The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.

abstract：:The highly populated coasts of the Bay of Bengal are particularly vulnerable to water-borne diseases, pollution and climatic extremes. The environmental factors behind bacterial community composition and Vibrio distribution were investigated in an estuarine system of a cholera-endemic region in the coastline of Bangla...

journal_title：Frontiers in microbiology

authors： Kopprio GA,Neogi SB,Rashid H,Alonso C,Yamasaki S,Koch BP,Gärdes A,Lara RJ

更新日期：2020-04-15 00:00:00

abstract：:Africa, Asia, and Latin America are regions highly affected by endemic diseases, such as Leishmaniasis, Malaria, and Chagas' disease. They are responsible for the death of 1000s of patients every year, as there is not yet a cure for them and the drugs used are inefficient against the pathogenic parasites. During the l...

journal_title：Frontiers in microbiology

authors： Lacerda AF,Pelegrini PB,de Oliveira DM,Vasconcelos ÉA,Grossi-de-Sá MF

更新日期：2016-02-05 00:00:00

abstract：:Listeria monocytogenes (Lm) is a foodborne zoonotic pathogen that causes listeriosis with a mortality rate of 20-30%. Serovar 4b and 1/2b isolates account for most of listeriosis outbreaks, however, no listeriosis vaccine is available for either prophylactic or therapeutic use. Here, we developed a triple-virulence-ge...

journal_title：Frontiers in microbiology

authors： Meng F,Zhu T,Yao H,Ling Z,Feng Y,Li G,Li J,Sun X,Chen J,Meng C,Jiao X,Yin Y

更新日期：2020-12-11 00:00:00

abstract：:Legionella pneumophila is a natural intracellular bacterial parasite of free-living freshwater protozoa and an accidental human pathogen that causes Legionnaires' disease. L. pneumophila differentiates, and does it in style. Recent experimental data on L. pneumophila's differentiation point at the existence of a compl...

journal_title：Frontiers in microbiology

authors： Robertson P,Abdelhady H,Garduño RA

更新日期：2014-12-22 00:00:00

abstract：:Monacolin K (MK) is a secondary metabolite of the Monascus species that can inhibit cholesterol synthesis. Functional red mold rice (FRMR) is the fermentation product of Monascus spp., which is rich in MK. FRMR is usually employed to regulate serum cholesterol, especially for hypercholesterolemic patients who refuse s...

journal_title：Frontiers in microbiology

authors： Yanli F,Xiang Y

更新日期：2020-11-25 00:00:00

abstract：:The threat of bioterrorism and pandemics has highlighted the urgency for rapid and reliable bioaerosol detection in different environments. Safeguarding against such threats requires continuous sampling of the ambient air for pathogen detection. In this study we investigated the efficacy of the Airborne Sample Analysi...

journal_title：Frontiers in microbiology

authors： Sharma A,Clark E,McGlothlin JD,Mittal SK

更新日期：2015-05-27 00:00:00

abstract：:Organic farming system and sustainable management of soil pathogens aim at reducing the use of agricultural chemicals in order to improve ecosystem health. Despite the essential role of microbial communities in agro-ecosystems, we still have limited understanding of the complex response of microbial diversity and comp...

journal_title：Frontiers in microbiology

authors： Lupatini M,Korthals GW,de Hollander M,Janssens TK,Kuramae EE

更新日期：2017-01-04 00:00:00

abstract：:Chlorpyrifos (CP) is one of the most widely used organophosphate pesticides in agriculture worldwide, but its extensive use has led to the contamination of various soil and water systems. Microbial bioremediation is considered to be one of the most viable options for the removal of CP from the environment; however, li...

journal_title：Frontiers in microbiology

authors： Rayu S,Nielsen UN,Nazaries L,Singh BK

更新日期：2017-04-04 00:00:00

abstract：:Prostatitis has various etiology including bacterial infection and dysregulated immunity; some of its forms remain a serious therapeutic challenge. Inflammation occurs in all forms of this disorder and is proposed to predispose to the development of prostate cancer (PC). There are reports that phage therapy is effecti...

journal_title：Frontiers in microbiology

authors： Górski A,Jończyk-Matysiak E,Łusiak-Szelachowska M,Międzybrodzki R,Weber-Dąbrowska B,Borysowski J,Letkiewicz S,Bagińska N,Sfanos KS

更新日期：2018-06-29 00:00:00

abstract：:Cefquinome is a fourth generation cephalosporin with antimicrobial activity against gram negative and gram positive bacterial species, including Staphylococcus aureus. The aim of our study was to observe the ex-vivo activity of cefquinome against Staphylococcus aureus strains by using bovine serum from intravenously t...

