Abstract:
:Accumulating evidence shows that hyperthermia improves head-and-neck cancer treatment. Over the last decade, we introduced a radiofrequency applicator, named HYPERcollar, which enables local heating also of deep locations in this region. Based on clinical experience, we redesigned the HYPERcollar for improved comfort, reproducibility and operator handling. In the current study, we analyze the redesign from an electromagnetic point of view. We show that a higher number of antennas and their repositioning allow for a substantially improved treatment quality. Combined with the much better reproducibility of the water bolus, this will substantially minimize the risk of underexposure. All improvements combined enable a reduction of hot-spot prominence (hot-spot to target SAR quotient) by 32% at an average of 981 W, which drastically reduces the probability for system power to become a treatment limiting source. Moreover, the power deposited in the target selectively can be increased by more than twofold. Hence, we expect that the HYPERcollar redesign currently under construction allows us to double the clinically applied power to the target while reducing the hot-spots, resulting in higher temperatures and, consequently, better clinical outcome.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Togni P,Rijnen Z,Numan WC,Verhaart RF,Bakker JF,van Rhoon GC,Paulides MMdoi
10.1088/0031-9155/58/17/5997subject
Has Abstractpub_date
2013-09-07 00:00:00pages
5997-6009issue
17eissn
0031-9155issn
1361-6560journal_volume
58pub_type
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