Assessment of the feasibility of a rehabilitation intervention program for breast cancer survivors with cognitive complaints.


:To assess the feasibility of a cognitive rehabilitation program in breast cancer survivors (BCS) with persistent post-treatment cognitive complaints. BCS with cognitive complaints, 18-months to 5-years post-treatment, were recruited for a once-weekly, five-week, group cognitive training intervention. Outcome measures included self-reported mood and cognitive function, and neurocognitive tests administered at pre-intervention, immediate-, two-month and four-month post-intervention. A sub-study in eight participants evaluated resting state quantitative electroencephalography (qEEG) changes from pre- to immediate post-intervention in relationship to post-intervention changes in cognitive complaints. Twenty-seven BCS completed the protocol and tolerated the intervention well. We observed significant reductions in total and memory-specific cognitive complaints from pre-intervention to immediate post-intervention (p = 0.031 and p = 0.009, respectively) and at four-months post-intervention (p < 0.0001 and p < 0.001, respectively). Significant improvement in neurocognitive tests were found for Symbol Digit, Stroop, and Trails A tests (df = 26, all p's <0.05). Effect sizes for changes from pre-intervention to immediate and to four-month post intervention ranged from 0.429 to 0.607, and from 0.439 to 0.741, respectively. Increase in qEEG absolute alpha power over the course of the intervention was associated with reduced complaints at immediate post-intervention (r = -0.78, p = 0.021), two-months (r range = -0.76 to -0.82, p-value range 0.004 to 0.03), and four-months (r = -0.71, p = 0.048). A five-week group cognitive training intervention is feasible and well tolerated. Cognitive complaints and neurocognitive test performances showed positive changes. qEEG may serve as a potential biomarker for improvement in self-reported complaints. A randomized clinical trial is underway to test the efficacy of the intervention.


Brain Imaging Behav


Ercoli LM,Castellon SA,Hunter AM,Kwan L,Kahn-Mills BA,Cernin PA,Leuchter AF,Ganz PA




Has Abstract


2013-12-01 00:00:00












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    abstract::Dementia with Lewy bodies (DLB) is often associated with occipital hypometabolism or hypoperfusion, as well as deficits in cholinergic neurotransmission. In this study, 11 mild DLB, 16 mild AD and 16 age-matched controls underwent arterial spin-labeled perfusion MRI (ASL-pMRI) and neuropsychological testing. Patterns ...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Fong TG,Inouye SK,Dai W,Press DZ,Alsop DC

    更新日期:2011-03-01 00:00:00

  • Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Müller-Oehring EM,Sullivan EV,Pfefferbaum A,Huang NC,Poston KL,Bronte-Stewart HM,Schulte T

    更新日期:2015-09-01 00:00:00

  • Altered white matter structural networks in drug-naïve patients with obsessive-compulsive disorder.

    abstract::White matter (WM) alteration is considered to be a vital neurological mechanism of obsessive-compulsive disorder (OCD). However, little is known regarding the changes in topological organization of WM structural network in OCD. We acquired diffusion tensor imaging (DTI) datasets from 28 drug-naïve OCD patients and 28 ...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Zhou C,Ping L,Chen W,He M,Xu J,Shen Z,Lu Y,Shang B,Xu X,Cheng Y

    更新日期:2020-04-20 00:00:00

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Rodriguez-Porcel F,Wilmskoetter J,Cooper C,Taylor JA,Fridriksson J,Hickok G,Bonilha L

    更新日期:2020-10-12 00:00:00

  • Localizing deficits in white matter tracts of patients with narcolepsy with cataplexy: tract-specific statistical analysis.

    abstract::White matter alterations related to hypocretin pathway have been less evaluated in patients who have narcolepsy with cataplexy (NC), as compared to the identified exploration of gray matter and have varied among structural brain magnetic resonance imaging studies. The aim of this study was to investigate the disruptio...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Park HR,Kim HR,Seong JK,Joo EY

    更新日期:2020-10-01 00:00:00

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Brugulat-Serrat A,Salvadó G,Sudre CH,Grau-Rivera O,Suárez-Calvet M,Falcon C,Sánchez-Benavides G,Gramunt N,Fauria K,Cardoso MJ,Barkhof F,Molinuevo JL,Gispert JD,ALFA Study.

