Abstract:
BACKGROUND:Predicting the function of transplanted kidneys would help clinicians in individualized medical interventions. We aimed to develop and validate a predictive tool for a future value of estimated glomerular filtration rate (eGFR) at upcoming visits. METHODS:We used static and time-dependent covariates as inputs of artificial neural network based prediction models for predicting an eGFR value for an upcoming visit. We included 675 kidney recipients, who received transplant in the Urmia kidney transplant center in 2001-2013 and were longitudinally cared for in 2001-2017. The first 75% of records of longitudinal data of each patient were used to develop the prediction models and the remaining last 25% for evaluating its performance. Models' performances were evaluated by Mean Square Error (MSE) and Mean Absolute Error (MAE). RESULTS:The development and validation datasets included 18,773 and 7038 records of historical data, respectively. The most accurate model included 3 static covariates of recipients' gender and donors' age and gender as well as 11 dynamic covariates of recipients including current age, time since transplant, serum creatinine, fasting blood sugar, weight and blood pressures available at each visit time. The performance of prediction models in the validation cohort was improved when history window of time dependent variables' recent values was increased from 1 to 10 (an MSE decline from 161 to 99). CONCLUSIONS:Our best performed model is able to dynamically predict a future eGFR value for kidney recipients' upcoming visits. Integrating such a clinical tool into daily workflow of outpatient clinics can potentially support clinicians in optimal and individualized decision makings.
journal_name
Int J Med Informjournal_title
International journal of medical informaticsauthors
Rashidi Khazaee P,Bagherzadeh J,Niazkhani Z,Pirnejad Hdoi
10.1016/j.ijmedinf.2018.09.012subject
Has Abstractpub_date
2018-11-01 00:00:00pages
125-133eissn
1386-5056issn
1872-8243pii
S1386-5056(18)30111-4journal_volume
119pub_type
杂志文章abstract:OBJECTIVE:The purpose of the research was to assess real-time location systems (RTLS) that have been implemented in U.S. hospitals. We examined the type of uses to which RTLS have been put, the degree of functionality of the various technologies and software, and the organizational effects of implementing RTLS. METHOD...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2012.07.001
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To investigate: (1) the annotation time savings by various active learning query strategies compared to supervised learning and a random sampling baseline, and (2) the benefits of active learning-assisted pre-annotations in accelerating the manual annotation process compared to de novo annotation. MATERIALS ...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2017.08.001
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To describe the kinds of unintended consequences related to the implementation of computerized provider order entry (CPOE) in the outpatient setting. DESIGN:Ethnographic and interview data were collected by an interdisciplinary team over a 7 month period at four clinics. MEASUREMENTS:Instances of unintended...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2006.05.017
更新日期:2007-06-01 00:00:00
abstract::With the growing concern about health issues and the emergence of online communities based on user-generated content (UGC), more and more people are participating in online health communities (OHCs) to exchange opinions and health information. This paper aims to examine whether and how male and female users behave dif...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2017.12.019
更新日期:2018-03-01 00:00:00
abstract::The introduction of computer-based information systems (ISs) in public health provides enhanced possibilities for service improvements and hence also for improvement of the population's health. Not least, new communication systems can help in the socialization and integration process needed between the different profe...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(02)00074-6
更新日期:2002-12-18 00:00:00
abstract::This paper reviews clinical decision support systems (CDSS) literature, with a focus on evaluation. The literature indicates a general consensus that clinical decision support systems are thought to have the potential to improve care. Evidence is more equivocal for guidelines and for systems to aid physicians with dia...
journal_title:International journal of medical informatics
pub_type: 杂志文章,评审
doi:10.1016/s1386-5056(01)00183-6
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:The drug information most commonly requested by patients is to learn more about potential adverse drug reactions (ADRs) of their drugs. Such information should be customizable to individual information needs. While approaches to automatically aggregate ADRs by text-mining processes and establishment of respe...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2019.103970
更新日期:2020-01-01 00:00:00
abstract::The process of generating a clinical referral for a patient, and the resulting transfer of information from the primary care physician to the specialist and back again, are key components in the struggle to deliver less costly and more effective clinical care. We have created a computer-based, outpatient clinical refe...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(99)00027-1
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether context-specific alerts for potassium-increasing drug-drug interactions (DDIs) in a clinical decision support system reduced the alert burden, increased alert acceptance, and had an effect on the occurrence of hyperkalemia. MATERIALS AND METHODS:In the pre-intervention period all alert...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2019.104013
更新日期:2020-01-01 00:00:00
abstract::This paper introduces the topic of this special issue: challenges for medical informatics in the 21st century. This paper discusses the nature of medical informatics. Some descriptions and definitions of medical informatics are reviewed. Then the research aspects of medical informatics are discussed. It is argued that...
journal_title:International journal of medical informatics
pub_type: 杂志文章,评审
doi:10.1016/S1386-5056(97)01253-7
更新日期:1997-03-01 00:00:00
abstract::This study evaluated the impact of telemedicine technology on the provision of neurosurgical health services. We focused on the differences between the use of real time audio-visual teleconferencing and teleradiology versus conventional telephone consultations in the referral of neurosurgical patients from a large dis...
