Evaluation of FDG PET combined with cardiac MRI for the diagnosis and therapeutic monitoring of cardiac sarcoidosis.


AIM:To compare combined 2-[18F]-fluoro-2-deoxy-d-glucose (FDG)-positron-emission tomography (PET) and cardiac magnetic resonance imaging (CMR) for the diagnosis and therapy monitoring of cardiac sarcoidosis (CS). MATERIALS AND METHODS:Eighty patients with sarcoidosis and a suspicion of CS who underwent PET and CMR were included retrospectively. PET was undertaken after a low-carbohydrate-high-fat diet in all patients using a combined 16-section PET/computed tomography (CT) camera. PET was considered positive (PET+) in cases of focal or multifocal FDG uptake. CMR was considered positive (CMR+) in cases of subepicardial late gadolinium enhancement (LGE). A subgroup of 50 patients (50/80) was monitored during therapy and classified as responders or non-responders. RESULTS:Eighty-two percent of patients with PET+ (9/11) also had CMR+ imaging, with good spatial agreement (kappa=0,79; 95% confidence interval [CI]: 0.65-0.94). Twenty-seven percent (22/80) had residual physiological FDG uptake, with a standardised uptake value (SUV) not significantly different compared to the SUV from pathological uptake (6.4 versus 6 respectively, p=0,92). The clinical response was more frequent in patients with baseline PET+ compared to baseline PET- (80% versus 45%, p=0.07). PET findings improved in all cases under treatment (7/7), whereas LGE improved in only 33% of patients (3/9). CONCLUSION:Due to high risk of false-positive or undetermined findings, PET might be performed as a second-line study in cases of LGE, to assess inflammatory load. In addition, PET seems suitable to predict and assess response under therapy.


Clin Radiol


Clinical radiology


Sgard B,Brillet PY,Bouvry D,Djelbani S,Nunes H,Meune C,Valeyre D,Soussan M




Has Abstract


2019-01-01 00:00:00














  • Rheumatoid arthritis of the crico-arytenoid and crico-thyroid joints: a radiological and clinical study.

    abstract::Low-voltage neck radiography and indirect laryngoscopy was performed in 22 randomly selected rheumatoid patients with the purpose of detecting intralaryngeal arthritis. Radiographic evidence of erosive arthritis of the crico-arytenoid (CA) joints was found in 45% of the patients. Clinical acute CA arthritis without er...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Jurik AG,Pedersen U

    更新日期:1984-05-01 00:00:00

  • Incidental breast masses detected by computed tomography: are any imaging features predictive of malignancy?

    abstract:AIM:To review the outcome of further assessment of breast abnormalities detected incidentally by multidetector computed tomography (MDCT) and to determine whether any MDCT imaging features were predictive of malignancy. MATERIAL AND METHODS:The outcome of 34 patients referred to the Primrose Breast Care Unit with brea...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Porter G,Steel J,Paisley K,Watkins R,Holgate C

    更新日期:2009-05-01 00:00:00

  • Breast MRI artefacts: evaluation and solutions in 630 consecutive patients.

    abstract:AIM:To evaluate the problems that may arise in breast magnetic resonance imaging (MRI) related to the presence of artefacts and pitfalls, in order to improve its accuracy, sensitivity, and specificity. MATERIALS AND METHODS:Six hundred and thirty breast MRI examinations performed using a 1.5 T magnet were analysed ret...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Fiaschetti V,Pistolese CA,Funel V,Rascioni M,Claroni G,Della Gatta F,Cossu E,Perretta T,Simonetti G

    更新日期:2013-11-01 00:00:00

  • Case report: torsion of the gall-bladder on ultrasound--differentiation from acalculous cholecystitis.

    abstract::Acalculous cholecystitis is usually seen in critically-ill patients while torsion of the gall-bladder tends to arise de novo, pre-disposed to by an absent mesentery. There are ultrasonic features in common but the most useful distinguishing finding is the sign of the 'floating gall-bladder'. A case is reported and the...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Cameron EW,Beale TJ,Pearson RH

    更新日期:1993-04-01 00:00:00

  • Pulmonary blood volume imaging with dual-energy computed tomography: spectrum of findings.

