Characterization of single α-tracks by photoresist detection and AFM analysis-focus on biomedical science and technology.

abstract：:Tumor motion is a particular concern for a complex treatment modality such as helical tomotherapy, where couch position, gantry rotation and MLC leaf opening all change with time. In the present study, we have investigated the impact of tumor motion for helical tomotherapy, which could result in three distinct motion-...

journal_title：Physics in medicine and biology

authors： Kim B,Chen J,Kron T,Battista J

更新日期：2009-10-07 00:00:00

abstract：:Medical imaging using single gamma-ray-emitting radionuclides typically makes use of parallel hole collimators or pinholes in order to achieve good spatial resolution. However, a tradeoff in sensitivity is inherent in the use of a collimator, and modern preclinical single photon emission computed tomography (SPECT) sy...

journal_title：Physics in medicine and biology

authors： Mitchell GS,Cherry SR

更新日期：2009-03-07 00:00:00

abstract：:Coronary computed tomography angiography (cCTA) is a commonly used imaging modality for the evaluation of coronary artery disease. cCTA is generally reconstructed in multiple cardiac phases because different coronary arteries may be better visualized in some phases than in others due to the periodic cardiac motion. We...

journal_title：Physics in medicine and biology

authors： Hadjiiski L,Zhou C,Chan HP,Chughtai A,Agarwal P,Kuriakose J,Kazerooni E,Wei J,Patel S

更新日期：2014-08-21 00:00:00

abstract：:The goals of this study were (1) to characterize the optical artefacts affecting measurement accuracy in a volumetric liquid scintillator detector, and (2) to develop methods to correct for these artefacts. The optical artefacts addressed were photon scattering, refraction, camera perspective, vignetting, lens distort...

journal_title：Physics in medicine and biology

authors： Robertson D,Hui C,Archambault L,Mohan R,Beddar S

更新日期：2014-01-06 00:00:00

abstract：:Today, new single photon emission computed tomography (SPECT) reconstruction techniques rely on accurate Monte Carlo (MC) simulations to optimize reconstructed images. However, existing MC scintillation camera models which usually include an accurate description of the collimator and crystal, lack correct implementati...

journal_title：Physics in medicine and biology

authors： Rault E,Staelens S,Van Holen R,De Beenhouwer J,Vandenberghe S

更新日期：2011-01-07 00:00:00

abstract：:An optimized configuration of multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT simultaneously. In this study, an optimization strategy of the multi-pinhole configuration with a small detector is proposed for mouse cardiac imaging. A 14 mm-diameter spherical field-of-view (...

journal_title：Physics in medicine and biology

authors： Lee MW,Lin WT,Chen YC

更新日期：2015-01-21 00:00:00

abstract：:Deformable image registration (DIR) is increasingly used in radiotherapy applications and provides the basis for a previously described model of patient-specific respiratory motion. We examine the accuracy of a DIR algorithm and a motion model with respiration-correlated CT (RCCT) images of software phantom with known...

journal_title：Physics in medicine and biology

authors： Liu F,Hu Y,Zhang Q,Kincaid R,Goodman KA,Mageras GS

更新日期：2012-05-07 00:00:00

abstract：:Incorrect prediction of skin dose in external beam radiotherapy (EBR) can have normal tissue complication such as acute skin desquamation and skin necrosis. The absorbed dose of skin should be evaluated within basal layer, placed between the epidermis and dermis layers. However, current treatment planning systems (TPS...

journal_title：Physics in medicine and biology

authors： Cheon BW,Yoo DH,Shin WG,Choi HJ,Park HJ,Kim JI,Min CH

更新日期：2019-08-14 00:00:00

abstract：:In this paper, a coupled radiative transfer equation and diffusion approximation model is extended for light propagation in turbid medium with low-scattering and non-scattering regions. The light propagation is modelled with the radiative transfer equation in sub-domains in which the assumptions of the diffusion appro...

journal_title：Physics in medicine and biology

authors： Tarvainen T,Vauhkonen M,Kolehmainen V,Arridge SR,Kaipio JP

更新日期：2005-10-21 00:00:00

abstract：:The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and w...

