noh CK,Shin SJ,Lee KM,Cho SW,Cheong JY

    更新日期:2019-04-01 00:00:00

  • Cell-surface expression of complement restriction factors and sialyl Lewis antigens in oral carcinoma: relevance to chemo-immunotherapy.

    abstract::Oral squamous cell carcinomas overexpress tumor-associated antigens, yet these antigens do not induce an immune-mediated anti-tumor response. The absence of an anti-tumor immune response may be due to poor immunogenicity of the tumor antigens or due to presence of factors that restrict immune functions. We have analyz...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Ravindranath NM,Nishimoto K,Chu K,Shuler C

    更新日期:2000-01-01 00:00:00

  • Lysozyme is up-regulated in columnar-lined Barrett's mucosa: a possible natural defence mechanism against Barrett's esophagus-associated pathogenic bacteria.

    abstract:BACKGROUND:Lysozyme is a natural antimicrobial enzyme that is up-regulated in inflammatory diseases of the gastrointestinal tract. Pathogenic microbes have recently been identified in the esophageal mucosa in patients with Barrett's esophagus (BE). Lysozyme expression was evaluated in biopsies from patients with BE. M...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Rubio CA

    更新日期:2012-11-01 00:00:00

  • Nicotine Exposure Augments Renal Toxicity of 5-aza-cytidine Through p66shc: Prevention by Resveratrol.

    abstract:BACKGROUND/AIM:We have shown that either chronic nicotine (NIC) exposure or 5-aza-cytidine (AZA) augments oxidative stress-dependent injury through stimulating p66shc in renal cells. Hence, NIC could exacerbate adverse effects of AZA while antioxidants such as resveratrol (RES) could prevent it. MATERIALS AND METHODS:...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.11793

    authors: Arany I,Hall S,Faisal A,Dixit M

    更新日期:2017-08-01 00:00:00

  • The impact of timing of EGFR and IGF-1R inhibition for sensitizing head and neck cancer to radiation.

    abstract:BACKGROUND:Targeting the epidermal growth factor receptor (EGFR) improved radiotherapy outcome by 10-15% in head and neck tumors (HNSCC). We tested the therapeutic benefits of co-targeting EGFR and insulin-like growth factor-1 receptor (IGF-1R) to further enhance tumor response to radiation. MATERIALS AND METHODS:Mice...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Matsumoto F,Valdecanas DN,Mason KA,Milas L,Ang KK,Raju U

    更新日期:2012-08-01 00:00:00

  • Mechanisms by which chemotherapeutic agents augment the antitumor effects of tumor necrosis factor: involvement of the pattern shift of cytokines from Th2 to Th1 in tumor lesions.

    abstract:BACKGROUND:The antitumor effect exerted by tumor necrosis factor (TNF) is characteristic in that it causes central necrosis of the tumor mass. Viable tumor cells surrounding the tumor mass remain, however, even after most of the mass is necrotized, and these cells gradually regrow and form tumors. To overcome this, we ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Inagawa H,Nishizawa T,Honda T,Nakamoto T,Takagi K,Soma G

    更新日期:1998-09-01 00:00:00

  • A common pathway for chemotherapy-induced apoptosis in human squamous cell carcinoma lines distinct from that of receptor-mediated cell death.

    abstract::Regulation of apoptosis by extracellular molecules binding to cell death receptors has received much attention in recent years. Fas, a member of the tumor necrosis factor receptor superfamily, is a transmembrane protein whose extracellular domain binds its cognate ligand (FasL), which can induce apoptosis in sensitive...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Crowe DL,Yoon E

    更新日期:2003-05-01 00:00:00

  • Effects of flavonoids on the growth and cell cycle of cancer cells.

    abstract::In this study, we investigated the cytotoxicities of flavone (F01), 3-hydroxyflavone (F02), 6- hydroxyflavone (F03), 7-hydroxyflavone (F04), 3,6-dihydroxyflavone (F05), 5,7-dihydroxyflavone (F06) and 5,6,7-trihydroxyflavone (F07) to human cancer cells including P- glycoprotein (Pgp)-expressing HCT15 cells and its mult...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Choi SU,Ryu SY,Yoon SK,Jung NP,Park SH,Kim KH,Choi EJ,Lee CO

    更新日期:1999-11-01 00:00:00

  • Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.

