[Visual outcome in patients with macroprolactinoma treated with dopamine agonists].

Abstract:

BACKGROUND:Dopamine agonists (DA) effectively reduce tumor size of macroprolactinomas, with the consequent improvement of eventual visual impairment. AIM:To study the visual outcomes in patients with macroprolactinoma treated with DA. MATERIAL AND METHODS:Retrospective cohort study which included patients with macroprolactinoma controlled at a Neuro-endocrinology and Neuro-ophthalmology Department between 1997 and 2011, and treated exclusively with DA (bromocriptine or cabergoline). Patients who were operated or had previous radiotherapy and those with an incomplete follow up, were excluded. We analyzed and compared the visual status before and after the beginning of DA treatment. RESULTS:Thirty one patients aged 8 to 59 years, were included. Eighteen patients (58%) had visual impairment at the moment of diagnosis (group 1) and 13 had no alterations (group 2). Mean follow up was 36.5 months. Fifteen patients from group 1 (83%) had visual improvement, two remained stable (11 %) and one had a visual deterioration (6%). In group 2, only one non-compliant patient had a visual deterioration. CONCLUSIONS:DAs are effective in the management of neuro-ophthalmic complications associated to macroprolactinomas and should be considered as first choice therapy in these tumors.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Cuevas JL,Fernández V,Rojas D,Wohllk N,González O,Torche E

doi

10.4067/S0034-98872013000600001

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

687-94

issue

6

eissn

0034-9887

issn

0717-6163

pii

S0034-98872013000600001

journal_volume

141

pub_type

杂志文章
  • [Polymorphic reticulosis: a type of lymphoma? Report of 3 cases].

    abstract::Three patients seen at the Medicine Department of Del Salvador Hospital between 1986 and 1990 are reported. All had a history of purulent or bloody nasal discharge and recurrent sinusitis, before the appearance of progressive and painful destructive phenomena that affected the rhino faucial region. The diagnosis was m...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Wainstein E,Vergara I,Segovia A,Guzmán L

    更新日期:1992-11-01 00:00:00

  • [Airway tridimensional printing].

    abstract::Tridimensional printing is becoming relevant in medicine, specially in surgical and interventional specialties. We review the technical aspects and clinical application of airway tridimensional printing. Using this technique, simulation models for bronchoscopy and models for diagnostic and therapeutic procedures such ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872019001001315

    authors: Gando S,Labarca G,Majid A,Folch E,Mehta HJ,Jantz M,Fernandez-Bussy S

    更新日期:2019-10-01 00:00:00

  • [Cervical polyadenopathy due to Kikuchi and Fujimoto disease].

    abstract::Kikuchi and Fujimoto disease is a benign subacute necrotizing lymphadenitis, probably associated to a viral infection, that affects mostly young Asian women. We report a 19 years old women, with a vast familiar history of thyroid disease (three uncles with papillary thyroid carcinoma and one with a Hashimoto thyroidit...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: López JM,Alvarez M,Cárdenas IE,Gallegos M

    更新日期:1997-03-01 00:00:00

  • [Cultural and trivial knowledge among Chilean university students].

    abstract:BACKGROUND:Culture is defined by the Webster's dictionary as acquaintance with and taste in fine arts, humanities, and broad aspects of science as distinguished from vocational and technical skills. AIM:To assess the general cultural knowledge of university students. MATERIAL AND METHODS:A test containing 58 question...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872010000300005

    authors: Vargas C NA,Pinochet T D,Juárez E P

    更新日期:2010-03-01 00:00:00

  • [Multisystemic involvement in obstructive sleep apnea].

    abstract::Obstructive Sleep Apnea (OSA) is characterized by repetitive upper airway collapse with apnea/hypopnea and recurrent hypoxia during sleep, which results in fragmented sleep and intermittent drops in arterial blood oxygen saturation (hypoxemia). Several dysfunctions of neurocognitive, endocrine, cardiovascular, and met...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872014000600009

    authors: Labarca G,Cruz N R,Descalzi F

    更新日期:2014-06-01 00:00:00

  • [Identification of B and F human immunodeficiency virus subtypes in Chilean patients].