    更新日期:2020-10-01 00:00:00

  • Atypical PT anatomy in children with autism spectrum disorder with expressive language deficits.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Knaus TA,Kamps J,Foundas AL,Tager-Flusberg H

    更新日期:2018-10-01 00:00:00

  • Altered gray matter volume in primary insomnia patients: a DARTEL-VBM study.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Li M,Yan J,Li S,Wang T,Wen H,Yin Y,Fu S,Zeng L,Tian J,Jiang G

    更新日期:2018-12-01 00:00:00

  • Alcoholism and sexual dimorphism in the middle longitudinal fascicle: a pilot study.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Seitz J,Sawyer KS,Papadimitriou G,Oscar-Berman M,Ng I,Kubicki A,Mouradian P,Ruiz SM,Kubicki M,Harris GJ,Makris N

    更新日期:2017-08-01 00:00:00

  • Metabolic imaging of mild traumatic brain injury.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章,评审


    authors: Lin AP,Liao HJ,Merugumala SK,Prabhu SP,Meehan WP 3rd,Ross BD

    更新日期:2012-06-01 00:00:00

  • Only-child and non-only-child exhibit differences in creativity and agreeableness: evidence from behavioral and anatomical structural studies.

    abstract::Different family composition and size inevitably make only-children different from non-only-children. Previous studies have focused on the differences in behaviors, such as cognitive function and personality traits, between the only-child and the non-only-child. However, there are few studies that have focused on the ...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Yang J,Hou X,Wei D,Wang K,Li Y,Qiu J

    更新日期:2017-04-01 00:00:00

  • Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Irimia A,Torgerson CM,Goh SY,Van Horn JD

    更新日期:2015-12-01 00:00:00

  • Brain structural connectomes indicate shared neural circuitry involved in subjective experience of cognitive and physical fatigue in older adults.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Baran TM,Zhang Z,Anderson AJ,McDermott K,Lin F

    更新日期:2020-12-01 00:00:00

  • Functional connectivity of posterior cingulate gyrus in heroin dependents treated by methadone maintenance and protracted abstinence measures: an event-related fMRI study.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Wei X,Chen J,Zhu J,Li Q,Li W,Wang W

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    pub_type: 杂志文章,meta分析,评审


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    更新日期:2016-09-01 00:00:00

  • Trait and state patterns of basolateral amygdala connectivity at rest are related to endogenous testosterone and aggression in healthy young women.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Buades-Rotger M,Engelke C,Krämer UM

    更新日期:2019-04-01 00:00:00

  • The reliability of individual differences in face-selective responses in the fusiform gyrus and their relation to face recognition ability.

    abstract::Face recognition ability varies widely in the normal population and there is increasing interest in linking individual differences in perception to their neural correlates. Such brain-behavior correlations require that both the behavioral measures and the selective BOLD responses be reliable. The reliability of the lo...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: McGugin RW,Gauthier I

    更新日期:2016-09-01 00:00:00

  • Schizophrenia-related abnormalities in the triple network: a meta-analysis of working memory studies.

    abstract::Previous meta-analyses found abnormal brain activations in schizophrenia patients compared with normal controls when performing working memory tasks. Although most studies focused on dysfunction of the working memory activation network in schizophrenia patients, deactivation abnormalities of the working memory in the ...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Wu D,Jiang T

    更新日期:2020-08-01 00:00:00

  • Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma.

    abstract::Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease thought to be caused, at least in part, by repetitive brain trauma, including concussive and subconcussive injuries. It is thought to result in executive dysfunction, memory impairment, depression and suicidality, apathy, poor impulse control, and e...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章,评审


    authors: Baugh CM,Stamm JM,Riley DO,Gavett BE,Shenton ME,Lin A,Nowinski CJ,Cantu RC,McKee AC,Stern RA

    更新日期:2012-06-01 00:00:00

  • Increased brain connectivity and activation after cognitive rehabilitation in Parkinson's disease: a randomized controlled trial.

    abstract::Cognitive rehabilitation programs have demonstrated efficacy in improving cognitive functions in Parkinson's disease (PD), but little is known about cerebral changes associated with an integrative cognitive rehabilitation in PD. To assess structural and functional cerebral changes in PD patients, after attending a thr...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章,随机对照试验


    authors: Díez-Cirarda M,Ojeda N,Peña J,Cabrera-Zubizarreta A,Lucas-Jiménez O,Gómez-Esteban JC,Gómez-Beldarrain MÁ,Ibarretxe-Bilbao N

    更新日期:2017-12-01 00:00:00

  • Functional reorganization during cognitive function tasks in patients with amyotrophic lateral sclerosis.

