Abstract：
:The paper provides a review of the literature on a relevant non-drug prevention problem, namely the negative effect of trans isomers of unsaturated fatty acids (trans-UFA) on the risk of circulatory system diseases (CSD) and other chronic noncommunicable diseases. It gives data on the specific features of the structure and ability of trans-UFA to elevate the plasma levels of atherogenic low-density lipoproteins and to lower those of non/antiatherogenic high-density lipoproteins. The natural sources of their moderate content in the animal fats from ruminants and those of their redundant content in the margarines manufactured by hydrogenation of liquid vegetable oils are described. A new technology for preparing soft margarines (spreads) is presented, which can produce fatty products that do not virtually contain trans-UFA. There is evidence that trans-UFA can considerably raise the risk of CSD and their acute complications. It is concluded that the manufacture of fatty products with low and even no trans-UFA levels should be expanded in Russia to improve its population's health.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Perova NV,Metel'skaia VA,Boĭtsov SAsubject
Has Abstractpub_date
2013-01-01 00:00:00pages
113-7issue
9eissn
0040-3660issn
2309-5342journal_volume
85pub_type
杂志文章,评审abstract：:Novel antihyperlipidemic micronized phenofibrate lipantil 200 M was tested for safety and efficacy (one 200 mg capsule a day for 3 months) in 27 patients having cholesterol level above 6.5 mmol/l. The effect emerged upon 1 month of administration and persisted till the end of the treatment. In combined hyperlipidemia ...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:30 untreated patients with membranoproliferative glomerulonephritis (MPGN) with isolated urinary syndrome were examined for cellular and humoral immunity. There was a significant (p < 0.05) reduction of the number of T-helpers/inductors (T4/4B4) and early undifferentiated lymphoid precursors with the marker enzyme. T-...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The hypotensive and diuretic properties of heparin were evaluated in 95 patients with different clinical and morphological varieties of chronic glomerulonephritis (CGN). The arterial blood pressure dropped in all the patients treated with heparin. The maximal effect was attained toward the end of heparin treatment (by...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：AIM:To study effects of ivabradin on clinicohemodynamic and prognostic parameters in patients after myocardial infarction (MI) with systolic chronic cardiac failure (SCCF). MATERIAL AND METHODS:A population-based randomized prospective trial enrolled 49 patients (40 males--81.6%, mean age 63.1 +/- 8.1 years) with sinu...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-01-01 00:00:00
abstract：:Forty patients and 14 donors were examined. Twenty-two patients were diagnosed to have congestive cardiomyopathy (CCM), and 18 to have non-rheumatic myocarditis. The total number of T and B lymphocytes and lymphocyte subpopulations were measured by the method of surface markers (T mu and T gamma) and concurrently with...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The paper is concerned with a clinical picture of various types of occupational allergic diseases caused by exposure to occupational allergens. In view of a clinical course and pathogenesis of these diseases a set of diagnostic methods was developed, including allergy-oriented examination of patients using skin, endon...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:The aim of the study is to study the state of the immunological and hormonal background in patients with non-hospital pneumonia (NP) - liquidators of the accident at the Chernobyl nuclear power plant (ChNPP) after treatment. MATERIALS AND METHODS:Patients with NP were divided into 2 groups of liquidators of the Ch...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2019.03.000115
更新日期：2019-03-30 00:00:00
abstract：AIM:To estimate the time course of changes in brachial artery (BA) functional parameters in patients with unstable angina (UA) treated with angiotensin-converting enzyme inhibitors. SUBJECTS AND METHODS:After examination, 30 patients with Braunwald Classes IB and IIB UA were randomized to two groups to receive perindo...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-01-01 00:00:00
abstract：AIM:To evaluate the anti-ischemic and anti-anginal efficacy of meldonium (Idrinol) in its short-term use as part of combination therapy in patients with chronic heart failure in the early post-infarction period. SUBJECTS AND METHODS:The investigation enrolled 60 patients (men and women) aged 45 to 75 years at weeks 3-...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-01-01 00:00:00
abstract：:Levels of R proteins (RP) and activity of lipid peroxidation (LPO) were measured in 209 patients with RA. It was noted that RP levels and LPO activity correlated with the activity of inflammation. A rapid RA progression was characterized by higher RP levels and LPO activity, while polyarthritis by more intensive RP me...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The status of the blood kinin system, activity of serum inhibitors of proteinases (alpha 1-protease inhibitor and alpha 2-macroglobulin) as well as indices of activity of trypsin-like proteinases, elastolytic and fibrinolytic activity, free antitryptic activity and complete content of acid stable inhibitors were studi...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The most effective treatment for pathological obesity is bariatric surgery; however, a patient may postoperatively develop vitamin deficiencies. In inadequate intake of food and its malabsorption after surgery, there are chiefly deficiencies of vitamins B1, B6, B12, and vitamin E, leading to complications as central a...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.17116/terarkh20158712117-121
更新日期：2015-01-01 00:00:00
