Simultaneous T(1) and B(1) (+) mapping using reference region variable flip angle imaging.


PURPOSE:To present a new method that can simultaneously and efficiently measure T1 and B1 (+) maps using reference region variable flip angle (RR-VFA) imaging. METHODS:Assuming T1 relaxation time in a reference region such as fat is well characterized, and the reference region sufficiently covers smoothly varying B1 (+) field inhomogeneity, B1 (+) maps can be measured from VFA images, conventionally used for T1 measurements. Fat-only images from two-point Dixon acquisitions were used to compute B1 (+) maps, and the B1 (+) maps were compared with ones using the double-angle method (DAM) in 22 breast MRI patients at 3T. Additionally, high spatial resolution VFA images were acquired to show T1 measurements with and without the RR-VFA B1 (+) correction in six patients. RESULTS:RR-VFA is able to generate reliable B1 (+) maps, similar to those using the conventional DAM. This simultaneous T1 and B1 (+) mapping can also be used to reduce T1 estimation errors, where T1 maps have more uniform fibroglandular tissue T1 and better depiction of heterogeneous T1 of breast masses. CONCLUSION:A new method that can measure both T1 and B1 (+) maps based on Dixon VFA images is described, offering improved T1 quantification with no scan time penalty.


Magn Reson Med


Sung K,Saranathan M,Daniel BL,Hargreaves BA




Has Abstract


2013-10-01 00:00:00












  • Analytical solution and verification of diffusion effect in SSFP.

    abstract::Assuming that the SSFP magnetization response maintains a steady state which is periodic in the presence of diffusion, we can solve for the diffusion effect in such sequences. Formulating a Fourier series decomposition solution to the Bloch-Torrey equation and imposing the steady-state condition, analytical expression...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Carney CE,Wong ST,Patz S

    更新日期:1991-06-01 00:00:00

  • A multicontrast imaging method using steady-state free precession with alternating RF flip angles.

    abstract:PURPOSE:To obtain multicontrast images including fat-suppressed contrast image, a novel multicontrast imaging method using an SSFP sequence with alternating RF flip angles is proposed. METHODS:The proposed method uses the balanced SSFP sequence with 2 flip angles. In general, the conventional balanced SSFP sequence ha...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Kim J,Seo H,So S,Park H

    更新日期:2018-10-01 00:00:00

  • Nonbalanced SSFP-based quantitative magnetization transfer imaging.

    abstract::The previously reported concept for quantitative magnetization transfer (MT) imaging using balanced steady-state free precession (SSFP) is applied to nonbalanced SSFP sequences. This offers the possibility to derive quantitative MT parameters of targets with high-susceptibility variations such as the musculoskeletal s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Gloor M,Scheffler K,Bieri O

    更新日期:2010-07-01 00:00:00

  • Uncertainties of calculated Cramér-Rao lower bounds: implications for quantitative MRS.

    abstract:PURPOSE:To investigate the uncertainties on relative Cramér-Rao lower bound (rCRB) estimates and demonstrate their biasing effects in MRS quantification. THEORY AND METHODS:Simulations were performed to calculate the distribution of the computed rCRB (noted rCRB*) for several rCRB levels. One hundred thousand simulati...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Bonny JM,Pagès G

    更新日期:2019-02-01 00:00:00

  • Differential effect of isoflurane, medetomidine, and urethane on BOLD responses to acute levo-tetrahydropalmatine in the rat.

    abstract::Levo-tetrahydropalmatine (l-THP) has shown significant promise in preclinical and clinical studies to treat drug addiction. Pharmacological MRI methods can elucidate the regional cerebral effects of l-THP, but there are potential confounds from the use of general anesthesia. To investigate the possible anesthetic-drug...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Liu X,Li R,Yang Z,Hudetz AG,Li SJ

    更新日期:2012-08-01 00:00:00

  • Strategy for the spectral filtering of myo-inositol and other strongly coupled spins.

    abstract::A multiple quantum filter strategy is presented for spectrally discriminating metabolites with strongly coupled spins from those whose spins are either uncoupled or weakly coupled. The strategy also includes a means for selectively suppressing the background multiplets of metabolites that also have strongly coupled sp...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Kim H,Wild JM,Allen PS

