Abstract：
OBJECTIVES:Rhodiola rosea extract is one of the most common herbal treatment for stress. Its mechanism of action in humans still need to be determined. We investigated the effect of a single dose intake of Rhodiola rosea extract on the plastic after-effects induced by anodal and cathodal motor cortex transcranial Direct Current Stimulation in humans. METHODS:Twenty-eight healthy volunteers were required to intake 500 mg of either RRE or placebo. Transcranial Magnetic Stimulation was used to investigate cortical excitability. Motor threshold, recruitment of motor-evoked potentials, cortical silent period, short-interval intracortical inhibition and intracortical facilitation were assessed at different time points. Spinal excitability and peripheral nerve conduction were measured by F-response and M-wave. Furthermore, we assessed the modulation of cortical plasticity using transcranial direct current stimulation after-effects on Motor Evoked Potentials amplitudes. RESULTS:Rhodiola rosea extract acute intake prevented cathodal transcranial Direct Current Stimulation-induced Long-term depression-like plasticity. The extract intake did not affect cortical excitability. CONCLUSIONS:Our findings suggest that a single oral dose of Rhodiola rosea extract intake modulates cortical plasticity in humans preventing the activity-dependent reduction in the efficacy of neuronal synapses. These results suggest that the adaptogenic and antidepressant effects of Rhodiola rosea extract might be based on its modulation of brain plasticity.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Concerto C,Infortuna C,Muscatello MRA,Bruno A,Zoccali R,Chusid E,Aguglia E,Battaglia Fdoi
10.1016/j.ctim.2018.09.013subject
Has Abstractpub_date
2018-12-01 00:00:00pages
141-146eissn
0965-2299issn
1873-6963pii
S0965-2299(18)30746-5journal_volume
41pub_type
杂志文章abstract：OBJECTIVE:To investigate how individuals expressed rationales for their beliefs regarding efficacy of acupuncture. METHODS:Qualitative data from participants of two different randomized sham-controlled trials, of relaxing (non-cancer volunteers of the general population) or antiemetic (patients with cancer undergoing ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2018.04.006
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to a) investigate the headache features and level of headache severity, chronicity, and disability found within a chiropractic patient population and b) to ascertain if patient satisfaction with headache management by chiropractors is associated with headache group or reason for cons...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.102276
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:Idiopathic Environmental Intolerance (IEI) is an acquired disorder with multiple recurrent symptoms, which is associated with diverse environmental factors that are tolerated by the majority of people. IEI is an illness of uncertain aetiology, making it difficult to treat using conventional medicine. Therefo...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2012.07.005
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVES:To examine whether U.S.-based professional complementary and alternative medicine (CAM) organizations have explicit informed consent policies. DESIGN AND SETTING:Phone survey conducted in July-August 2003. RESULTS:Data were obtained from 37 out of a total of 39 eligible and accessible organizations represe...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2005.03.004
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVES:This pilot study analyses the effect and feasibility of hydrotherapeutic Kneipp arm affusions on secretory immunoglobulin A (sIgA) and classic cold symptoms in children 3-6 years of age. STUDY DESIGN:A controlled, non-randomized, clinical pilot study was undertaken. INTERVENTION:This descriptive hydrothera...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2020.102637
更新日期：2020-11-28 00:00:00
abstract：PURPOSE:The aim of present study was to review and categorize the clinical trials investigating the clinical effects of different botanical parts of dates compared with any controls. METHODS:All clinical trials (randomized, pilot, quasi-experimental, cross-over. and non-randomized clinical trials) evaluating the clini...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2020.102429
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:The importance of mind-body oriented therapies in oncology has increased in recent years. Eurythmy therapy (EYT, Greek: eurythmy=harmonious rhythm) is a mind-body oriented therapy used in Anthroposophic Medicine. EYT can lead to long-term alleviation of chronic disease symptoms and improve patient quality of...
journal_title：Complementary therapies in medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ctim.2008.09.005
更新日期：2009-06-01 00:00:00
abstract：:This brief lifestyle intervention, including a vegan diet rich in fresh fruits and vegetables, whole grains and various legumes, nuts and seeds, significantly improved health risk factors and reduced systemic inflammation as measured by circulating CRP. The degree of improvement was associated with baseline CRP such t...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2014.11.001
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinical effect of Traditional Chinese Spinal Orthopedic Manipulation (TCSOM) in treating Functional Abdominal Pain Syndrome (FAPS) in comparison with Pinaverium Bromide (Dicetel, PBD), and to assess a possible cause for FAPS. METHODS:60 cases of FAPS patients were randomly assigned to the TC...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2017.03.009
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND AND AIM:Descriptive and experimental evaluations of cancer support services require an outcome questionnaire that is valid, responsive to change, feasible and interpretable. This paper describes the development of such a tool. DEVELOPMENT OF THE QUESTIONNAIRE:A validated individualised measure MYMOP was ada...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ctim.2006.03.006
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Gamat (sea-cucumber) is a natural occurring fauna which is popularly used as traditional medication in Southeast Asian countries. There have been many animal studies done on its' biochemical properties and its' effects in vivo. The effect of gamat on human cutaneous wounds was studied using a split-skin graf...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2018.10.006
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Although clinical trials are needed to evaluate the efficacy of liquid herbal medicinal products, design of feasible placebos that mimic the appearance, taste, and smell of such products is particularly challenging. OBJECTIVE:The design and feasibility of a liquid placebo for STW5, an herbal medicinal produ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2012.04.003
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVES:The aim of this preliminary clinical study was to assess if the daily intake of Agaricus blazei Murill (ABM) granulated powder (SSI Co., Ltd., Tokyo, Japan) for 6 months improved the quality of life (QOL) in cancer patients in remission. DESIGN:Open study. SETTING:Subjects diurnally took 1 (1.8 g; N=23), 2...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2013.07.001
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Colonic diverticula develop in at least 60% of elderly patients. Less than 25% of these develop diverticulitis. Recurrent episodes are experienced by about 13% of the symptomatic patients. The effect on prevention of recurrent diverticulitis of currently used therapies is controversial. Surgical colon resect...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2018.03.013
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Over one-third of cardiac patients practice Mind-Body Therapy (MBT), particularly women. Considering women are less likely to engage in conventional physical activity, few studies have examined why MBT is well-accepted by women. OBJECTIVES:To qualitatively explore gender differences in the motivations for, ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2008.04.009
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:This was a secondary data analysis of a cluster-randomized clinical trial that tested the efficacy of a 20-week Sun-style Tai Chi (TC) program in reducing pain in community-dwelling elders with cognitive impairment and knee osteoarthritis (OA). The study also examined whether elders' level of cognitive functi...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2015.06.001
更新日期：2015-08-01 00:00:00
abstract：:Writers on homoeopathy frequently refer to classical homoeopathy, usually with the implication that this is the most complete and authoritative version of Hahnemann's views. However, such claims do not correspond with the historical facts. Homoeopathy arrived in the USA early in the 19th century and there underwent co...
