Postural control, falls and fear of falling in people with multiple sclerosis without mobility aids.

Abstract:

:The purpose of the study was to determine the relationship between static postural control parameters to fear of falling and falling history in people with multiple sclerosis (MS) without mobility assistive devices. One-hundred and seven relapsing-remitting patients diagnosed with MS, 62 women aged 42.8 (S.D.=12.0), participated in this investigation. Participants were divided into groups based on fall history; 47 had no history during the past 6 months and 60 had a history of at least one fall within the same period. Static postural control parameters were obtained from the Zebris FDM-T Treadmill (zebris® Medical GmbH, Germany). The patient's self-reported questionnaire, the Falls Efficacy Scale International (FES-I), was used to assess the level of concern relating to falls. People with MS classified as fallers exhibited increased center of pressure (CoP) path length, sway velocity and greater overall sway area. CoP path length performed with eyes open was found to explain 42% of the variance related to at least one fall during the past six months; R(2)=0.424, χ(2)(1)=40.727, P<0.01. The correlation between the FES-I and CoP path length was 0.620 (P<0.001). Measurement of the CoP trajectories with instrumented posturography should be considered in managing fall risk in the MS population.

journal_name

J Neurol Sci

authors

Kalron A,Achiron A

doi

10.1016/j.jns.2013.09.029

subject

Has Abstract

pub_date

2013-12-15 00:00:00

pages

186-90

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(13)02938-9

journal_volume

335

pub_type

杂志文章
  • Apolipoprotein E epsilon4 allele frequency in elderly depressed patients with and without cerebrovascular disease.

    abstract::Late-onset depression (LOD) could be a very early manifestation of Alzheimer's disease (AD), although contradictory results have been reported. Cerebrovascular disease (CVD) may favor the development of LOD, and that the particular forms of vascular depression should be individualized. The Apolipoprotein E (ApoE) epsi...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2007.01.038

    authors: Traykov L,Bayle AC,Latour F,Lenoir H,Seux ML,Hanon O,Péquignot R,Bert P,Moulin F,Cantegreil I,Wenisch E,Batouche F,Mehrabian S,Rotrou Jd,Rigaud AS

    更新日期:2007-06-15 00:00:00

  • Apolipoprotein E polymorphisms status in Iranian patients with multiple sclerosis.

    abstract:BACKGROUND:Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Evidences linking apolipoprotein E (APOE) to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggest that it may be relevant in MS. The main goal of this study was to determine whet...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2012.05.050

    authors: Rafiei M,Zarif Yeganeh M,Sheikholeslami S,Gozalpour E,Ghaffarpour M,Hedayati M

    更新日期:2012-09-15 00:00:00

  • Inhibition of synaptosomal [3H]glutamate uptake and [3H]glutamate binding to plasma membranes from brain of young rats by glutaric acid in vitro.

    abstract::Synaptosomes and plasma membrane preparations from brain of 30-day-old rats were incubated with glutaric acid at final concentrations ranging from 10 nM to 1 mM for the determination of glutamate uptake and binding, respectively. [3H]Glutamate uptake into synaptosomes was inhibited by approximately 50% by 1 mM glutari...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(99)00307-x

    authors: Porciúncula LO,Dal-Pizzol A Jr,Coitinho AS,Emanuelli T,Souza DO,Wajner M

    更新日期:2000-02-15 00:00:00

  • Sleep disordered breathing in facioscapulohumeral muscular dystrophy.

    abstract::Facioscapulohumeral muscular dystrophy (FSHD) is one of the most frequent forms of muscular dystrophy. The aims of this study were: 1) to evaluate the prevalence of sleep disordered breathing (SDB) in patients with FSHD; 2) to define the sleep-related respiratory patterns in FSHD patients with SDB; and 3) to find the ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2009.05.014

    authors: Della Marca G,Frusciante R,Dittoni S,Vollono C,Buccarella C,Iannaccone E,Rossi M,Scarano E,Pirronti T,Cianfoni A,Mazza S,Tonali PA,Ricci E

