Abstract：
:Histamine is a biogenic amine that plays an essential role in controlling many physiological functions, both in the central nervous system (CNS) and the peripheral nervous system (PNS). Most of these physiological effects are mediated through interactions with four histamine receptor subtypes, all of which are members of the larger family of rhodopsin-like class A G-protein coupled receptors (GPCRs) (Leurs et al., 2011; Lim et al., 2009). Here, we focus on the genetic variations and polymorphisms localized on the genes encoding for human histamine receptors where it provides an up to date collection of all polymorphisms found on genes encoding the histamine receptor subtypes and their association to diseases.
journal_name
Life Scijournal_title
Life sciencesauthors
Micallef S,Stark H,Sasse Adoi
10.1016/j.lfs.2013.08.012subject
Has Abstractpub_date
2013-10-10 00:00:00pages
487-94issue
15eissn
0024-3205issn
1879-0631pii
S0024-3205(13)00478-5journal_volume
93pub_type
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