    abstract:BACKGROUND:Type I human immunodeficiency virus (HIV) is characterized by a great genetic variability. There are three groups of virus throughout the world: O, N and M. Group M is responsible for AIDS pandemic and is subdivided in 9 genetic subtypes. Most viral strains in South America are subtype B. AIM:To determine t...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Ríos M,Villanueva C,San Martín C,Ramírez E

    更新日期:2003-07-01 00:00:00

  • [Acute severe pancreatitis. Analysis of mortality and morbidity].

    abstract::Sixty-three patients with severe acute pancreatitis have been studied. Pancreatitis was associated with biliary tract disease in 23 patients (36.5%) and with alcoholism in 21 (33.3%). It occurred post-operatively in 9, and was associated with other conditions in 10. We evaluated the Ranson prognostic signs (RPS) with ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Martínez J,Zúñiga A,Guzmán S,Llanos O,Rahmer A,Troncoso P,Escobar M

    更新日期:1991-06-01 00:00:00

  • [Undergraduate medical students' expectative of their desired profile as medical doctors].

    abstract:BACKGROUND:During the last few years, multiple new medical schools have emerged in Chile, associated to the constant preoccupation to provide a good quality medical care. This created the need to evaluate medical training programs and to open a discussion about the attributes that a good physician should have. AIM:To ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872006000800001

    authors: García-Huidobro D,Núñez F,Vargas P,Astudillo S,Hitschfeld M,Gennero R,Salvatierra L,Benavente A

    更新日期:2006-08-01 00:00:00

  • [Epidemiological profile of liver cirrhosis in Chile 1970-1992].

    abstract:BACKGROUND:Liver cirrhosis is an important public health problem in Chile. AIM:To review the main epidemiological features of liver cirrhosis in Chile in the last 22 years. METHODS:Review of yearbooks of mortality and causes of death of the Ministry of Health and Instituto Nacional de Estadísticas, review of hospital...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Serra I,Araneda J,Decinti E

    更新日期:1995-11-01 00:00:00

  • [Antimicrobial activity of actinomycetes isolated from aquatic environments in southern Chile].

    abstract:BACKGROUND:The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment. Actinomycetes are a ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000200003

    authors: Leiva S,Yáñez M,Zaror L,Rodríguez H,García-Quintana H

    更新日期:2004-02-01 00:00:00

  • [Clinical features of patients with Basedow Graves disease seen at a university hospital].

    abstract:BACKGROUND:Basedow Graves disease (BGD) is the leading cause of hyperthyroidism. The characteristics of patients seen at a university hospital may differ from those described in the general population. AIM:To describe the clinical features of patients with BGD seen at a university hospital. MATERIAL AND METHODS:Revie...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872017000400003

    authors: Lanas A,Díaz P,Eugenin D,González F,Cid P,Cordero F,Araya V,Liberman C,Barberan M,Gac P,Saldías N,Pineda P

    更新日期:2017-04-01 00:00:00

  • [Etiologic diagnosis of pneumonia in HIV-AIDS patients. Usefulness of fibrobronchoscopy].

    abstract:AIM:to assess the usefulness of fiberoptic bronchoscopy in the etiologic diagnosis of pulmonary infiltrates in patients with AIDS. PATIENTS AND METHODS:in 25 patients with AIDS and pneumonia, 31 fiberoptic bronchoscopies with bronchoalveolar lavage were performed; in 11 occasions, a transbronchial biopsy was also perf...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Henríquez A,Srur E,Giglio M,Fernández A,Cona E,Lorca M,García A,Northland R,Segovia J,Gutiérrez S

    更新日期:1993-03-01 00:00:00

  • [Inflammation as a common pathogenic factor in coronary artery disease and depression].

    abstract::A narrative review of the evidence regarding the role of inflammation in the pathophysiology of coronary heart disease and depression is presented. As a common pathogenic factor, inflammation could explain the frequent association of both diseases. We discuss the benefit of exercise and diet modifications in both cond...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872020000200224

    authors: Cavieres F Á

    更新日期:2020-02-01 00:00:00

  • [Predictive value of the ergometric test stress parameters for myocardial ischemia according to SPECT thallium-201 scintigraphy].