journal_title：Frontiers in microbiology

authors： Ahmad I,Hao H,Huang L,Sanders P,Wang X,Chen D,Tao Y,Xie S,Xiuhua K,Li J,Dan W,Yuan Z

更新日期：2015-06-17 00:00:00

abstract：:Listeria monocytogenes (Lm) is a common environmental bacterium that thrives on vegetation and soil matter, but can infect humans if contaminated food products are ingested, resulting in severe disease in immunosuppressed populations, including pregnant women and newborns. To better understand how the unique immunolog...

journal_title：Frontiers in microbiology

authors： Wolfe B,Kerr AR,Mejia A,Simmons HA,Czuprynski CJ,Golos TG

更新日期：2019-09-11 00:00:00

abstract：:Orf virus (ORFV), a member of Parapoxvirus, has evolved various strategies to modulate the immune responses of host cells. The ORFV-encoded protein ORFV002, a regulator factor, has been found to inhibit the acetylation of NF-κB-p65 by blocking phosphorylation of NF-κB-p65 at Ser(276) and also to disrupt the binding of...

journal_title：Frontiers in microbiology

authors： Chen D,Zheng Z,Xiao B,Li W,Long M,Chen H,Li M,Rock DL,Hao W,Luo S

更新日期：2016-09-13 00:00:00

abstract：:Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in intracellular Ca2+ secretion within CHPV infected cells that fur...

journal_title：Frontiers in microbiology

authors： Verma AK,Ghosh S,Basu A

更新日期：2018-07-06 00:00:00

abstract：:Klebsiella pneumoniae is an important nosocomial pathogen with an extraordinary resistant phenotype due to a combination of acquired resistant-elements and efflux mechanisms. In this study a detailed molecular characterization of 11 K. pneumoniae isolates of clinical origin was carried out. Eleven clinical isolates we...

journal_title：Frontiers in microbiology

authors： Anes J,Hurley D,Martins M,Fanning S

更新日期：2017-10-23 00:00:00

abstract：:Clostridium difficile PCR ribotype (RT) 014 is well-established in both human and porcine populations in Australia, raising the possibility that C. difficile infection (CDI) may have a zoonotic or foodborne etiology. Here, whole genome sequencing and high-resolution core genome phylogenetics were performed on a contem...

journal_title：Frontiers in microbiology

authors： Knight DR,Squire MM,Collins DA,Riley TV

更新日期：2017-01-11 00:00:00

abstract：:Many Gram-negative bacteria use a type VI secretion system (T6SS) for microbial warfare and/or host manipulation. Acinetobacter baumannii is an important nosocomial pathogen and many A. baumannii strains utilize a T6SS to deliver toxic effector proteins to surrounding bacterial cells. These toxic effectors are usually...

journal_title：Frontiers in microbiology

authors： Lewis JM,Deveson Lucas D,Harper M,Boyce JD

更新日期：2019-10-30 00:00:00

abstract：:Upon intracellular cues, bacterial mRNA leaders often form secondary structures that determine expression of a downstream protein-coding region(s), thereby providing bacteria with a mechanism to control the amounts of necessary proteins in the right locales. Here we describe a polycistronic mRNA leader that secures ba...

journal_title：Frontiers in microbiology

authors： Park M,Kim H,Nam D,Kweon DH,Shin D

更新日期：2019-12-06 00:00:00

abstract：:Objectives: Increasing resistance of microorganisms and particularly tolerance of bacterial biofilms against antibiotics require the need for alternative antimicrobial substances. S. aureus is the most frequent pathogen causing vascular graft infections. In order to evaluate the antimicrobial efficacy, quantification ...

journal_title：Frontiers in microbiology

authors： Herten M,Bisdas T,Knaack D,Becker K,Osada N,Torsello GB,Idelevich EA

更新日期：2017-12-05 00:00:00

abstract：:Lactobacillus (L. casei) Zhang is a koumiss-originated probiotic strain, which was used as a model in a long-term antibiotics-driven evolution experiment to reveal bacterial evolutionary dynamics; and we isolated gentamycin-resistant L. casei Zhang descendents. To decipher the gentamycin resistance mechanism, here we ...

journal_title：Frontiers in microbiology

authors： Zhang W,Guo H,Cao C,Li L,Kwok LY,Zhang H,Sun Z

更新日期：2017-11-23 00:00:00

abstract：:Influenza virus RNA-dependent RNA polymerase (RdRp) is a heterotrimer of three viral proteins, PB1, PB2, and PA and is involved in both transcription and replication of the negative strand of the viral RNA (vRNA) genome. RdRp is multifunctional, possessing RNA polymerase, cap binding, and endonuclease activities. The ...

