Low dose effects and non-monotonic dose responses for endocrine active chemicals: science to practice workshop: workshop summary.

Abstract:

:A workshop was held in Berlin September 12-14th 2012 to assess the state of the science of the data supporting low dose effects and non-monotonic dose responses ("low dose hypothesis") for chemicals with endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present the current state of the science of EDC action and also the risk assessment process. These lectures were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an open and unbiased manner the data supporting the "low dose hypothesis". While no consensus was reached the robust discussions were helpful to inform both basic scientists and risk assessors on all the issues. There were a number of important ideas developed to help continue the discussion and improve communication over the next few years.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Beausoleil C,Ormsby JN,Gies A,Hass U,Heindel JJ,Holmer ML,Nielsen PJ,Munn S,Schoenfelder G

doi

10.1016/j.chemosphere.2013.06.043

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

847-56

issue

6

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(13)00885-0

journal_volume

93

pub_type

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