    abstract:BACKGROUND:Exercise EKG is used as the test of choice in the diagnosis of coronary artery disease. Classical parameters are angor and ST depression representing myocardial ischemia. AIM:To correlate exercise EKG parameters with SPECT 201Thallium to know their likelihood ratios for ischemia. PATIENTS AND METHODS:Two h...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Prat H,Massardo T,Jofré J,Vargas J,González P

    更新日期:1998-05-01 00:00:00

  • [Outcome of microbial invasion of amniotic cavity in the preterm premature rupture of membranes].

    abstract:BACKGROUND:Microbial invasion of amniotic cavity occurs in 30 to 50% of patients with premature membrane rupture. AIM:To determine the outcomes associated with microbial invasion of the amniotic cavity (MIAC) in patients with preterm premature rupture of membrane (pPROM). PATIENTS AND METHODS:One hundred thirty four ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005000100007

    authors: Ovalle S A,Gómez M R,Martínez T MA,Kakarieka W E,Fuentes G A,Aspillaga M C,Ferrand M P,Ramírez F C

    更新日期:2005-01-01 00:00:00

  • [Hemoptysis as the initial manifestation of Behçet's disease. Report of two cases].

    abstract::Arterial involvement in Behçet's disease (BD) is less common than venous lesions. The most commonly affected arteries are: the aorta, lower extremity arteries, mesenteric, femoral, coronary, renal, subclavian and pulmonary arteries. The rupture of pulmonary arteries is the main cause of death of patients with EB and t...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872018000400528

    authors: Abarca M,Santamarina M,Vergara C,Vega J

    更新日期:2018-04-01 00:00:00

  • [Wolff-Parkinson-White syndrome: late results of surgical treatment].

    abstract::We followed 25 patients operated on for Wolff-Parkinson-White syndrome between August 1985 and October 1989. Their mean age was 37 +/- 12 years and arrhythmia had been present for 5 to 30 years. A mean of 3.3 +/- 1.2 antiarrhythmic agents had failed in controlling recurrences. Tachycardia was orthodromic in 21 patient...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: González R,Morán S,Fajuri A,Irarrazabal MJ,Maturana G,Urzua J,Lema G,Espinoza R,Casanegra P

    更新日期:1990-08-01 00:00:00

  • [KRAS gene mutation in colorectal cancer].

    abstract:BACKGROUND:KRAS oncogene is involved in colorectal carcinogenesis in 22 to 45% of cases. AIM:To determine the frequency, types and distribution of KRAS mutations in colorectal cancer. MATERIAL AND METHODS:KRAS mutations studies were carried out in primary tumors and metastases of colo-rectal cancer from 56 women aged...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872013000900009

    authors: Roa I,Sánchez T,Majlis A,Schalper K

    更新日期:2013-09-01 00:00:00

  • [Indication of gastrojejunostomy in unresectable pancreatic cancer].

    abstract:BACKGROUND:Up to 20% of patients with pancreatic carcinoma subjected to a bilio digestive diversion, develop a delayed gastric emptying due to duodenal infiltration. However the role of prophylactic gastrojejunoanastomosis is not well defined. AIM:To compare the effects of gastrojejunoanastomosis performed as prophyla...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Espinoza R,Rivera M,Guzmán S

    更新日期:1999-01-01 00:00:00

  • [Selective use of glucocorticoids during the perioperative period of transsphenoidal surgery for pituitary tumors].

    abstract:BACKGROUND:There is consensus in promoting the selective use of glucocorticoids (GC) in the peri-operative period of transsphenoidal surgery (TE) for pituitary adenomas (PA). AIM:To evaluate the safety of a selective glucocorticoid administration protocol and the usefulness of immediate postoperative cortisol levels a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000900004

    authors: Carrasco CA,Villanueva G P

    更新日期:2014-09-01 00:00:00

  • [Scientific research: a cultural legacy].

    abstract::This is the conference given by Jorge Mardones, Emeritus Professor of the University of Chile on the occasion of receiving the Juvenal Hernández award. A biographical trace of Professor Mardones scientific career and its motivations, including his relation to outstanding Chilean scientists is included. A remembrance o...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Mardones J

