Abstract：
:Mycobacterium ulcerans infection results in significant disfiguring morbidity, and treatment is expensive. To estimate the cost of treatment in the antibiotic era, a retrospective study of 71 patients diagnosed and treated for M. ulcerans in the Bellarine Peninsula (Victoria, Australia) between 1998 and 2006 was performed. Patients were categorised into minor single episode infection, major single episode infection and recurrent disease. Data were collected on each treatment cost component. To determine the change from costs in the pre-antibiotic era, mean direct costs were compared with those from a study in a nearby region between 1991 and 1998. All costs were in Australian dollars in 2006-2007 prices. The mean overall cost was $6181 per episode, with the highest cost components being hospitalisation (mean $3977; 63%) and surgeon fees ($949; 12%). Treatment costs per episode increased significantly from minor infection ($2235) to major infection ($6338) to recurrent disease ($13 372). Compared with the pre-antibiotic era, costs have significantly decreased, with a 52% reduction in overall cost per episode, driven mainly by a reduction in hospitalisation costs. Therefore, earlier diagnosis and treatment of M. ulcerans, including the use of outpatient-based oral antibiotic regimens, has the potential to reduce the cost of treatment.
journal_name
Int Healthjournal_title
International healthauthors
Pak J,O'Brien DP,Quek T,Athan Edoi
10.1016/j.inhe.2011.12.005subject
Has Abstractpub_date
2012-06-01 00:00:00pages
123-7issue
2eissn
1876-3413issn
1876-3405pii
j.inhe.2011.12.005journal_volume
4pub_type
杂志文章abstract：:The Global Trachoma Mapping Project (GTMP) is the largest infectious disease survey ever undertaken. With 60 partners, 2.6 million people were examined across 29 countries for the blinding neglected tropical disease (NTD) trachoma, establishing the prevalence of the disease globally. Such an achievement was only made ...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihy054
更新日期：2019-01-01 00:00:00
abstract：Background:The State of Meghalaya, India, has some of the worst newborn health outcomes in the country. State health authorities commissioned an assessment of newborn service delivery to improve services. This study proposes bottleneck analysis (BNA) and quality improvement (QI) methods as a combined method to improve ...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihy062
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:A secondary analysis was conducted of two separate datasets to observe the association between maternal age and interpregnancy interval (IPI). METHODS:The IPI in a middle-income country (Guatemala) was compared with that of a very-high-income country (USA) among women with two pregnancies. RESULTS:A regres...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihaa085
更新日期：2020-11-04 00:00:00
abstract：BACKGROUND:Anaemia is a global public health problem affecting both developing and developed countries with major consequences for human health and socioeconomic development. This paper examines the possible relationship between Hb concentration and severity of anaemia with individual and household characteristics of c...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/iht034
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Community health workers (CHWs) are an essential cadre in the health systems of many low- and middle-income countries. These workers provide a wide variety of services and are key to ongoing processes of task shifting within human immunodeficiency virus programmes in particular. Ward-based outreach teams (WB...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz082
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Access to prompt and effective treatment of malaria is a fundamental right of all populations at risk; many countries have not met the target of 60% of children treated with effective antimalarial drugs within 24 h of fever onset. While community case management of malaria is effective for increasing coverag...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/iht017
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:A modelling analysis carried out in 2014 suggested that, without cervical cancer screening programmes, the incidence of cervical cancer in Denmark, Finland, Norway and Sweden would have been as high as that in some low- and middle-income countries. We compare programme strategies between Nigeria and these No...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihaa062
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND:Strategies are urgently needed to mitigate the risk of zoonotic disease emergence in southern China, where pathogens with zoonotic potential are known to circulate in wild animal populations. However, the risk factors leading to emergence are poorly understood, which presents a challenge in developing approp...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihaa001
更新日期：2020-02-12 00:00:00
abstract：BACKGROUND:Individuals in rural communities in Madagascar must frequently travel long distances, over difficult terrain, to obtain basic care. The quality of care is often inconsistent and inadequate. METHODS:An exploratory mixed-methods study was conducted in select coastal communities in the Maroantsetra region of M...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihy070
更新日期：2019-05-01 00:00:00
abstract：:Humanitarian agencies regularly carry out nutrition surveys to estimate the prevalence of acute malnutrition (wasting) and mortality as well as to collect data on a wide range of contributory or aggravating factors in order to identify interventions and to direct aid where it is most needed. In this study, the case of...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2011.01.003
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:Malaysia is an upper-middle income country with a tax-based health financing system. Health care is relatively affordable, and safety nets are provided for the needy. The objectives of this study were to determine the out-of-pocket health spending, proportion of catastrophic health spending (out-of-pocket sp...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihw054
更新日期：2017-01-01 00:00:00
abstract：:Community sensitisation, as a component of community engagement, plays an important role in strengthening the ethics of community-based trials in developing countries and is fundamental to trial success. However, few researchers have shared their community sensitisation strategies and experiences. We report on our per...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2011.10.003
更新日期：2012-03-01 00:00:00
abstract：:The Lymphatic Filariasis (LF) Non-governmental Development Organization (NGDO) Network was established to engage in supporting both international and national LF elimination agendas covering areas such as assisting ministries of health as an on-the-ground link between communities and programmes, which additionally giv...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihaa049
更新日期：2020-12-22 00:00:00
abstract：BACKGROUND:There are conflicting reports of sex differences in HIV treatment outcomes in Africa. We investigated sex disparities in treatment outcomes for adults on first line antiretroviral treatment (ART) in Nigeria. METHODS:We compared clinical and immunologic responses to ART between HIV-infected men (n=205) and w...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihw050
更新日期：2017-01-01 00:00:00
abstract：:One crucial element of the timely detection and identification of the causative agent(s) of a health emergency is access to live and historical data about the health risks in the area of concern. Therefore, sharing data on health emergencies is essential to the early investigation and detection teams. Although, theore...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz122
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:We analyzed the role that the launch of new drugs has played in reducing the number of years of life lost (YLL) before three different ages (85, 70 and 55 y) due to 66 diseases in 27 countries. METHODS:We estimated two-way fixed-effects models of the rate of decline of the disease- and country-specific age-...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz003
更新日期：2019-09-02 00:00:00
abstract：:Mental health services reforms in Latin America and the Caribbean in the last 20 years have led to a significant improvement of mental health services. They also contributed to the development of new evidence that may help the implementation of future reforms. These advances, however, were clearly insufficient to resp...