    abstract:BACKGROUND:Dihydroceramide desaturase 1 (DES) is the enzyme responsible for converting dihydroceramide into ceramide in the de novo sphingolipid biosynthesis pathway. Dihydroceramide can inhibit ceramide channel formation to interfere with apoptosis. We have shown that following ceramide synthase knockdown, photodynami...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Breen P,Joseph N,Thompson K,Kraveka JM,Gudz TI,Li L,Rahmaniyan M,Bielawski J,Pierce JS,VAN Buren E,Bhatti G,Separovic D

    更新日期:2013-01-01 00:00:00

  • Selective anticancer activity of neurotoxin 1-methyl-4-phenylpyridinium on non-small cell lung adenocarcinoma A549 cells.

    abstract:BACKGROUND:Lung cancer is the second leading cause of mortality among men and women in the U.S. Among different varieties of lung cancer, the non-small cell lung cancer (NSCLC) has the highest frequency comprising about 85% of cases. We evaluated 1-methyl-4-phenylpyridinium ion (MPP(+)) for cytotoxicity against human l...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Badisa RB,Mina DA,Latinwo LM,Soliman KF

    更新日期:2014-10-01 00:00:00

  • Hyperthermia and verapamil inhibit the growth of human colon cancer xenografts in vivo through apoptosis.

    abstract:BACKGROUND:The long-term goal of this work is to develop a new therapeutic regimen for the treatment of colon cancer in humans which will include hyperthermic intraperitoneal perfusion of verapamil as an alternative to administration of chemotherapy. METHODS AND RESULTS:Hyperthermia and verapamil caused a significant ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Shchepotin IB,McRae DA,Shabahang M,Buras RR,Evans SR

    更新日期:1997-05-01 00:00:00

  • vPARP Adjusts MVP Expression in Drug-resistant Cell Lines in Conjunction with MDR Proteins.

    abstract:BACKGROUND/AIM:The definition of vault (ribonucleoprotein particles) function remains highly complex. Vaults may cooperate with multidrug resistance (MDR) proteins, supporting their role in drug resistance. This topic is the main theme of this publication. MATERIALS AND METHODS:The cell viability was determined by an ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.11656

    authors: Wojtowicz K,Januchowski R,Nowicki M,Zabel M

    更新日期:2017-06-01 00:00:00

  • p53 mutations in colorectal cancers in the patients of Metropolitan New York.

    abstract::An unselected series of 19 colorectal adenocarcinomas obtained from patients treated by surgery at Memorial Sloan-Kettering Cancer Center (MSKCC), New York, USA was investigated for mutations in exons 5, 6, 7 and 8 of the p53 gene. Ten of the tumors revealed at least one somatic mutation either in the exon 5 or 8. Two...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: van den Broek MH,Jhanwar SC,Fodde R,Chaganti RS,Meera Khan PM

    更新日期:1993-09-01 00:00:00

  • Clinical Significance of Glioma-associated Oncogene 1 Expression in Patients With Locally Advanced Gastric Cancer Administered Adjuvant Chemotherapy With S-1 After Curative Surgery.

    abstract:BACKGROUND/AIM:Glioma-associated oncogene 1 (GLI1) is an important transcription factor in the hedgehog signalling pathway and tumour formation. We evaluated the clinical significance of GLI1 expression as a prognostic factor in patients with locally advanced gastric cancer (GC). PATIENTS AND METHODS:GLI1 expression l...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.14599

    authors: Hashimoto I,Oue N,Kimura Y,Hiroshima Y,Hara K,Maezawa Y,Kano K,Fujikawa H,Aoyama T,Numata M,Yamada T,Tamagawa H,Yamamoto N,Ogata T,Shiozawa M,Morinaga S,Rino Y,Yasui W,Masuda M,Miyagi Y,Oshima T

    更新日期:2020-10-01 00:00:00

  • Analysis of 7 immunohistochemical markers in male germ cell tumors demonstrates the prognostic significance of p53 and MIB-1.

    abstract:BACKGROUND:Various prognostic factors have been investigated in order to predict the minority of male germ cell tumor (GCT) patients who will develop resistant disease. However, no prognostic system has been proven accurate. MATERIALS AND METHODS:Paraffin-embedded tissue specimens, obtained from primary lesions during...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Pectasides D,Papaxoinis G,Nikolaou M,Valavanis C,Aravantinos G,Fountzilas G,Tamvakis N,Pectasides E,Lekka I,Arapantoni-Dadioti P,Zizi A,Ghiconti I,Economopoulos T

