Abstract:
AIM:To compare combined 2-[18F]-fluoro-2-deoxy-d-glucose (FDG)-positron-emission tomography (PET) and cardiac magnetic resonance imaging (CMR) for the diagnosis and therapy monitoring of cardiac sarcoidosis (CS). MATERIALS AND METHODS:Eighty patients with sarcoidosis and a suspicion of CS who underwent PET and CMR were included retrospectively. PET was undertaken after a low-carbohydrate-high-fat diet in all patients using a combined 16-section PET/computed tomography (CT) camera. PET was considered positive (PET+) in cases of focal or multifocal FDG uptake. CMR was considered positive (CMR+) in cases of subepicardial late gadolinium enhancement (LGE). A subgroup of 50 patients (50/80) was monitored during therapy and classified as responders or non-responders. RESULTS:Eighty-two percent of patients with PET+ (9/11) also had CMR+ imaging, with good spatial agreement (kappa=0,79; 95% confidence interval [CI]: 0.65-0.94). Twenty-seven percent (22/80) had residual physiological FDG uptake, with a standardised uptake value (SUV) not significantly different compared to the SUV from pathological uptake (6.4 versus 6 respectively, p=0,92). The clinical response was more frequent in patients with baseline PET+ compared to baseline PET- (80% versus 45%, p=0.07). PET findings improved in all cases under treatment (7/7), whereas LGE improved in only 33% of patients (3/9). CONCLUSION:Due to high risk of false-positive or undetermined findings, PET might be performed as a second-line study in cases of LGE, to assess inflammatory load. In addition, PET seems suitable to predict and assess response under therapy.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Sgard B,Brillet PY,Bouvry D,Djelbani S,Nunes H,Meune C,Valeyre D,Soussan Mdoi
10.1016/j.crad.2018.09.015subject
Has Abstractpub_date
2019-01-01 00:00:00pages
81.e9-81.e18issue
1eissn
0009-9260issn
1365-229Xpii
S0009-9260(18)30552-Xjournal_volume
74pub_type
杂志文章abstract::We report the ante-natal diagnosis of a vein of Galen aneurysm using colour flow Doppler at 33 weeks gestation. Ultrasound demonstrated a midline, tubular, echo-free structure superior to the thalamus extending posteriorly. Venous flow was demonstrated within the structure using colour flow Doppler. The diagnosis was ...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(05)80200-4
更新日期:1991-10-01 00:00:00
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journal_title:Clinical radiology
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journal_title:Clinical radiology
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abstract:AIM:To determine whether the active involvement of radiographers in nasogastric tube (NGT) management at a large multisite healthcare institution can contribute to risk reduction regarding feeding through misplaced NGTs. MATERIALS AND METHODS:Despite national guidance in the National Health Service advising on safe pr...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(84)80066-5
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abstract::A postal survey of 150 radiologists within the West Midlands Regional Health Authority was undertaken to obtain information about hepatitis B vaccination uptake and its relationship, if any, to their involvement in interventional radiology. Overall, 64% were vaccinated, the rate being higher amongst trainees (81%). No...
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(96)80005-5
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doi:10.1016/s0009-9260(05)81933-6
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doi:10.1016/s0009-9260(89)80135-7
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pub_type: 杂志文章,meta分析,评审
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80860-8
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(05)83143-5
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journal_title:Clinical radiology
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journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
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