journal_title：International health
pub_type： 杂志文章,评审
doi：10.1093/inthealth/ihs013
更新日期：2013-03-01 00:00:00
abstract：Background:Although screen time (ST) and insufficient physical activity (PA) are fairly common among adolescents, it is unclear whether these conditions are jointly associated with adolescents' psychosocial difficulties. This study aimed to examine interactive associations of ST and PA with psychosocial difficulties am...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihy019
更新日期：2018-07-01 00:00:00
abstract：:Policy-makers require information on the potential benefits of and economic case for pneumococcal conjugate vaccination in middle-income countries. We built decision analysis models to evaluate a three-dose infant series of the 7-, 10- or 13-valent pneumococcal conjugate vaccines in 77 middle-income countries compared...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2011.08.004
更新日期：2011-12-01 00:00:00
abstract：:Product Development Partnerships (PDPs) are playing an increasingly important role in the development of new medicines for neglected diseases of the developing world; however, there has been limited information on their funding and expenditure patterns. This paper analyses funding for the 14 PDPs working on neglected ...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2010.04.002
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:While access to healthcare has been a focus of international development, populations around the world continue to lack proper access to care. Identifying at-risk demographic groups can help advance efforts both regionally and internationally. There are only a small number of studies that previously have ass...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz008
更新日期：2019-11-13 00:00:00
abstract：:The care of severely malnourished children in sub-Saharan Africa is challenging, especially in HIV-prevalent settings. Recent improvements to facility-based individual case management, and increased community-based management focusing on early identification and high programme coverage have led to reductions in mortal...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2009.03.001
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) is a growing public health problem and an important cause of morbidity and mortality. Disparities in CKD may be related to social determinants and health inequalities in low- and middle-income countries. This study determined how social determinants of health influence trends in ...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz071
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:In recent years there have been several reports of outbreaks of dengue fever (DF) in Yemen. This study aimed to describe the prevailing knowledge, attitude and preventive practices regarding DF, and to investigate the factors associated with poor preventive practices in rural areas of Yemen. METHODS:A popul...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihv021
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:To observe prevalence, characteristics and outcomes associated with operative vaginal birth (OVB). METHODS:We compared spontaneous vaginal birth with OVB. RESULTS:Of 993 women, 759 (76.4%) experienced vaginal birth; 716 were spontaneous (94.3%), 14 (1.8%) underwent forceps-assisted birth and 29 (3.8%) had ...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihaa024
更新日期：2020-05-30 00:00:00
abstract：BACKGROUND:During 2009-2013, Xpert MTB/RIF testing was decentralized in Tanzania. Standardized treatment of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) was centralized at the Kibong'oto Infectious Diseases Hospital. Initially, Xpert MTB/RIF results were confirmed and complemented with phenotypic d...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz005
更新日期：2019-11-13 00:00:00
abstract：BACKGROUND:Governance of a country may have widespread effects on the health of its population, yet little is known about the effect of governance on child mortality in a country that is undergoing urbanization, economic development, and disease control. METHODS:We obtained indicators of six dimensions of governance (...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihu018
更新日期：2014-09-01 00:00:00
abstract：:After 30 years of treatment with Mectizan (ivermectin), cutaneous and ocular complications of Onchocerca volvulus infection are now scarce in endemic communities. Indeed, transmission has been interrupted and the O. volvulus- associated disease has disappeared in some African foci. Despite this success, onchocerciasis...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihx051
更新日期：2018-03-01 00:00:00
abstract：:Neglected tropical diseases (NTDs) are a group of diseases that disproportionately affect the poorest of the poor. While for years attention has focused on single diseases within this group, efforts during the past decade have resulted in their being grouped together to highlight that they are fundamentally diseases o...
journal_title：International health
pub_type： 杂志文章
doi：10.1093/inthealth/ihz048
更新日期：2019-09-02 00:00:00
abstract：:Trachoma is the leading cause of preventable blindness worldwide and is controlled with an integrated strategy of treatment and prevention which includes latrine provision and promotion. We aimed to evaluate the latrine uptake, construction, and usage in villages participating in latrine promotion programmes supported...
journal_title：International health
pub_type： 杂志文章
doi：10.1016/j.inhe.2009.08.001
更新日期：2009-12-01 00:00:00