    更新日期:2009-02-01 00:00:00

  • Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response.

    abstract:BACKGROUND:Intratumoural hypoxia is associated with chemoresistance in glioblastoma multiforme (GBM), a highly malignant brain tumour. Adaptive response to endoplasmic reticulum stress induced by temozolomide is a major obstacle in recurrent GBM. We investigated whether hyperoxia resensitizes temozolomide-resistant GBM...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Lee D,Sun S,Ho AS,Kiang KM,Zhang XQ,Xu FF,Leung GK

    更新日期:2014-06-01 00:00:00

  • Role of Adjuvant Chemotherapy in Pulmonary Carcinoids: An NCDB Analysis.

    abstract:BACKGROUND/AIM:Typical carcinoids (TC) and atypical carcinoids (AC) are rare diseases. A paucity of randomized studies and disagreements among various guidelines makes the management challenging. PATIENTS AND METHODS:Using codes for TC (8240) and AC (8249) in the National Cancer Database (NCDB), all surgically resecte...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.13900

    authors: Gosain R,Groman A,Yendamuri SS,Iyer R,Mukherjee S

    更新日期:2019-12-01 00:00:00

  • Upfront Surgery for Small Intestinal Non-Hodgkin's Lymphoma.

    abstract:BACKGROUND/AIM:The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. PATIENTS AND METHODS:Twenty patients with small intestinal lymphoma who underw...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.14206

    authors: Iida T,Nozawa H,Sonoda H,Toyama K,Kawai K,Hata K,Tanaka T,Nishikawa T,Sasaki K,Shuno Y,Kaneko M,Murono K,Emoto S,Ishii H,Kurokawa M,Ishihara S

    更新日期:2020-04-01 00:00:00

  • Decreased immunoexpression of standard form of CD44 is an independent favourable predictor of nodal metastasis in colorectal carcinoma.

    abstract:BACKGROUND:CD44 is a transmembrane glycoprotein and is associated with cell-matrix and cell-cell interactions. CD44 expression was shown to be relevant to tumour progression in various types of human cancer. The objective of this study was to investigate the relationship between the expression levels of the standard fo...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Al-Maghrabi J,Gomaa W,Buhmeida A,Al-Qahtani M,Al-Ahwal M

    更新日期:2012-08-01 00:00:00

  • Phase II and III studies with new drugs for non-small cell lung cancer: a systematic review of the literature with a methodology quality assessment.

    abstract::We carried out a systematic review of new drugs active in non-small cell lung carcinoma (NSCLC). Fifty five phase II and III trials were reviewed (vinorelbine (19 trials), paclitaxel (15), gemcitabine (11), docetaxel (6), topotecan (2) or irinotecan (2)). The first four ones could be considered as active drugs when gi...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:

    authors: Meert AP,Berghmans T,Branle F,Lemaître F,Mascaux C,Rubesova E,Vermylen P,Paesmans M,Sculier JP

    更新日期:1999-09-01 00:00:00

  • Analytical Methods for Quantification of Vitamin D and Implications for Research and Clinical Practice.

    abstract::A plethora of contradictory research surrounds vitamin D and its influence on health and disease. This may, in part, result from analytical difficulties with regard to measuring vitamin D metabolites in serum. Indeed, variation exists between analytical techniques and assays used for the determination of serum 25-hydr...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:10.21873/anticanres.12332

    authors: Stokes CS,Lammert F,Volmer DA

    更新日期:2018-02-01 00:00:00

  • Efficacy of the progesterone receptor antagonist mifepristone for palliative therapy of patients with a variety of advanced cancer types.

    abstract:BACKGROUND:Mifepristone has been demonstrated to improve longevity and quality of life in mice with spontaneous murine cancer without progesterone receptors and in human colon cancer. The present study evaluated the palliative effect of mifepristone in a variety of different types of human cancer. PATIENTS AND METHODS...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Check JH,Dix E,Cohen R,Check D,Wilson C

    更新日期:2010-02-01 00:00:00

  • Cancer gene therapy: challenges and opportunities.