    更新日期:2009-10-15 00:00:00

  • Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19.

    abstract::We evaluated the incidence, distribution, and histopathologic correlates of microvascular brain lesions in patients with severe COVID-19. Sixteen consecutive patients admitted to the intensive care unit with severe COVID-19 undergoing brain MRI for evaluation of coma or neurologic deficits were retrospectively identif...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2021.117308

    authors: Conklin J,Frosch MP,Mukerji SS,Rapalino O,Maher MD,Schaefer PW,Lev MH,Gonzalez RG,Das S,Champion SN,Magdamo C,Sen P,Harrold GK,Alabsi H,Normandin E,Shaw B,Lemieux JE,Sabeti PC,Branda JA,Brown EN,Westover MB,Huan

    更新日期:2021-01-15 00:00:00

  • Increased interhemispheric resting-state functional connectivity in paroxysmal kinesigenic dyskinesia: a resting-state fMRI study.

    abstract:PURPOSE:Paroxysmal kinesigenic dyskinesia (PKD) is a rare movement disorder. The underlying neural mechanisms have not been fully understood. This study aimed to examine the alteration of resting-state functional connectivity (RSFC) between interhemispheric homotopic regions in PKD using a technique called "voxel-mirro...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.02.046

    authors: Ren J,Lei D,Yang T,An D,Xiao F,Li L,Huang X,Gong Q,Zhou D

    更新日期:2015-04-15 00:00:00

  • Relationship between gray matter volume and cognitive learning in CIS patients on disease-modifying treatment.

    abstract:BACKGROUND:Repeated administration of Paced Auditory Serial Addition Test (PASAT) results in a considerable learning effect in short- or long-term follow-up studies. However, the relationship between PASAT learning and changes in magnetic resonance imaging (MRI) parameters is yet to be investigated. OBJECTIVES:The aim...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2014.10.002

    authors: Uher T,Benedict RH,Horakova D,Bergsland N,Dusankova JB,Tyblova M,Ramasamy DP,Seidl Z,Vaneckova M,Krasensky J,Havrdova E,Zivadinov R

    更新日期:2014-12-15 00:00:00

  • Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies.

    abstract::HS1-associated protein X-1 (HAX-1) and presenilin-associated rhomboid-like protein (PALR) were reported to play an important role in the activation of HtrA2/Omi, which is also designated PARK13, in the mitochondria. To elucidate the role of HAX-1 and PARL in patients with Parkinson's disease (PD) and dementia with Lew...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2020.116928

    authors: Kawamoto Y,Ayaki T,Urushitani M,Ito H,Takahashi R

    更新日期:2020-08-15 00:00:00

  • Clinical comparison between AVED patients with 744 del A mutation and Friedreich ataxia with GAA expansion in 15 Moroccan families.

    abstract::Fifteen Moroccan families with a phenotype resembling Friedreich Ataxia (FA) were studied. Seven families (13 patients) had the 744 del A mutation in the alpha-tocopherol transfer protein (alpha-TTP) gene, characteristic of ataxia with vitamin E deficiency (AVED). The other eight families (16 patients) had GAA expansi...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(02)00057-6

    authors: Benomar A,Yahyaoui M,Meggouh F,Bouhouche A,Boutchich M,Bouslam N,Zaim A,Schmitt M,Belaidi H,Ouazzani R,Chkili T,Koenig M

    更新日期:2002-06-15 00:00:00

  • External carotid artery branches involvement in reversible cerebral vasoconstriction syndrome.

    abstract::Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by segmental vasoconstriction and dilatation of intracranial arteries, usually revealed by headaches, which spontaneously resolve in few weeks. We report a patient with RCVS, revealed by thunderclap headaches, involving both internal and external ca...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2011.09.033

    authors: Melki E,Denier C,Théaudin-Saliou M,Sachet M,Ducreux D,Saliou G

    更新日期:2012-02-15 00:00:00

  • A serial study of regional cerebral blood flow deficits in patients with left anterior thalamic infarction: anatomical and neuropsychological correlates.

