Abstract:
:Andexanet alfa, a reversing agent for anticoagulants that inhibit factor Xa, has recently been licensed in the United States. We discuss the impact of this licensure on current practice and review in detail the problems of a neglected and growing clinical area: reversing the anticoagulation effect of factor Xa inhibitors in bleeding trauma patients. We identify areas of practice that need research so that care of bleeding trauma patients receiving direct factor Xa inhibitors can be improved.
journal_name
Bloodjournal_title
Bloodauthors
Hunt BJ,Neal MD,Stensballe Jdoi
10.1182/blood-2018-06-850396subject
Has Abstractpub_date
2018-12-06 00:00:00pages
2441-2445issue
23eissn
0006-4971issn
1528-0020pii
blood-2018-06-850396journal_volume
132pub_type
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