journal_title：Physics in medicine and biology

authors： Craft D,Halabi T,Bortfeld T

更新日期：2005-12-21 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:It is difficult to test near-infrared spectrophotometry instruments in vivo. Therefore we constructed a liquid phantom which mimics the neonatal head. It consists of a spherical 3.5 mm thick layer of silicone rubber simulating skin and bone and a 0.5 mm thick clear layer of polypropylene imitating cerebrospinal fluid....

journal_title：Physics in medicine and biology

authors： Wolf M,Keel M,Dietz V,von Siebenthal K,Bucher HU,Baenziger O

更新日期：1999-07-01 00:00:00

abstract：:The 'EXACT3D' positron tomograph, which is now in routine clinical research use, was developed with the aim of achieving unprecedented sensitivity, high spatial and temporal resolution and simplicity of design using proven detector technology. It consists of six rings of standard detector blocks (CTI/Siemens EXACT HR+...

journal_title：Physics in medicine and biology

authors： Spinks TJ,Jones T,Bloomfield PM,Bailey DL,Miller M,Hogg D,Jones WF,Vaigneur K,Reed J,Young J,Newport D,Moyers C,Casey ME,Nutt R

更新日期：2000-09-01 00:00:00

abstract：:Measurements of lung nodule volume with multi-detector computed tomography (MDCT) have been shown to be more accurate and precise compared to conventional lower dimensional measurements. Quantifying the size of lesions is potentially more difficult when the object-to-background contrast is low as with lesions in the l...

journal_title：Physics in medicine and biology

authors： Li Q,Gavrielides MA,Zeng R,Myers KJ,Sahiner B,Petrick N

更新日期：2015-01-21 00:00:00

abstract：:The energy dependence of the luminance ratio due to scattered and primary radiation has been determined for four types of X-ray intensifying screens. A water phantom of 30 cm X 30 cm X 20 cm was used as the scattering medium. Ten narrow band X-ray spectra were used as incident radiation: the mean energies of these spe...

journal_title：Physics in medicine and biology

authors： Koedooder K,Venema HW

更新日期：1984-10-01 00:00:00

abstract：:The effect of temperature on the optical properties of human dermis and subdermis as a function of near-infrared wavelength has been studied between 25 degrees C and 40 degrees C. Measurements were performed ex vivo on a total of nine skin samples taken from the abdomen of three individuals. The results show a reprodu...

journal_title：Physics in medicine and biology

authors： Laufer J,Simpson R,Kohl M,Essenpreis M,Cope M

更新日期：1998-09-01 00:00:00

abstract：:This study investigates the oxygen mass transport in the region around the human carotid bifurcation, particularly addressing the effects of bifurcation geometry and pulsatile blood flow on the oxygen transport between the blood flow and artery wall tissue, coupled with the metabolic oxygen consumption and oxygen diff...

journal_title：Physics in medicine and biology

authors： Tada S

更新日期：2010-07-21 00:00:00

abstract：:In external beam radiation therapy, radioactive beams offer the best clinical solution to simultaneously treat and in vivo monitor the dose delivery and tumor response using PET or PET-CT imaging. However, difficulties mainly linked to the low production efficiency have so far limited their use. This study is devoted ...

journal_title：Physics in medicine and biology

authors： Lazzeroni M,Brahme A

更新日期：2011-03-21 00:00:00

abstract：:The stochastic nature of cavitation implies visualization of the cavitation cloud in real-time and in a discriminative manner for the safe use of focused ultrasound therapy. This visualization is sometimes possible with standard echography, but it strongly depends on the quality of the scanner, and is hindered by diff...

journal_title：Physics in medicine and biology

authors： Arnal B,Baranger J,Demene C,Tanter M,Pernot M

更新日期：2017-02-07 00:00:00

abstract：:This work modified the commonly used Monte Carlo tool package GATE by developing a new 'multiPatchPET' system so that GATE users can easily simulate PET systems with irregular geometries. The motivation was to design a brain PET scanner with high sensitivity. It is known that compact PET scanners with a large solid co...

