Abstract:
:The thermophilic microorganism Bacillus caldolyticus was incubated in laboratory scale stirred bioreactors under pressurised conditions at different aeration rates. Increased amounts of CO2/bicarbonate were solubilised under the chosen conditions. A reduction in aeration rate from 1 vvm to 0.1 vvm resulted in accumulation of CO2 and bicarbonate up to 126 mg l(-1) and 733 mg l(-1), respectively and also increased secretion of α-amylase and neutral proteases (increases of 123% and 52%, respectively). In this paper, the effect of reduced aeration rate on CO2/bicarbonate concentration and enzyme activities is presented. The selected fermentation conditions are closely related to those prevalent in large scale bioreactors and may offer the possibility of achieving high enzyme yields at reduced aeration costs on an industrial scale.
journal_name
N Biotechnoljournal_title
New biotechnologyauthors
Popović MK,Senz M,Bader J,Skelac L,Schilf W,Bajpai Rdoi
10.1016/j.nbt.2013.10.007subject
Has Abstractpub_date
2014-03-25 00:00:00pages
141-9issue
2eissn
1871-6784issn
1876-4347pii
S1871-6784(13)00136-2journal_volume
31pub_type
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