    更新日期:2004-02-01 00:00:00

  • fMRI of auditory stimulation with intermolecular double-quantum coherences (iDQCs) at 1.5T.

    abstract::An intermolecular double-quantum coherence (iDQC) imaging technique was used to study auditory activation in the human brain at 1.5T with a dual temporal lobe surface phased array coil and a quadrature head coil. Preliminary results demonstrate that it is feasible to obtain auditory activation maps using iDQC imaging ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Zhong J,Kwok E,Chen Z

    更新日期:2001-03-01 00:00:00

  • Relayed nuclear Overhauser enhancement imaging with magnetization transfer contrast suppression at 3 T.

    abstract:PURPOSE:To develop a pulsed CEST magnetization-transfer method for rapidly acquiring relayed nuclear Overhauser enhancement (rNOE)-weighted images with magnetic transfer contrast (MTC) suppression at clinical field strength (3 T). METHODS:Using a pulsed CEST magnetization-transfer method with low saturation powers (B1...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Huang J,Han X,Chen L,Xu X,Xu J,Chan KWY

    更新日期:2021-01-01 00:00:00

  • Correction of motion-induced susceptibility artifacts and B0 drift during proton resonance frequency shift-based MR thermometry in the pelvis with background field removal methods.

    abstract:PURPOSE:The linear change of the water proton resonance frequency shift (PRFS) with temperature is used to monitor temperature change based on the temporal difference of image phase. Here, the effect of motion-induced susceptibility artifacts on the phase difference was studied in the context of mild radio frequency hy...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Wu M,Mulder HT,Baron P,Coello E,Menzel MI,van Rhoon GC,Haase A

    更新日期:2020-11-01 00:00:00

  • Fast group matching for MR fingerprinting reconstruction.

    abstract:PURPOSE:MR fingerprinting (MRF) is a technique for quantitative tissue mapping using pseudorandom measurements. To estimate tissue properties such as T1 , T2 , proton density, and B0 , the rapidly acquired data are compared against a large dictionary of Bloch simulations. This matching process can be a very computation...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Cauley SF,Setsompop K,Ma D,Jiang Y,Ye H,Adalsteinsson E,Griswold MA,Wald LL

    更新日期:2015-08-01 00:00:00

  • Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic imaging of water and fat resonances.

    abstract::Echo-planar spectroscopic imaging (EPSI) can be used for fast spectroscopic imaging of water and fat resonances at high resolution to improve structural and functional imaging. Because of the use of oscillating gradients during the free induction decay (FID), spectra obtained with EPSI are often degraded by Nyquist gh...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Du W,Du YP,Fan X,Zamora MA,Karczmar GS

    更新日期:2003-06-01 00:00:00

  • Interventional MR elastography for MRI-guided percutaneous procedures.

    abstract:PURPOSE:MRI-guided thermal ablations require reliable monitoring methods to ensure complete destruction of the diseased tissue while avoiding damage to the surrounding healthy tissue. Based on the fact that thermal ablations result in substantial changes in biomechanical properties, interventional MR elastography (MRE)...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Corbin N,Vappou J,Breton E,Boehler Q,Barbé L,Renaud P,de Mathelin M

    更新日期:2016-03-01 00:00:00

  • Transverse relaxivity of iron oxide nanocrystals clustered in nanoemulsions: Experiment and theory.

    abstract:PURPOSE:To compare experimental transverse relaxivities of iron oxide nanocrystals (IONC) as a function of clustering and magnetic field strength with different theoretical model predictions. THEORY AND METHODS:Well-defined IONC clusters in nanoemulsions (NEs) of which both size and IONC loading could be judiciously t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Hak S,Goa PE,Stenmark S,Bjerkholt FF,Haraldseth O

    更新日期:2015-09-01 00:00:00

  • Robust diffusion tensor imaging by spatiotemporal encoding: Principles and in vivo demonstrations.

    abstract:PURPOSE:Evaluate the usefulness of single-shot and of interleaved spatiotemporally encoded (SPEN) methods to perform diffusion tensor imaging (DTI) under various preclinical and clinical settings. METHODS:A formalism for analyzing SPEN DTI data is presented, tailored to account for the spatially dependent b-matrix wei...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Solomon E,Liberman G,Nissan N,Frydman L

    更新日期:2017-03-01 00:00:00

  • Interindividual reproducibility of glutamate quantification using 1.5-T proton magnetic resonance spectroscopy.

