Dysphagia and pharmacotherapy in older adults.

abstract：PURPOSE OF REVIEW:To describe the evidences for and against the different nutritional and nonnutritional therapeutic approaches for severe alcoholic steatohepatitis, based on data from randomized controlled trials, in order to answer the question posed in the title: 'more of the same or something new?'. RECENT FINDING...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cabré E

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:L-Arginine is the precursor for nitric oxide synthesis. In the brain, nitric oxide acts as a neurotransmitter; in the immune system, nitric oxide acts as a mediator of host defense; in the cardiovascular system, nitric oxide mediates the protective effects of the intact endothelium, acting as an endog...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Böger RH

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The rapid muscle loss that accompanies varying diseased states (cachexia) is due to an imbalance between muscle protein synthesis (MPS) and muscle protein breakdown In the current review, we will discuss and summarize recent evidence in order to provide practical recommendations on exercise and nutrie...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Breen L,Phillips SM

更新日期：2012-05-01 00:00:00

abstract：:Critical illness and severe injury induce a number of neuroendocrine changes that initially enhance survival. However, for skeletal muscle, the hormonal environment is such that accelerated catabolism predominates. The prevailing hypercortisolemia is exacerbated by a resistance to or decreased production of anabolic h...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent advances in metabolomic tools now permit to characterize dysregulated metabolic pathways in various diseases associated with the identification of sensitive and specific early responding biomarkers that are critical both for the diagnosis of the type of insult as well as for the selection and e...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sébédio JL,Pujos-Guillot E,Ferrara M

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The design and the development of functional foods is a key issue for bone health and a scientific challenge as well. As most studies have focused on calcium, and have paid less attention to other nutrients, our knowledge of the influence of nutrition on bone health remains limited. It has been well a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Davicco MJ,Wittrant Y,Coxam V

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Leucine does not only serve as a substrate for protein synthesis but is also recognized as a potent signal nutrient that regulates protein metabolism. Accordingly, leucine supplementation has been suggested to develop muscle mass or prevent protein loss in several conditions characterized by muscle pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Balage M,Dardevet D

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review aims to address the role of adipose tissue oxygen partial pressure (PO2) in the metabolic and endocrine derangements in conditions characterized by insulin resistance. RECENT FINDINGS:The balance between adipose tissue oxygen supply and its metabolic rate seems to determine adipose...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goossens GH,Blaak EE

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Obese individuals have impaired respiratory function relative to their normal-weight counterparts. Despite these negative effects, obesity is paradoxically associated with better survival in individuals with chronic obstructive pulmonary disease (COPD). The purpose of this review is to describe this '...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Guenette JA,Jensen D,O'Donnell DE

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Berthoud HR

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate whether the diet of lactating women modulates the development of allergic disease in their children. RECENT FINDINGS:Although maternal avoidance of common food protein allergens was previously recommended for lactating women with infants predisposed to allergic disease, recent expert revi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Palmer DJ,Makrides M

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight recent methodological advances that have helped us to understand the role of intramuscular triglycerides in human health as well as prevention and treatment of disease. In addition to both invasive (muscle biopsy) and noninvasive methods, techniques to assess...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dubé J,Goodpaster BH

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is highly prevalent in hospitalized patients. Despite this, it is not routinely assessed in most hospitals worldwide. One of the reasons that might explain this fact is that there is no gold-standard nutritional assessment tool, and much has been written advocating this or that technique....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Waitzberg DL,Correia MI

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition and polypharmacy increase with age and polymorbidity and their relationship is based on a number of mechanisms. The occurrence of malnutrition in both in-patients and out-patients and its dependence on polymorbidity and age are well known, but the interrelation of polypharmacy and malnutr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zadak Z,Hyspler R,Ticha A,Vlcek J

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle and lean body mass may be vital to prognosis and functional recovery in chronic and acute illness, particularly in conditions in which muscle atrophy is prevalent. Ultrasound provides a precise and expedient method to measure muscle mass and changes in skeletal muscle at the bedside. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mourtzakis M,Wischmeyer P

更新日期：2014-09-01 00:00:00

abstract：:Essentially, there have not been any outstanding recent developments in nutritional assessment techniques. However, it would appear that the acceptance that there is no absolute gold standard for nutritional assessment has led to the development of disease specific and clinically relevant subjective global type-assess...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Downs JH,Haffejee A

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipid sources for enteral nutrition continue to be an exciting area of investigation. It is timely to review recent developments which have largely contributed to thrust enteral feeding into a new era. RECENT FINDINGS:Although much more research needs to be done, there is a better understanding of th...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Roy CC,Bouthillier L,Seidman E,Levy E

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Preventing unintentional weight and muscle loss is of crucial importance to maintain the condition and well-being of patients with cancer, improve treatment response and tolerance, and prolong survival. Anabolic resistance might explain why some cancer patients do not respond to nutritional interventi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Engelen MP,van der Meij BS,Deutz NE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:A compromised autophagy is associated with the onset of obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases. Our aim is to review the potential role of ghrelin, a gut hormone involved in energy homeostasis, in the regulation of autophagy. RECENT F...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ezquerro S,Frühbeck G,Rodríguez A

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Muscle protein synthesis (MPS) and muscle protein breakdown are simultaneous ongoing processes. Here, we examine evidence for how protein quality can affect exercise-induced muscle protein anabolism or protein balance (MPS minus muscle protein breakdown). Evidence is highlighted showing differences in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tang JE,Phillips SM

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Glatz JF,Bonen A,Luiken JJ

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Epigenetics has emerged in recent years as one of the most important biological mechanisms linking exposures across the life course to long-term health. This article reviews recent developments in our understanding of the metabolic and genetic determinants of epigenetic variation in human populations....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Haggarty P

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Randomized controlled trials can be difficult to conduct in critically ill patients and may not always be the most appropriate type of study. Cohort studies can provide valuable information in large complete populations of patients without strict exclusion criteria and without the need for informed co...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Vincent JL,Preiser JC

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Intradialytic nutritional support has been used for more than 30 years both in critically ill patients with acute renal failure and during maintenance hemodialysis. Present knowledge allows better estimation of its metabolic and nutritional efficacy, as well its effect on patient outcome. RECENT FIND...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cano NJ,Leverve XM

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to highlight recent research findings that advance our understanding of the relation between iron status and neural functioning. RECENT FINDINGS:Recent findings have helped to answer questions pertaining to the interrelationship of iron and neural functioning in three pri...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Murray-Kolb LE

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the potential benefits of increased dietary protein during weight loss and the importance of distribution of high-quality protein at each meal. RECENT FINDINGS:Popular weight loss diets emphasize use of protein as a substitute for carbohydrates or fat to reduce insulin and minimize hung...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Devkota S,Layman DK

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The term oxidative stress is often used to indicate a condition in which the accumulation of reactive oxygen species is considered just damaging. We will discuss both the physiological and pathological role of oxidative stress on skeletal muscle homeostasis and function, and how oxidative stress can a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Musarò A,Fulle S,Fanò G

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article describes recent findings regarding lipid metabolism in critical illness as well as in lipid therapy. RECENT FINDINGS:In critical illness, in the presence of a decrease in lipid absorption, adipose tissue lipolysis raises triglyceride levels. High-density lipoprotein and low-density lipo...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Green P,Theilla M,Singer P

更新日期：2016-03-01 00:00:00