    更新日期:1989-02-01 00:00:00

  • [Rising infant mortality in down syndrome in Chile from 1997 to 2013].

    abstract:BACKGROUND:Down syndrome (DS) is associated with higher child mortality especially due to cardiac malformations. AIM:To describe the trend in Chilean infant mortality in DS in the period 1997-2013 as compared to the general population without DS. MATERIAL AND METHODS:Raw data on infant deaths were extracted from the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016001100009

    authors: Donoso E,Vera C

    更新日期:2016-11-01 00:00:00

  • [Reproductive history of Chilean puerperal women hospitalized in a public hospital of the metropolitan region].

    abstract:BACKGROUND:Maternal and infantile morbidity is closely related to the features of women's reproductive history. AIM:To study the reproductive behavior of women hospitalized due to labor or abortion in a public maternity of Metropolitan Santiago. SUBJECTS AND METHODS:One thousand women were interviewed about their rep...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Henríquez R,Vargas N

    更新日期:1996-10-01 00:00:00

  • [Referral to rehabilitation services of patients discharged from a general hospital with a potentially disabling condition].

    abstract::Background Patients discharged from general hospitals with a potentially disabling condition can benefit in their recovery with the aid of physical medicine and rehabilitation services. Aim To determine the proportion of patients discharged from a general hospital with a potentially disabling condition, who were deriv...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872017001201541

    authors: Hofmann U N,Paolinelli G C,Castro L A

    更新日期:2017-12-01 00:00:00

  • [Evaluation of public health risk. A new instrument for environmental management in Chile].

    abstract::One of the main challenges in environmental management is to prevent the public health impact of projects that can cause pollution. To tackle this problem, the new Chilean bill on environmental management has defined the need to determine the potential health risks of a given Project. This paper gives a summary of the...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872011000800015

    authors: Matus C P

    更新日期:2011-08-01 00:00:00

  • [Human papilloma virus (HPV) typing in preneoplastic and neoplastic lesions of the uterine cervix in the IX region-Chile].

    abstract:BACKGROUND:Uterine cervical cancer (UCC) is an important public health problem in Chile. Although HPV infection has been established as the main cause of UCC, little is known of its frequency and distribution in our population. AIM:To determine the presence and frequency of viral genotypes in uterine cervical specimen...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Melo A,Montenegro S,Hooper T,Capurro I,Roa JC,Roa I

    更新日期:2003-12-01 00:00:00

  • [The medical history of Edgar Allan Poe].

    abstract::Edgar Allan Poe, one of the best American storytellers and poets, suffered an episodic behaviour disorder partially triggered by alcohol and opiate use. Much confusion still exists about the last days of his turbulent life and the cause of his death at an early age. Different etiologies have been proposed to explain h...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:10.4067/s0034-98872007000900019

    authors: Miranda C M

    更新日期:2007-09-01 00:00:00

  • [Possible perinatal determinants of morbidity in adult age].

    abstract::Recently, several groups have studied the influence of possible noxious elements present in the intrauterine environment which may favor the development of several diseases in the adult. There is evidence of an increased prevalence of some disorders in special risk groups of fetuses. In the small for gestational age p...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Aros S,Cassorla F

    更新日期:2001-03-01 00:00:00

  • [Evolution of internal medicine and its specialties in the last decades: an outward view].

    abstract::The development of the subspecialties of internal medicine in the western world is reviewed from a historical perspective, focusing on the case of the United States of America. During the last decades, changes both in society and in medicine as a whole have prompted a great dispersion of medical practice styles, not a...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Rosselot E

    更新日期:1996-04-01 00:00:00

  • [Renal artery thrombosis after withdrawal from anticoagulation therapy in a kidney transplant recipient with thrombophilia: report of one case].

    abstract::Kidney graft loss because arterial thrombosis is not common and is related to risk factors such as recurrent vascular hemodialysis access thrombosis, collagen-vascular disease, repeated miscarriage, diabetes mellitus and thrombophilia. Patients having this last disorder have an increased risk of repeated thrombosis in...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000100014

    authors: Vega S J,Goecke S H,Vásquez G A,Peña M A

    更新日期:2007-01-01 00:00:00