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    pub_type: 杂志文章


    authors: Keller J,Böhm S,Aho-Özhan HEA,Loose M,Gorges M,Kassubek J,Uttner I,Abrahams S,Ludolph AC,Lulé D

    更新日期:2018-06-01 00:00:00

  • Gray & white matter tissue contrast differentiates Mild Cognitive Impairment converters from non-converters.

    abstract::The clinical relevance of gray/white matter contrast ratio (GWR) in mild cognitive impairment (MCI) remains unknown. This study examined baseline GWR and 3-year follow-up diagnostic status in MCI. Alzheimer's Disease Neuroimaging Initiative MCI participants with baseline 1.5 T MRI and 3-year follow-up clinical data we...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Jefferson AL,Gifford KA,Damon S,Chapman GW 4th,Liu D,Sparling J,Dobromyslin V,Salat D,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期:2015-06-01 00:00:00

  • Altered regional brain volumes in elderly carriers of a risk variant for drug abuse in the dopamine D2 receptor gene (DRD2).

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Roussotte FF,Jahanshad N,Hibar DP,Thompson PM,Alzheimer’s Disease Neuroimaging Initiative (ADNI).

    更新日期:2015-06-01 00:00:00

  • Neural correlates of personality dimensions and affective measures during the anticipation of emotional stimuli.

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    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Brühl AB,Viebke MC,Baumgartner T,Kaffenberger T,Herwig U

    更新日期:2011-06-01 00:00:00

  • Spatial distribution bias in subject-specific abnormalities analyses.

    abstract::The neuroimaging community has seen a renewed interest in algorithms that provide a location-independent summary of subject-specific abnormalities (SSA) to assess individual lesion load. More recently, these methods have been extended to assess whether multiple individuals within the same cohort exhibit extrema in the...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Dodd AB,Ling JM,Bedrick EJ,Meier TB,Mayer AR

    更新日期:2018-12-01 00:00:00

  • Relationship of negative urgency to cingulo-insular and cortico-striatal resting state functional connectivity in tobacco use.

    abstract::Negative urgency, defined as a tendency to act rashly under extreme negative emotion, is strongly associated with tobacco use. Despite the robust evidence linking negative urgency and tobacco use and accumulating evidence suggesting that localized, segregated brain regions such as the nucleus accumbens (NAcc), insula,...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Um M,Hummer TA,Cyders MA

    更新日期:2020-10-01 00:00:00

  • Effects of temporarily disrupting BBB on activity-induced manganese-dependent functional MRI.

    abstract::This study further investigates the influence of temporarily disrupting the blood-brain barrier (BBB) on the level of manganese used in AIM fMRI other than the recognized function of allowing that substance to enter into the activated brain regions more effectively during the BBB opening. We injected manganese into Wi...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Fa Z,Zhang R,Li P,Zhang J,Zhang P,Zhu S,Wu Q,Huang F,Liu Y,Yang L,Chang H,Wen Z,Gao D,Zeng Y,Jiang X

    更新日期:2011-09-01 00:00:00

  • Abnormal white matter tracts of insula in smokers.

    abstract::Nicotine addiction is characterized as a neural circuit dysfunction, particularly with regard to the alterations in central reward pathways. The insula, a cortical region that is thought to play a central role in this reward circuitry, has been implicated in the maintenance of nicotine addiction. However, it remains l...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Wang C,Wang S,Huang P,Shen Z,Qian W,Luo X,Li K,Zeng Q,Gu Q,Yu H,Yang Y,Zhang M

    更新日期:2020-09-24 00:00:00

  • Changes in dynamic resting state network connectivity following aphasia therapy.

    abstract::Resting state magnetic resonance imaging (rsfMRI) permits observation of intrinsic neural networks produced by task-independent correlations in low frequency brain activity. Various resting state networks have been described, with each thought to reflect common engagement in some shared function. There has been limite...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Duncan ES,Small SL

    更新日期:2018-08-01 00:00:00

  • Recognition of faces and names: multimodal physiological correlates of memory and executive function.

    abstract::We sought to characterize electrophysiological, eye-tracking and behavioral correlates of face-name recognition memory in healthy younger adults using high-density electroencephalography (EEG), infrared eye-tracking (ET), and neuropsychological measures. Twenty-one participants first studied 40 face-name (FN) pairs; 2...

    journal_title:Brain imaging and behavior

    pub_type: 杂志文章


    authors: Mitchell MB,Shirk SD,McLaren DG,Dodd JS,Ezzati A,Ally BA,Atri A

    更新日期:2016-06-01 00:00:00