Are molecular subgroups of medulloblastomas really prognostic?

abstract：PURPOSE OF REVIEW:To review the most relevant developments in the understanding of headache in idiopathic intracranial hypertension (IIH). RECENT FINDINGS:The phenotype of the typical IIH headache is diverging from the historical thinking of a raised intracranial pressure headache, with the majority being classified a...

journal_title：Current opinion in neurology

authors： Mollan SP,Hoffmann J,Sinclair AJ

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This article discusses recent advances in the understanding of clinical and genetic aspects of primary ataxias, including congenital, autosomal recessive, autosomal dominant, episodic, X-linked, and mitochondrial ataxias, as well as idiopathic degenerative and secondary ataxias. RECENT FINDINGS:Many ...

journal_title：Current opinion in neurology

authors： Teive HA,Ashizawa T

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Cerebral amyloid angiopathy (CAA) is diagnosed primarily as a cause of lobar intracerebral hemorrhages (ICH) in elderly patients. With improving MRI techniques, however, the role of CAA in causing other symptoms has become clear. Recognizing the full clinical spectrum of CAA is important for diagnosis...

journal_title：Current opinion in neurology

authors： Wermer MJH,Greenberg SM

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review considers the role of neuroimaging in developmental disorders by highlighting recent studies in two distinct, but overlapping, developmental disorders: autism and fragile X syndrome. RECENT FINDINGS:After a decade of conflicting results in neuroimaging studies of autism, recent studies ha...

journal_title：Current opinion in neurology

authors： Greicius MD

更新日期：2003-04-01 00:00:00

abstract：:Various functional imaging modalities can be applied in acute ischaemic stroke to identify functionally impaired, but morphologically preserved tissue (i.e. the penumbra), and to distinguish it from irreversibly damaged tissue. Flow thresholds for irreversible tissue destruction resulting in functional impairment, as ...

journal_title：Current opinion in neurology

authors： Heiss WD,Forsting M,Diener HC

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Drug resistance is an important clinical problem: it is associated with higher rates of somatic and psychiatric comorbidities and cognitive/memory decline, with seizures being just the 'tip of the iceberg'. This review summarizes recent developments in imaging research, focusing specifically on the fu...

journal_title：Current opinion in neurology

authors： Koepp MJ

更新日期：2014-04-01 00:00:00

abstract：:Nuclear magnetic resonance methods as a whole have contributed as much to the study and treatment of epilepsy as to any branch of medicine. The pace of the progress in this field increases as recently developed nuclear magnetic resonance techniques mature into practical tools for epilepsy research and management. Rece...

journal_title：Current opinion in neurology

authors： Prichard JW

更新日期：1997-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associated antigens, and to review several chronic epileptic disorders, including Rasmussen's encephalitis, f...

journal_title：Current opinion in neurology

authors： Spatola M,Dalmau J

更新日期：2017-06-01 00:00:00

abstract：:This article reviews recent studies concerning memory and language disorders in Alzheimer's disease and other neurodegenerative conditions. It shows how different memory and language subcomponents may differentially be impaired in different neurodegenerative diseases and at different stages of the same disease. ...

journal_title：Current opinion in neurology

authors： Dalla Barba G,Boller F

更新日期：1998-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Experimental and clinical studies have suggested that epileptic seizures can be modulated or interrupted by electrical stimulations of subcortical structures that may exert a remote control on seizure generators. The aim of this review is to present these recent reports and to address the perspectives...

journal_title：Current opinion in neurology

authors： Kahane P,Depaulis A

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The field of new technologies for upper-limb rehabilitation is exploding. The review presents new trends and studies of effectiveness from recent literature regarding robots, virtual reality and telerehabilitation for neurorehabilitation of the upper limb. RECENT FINDINGS:There appears to be a greate...

journal_title：Current opinion in neurology

authors： Brochard S,Robertson J,Médée B,Rémy-Néris O

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Converging evidence from animal models of stroke and clinical trials suggests that aerobic exercise has effects across multiple targets. RECENT FINDINGS:The subacute phase is characterized by a period of heightened neuroplasticity when aerobic exercise has the potential to optimize recovery. In anima...

journal_title：Current opinion in neurology

authors： Ploughman M,Kelly LP

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to systematically and critically review the relationship between migraine and estrogen, the predominant female sex hormone, with a focus on studies published in the last 18 months. RECENT FINDINGS:Recent functional MRI (fMRI) studies of the brain support the existence of anatomical and fun...

journal_title：Current opinion in neurology

authors： Chai NC,Peterlin BL,Calhoun AH

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an overview of recent developments in diagnosis, pathophysiology, neuroimaging and management of functional (psychogenic) movement disorders (FMD). RECENT FINDINGS:There has been increasing interest to study the underlying pathophysiology of FMD, which has resulted in a broadened...

journal_title：Current opinion in neurology

authors： Czarnecki K,Hallett M

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To give an overview on topics of pupillary function selected according to their relevance in clinical neurology. Mainly publications of the last 3 years have been considered. RECENT FINDINGS:The discovery of photosensitive retinal ganglion cells not serving vision, but serving circadian rhythm and th...