abstract：:High-intensity impulse laser radiation proved effective in 23 patients with esophageal candidiasis. The highest effect was achieved in its use with nistatin. In low laser efficacy radiation should be combined with transendoscopic administration of granulocytes concentrate. This produced clinico-endoscopic remission in...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:To quantify interleukin-8 (IL-8), interleukin-2 (IL-2) and soluble receptor of IL-2 (sIL-2r) in blood serum of patients with various forms of ischemic heart disease (IHD). MATERIAL AND METHODS:Levels of IL-8, IL-2 and sIL-2r were measured with enzyme immunoassay (EIA) in the serum of 75 patients with IHD: angina o...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Toxic patterns of diphtheria of the fauces in adults are characterized by laryngeal lesions which considerably deteriorate the disease prognosis. The clinical manifestations of diphtheric croup may be unpronounced in such cases and be masked by other severe disease symptoms. If patients with toxic diphtheria develop c...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The paper describes a clinical case of celiac disease with grade 3 malabsorption, which is associated with recurrent aphthous stomatitis and schizophrenia. On readmission after 8 months of strict adherence to his gluten-free diet, the patient was observed to be in clinical remission and to have normalized laboratory i...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：AIM:To study prevalence of arterial hypertension (AH) in relation to gender, age, profession, risk factors (RF), RF combination; efficacy of active long-term multifactor prevention among the employees of industrial enterprises in some regions of Russia. MATERIAL AND METHODS:14000 males and 20969 females from industria...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,多中心研究
doi：
更新日期：2007-01-01 00:00:00
abstract：AIM:To investigate the impact of double filtration plasmapheresis (DFPP) and therapeutic plasma exchange (TPE) on hemostasis in renal transplant recipients. MATERIALS AND METHODS:54 renal transplant patients with an acute humoral rejection were treated with therapeutic apheresis methods: 24 patients with DFPP and 30 p...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh201890622-27
更新日期：2018-06-20 00:00:00
abstract：AIM:To try arthrotek, a combined drug, in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS:10 RA women aged 30 to 60 years with endoscopically verified minimal affection of gastroduodenal mucosa (not more than 25 hemorrhages and/or 5 erosions) received arthrotek (1 tablet 3 times a day for 3 months). The...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：AIM:To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF). MATERIAL AND METHODS:22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:There was No correlation between the state of immunological reactivity in patients with acute pneumonia and the nature of infiltration of the pulmonary tissue (focal, confluent). Indices characterizing the cellular and humoral immunity links, were, to a large extent, related to a course of disease (complicated, uncomp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Comparison of proband concordance of the phenotypic correlation coefficients according to the proneness to disease derived on analysis of the groups of mono- and dizygote twins born in 1930-1959 in the city of Yerevan presenting with chronic non-obstructive and chronic obstructive bronchitis revealed a substantial rol...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:In three patients with multiple myeloma, stage IIIA, a complete remission lasting from 6 to 8 years was attained, in spite of the fact that not all of them received treatment. In the latter case the remission lasted from 5 to 6 years. One of the patients had diffuse Gk + BIk myeloma, one presented with multiple focal ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The paper shows more than 40 years' experience with ursodeoxycholic acid (UDCA) used as a drug; during this period it has demonstrated its rather high clinical efficacy. Due to the range of its inherent pleiotropic (choleretic, cytoprotective, immunomodulatory, antiapoptotic, hypocholesterolemic, and litholytic) prope...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.17116/terarkh201587484-90
更新日期：2015-01-01 00:00:00
abstract：:The effect of i. v. verapamil administration on some indices of the hemodynamics of the greater and lesser circulation was studied in 19 patients with bronchial asthma by a multiple approach using noninvasive methods (rheopulmonography, polycardiography, tetrapolar chest rheography). A decrease in the systemic as well...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Altogether 29 patients (14 with a characteristic clinical picture of CHD, 6 with probable angina and 9 with nonischemic cardialgia) were investigated by methods of two-dimensional echocardiography (echoCG) at rest and in combination with isometric exercise and left atrial transesophageal pacing test (LATPT) as well as...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Blood plasma free radical lipid oxidation was studied in 98 patients with acute dysentery (AD) and 64 patients with food toxinfection (FTI). Free radical lipid oxidation was assessed by the intensity of chemiluminescence and the level of lipid peroxides. Activation of blood plasma lipid peroxidation was established wi...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:To assess efficacy of cyclopheron (Polysan production) as opisthorchiasis pretreatment in patients with chronic viral hepatitis C (CHC). MATERIAL AND METHODS:Fifteen CHC patients received cyclopheron by 6 month scheme before dehelminthization. The effect was evaluated by dynamics of clinical symptoms, results of f...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：AIM:To study the effectiveness of a fixed combination of perindopril and amlodipine, with the subsequent addition of indapamide-retard in male patients with arterial hypertension (AH), obesity and severe sleep apnea (OSAS). MATERIALS AND METHODS:The study included 43 male patients in whom antihypertensive therapy titr...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2018.12.000005
更新日期：2018-12-30 00:00:00
abstract：:The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A sta...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