journal_title：Physics in medicine and biology

authors： Chen G,Weng F,Hong X,Tao W,Zhao Z,Peng Q,Huang Q

更新日期：2018-09-06 00:00:00

abstract：:There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

journal_title：Physics in medicine and biology

authors： Renner F,Wulff J,Kapsch RP,Zink K

更新日期：2015-10-07 00:00:00

abstract：:Prompt γ-ray imaging with a knife-edge shaped slit camera provides the possibility of verifying proton beam range in tumor therapy. Dedicated experiments regarding the characterization of the camera system have been performed previously. Now, we aim at implementing the prototype into clinical application of monitoring...

journal_title：Physics in medicine and biology

authors： Priegnitz M,Barczyk S,Nenoff L,Golnik C,Keitz I,Werner T,Mein S,Smeets J,Vander Stappen F,Janssens G,Hotoiu L,Fiedler F,Prieels D,Enghardt W,Pausch G,Richter C

更新日期：2016-11-21 00:00:00

abstract：:Compromises in the design of a positron emission tomography (PET) insert for a magnetic resonance imaging (MRI) system should minimize the deterioration of image quality in both modalities, particularly when simultaneous demanding acquisitions are performed. In this work, the advantages of using individually read-out ...

journal_title：Physics in medicine and biology

authors： Omidvari N,Topping G,Cabello J,Paul S,Schwaiger M,Ziegler SI

更新日期：2018-05-01 00:00:00

abstract：:A complete characterization of spongiosa (bone marrow plus trabecular bone) is required to calculate the absorbed dose to active bone marrow. Due to the complex microanatomy, it is necessary to apply non-conventional imaging methods in nuclear medicine. The aim of this study is validating a phantomless quantification ...

journal_title：Physics in medicine and biology

authors： Salas-Ramirez M,Tran-Gia J,Gbureck U,Kosmala A,Lassmann M

更新日期：2019-10-16 00:00:00

abstract：:Abdominal organ motion may lead to considerable uncertainties in pencil-beam scanning (PBS) proton therapy of pancreatic cancer. Beam gating, where irradiation only occurs in certain breathing phases in which the gating conditions are fulfilled, may be an option to reduce the interplay effect between tumor motion and ...

journal_title：Physics in medicine and biology

authors： Dolde K,Naumann P,Dávid C,Kachelriess M,Lomax AJ,Weber DC,Saito N,Burigo LN,Pfaffenberger A,Zhang Y

更新日期：2019-04-10 00:00:00

abstract：:Compton scatter poses a significant threat to volumetric x-ray computed tomography, bringing cupping and streak artefacts thus impacting qualitative and quantitative imaging procedures. To perform appropriate scatter compensation, it is necessary to estimate the magnitude and spatial distribution of x-ray scatter. The...

journal_title：Physics in medicine and biology

authors： Akbarzadeh A,Ay MR,Ghadiri H,Sarkar S,Zaidi H

更新日期：2010-04-21 00:00:00

abstract：:Recently, the Task Group 103 of the International Commission on Radiological Protection (ICRP) has developed new mesh-type reference computational phantoms (MRCPs) for adult male and female. When compared to the current voxel-type reference computational phantoms in ICRP Publication 110, the MRCPs have several advanta...

journal_title：Physics in medicine and biology

authors： Lee H,Yeom YS,Nguyen TT,Choi C,Han H,Shin B,Zhang X,Kim CH,Chung BS,Zankl M

更新日期：2019-02-05 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is an effective procedure for patients with heart failure but 30% of patients do not respond. This may be due to sub-optimal placement of the left ventricular (LV) lead. It is hypothesized that the use of cardiac anatomy, myocardial scar distribution and dyssynchrony information...

journal_title：Physics in medicine and biology

authors： Ma YL,Shetty AK,Duckett S,Etyngier P,Gijsbers G,Bullens R,Schaeffter T,Razavi R,Rinaldi CA,Rhode KS

更新日期：2012-05-21 00:00:00

abstract：:In magnetic drug targeting a chemotherapeutic agent is bound to coated magnetic nanoparticles, which are administered to the blood vessel system and subsequently focused by an external applied magnetic field. The optimization of intra-arterial magnetic drug targeting (MDT) requires detailed knowledge about the biodist...

journal_title：Physics in medicine and biology

authors： Richter H,Wiekhorst F,Schwarz K,Lyer S,Tietze R,Alexiou Ch,Trahms L

更新日期：2009-09-21 00:00:00

abstract：:Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2006-12-07 00:00:00