journal_title：Current opinion in neurology

authors： Wilhelm H

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the application of advanced MRI sequences such as magnetic resonance spectroscopy, diffusion tensor imaging and functional MRI for the evaluation of patients with altered consciousness. RECENT FINDINGS:Magnetic resonance spectroscopy, volumetry and diffusion tensor imaging have shown pro...

journal_title：Current opinion in neurology

authors： Galanaud D,Naccache L,Puybasset L

更新日期：2007-12-01 00:00:00

abstract：:Trauma to the developing brain constitutes an unexplored field. The few studies attempting to model and study paediatric head trauma, the leading cause of death and disability in the paediatric population, have revealed interesting aspects and potential targets for future research. One feature unique to the developing...

journal_title：Current opinion in neurology

authors： Felderhoff-Mueser U,Ikonomidou C

更新日期：2000-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will discuss aspects of cytokine networks in neuroinflammatory diseases and attempt to provide some explanation for our failures and successes in translating preclinical data to benefit patients with multiple sclerosis (MS). We will discuss innate cytokines such as tumor necrosis factor al...

journal_title：Current opinion in neurology

authors： Codarri L,Fontana A,Becher B

更新日期：2010-06-01 00:00:00

abstract：:Insight into the pathomechanisms of the benign positional vertigo syndromes has led to quick and effective treatment with positional manoeuvres. Our understanding of other causes of vertigo is progressing at a slower pace, but several recent findings regarding vestibular neuritis, vascular compression of the eighth ne...

journal_title：Current opinion in neurology

authors： Lempert T

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the most important issues a clinician must consider whenever selecting and administering antiepileptic drugs (AEDs). There is no available algorithm that identifies how to individualize selection of AEDs. Proper selection and administration can make an enormous difference in both effective...

journal_title：Current opinion in neurology

authors： Cheng JY,French JA

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Gadolinium-enhancement depicts blood-brain barrier disruption associated with new inflammatory MRI lesions in multiple sclerosis (MS) and is widely used for diagnosis and therapeutic monitoring. However, earlier and more specific markers of inflammation are urgently needed. RECENT FINDINGS:Susceptibi...

journal_title：Current opinion in neurology

authors： Hagens M,van Berckel B,Barkhof F

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In multiple sclerosis as the most common inflammatory demyelinating disease in Western countries, major therapeutic success has been achieved with regard to strategies targeting immunological master switches. These approaches effectively reduce inflammatory disease activity but fail to address ongoing...

journal_title：Current opinion in neurology

authors： Aktas O,Albrecht P,Hartung HP

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The relative influence of genes and environment on the liability to neurodevelopmental disorders (NDDs) can be investigated using a twin design. This review highlights the results of the most recent twin studies of NDDs. RECENT FINDINGS:Recent twin studies have confirmed that NDDs show moderate-to-hi...

journal_title：Current opinion in neurology

authors： Posthuma D,Polderman TJ

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to refer to recent arguments supporting the existence of specific propagation mechanisms associated with spreading of neuron injury in amyotrophic lateral sclerosis (ALS). RECENT FINDINGS:Misfolded ALS-linked protein accumulation can induce aggregation of their native equiva...

journal_title：Current opinion in neurology

authors： Pradat PF,Kabashi E,Desnuelle C

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Convergent evidence from a number of neuroscience disciplines supports the hypothesis that Alzheimer's disease and other neurodegenerative disorders progress along brain networks. This review considers the role of neuroimaging in strengthening the case for network-based neurodegeneration and elucidati...

journal_title：Current opinion in neurology

authors： Greicius MD,Kimmel DL

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the background, principles and implementation of the Stroke Action Plan for Europe 2018--2030 (SAP-E) in the perspective of the current COVID-19 pandemic. RECENT FINDINGS:SAP-E sets targets for the implementation of evidence-based preventive actions and stroke services to 2030. A recent m...

journal_title：Current opinion in neurology

authors： Christensen H,Pezzella FR,Action Plan for Stroke in Europe Implementation Steering Committee.

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Localization of focal epileptic brain is critical for successful epilepsy surgery and focal brain stimulation. Despite significant progress, roughly half of all patients undergoing focal surgical resection, and most patients receiving focal electrical stimulation, are not seizure free. There is intens...

journal_title：Current opinion in neurology

authors： Cimbalnik J,Kucewicz MT,Worrell G

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In recent years, advances in the understanding of the regulatory mechanisms of the immune system has led to the development of new approaches for cancer treatment. Currently, immune checkpoint inhibitors are the first successful examples of this approach and several agents that target cytotoxic lympho...

journal_title：Current opinion in neurology

authors： Hottinger AF

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:With the aging of the population, treatment of painful neuropathies is becoming more and more important for neurological practice. This short review highlights recent findings and current problems. RECENT FINDINGS:In addition to tricyclic antidepressants and gabapentin, the reliability of which is es...

journal_title：Current opinion in neurology

authors： Cruccu G

更新日期：2007-10-01 00:00:00

abstract：:Positron emission tomography, single photon emission computed tomography and magnetic resonance spectroscopy provide distinct, uncorrelated and sensitive indicators of brain tumors which can be used to improve differential diagnosis, biopsy guidance or therapy monitoring. New findings, including conflicting ethyl-cyst...

journal_title：Current opinion in neurology

authors： Slosman DO,Lazeyras F

更新日期：1996-12-01 00:00:00