journal_title：Frontiers in microbiology

authors： Miyake Y,Ishii K,Honda A

更新日期：2017-02-09 00:00:00

abstract：:Biological wastewater treatment plants (BWWTPs) based on the activated sludge (AS) process have dramatically improved worldwide water sanitation despite increased urbanization and industrialization. However, current AS-based operations are considered economically and environmentally unsustainable. In this Perspective,...

journal_title：Frontiers in microbiology

authors： Sheik AR,Muller EE,Wilmes P

更新日期：2014-03-03 00:00:00

abstract：:Ecological significance of trees growing in urban and peri-urban settings is likely to increase in future land-use regimes, calling for better understanding of their role as potential reservoirs or stepping stones for associated biodiversity. We studied the diversity of fungal endophytes in woody tissues of asymptomat...

journal_title：Frontiers in microbiology

authors： Agostinelli M,Cleary M,Martín JA,Albrectsen BR,Witzell J

更新日期：2018-08-03 00:00:00

abstract：:In this study, we integrated geochemical measurements, microbial diversity surveys and physiological characterization of laboratory strains to investigate substrate-attached filamentous microbial biofilms at Tor Caldara, a shallow-water gas vent in the Tyrrhenian Sea. At this site, the venting gases are mainly compose...

journal_title：Frontiers in microbiology

authors： Patwardhan S,Foustoukos DI,Giovannelli D,Yücel M,Vetriani C

更新日期：2018-12-06 00:00:00

abstract：:RNA silencing mediated by microRNAs (miRNAs) is a recently discovered gene regulatory mechanism involved in various aspects of biology, such as development, cell differentiation and proliferation, and innate immunity against viral infections. miRNAs, which are a class of small (21-25 nucleotides) RNAs, target messenge...

journal_title：Frontiers in microbiology

authors： Tsunetsugu-Yokota Y,Yamamoto T

更新日期：2010-10-13 00:00:00

abstract：:Salmonella enterica subsp. enterica serovar Typhimurium is a common cause of enterocolitis in humans globally, with multidrug resistant (MDR) strains posing an enhanced threat. S. Typhimurium is also a pathogen in food-production animals, and these populations can act as reservoirs of the bacterium. Therefore, surveil...

journal_title：Frontiers in microbiology

authors： Mellor KC,Petrovska L,Thomson NR,Harris K,Reid SWJ,Mather AE

更新日期：2019-04-12 00:00:00

abstract：:Type VI CRISPR-Cas systems contain a single effector nuclease (Cas13) that exclusively targets single-stranded RNA. It remains unknown how these systems acquire spacers. It has been suggested that type VI systems with adaptation modules can acquire spacers from RNA bacteriophages, but sequence similarities suggest tha...

journal_title：Frontiers in microbiology

authors： Toro N,Mestre MR,Martínez-Abarca F,González-Delgado A

更新日期：2019-09-13 00:00:00

abstract：:The ability of human enteric pathogens to colonize plants and use them as alternate hosts is now well established. Salmonella, similarly to phytobacteria, appears to be capable of producing the plant hormone auxin via an indole-3-pyruvate decarboxylase (IpdC), a key enzyme of the IPyA pathway. A deletion of the Salmon...

journal_title：Frontiers in microbiology

authors： Cox CE,Brandl MT,de Moraes MH,Gunasekera S,Teplitski M

更新日期：2018-01-12 00:00:00

abstract：:Globally, mosquitoes are known to be competent vectors to various arboviruses that cause serious and debilitating diseases to humans and animals. Conversely, mosquitoes harbor a wide array of insect specific viruses (ISVs) that are generally neglected. Extensive characterization of these ISVs is important in understan...

journal_title：Frontiers in microbiology

authors： Zhao L,Mwaliko C,Atoni E,Wang Y,Zhang Y,Zhan J,Hu X,Xia H,Yuan Z

更新日期：2019-08-22 00:00:00

abstract：:Gut microbiota play a key role in the development of metabolic disorders. Defining and correlating structural shifts in gut microbial assemblages with conditions related to metabolic syndrome have, however, been proven difficult. Results from 16S genomic DNA and 16S ribosomal RNA analyses of fecal samples may differ w...

journal_title：Frontiers in microbiology

authors： Ji Y,Park S,Park H,Hwang E,Shin H,Pot B,Holzapfel WH

更新日期：2018-04-10 00:00:00

abstract：:Biofilms are assemblages of microorganisms attached to each other, or to a surface, and encased in a protective, self-produced matrix. Such associations are now recognized as the predominant microbial growth mode. The physiology of cells in biofilms differs from that of the planktonic cells on which most research has ...

journal_title：Frontiers in microbiology

authors： Penesyan A,Paulsen IT,Gillings MR,Kjelleberg S,Manefield MJ

更新日期：2020-09-02 00:00:00