    abstract::Understanding the molecular basis of human disease has been the corner-stone of rationally designed molecular therapies. Medicine has a long history of treating patients with cell therapies (i.e., blood transfusions) and protein therapies (i.e., growth factors and cytokines). Gene therapies are the newest therapeutic ...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:

    authors: Scanlon KJ

    更新日期:2004-03-01 00:00:00

  • The value of pemetrexed for the treatment of malignant pleural mesothelioma: a comprehensive review.

    abstract::This review aims to provide insight into treatment of malignant pleural mesothelioma (MPM) considering effects on survival, quality of life (QoL) and costs, in order to determine the value of pemetrexed in MPM treatment. Cisplatin in combination with pemetrexed or raltitrexed increased survival in MPM, whereas vinorel...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:

    authors: Boons CC,VAN Tulder MW,Burgers JA,Beckeringh JJ,Wagner C,Hugtenburg JG

    更新日期:2013-09-01 00:00:00

  • The role of regulatory T cells in malignant glioma.

    abstract::The aggressive nature of gliomas is closely related to their capacity to evade the anti-tumoral immune response. The mechanisms implicated in this phenomenon are only partially understood. A subset of T cells, termed CD4+ CD25+ regulatory T cells (Treg), have been shown to inhibit the actions of effector lymphocytes. ...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:

    authors: Sonabend AM,Rolle CE,Lesniak MS

    更新日期:2008-03-01 00:00:00

  • Comparison of glucose-consumption and thymidine-incorporation endpoints in histocultured human superficial bladder tumors.

    abstract::Glucose consumption and tritiated thymidine incorporation were monitored for 54 days in histocultured human superficial transitional cell carcinoma of the bladder, indicating that long-term histoculture of human transitional cell carcinoma of the bladder is feasible. The glucose-consumption rate was relatively similar...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Chang SG,Lee JH,Hong DH,Lee HL,Chai SE,Hoffman RM

    更新日期:1994-01-01 00:00:00

  • Mapping oxidative changes in breast cancer: understanding the basic to reach the clinics.

    abstract::Since long, oxidative stress-driven modifications in breast cancer were faced as detrimental cellular events that cause obligatory cell damage. Recent studies show that the products generated during redox reactions are able to modulate pivotal processes regarding breast cancer survival, proposing a new way of looking ...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:

    authors: Mencalha A,Victorino VJ,Cecchini R,Panis C

    更新日期:2014-03-01 00:00:00

  • CEA, CA 15-3, and TPS as Prognostic Factors in the Follow-up Monitoring of Patients After Radical Surgery for Breast Cancer.

    abstract:AIM:The aim of this study was to evaluate the ability of tissue polypeptide-specific antigen (TPS), carcinoembryonic antigen (CEA), and cancer antigen 15-3 (CA 15-3) to predict relapse in breast cancer patients, when the measurement of biomarkers is performed within 6 months after surgery. PATIENTS AND METHODS:Four hu...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.12245

    authors: Svobodova S,Kucera R,Fiala O,Karlikova M,Narsanska A,Zedníková I,Treska V,Slouka D,Rousarova M,Topolcan O,Finek J

    更新日期:2018-01-01 00:00:00

  • Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6).

    abstract:BACKGROUND:The sonodynamically-induced in vitro and in vivo antitumor effects of mono-l-aspartyl chlorin e6 (NPe6) was investigated. MATERIALS AND METHODS:Both in vitro and in vivo antitumor effects were tested in combination with ultrasound at 2 MHz. RESULTS:The rate of ultrasonically-induced damage on isolated sarc...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Yumita N,Iwase Y,Nishi K,Ikeda T,Komatsu H,Fukai T,Onodera K,Nishi H,Takeda K,Umemura S,Okudaira K,Momose Y

    更新日期:2011-02-01 00:00:00

  • Breast cancer screening by mammography in women aged under 50 years in Japan.

    abstract:BACKGROUND:The effectiveness of mammographic screening in women aged over 50 years has been confirmed in the United States and Europe, but its effectiveness in women aged from 40 to 49 years remains controversial. The optimum age for effective screening of subjects for breast cancer by mammography in Japan was studied ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Morimoto T,Sasa M,Yamaguchi T,Kondo H,Akaiwa H,Sagara Y

    更新日期:2000-09-01 00:00:00