    abstract::The goal of this study was to measure the interindividual reproducibility of glutamate quantification in 1.5-T (1)H MRS of human brains. To determine the effective echo time (TE) for glutamate quantification, spectra from a phantom and 12 participants were obtained with TE = 30, 35, 40, and 144 ms (repetition time (TR...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Jang DP,Lee JM,Lee E,Park S,Kim JJ,Namkoong K,Yoon KJ,Kim IY,Kim SI

    更新日期:2005-03-01 00:00:00

  • Motion corrected water/fat whole-heart coronary MR angiography with 100% respiratory efficiency.

    abstract:PURPOSE:To develop a framework for respiratory motion-corrected 3D whole-heart water/fat coronary MR angiography (CMRA) at 3T with reduced and predictable scan time. METHODS:A 3D dual-echo acquisition and respiratory motion-corrected reconstruction framework for water/fat CMRA imaging was developed. The acquisition se...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Munoz C,Cruz G,Neji R,Botnar RM,Prieto C

    更新日期:2019-08-01 00:00:00

  • Parallel reconstruction in accelerated multivoxel MR spectroscopy.

    abstract:PURPOSE:To develop the simultaneous acquisition of multiple voxels in localized MR spectroscopy (MRS) using sensitivity encoding, allowing reduced total scan time compared to conventional sequential single voxel (SV) acquisition methods. METHODS:Dual volume localization was used to simultaneously excite voxels in both...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Boer VO,Klomp DW,Laterra J,Barker PB

    更新日期:2015-09-01 00:00:00

  • DeepCEST: 9.4 T Chemical exchange saturation transfer MRI contrast predicted from 3 T data - a proof of concept study.

    abstract:PURPOSE:To determine the feasibility of employing the prior knowledge of well-separated chemical exchange saturation transfer (CEST) signals in the 9.4 T Z-spectrum to separate overlapping CEST signals acquired at 3 T, using a deep learning approach trained with 3 T and 9.4 T CEST spectral data from brains of the same ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Zaiss M,Deshmane A,Schuppert M,Herz K,Glang F,Ehses P,Lindig T,Bender B,Ernemann U,Scheffler K

    更新日期:2019-06-01 00:00:00

  • A new susceptibility-weighted image reconstruction method for the reduction of background phase artifacts.

    abstract:PURPOSE:To significantly reduce the background phase effects, especially at the air-tissue interface, and to enhance the desirable local structures of veins in susceptibility-weighted imaging. METHODS:In the proposed reconstruction method called Magnitude of Complex Filtering, a complex-valued magnetic resonance image...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Lee Y,Han Y,Park H

    更新日期:2014-03-01 00:00:00

  • Dynamic imaging with multiple resolutions along phase-encode and slice-select dimensions.

    abstract::An implementation is reported of an imaging method to obtain MUltiple Resolutions along Phase-encode and Slice-select dimensions (MURPS), which enables dynamic imaging of focal changes using a graded, multiresolution approach. MURPS allows one to trade spatial resolution in part of the volume for improved temporal res...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Panych LP,Zhao L,Jolesz FA,Mulkern RV

    更新日期:2001-06-01 00:00:00

  • A one-step biomarker quantification methodology for DCE-MRI of adnexal masses: Capturing kinetic pattern from early to late enhancement.

    abstract:PURPOSE:To develop a one-step quantification approach that accounts for joint preprocessing and quantification of whole-range kinetics (early and late-phase washout) of dynamic contrast-enhanced (DCE) MRI of indeterminate adnexal masses. METHODS:Preoperative DCE-MRI of 43 (24 benign, 19 malignant) sonographically inde...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Fathi Kazerooni A,Nabil M,Haghighat Khah H,Parviz S,Gity M,Saligheh Rad H

    更新日期:2018-02-01 00:00:00

  • Abnormal brain anatomical topological organization of the cognitive-emotional and the frontoparietal circuitry in major depressive disorder.

    abstract:PURPOSE:Despite the increasing understanding of major depressive disorder (MDD) using neuroimaging techniques, the topological organization of anatomical networks underlying MDD remains unclear. METHODS:The topological organization of brain anatomical networks was explored using complex network approaches. Diffusion t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Qin J,Wei M,Liu H,Yan R,Luo G,Yao Z,Lu Q