journal_title：Complementary therapies in medicine
pub_type： 历史文章,杂志文章,评审
doi：10.1016/s0965-2299(99)80085-5
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of ethnicity as a predictor of the use of complementary and alternative medicine (CAM) among patients with diabetes. DESIGN AND SETTINGS:A 16-item questionnaire investigating CAM use was distributed among patients attending the Taking Control of Your Diabetes (TCOYD) educational confer...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2010.09.007
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Despite several studies about the effects of saffron supplementation on serum concentrations of lipid and glucose profiles, no systematic study had summarized the findings. Therefore, we conduct current study to systematically summarize findings from studies about the effect of saffron supplementation on ser...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.07.017
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:Traditional Chinese medicine are commonly used for treatment of asthma. However, there are only very limited data about its efficacy in children. Therefore, we aimed to determine the efficacy of augmented Yu Ping Feng San (aYPFS) as an add-on to oral montelukast compared with montelukast alone for treatment ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2016.10.010
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND & OBJECTIVE(S):Obesity is a worldwide epidemic and a common medical condition associated with a variety of chronic diseases. Cereal beta-glucans are soluble fibers with potential health benefits. A number of randomized controlled trials (RCTs) have investigated the effect of cereal beta-glucan consumption on...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.01.018
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Mindful walking (MW) interventions employ mindfulness training combined with physical activity. Wearable mobile devices have been increasingly used to measure outcomes of physical activity interventions. The purpose of this study was to understand MW participants' attitudes towards MW and the use of mobile d...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2020.102640
更新日期：2020-12-31 00:00:00
abstract：:The aim of this study was to evaluate the acute effects of light-emitting diode therapy (LEDT) on cardiopulmonary adjustments and muscle oxygenation dynamics during transition to moderate exercise, as well as in glucose and lactate levels in patients with type 2 diabetes mellitus (T2DM). Sixteen individuals with T2DM ...
journal_title：Complementary therapies in medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ctim.2018.11.015
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:We report a case of congestive heart failure complicated by hospital-acquired pneumonia that was successfully treated with traditional Chinese medicine (TCM) and antibiotics. CLINICAL FEATURES AND OUTCOME:A 33-year-old man with a history of heart failure developed pneumonia during hospitalization. After the ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.01.008
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:Recent studies have found that garlic supplementation can improve antioxidant status, however, there is no definitive consensus on this context. The present systematic review and meta-analysis aimed to investigate the effect of garlic supplementation on oxidative stress markers. SETTING:We searched titles, a...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2020.102385
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:The goal of this study was to synthesize evidence regarding the efficacy of inhalation aromatherapy in patients undergoing cardiac surgery. METHODS:We conducted an electronic search of four authentic databases. Randomized controlled trials (RCTs), which compared inhalation aromatherapy versus control in pati...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.102256
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The objective of meta-analysis of randomized controlled trials (RCTs) was to evaluate the effects of probiotic supplementation on metabolic status in patients with neurological disorders. METHODS:The following databases were search up to April 2019: Pubmed, Scopus, Google scholar, Web of Scien...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ctim.2020.102507
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:While several cross-sectional studies have examined psychological correlates of complementary and alternative medicine (CAM) use and cancer, few prospective longitudinal investigations have been reported. This study examined whether CAM use moderated distress and quality of life (HRQoL) from pre- to post-can...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2011.09.008
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of ballroom and Latin American dancing classes on turning in people with Parkinson's. DESIGN:This study employed a randomised, controlled, experimental design. SETTING:Dance classes were performed in a community dance centre in Southern England and all assessments took place a gai...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2017.03.012
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:The primary aim was to describe the characteristics of acupuncture patients and in particular the main problem or symptom for which they were seeking treatment. Our secondary aim was to compare the profiles of acupuncture patients with those of a patient survey undertaken in 1988. METHODS:We used the data fr...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2005.07.006
更新日期：2006-03-01 00:00:00