    abstract::Thalamic damage is associated with a variety of neuropsychological dysfunctions, as well as strategic infarct dementia. However, only a limited number of reports in the medical literature have discussed the correlation between the clinical findings and the specific functional changes observed on images. We investigate...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2007.09.016

    authors: Shim YS,Kim JS,Shon YM,Chung YA,Ahn KJ,Yang DW

    更新日期:2008-03-15 00:00:00

  • Adult-onset spastic paraparesis: an approach to diagnostic work-up.

    abstract::Adult-onset, chronic progressive spastic paraparesis may be due to a large number of causes and poses a diagnostic challenge. There are no recent evidence-based guidelines or comprehensive reviews to help guide diagnostic work-up. We survey the literature on chronic progressive spastic paraparesis, with special emphas...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.jns.2014.09.015

    authors: Zhovtis Ryerson L,Herbert J,Howard J,Kister I

    更新日期:2014-11-15 00:00:00

  • Clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis in varying age groups: A cohort study in China.

    abstract:PURPOSE:To investigate the clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-ON) in patients with varying ages of onset in China. METHODS:Patients displaying symptoms of MOG-ON were recruited from the Neuro-ophthalmology Department in the Chinese Peo...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2019.03.014

    authors: Song H,Zhou H,Yang M,Xu Q,Sun M,Wei S

    更新日期:2019-05-15 00:00:00

  • Retrospective analysis of parkinsonian patients exhibiting normal (123)I-MIBG cardiac uptake.

    abstract:BACKGROUND:Although most patients with Parkinson's disease (PD) show decreased cardiac (123)I-metaiodobenzylguanidine (MIBG) uptake, some exhibit normal uptake. We evaluated the clinical characteristics of such patients. METHODS:We enrolled 154 non-demented patients showing parkinsonism with normal cardiac MIBG uptake...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.10.059

    authors: Mizutani Y,Ito S,Murate K,Hirota S,Fukui T,Hikichi C,Ishikawa T,Shima S,Ueda A,Kizawa M,Asakura K,Mutoh T

    更新日期:2015-12-15 00:00:00

  • Increased amyloid beta protein levels in children and adolescents with Down syndrome.

    abstract:BACKGROUND:Persons with Down syndrome (DS) (40 years and older) have neuropathological changes characteristic of Alzheimer disease (AD). Soluble forms of amyloid beta (Abeta) peptide generated from amyloid precursor protein (APP) end at C-terminal residues 40 and 42. The presence of the apolipoprotein E (ApoE) epsilon4...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2006.12.010

    authors: Mehta PD,Capone G,Jewell A,Freedland RL

    更新日期:2007-03-15 00:00:00

  • Variation in ischemic stroke frequency in Japan by season and by other variables.

    abstract:BACKGROUND AND PURPOSE:It is unclear whether acute ischemic stroke exhibits a seasonal pattern in Japan. The aim of the present study was to elucidate seasonal differences in acute ischemic stroke. METHODS:Our study enrolled 12,660 patients with ischemic stroke (7943 men, 4717 women; mean age, 70.1 years, S.D. 11.5; m...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2004.07.002

    authors: Ogata T,Kimura K,Minematsu K,Kazui S,Yamaguchi T,Japan Multicenter Stroke Investigators' Collaboration.