    abstract::Dual-energy (DE) pulmonary blood volume (PBV) computed tomography (CT) has recently become available on clinical CT systems. The underlying physical principle of DECT is the fact that the photoelectric effect is strongly dependent on the CT energies resulting in different degrees of x-ray attenuation for different mat...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Hagspiel KD,Flors L,Housseini AM,Phull A,Ali Ahmad E,Bozlar U,Norton PT,Bonatti HJ

    更新日期:2012-01-01 00:00:00

  • How confident are general practitioners in interpreting neuroradiology reports?

    abstract:AIM:To determine the level of confidence general practitioners (GPs) have in radiology reports provided by neuroradiologists and to elicit the preferences of GPs regarding report format and level of detail. MATERIALS AND METHODS:Electronic surveys comprising anonymised neuroradiology reports were sent to GP practices ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Currie S,Saunders D,Khoshneviszadeh S,Craven I

    更新日期:2018-11-01 00:00:00

  • The lymphocyte response in Hodgkin's disease.

    abstract::Fifty cases of Hodgkin's disease have been investigated using the lymphocyte transformation response to phytohaemagglutinin (PHA) as a mesure of their immunological reaction. The average response of all the cases was lower than that of the controls and lower than that of cases of carcinoma from all sites. Cases of Hod...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Braeman J,Evans IH,Deeley TJ

    更新日期:1975-07-01 00:00:00

  • Current and potential renal applications of contrast-enhanced ultrasound.

    abstract::The combination of microbubble technology and complementary ultrasound techniques has resulted in the development of contrast-enhanced ultrasound (CEUS) and, although initial clinical applications largely focussed on the liver, these are now becoming more diverse. With regard to the kidney, it is a safe, well-tolerate...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: McArthur C,Baxter GM

    更新日期:2012-09-01 00:00:00

  • Iopamidol in the diagnosis of suspected upper gastro-intestinal perforation.

    abstract::Forty patients, mainly post-operative, were examined for suspected leakage from the oesophagus and/or stomach using iopamidol. Oesophageal leaks were demonstrated in seven patients, tracheo-oesophageal fistulae in two and an unsuspected gastro-jejunostomy intusussception in one. Only two cases were regarded as technic...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Bell KE,McKinstry CS,Mills JO

    更新日期:1987-03-01 00:00:00

  • The impact of computed tomography on the management of testicular teratoma.

    abstract::A comparison has been undertaken between conventional radiographic imaging and computed tomography (CT) in 35 patients with testicular teratoma as part of an audit of our investigative approach to staging and follow-up. The CT examination included alternate cuts from the carina of the trachea to the lung bases as the ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Chisholm EM,Shiels RA,Jones WG,Robinson PJ

    更新日期:1984-11-01 00:00:00

  • The most useful cranial ultrasound predictor of neurodevelopmental outcome at 2 years for preterm infants.

    abstract:AIM:To determine the most important cranial ultrasound predictors of abnormality associated with neurodevelopmental outcome at 2 years of age in preterm infants. MATERIALS AND METHODS:A total of 343 preterm infants born between 2005 and 2010 and cared for in KK Women's and Children's Hospital, a tertiary paediatric ho...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Hou W,Tang PH,Agarwal P

    更新日期:2020-04-01 00:00:00

  • Craniosynostosis.

    abstract::Craniosynostosis, caused by premature fusion of the sutures, may be syndromic or non-syndromic. Radiology has an important role to play in the assessment, management and follow-up of these patients. Initial investigations may often be undertaken within general radiology departments. An understanding of the terminology...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Aviv RI,Rodger E,Hall CM

    更新日期:2002-02-01 00:00:00

  • Spectrum of imaging findings on axial T2-weighted fat-saturated imaging of the lumbar spine.

    abstract::Axial T2-weighted fat-saturated imaging provides information not readily available from routine lumbar spine magnetic resonance imaging (MRI) protocols and routine inclusion of this sequence in place of axial T1-weighted imaging provides additional diagnostic information that can be obtained without increasing examina...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Csillag A,Ly J

    更新日期:2014-09-01 00:00:00

  • Comparison of image quality and lens dose in helical and sequentially acquired head CT.

    abstract:AIM:To prospectively compare helical and traditional sequential acquisition of computed tomography (CT) images of the head with respect to lens dose, thyroid dose, and image quality. MATERIALS AND METHODS:Patients undergoing non-emergency unenhanced CT examinations of the head were prospectively randomized to sequenti...