journal_title:International journal of medical informatics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s1386-5056(01)00161-7
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVES:This paper has two objectives. First, it categorizes the Twitter handles tweeted flu related information based on the amount of replies and mentions within the Twitter network. The collected Twitter accounts are categorized as media, health related individuals, organizations, government, individuals with no ...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2016.04.009
更新日期:2016-07-01 00:00:00
abstract::This paper presents a computerised information system for the characterisation and analysis of the hospital admission flow of patients. Based on administrative data made available by the Ministry of Health of Brazil (DATASUS-MS), the system allows the representation of patients' flow from residence to hospital, as wel...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(00)00129-5
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:In this article we begin by connecting the concept of simplicity of user interfaces of information systems with that of usability, and the concept of complexity of the problem-solving in information systems with the concept of usefulness. We continue by stating "the usability axiom" of medical information ...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2006.05.039
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:Patients have the most to gain from reducing medical errors; yet, little research has been done to investigate the role they could or already do play in detecting and preventing errors in their own health care. The purpose of this study is to examine patient's role in detecting, preventing, and recovering from ...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2006.05.021
更新日期:2007-06-01 00:00:00
abstract::Can higher quality healthcare practices emerge from the development and use of a loosely integrated set of intranets? This paper examines that question through a series of empirical examples that draw on data from one healthcare organization that was part of a multi-year, multi-industry study of intranets. Some of thi...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2006.06.007
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:Nurses' work in hospital departments is highly collaborative and includes communication with a variety of actors. To further support nurses' communications, wireless phones, on which nurses receive both nurse calls and ordinary phone calls, have been introduced. However, while they ensure high availability...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2014.06.007
更新日期:2014-09-01 00:00:00
abstract::Single-switch communication is an effective auxiliary method for persons with disabilities. However, it is not easy to recognize the Morse codes typed by them. In our earlier proposed Morse code auto-recognition method, using the Least-Mean-Square (LMS) adaptive algorithm, it was demonstrated that the system could suc...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(97)00020-8
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:With increasing computerization of nursing records in Japan, standardization of nursing terminology is becoming imperative. Although some efforts have been made to formalize description of nursing practice in Japan with the International Classification of Nursing Practice (ICNP), lack of effective descriptio...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2006.02.006
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Documentation of medical treatment and observation of patients during evacuation from the point of injury to definitive treatment is important both for optimizing patient treatment and managing the evacuation process. The current practice in military medical field documentation uses paper forms and voice commun...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2007.01.006
更新日期:2008-02-01 00:00:00
abstract::For Medinfo '98, as an exercise in technological forecasting and analysis, we volunteered to project the direction of healthcare informatics into the next century. This paper is an extended discussion of that presentation. We open with the observation that healthcare informatics is merely one of the many endeavors tha...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(98)00161-0
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To identify factors that can enhance the use of e-consultation in primary care. We investigated the barriers, demands and motivations regarding e-consultation among patients with no e-consultation experience (non-users). METHODS:We used an online survey to gather data. Via online banners on 26 different webs...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2009.06.002
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Antimicrobial stewardship (AMS) programs aim to optimize antibiotic use and reduce inappropriate prescriptions through a panel of interventions. The implementation of clinical guidelines is a core strategy of AMS programs. Nevertheless, their dissemination and application remain low. Computeri...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2020.104233
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The objectives of this paper are: In this approach, the implementation of such a complex IT solution is considered a major redesign of the work system. The paper describes the Human Factor (HF) tasks embedded in the project lifecycle: (1) analysis and modelling of the current work system and usability assessm...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2009.07.002
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:There are very few studies reporting the impact of providing intravenous (IV) preparation information on quality use of antimicrobials, particularly regarding their reconstitution and dilution. Therefore, to improve these processes in IV antimicrobial administration, an IV preparation information system (IPI...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2016.07.005
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Autonomous use of online health care services without interaction with a health care provider challenges existing models for achieving informed consent (IC); current examinations of this issue have focused on commercial direct-to-consumer genetic testing. As IC is integral to publicly funded clinical testing...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2017.05.020
更新日期:2017-09-01 00:00:00
abstract:INTRODUCTION:This paper explores the benefits of using n-grams and semantic features for the classification of disease outbreak reports, in the context of the BioCaster disease outbreak report text mining system. A novel feature of this work is the use of a general purpose semantic tagger - the USAS tagger - to generat...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2009.03.010
更新日期:2009-12-01 00:00:00
abstract::An information revolution is underway which will have an impact on all sectors of society. It will fundamentally change national and international health systems. The global Internet is a key influence and will change the balance of power within and between healthcare professions, and between them and the general publ...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/s1386-5056(97)00106-8
更新日期:1998-02-01 00:00:00
abstract:INTRODUCTION:The rapid scale-up of HIV care and treatment in resource-limited countries requires concurrent, rapid development of health information systems to support quality service delivery. Mozambique, a country with an 11.5% prevalence of HIV, has developed nation-wide patient monitoring systems (PMS) with standar...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2016.11.002
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To apply cognitive task analyses of the Biomedical query mediation (BQM) processes for EHR data retrieval at multiple sites towards the development of a generic BQM process model. MATERIALS AND METHODS:We conducted semi-structured interviews with eleven data analysts from five academic institutions and one g...
journal_title:International journal of medical informatics
pub_type: 杂志文章
doi:10.1016/j.ijmedinf.2016.06.006
更新日期:2016-09-01 00:00:00