    更新日期:2004-10-15 00:00:00

  • Steroids and brain atrophy in multiple sclerosis.

    abstract::In this review, we focus on different pathogenetic mechanisms of corticosteroids that induce short- and long-term brain volume fluctuations in a variety of systemic conditions and disorders, as well as on corticosteroid-induced immunomodulatory, immunosuppressive and anti-inflammatory mechanisms that contribute to the...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.jns.2005.03.006

    authors: Zivadinov R

    更新日期:2005-06-15 00:00:00

  • Short-term motor improvement after sub-threshold 5-Hz repetitive transcranial magnetic stimulation of the primary motor hand area in Parkinson's disease.

    abstract::Ten unmedicated patients with Parkinson's disease received sub-threshold 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the primary motor hand area (M1(HAND)) contralaterally to the more affected upper limb. Compared to a midfrontal sham-rTMS, real-rTMS over M1(HAND) was associated with a significant de...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0022-510x(00)00370-1

    authors: Siebner HR,Rossmeier C,Mentschel C,Peinemann A,Conrad B

    更新日期:2000-09-15 00:00:00

  • Sensitivity and specificity of cerebrospinal fluid CXCL13 for diagnosing Lyme neuroborreliosis - a study on 1410 patients and review of the literature.

    abstract:INTRODUCTION:The B-cell chemoattractant CXCL13 has been suggested as a cerebrospinal fluid (CSF) biomarker for Lyme neuroborreliosis (LNB). Our aim was to substantiate the value of CXCL13 in a large unselected cohort and determine a practical cut-off value to diagnose LNB. METHODS:We retrospectively studied clinical a...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2020.116843

    authors: Lintner H,Hochgatterer-Rechberger P,Pischinger B,Seier J,Vollmann P,Haushofer A,Rittner H,Sommer C,Topakian R

    更新日期:2020-07-15 00:00:00

  • Virus antibodies in the cerebrospinal fluid of multiple sclerosis patients detected with ELISA tests.

    abstract::The enzyme-linked immunosorbent assay (ELISA) was used to determine levels of specific IgG antibodies against measles, rubella, vaccinia, corona (OC43) and mumps viruses in cerebrospinal fluid (CSF) and serum of 18 patients with clinically definite multiple sclerosis (MS), 8 patients with optic neuritis (ON), 27 patie...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(82)90031-4

    authors: Leinikki P,Shekarchi I,Iivanainen M,Taskinen E,Holmes KV,Madden D,Sever JL

    更新日期:1982-12-01 00:00:00

  • Longitudinally extensive transverse myelitis immune-mediated in aquaporin-4 antibody negative patients: Disease heterogeneity.

    abstract:BACKGROUND:Longitudinally extensive transverse myelitis (LETM) is a frequent manifestation of neuromyelitis optica spectrum disorder (NMOSD). However, it can also occur in other immune-mediated diseases of the central nervous system (CNS). Positive aquoporin-4 antibodies (AQP4-ab) predict higher relapse rate after LETM...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2016.12.033

    authors: Carnero Contentti E,Hryb JP,Morales S,Gomez A,Chiganer E,Di Pace JL,Lessa C,Perassolo M

    更新日期:2017-02-15 00:00:00

  • Erythrocyte membrane abnormalities in patients with amyotrophic chorea with acanthocytosis. Part 1. Spin labeling studies and lipid analyses.

    abstract::Low fluidity was observed in the erythrocyte membranes of familial chorea-acanthocytosis by spin labeling with 12NS. The high content of the saturated fatty acids support the finding of low fluidity. Other lipid contents (cholesterol and phospholipids) and the cholesterol/phospholipid ratio were within normal ranges. ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(85)90096-6

    authors: Oshima M,Osawa Y,Asano K,Saito T

    更新日期:1985-05-01 00:00:00

  • Axonal degeneration in the pathogenesis of multiple sclerosis.

    abstract::Axonal degeneration plays an important role in the accumulation of disability in patients with multiple sclerosis (MS). Pathological studies have demonstrated axonal damage, particularly in areas of acute inflammation and demyelination, and in chronic lesions. Axonal loss and its progression, which is associated with ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/s0022-510x(99)00178-1

    authors: Silber E,Sharief MK

    更新日期:1999-11-15 00:00:00

  • Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice.