    journal_title:Clinical radiology

    pub_type: 杂志文章,随机对照试验


    authors: Abdeen N,Chakraborty S,Nguyen T,dos Santos MP,Donaldson M,Heddon G,Schwarz BA

    更新日期:2010-11-01 00:00:00

  • Experiences with grey scale ultrasonography in hepatic amoebiasis.

    abstract::Ultrasound examination was conducted in 151 proven cases of amoebic liver abscess. In the majority of patients the lesion was solitary but 25% of patients had multiple lesions; 17% of all the abscesses were in the left lobe of the liver. Most abscesses had no, or very few internal echoes and these were either of the s...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Boultbee JE,Simjee AE,Rooknoodeen F,Engelbrecht HE

    更新日期:1979-11-01 00:00:00

  • Transvenous liver biopsy via the femoral vein.

    abstract:AIM:To study the safety, effectiveness and diagnostic value of transvenous forceps biopsy of the liver in 54 patients with coagulopathy, gross ascites or morbid obesity and suspected liver disease in whom percutaneous liver biopsy was contraindicated. MATERIAL AND METHODS:Forceps biopsy of the liver via the femoral ve...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Khosa F,McNulty JG,Hickey N,O'Brien P,Tobin A,Noonan N,Ryan B,Keeling PW,Kelleher DP,McDonald GS

    更新日期:2003-06-01 00:00:00

  • Gigantiform cementoma occurring in two populations, London and Hong Kong.

    abstract::The gigantiform cementoma presents as multiple opacities in the tooth-bearing areas of the jaws. Sixteen cases are presented, six of British Negresses and 10 of Hong Kong Chinese females. The differential diagnosis and management are briefly reviewed. ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: MacDonald-Jankowski DS

    更新日期:1992-05-01 00:00:00

  • Determining the minimal interval between cleansing water enema and double-contrast barium enema examination.

    abstract::In a prospective study 59 consecutive outpatients having double-contrast barium enemas (DCBE) were randomised into four groups. Each group had their enema performed at either a 15, 30, 45 or 60 minute interval following the end of a 1.5 litre cleansing water enema. Review of the films by two radiologists demonstrated ...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lee SH,Bartram CI

    更新日期:1990-05-01 00:00:00

  • Follow-up interval for small untreated pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia.

    abstract:AIM:To investigate the natural history of untreated small (<3 mm) and microscopic pulmonary arteriovenous malformations (PAVMs) in hereditary haemorrhagic telangiectasia (HHT) in order to discern the optimal frequency of follow-up thoracic computed tomography (CT). MATERIALS AND METHODS:A retrospective analysis was pe...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Ryan DJ,O'Connor TM,Murphy MM,Brady AP

    更新日期:2017-03-01 00:00:00

  • The diagnostic value of colour Doppler ultrasound in central venous catheter related thrombosis.

    abstract:AIM:This prospective study was performed to establish the correlation between colour Doppler ultrasound (US) observations and venography in detecting catheter-related thrombosis. METHOD:Forty-four patients with subclavian venous catheters were studied. The sensitivity and specificity of colour Doppler US was determine...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Köksoy C,Kuzu A,Kutlay J,Erden I,Ozcan H,Ergîn K

    更新日期:1995-10-01 00:00:00

  • Standard of the descending (basal) pulmonary artery in children from the routine chest radiograph.

    abstract::The right and left basal artery have been measured in serial radiographs taken annually for 3 years or more, in 48 boys and 45 girls, all clinically normal. Centiles were constructed from 5 to 15 year old children. A study of the gain in size revealed a growth spurt during the pubertal period corresponding to that see...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Simon G,Rona R

    更新日期:1976-10-01 00:00:00

  • Sonographic demonstration of septicaemia with gas-forming organisms after liver transplantation.

    abstract::Sepsis with gas-forming organisms, e.g. Clostridium perfringens and anaerobic streptococci occurred in three of 120 liver-transplant recipients (2.5%). The diagnosis was made in all three patients by bedside ultrasound, before blood cultures revealed bacterial growth. Floating high amplitude echoes within the extra- a...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Jantsch H,Barton P,Függer R,Lechner G,Graninger W,Waneck R,Winkler M