    更新日期:2014-11-01 00:00:00

  • Dynamic 13C NMR analysis of pyruvate and lactate oxidation in the in vivo canine myocardium: evidence of reduced utilization with increased work.

    abstract::In this work, substrate selection was monitored in the left ventricle of the canine myocardium by following pyruvate and lactate oxidation under in vivo conditions at basal and elevated workloads. These studies were conducted in the open chest model using dynamic 13C NMR techniques in the presence and absence of dichl...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Rath DP,Zhu H,Tong X,Jiang Z,Hamlin RL,Robitaille PM

    更新日期:1997-12-01 00:00:00

  • A 7Li NMR study of visibility, spin relaxation, and transport in normal human erythrocytes.

    abstract::The behavior of the lithium (Li) ion in normal human erythrocytes has been studied by 7Li NMR. The uptake of Li into the cells was followed as a function of solution conditions, temperature, hematocrit, and blood age using dysprosium tripolyphosphate shift reagent. Under our conditions the uptake of Li increases with ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Gullapalli RP,Hawk RM,Komoroski RA

    更新日期:1991-08-01 00:00:00

  • A statistical approach to SENSE regularization with arbitrary k-space trajectories.

    abstract::SENSE reconstruction suffers from an ill-conditioning problem, which increasingly lowers the signal-to-noise ratio (SNR) as the reduction factor increases. Ill-conditioning also degrades the convergence behavior of iterative conjugate gradient reconstructions for arbitrary trajectories. Regularization techniques are o...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Ying L,Liu B,Steckner MC,Wu G,Wu M,Li SJ

    更新日期:2008-08-01 00:00:00

  • Tissue characterization and assessment of preoperative chemotherapeutic response in musculoskeletal tumors by in vivo 31P magnetic resonance spectroscopy.

    abstract::This study investigates the potential of in vivo 31P magnetic resonance spectroscopy (MRS) to characterize musculoskeletal tumors and to determine preoperative levels of histological necrosis, which is an important clinical indicator of patient response. Pretherapy MRS was performed on 28 patients with large musculosk...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Redmond OM,Bell E,Stack JP,Dervan PA,Carney DN,Hurson B,Ennis JT

    更新日期:1992-10-01 00:00:00

  • Sensitivity profiles from an array of coils for encoding and reconstruction in parallel (SPACE RIP).

    abstract::A new parallel imaging technique was implemented which can result in reduced image acquisition times in MRI. MR data is acquired in parallel using an array of receiver coils and then reconstructed simultaneously with multiple processors. The method requires the initial estimation of the 2D sensitivity profile of each ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Kyriakos WE,Panych LP,Kacher DF,Westin CF,Bao SM,Mulkern RV,Jolesz FA

    更新日期:2000-08-01 00:00:00

  • Improved sampling of myocardial motion with variable separation tagging.

    abstract::A novel tagging method is introduced that increases the spatial resolution of estimates of myocardial radial thickening. The separation of adjacent parallel tag planes is customized to match the expected motion of specific regions of the heart wall. In regions in which the tags increase their separation over systole (...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: McVeigh ER,Bolster BD Jr

    更新日期:1998-04-01 00:00:00

  • Prospective GIRF-based RF phase cycling to reduce eddy current-induced steady-state disruption in bSSFP imaging.

    abstract:PURPOSE:To propose an explicit Balanced steady-state free precession (bSSFP) signal model that predicts eddy current-induced steady-state disruptions and to provide a prospective, practical, and general eddy current compensation method. THEORY AND METHODS:Gradient impulse response functions (GIRF) were used to simulat...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Bruijnen T,Stemkens B,van den Berg CAT,Tijssen RHN

    更新日期:2020-07-01 00:00:00

  • Intersubject specific absorption rate variability analysis through construction of 23 realistic body models for prostate imaging at 7T.

    abstract:PURPOSE:For ultrahigh field (UHF) MRI, the expected local specific absorption rate (SAR) distribution is usually calculated by numerical simulations using a limited number of generic body models and adding a safety margin to take into account intersubject variability. Assessment of this variability with a large model d...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章


    authors: Meliadò EF,van den Berg CAT,Luijten PR,Raaijmakers AJE

    更新日期:2019-03-01 00:00:00