    abstract::Long-term effects of MPTP on striatal dopamine (DA) content and the influence of aging on the recovery were investigated in mice. Male C57BL/6J mice, young (2-month-old) and mature (10-month-old), were used. Two different dosage schedules of MPTP, i.e., 4 doses subcutaneous injections of 20 mg/kg each, and 4 doses sub...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(87)90125-0

    authors: Saitoh T,Niijima K,Mizuno Y

    更新日期:1987-02-01 00:00:00

  • Neurotologic manifestations of the fibromyalgia syndrome.

    abstract::The purpose was to assess otologic symptoms, and audiologic and vestibular findings in fibromyalgia (FM) syndrome. Twenty-four female patients with FM syndrome (FMS) were included in the study. The assessments were based on history, physical examination, audiometry, bithermal caloric testing and auditory brainstem res...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(02)00032-1

    authors: Bayazit YA,Gürsoy S,Ozer E,Karakurum G,Madenci E

    更新日期:2002-04-15 00:00:00

  • Impaired modulation of tonic muscle activities and H-reflexes in the soleus muscle during standing in patients with Parkinson's disease.

    abstract::The presence of postural disturbance in patients with Parkinson's disease (PD) was assessed by the displacement of the centre of foot pressure (CFP) and by changes in the amplitude of the soleus H-reflex when patients maintained an upright standing posture, followed by a forward-leaning posture. Thirteen patients and ...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0022-510x(97)00175-5

    authors: Hayashi R,Tokuda T,Tako K,Yanagisawa N

    更新日期:1997-12-09 00:00:00

  • A novel A781V mutation in the CSF1R gene causes hereditary diffuse leucoencephalopathy with axonal spheroids.

    abstract::We report a family with a novel CSF1R mutation causing hereditary diffuse leucoencephalopathy with axonal spheroids. Family members presented with neuropsychiatric and behavioural symptoms, with subsequent development of motor symptoms and gait disturbance. MRI brain showed extensive white matter change with a frontal...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2013.06.007

    authors: Ahmed R,Guerreiro R,Rohrer JD,Guven G,Rossor MN,Hardy J,Fox NC

    更新日期:2013-09-15 00:00:00

  • Respiration during sleep in Huntington's chorea.

    abstract::In view of recent reports on lower brainstem dysfunction in Huntington's chorea, we studied respiration during sleep in 12 patients with Huntington's chorea (HC) and in controls. There were no statistically significant differences between patients and controls with respect to apnea periods, respiratory frequency and t...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(88)90174-8

    authors: Bollen EL,Den Heijer JC,Ponsioen C,Kramer C,Van der Velde EA,Van Dijk JG,Roos RA,Kamphuisen HA,Buruma OJ

    更新日期:1988-03-01 00:00:00

  • Electron-microscopic X-ray microanalysis of normal and diseased human muscle.

    abstract::Electron-microscopic X-ray microanalysis has been used to compare elemental concentrations in specific organelles in normal and diseased human muscle. An elevated calcium to phosphorus ratio has been found in both myonuclei and interstitial cell nuclei in diseased muscle compared with controls. Preliminary observation...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(77)90129-0

    authors: Maunder CA,Yarom R,Dubowitz V

    更新日期:1977-09-01 00:00:00

  • Antibodies against myelin oligodendrocyte glycoprotein in the cerebrospinal fluid of multiple sclerosis patients.

    abstract::Antibodies against myelin oligodendrocyte glycoprotein (MOG) mediate demyelination in experimental autoimmune encephalomyelitis (EAE) in different animal species and are implicated in the immunopathogenesis of multiple sclerosis (MS). In order to evaluate the anti-MOG response, we have analyzed the cerebrospinal fluid...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(03)00066-2

    authors: Markovic M,Trajkovic V,Drulovic J,Mesaros S,Stojsavljevic N,Dujmovic I,Mostarica Stojkovic M

    更新日期:2003-07-15 00:00:00