Physiological role of adiponectin in different tissues: a review.

Abstract:

:Adiponectin is the most important adipokine secreted by the adipose tissue. It carries out an important role in setting up the metabolism and improving the function of various organs. Adiponectin in the kidneys prevents degradation of the renal arteries, reduces protein excretion, and improves filtration. This role is accomplished by regulating anabolic pathways and reducing oxidative stress in the renal tissue. This hormone in the liver prevents the accumulation of fat and free radicals that cause damage to liver cells and tissue. This adipokine, by preventing inflammatory processes, oxidative stress, obesity and insulin resistance, improves vascular function and prevents the development of atherosclerosis. It seems that adiponectin can also be a therapeutic target for many metabolic diseases. This study aims to clarify the adipose tissue discharge. Here, the diverse physiological actions of adiponectin were reviewed to provide an overview of its therapeutic potential in different metabolic disorders.

journal_name

Arch Physiol Biochem

authors

Esmaili S,Hemmati M,Karamian M

doi

10.1080/13813455.2018.1493606

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

67-73

issue

1

eissn

1381-3455

issn

1744-4160

journal_volume

126

pub_type

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