    更新日期:1991-06-01 00:00:00

  • A survey of follow-up practice of urologists across Britain and Ireland following nephrectomy for renal cell carcinoma.

    abstract:AIM:To determine the follow-up protocol for interval assessment of patients following radical nephrectomy for renal cell cancer and to compare them with the recommendations proposed in the literature. METHODS:Consultant urologists across Britain and Ireland completed a postal questionnaire. One follow-up mailing was u...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Basu S,Biyani CS,Sundaram SK,Spencer J

    更新日期:2006-10-01 00:00:00

  • Post-mortem CT: is coronary angiography required in the presence of a high coronary artery calcium score?

    abstract:AIM:To test whether a high coronary artery score predicts that the subsequent post-mortem computed tomography (PMCT) with angiography (PMCTA) will diagnose significant coronary artery disease (CAD); to test the diagnostic impact of assuming there is significant CAD based on a high coronary artery calcium (CAC) score al...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Robinson C,Deshpande A,Rutty G,Morgan B

    更新日期:2019-12-01 00:00:00

  • HRCT findings of collagen vascular disease-related interstitial pneumonia (CVD-IP): a comparative study among individual underlying diseases.

    abstract:AIM:To identify characteristic high-resolution computed tomography (CT) findings for individual collagen vascular disease (CVD)-related interstitial pneumonias (IPs). MATERIALS AND METHODS:The HRCT findings of 187 patients with CVD, including 55 patients with rheumatoid arthritis (RA), 50 with systemic sclerosis (SSc)...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Tanaka N,Kunihiro Y,Kubo M,Kawano R,Oishi K,Ueda K,Gondo T

    更新日期:2018-09-01 00:00:00

  • An efficacy and safety comparison between different stentriever designs in acute ischaemic stroke: a systematic review and meta-analysis.

    abstract:AIM:To assess the recanalisation rates and long-term functional outcomes of the Solitaire and Trevo devices; to compare these results to those from the Solitaire With the Intention For Thrombectomy (SWIFT) trial and TREVO 2 studies; and to assess for statistical differences in the outcomes between the two devices. MAT...

    journal_title:Clinical radiology

    pub_type: 杂志文章,meta分析,评审


    authors: Grech R,Pullicino R,Thornton J,Downer J

    更新日期:2016-01-01 00:00:00

  • The value of urethrocystography in the investigation of patients with spinal cord injury.

    abstract::In a review of 127 urethrocystograms carried out on 92 males with spinal cord injury the following conclusions were drawn. (1) In the presence of vesico-ureteric reflux or urethral reflux into the male adnexa, bladder outlet obstruction should be suspected. (2) Lesions of the anterior urethra develop easily as the res...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Ruutu M,Kivisaari A,Lehtonen T

    更新日期:1984-11-01 00:00:00

  • Clinically unsuspected pulmonary embolism--an important secondary finding in oncology CT.

    abstract:AIM:To determine the rate of finding incidental pulmonary embolisms (PE) at staging or follow-up chest computed tomography (CT) in oncology patients. MATERIALS AND METHODS:Three hundred and eighty-five consecutive chest CT examinations, performed in patients with cancer, were prospectively assessed during a 9-month pe...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Sebastian AJ,Paddon AJ

    更新日期:2006-01-01 00:00:00

  • Strictures and other late complications of neonatal necrotising enterocolitis.

    abstract::Eighty infants have been treated for neonatal necrotising enterocolitis within a period of five years. Twenty-five per cent developed strictures of the small or large intestine. Four cases of atresia including two with multiple cyst formation were seen. Four patients developed severe malabsorption requiring hyperalime...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Virjee JP,Gill GJ,Desa D,Somers S,Stevenson GW

    更新日期:1979-01-01 00:00:00

  • The clinical effectiveness of the Gianturco oesophageal stent in malignant oesophageal obstruction.

    abstract::Between January 1994 and December 1996 72 patients were treated with 76 Gianturco oesophageal stents for oesophageal obstruction or perforation. The patients were followed prospectively in order to determine the effectiveness in improving dysphagia, to establish long term patency, survival times and complications. The...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章


    authors: Laasch HU,Nicholson DA,Kay CL,Attwood S,Bancewicz J

    更新日期:1998-09-01 00:00:00