Placental and circulating pregnancy-associated plasma protein A concentrates in normal and pathological term pregnancies.

Abstract:

:The relationship between placental and peripheral concentrations of pregnancy-associated plasma protein A (PAPP-A) was investigated, using specific radioimmunoassay techniques. At term, placental concentrations of PAPP-A were significantly lower in diabetic pregnancies; 1.9 +/- 0.2 micrograms/mg (mean +/- SE) placental protein as compared with controls (3.2 +/- 0.3). Similar findings were noted when results were analyzed per total placental weight. Patients with classes C-R (1.2 +/- 0.3) had significantly lower PAPP-A levels than in classes A, B (2.4 +/- 0.3 micrograms/mg protein, P = .02). Peripheral PAPP-A levels were measured in patients with chronic hypertension, toxemia, diabetes mellitus, and healthy controls. Overall, the distribution of PAPP-A values in patients with diabetes mellitus were different from controls. In addition, concentrations of PAPP-A in patients with classes B-D were significantly lower than in class A (P less than .001). In patients with chronic hypertension, some values of PAPP-A were lower than the tenth percentile, while patients with toxemia had a distribution which was similar to that of controls.

journal_name

Obstet Gynecol

authors

Barnea ER,Bischoff P,Page C,DeCherney AH,Herrmann W,Naftolin F

doi

10.1097/00006250-198609000-00019

subject

Has Abstract

pub_date

1986-09-01 00:00:00

pages

382-6

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

68

pub_type

杂志文章
  • Nonsurgical management of pelvic organ prolapse.

    abstract::Although surgical management of symptomatic pelvic organ prolapse (POP) is common and often necessary, conservative treatments such as pessaries, pelvic floor muscle training, or both can usually result in symptomatic improvement. When treating patients with POP, health care practitioners should focus primarily on ide...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/AOG.0b013e31824c0806

    authors: Culligan PJ

    更新日期:2012-04-01 00:00:00

  • Fetal puncture during midtrimester amniocentesis.

    abstract::Four cases of fetal puncture during midtrimester amniocentesis are reported; in one instance the baby apparently sustained temporary neurologic damage. None of the lesions was detected at the initial neonatal examination. From our data and a review of the literature, we estimate that fetal puncture occurs in 1-3% of m...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Karp LE,Hayden PW

    更新日期:1977-01-01 00:00:00

  • Factors predisposing to and outcome of gestational diabetes.

    abstract::Two hundred thirteen women with abnormal glucose tolerance tests (GTTs) were diagnosed over 9 years by a screening program involving the total antenatal population. Each subject was matched for age, parity, and ethnic group with a control. The gestational diabetics were subdivided into classes A1 or A2 based on the fa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Maresh M,Beard RW,Bray CS,Elkeles RS,Wadsworth J

    更新日期:1989-09-01 00:00:00

  • Potential for bias in studies of the influence of human immunodeficiency virus infection on the recognition, incidence, clinical course, and microbiology of pelvic inflammatory disease.

    abstract::As the human immunodeficiency virus (HIV) epidemic affects more women, clinicians are increasingly observing pelvic inflammatory disease (PID) in HIV-infected women. The extent to which PID is a factor in the recognition of HIV or HIV is a factor in the recognition of PID is unknown. Even less is known about how HIV i...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Irwin KL,Rice RJ,Sperling RS,O'Sullivan MJ,Brodman M

    更新日期:1994-09-01 00:00:00

  • Three fetal ponderal indexes in normal pregnancy.

    abstract::The relationship of three different fetal ponderal indexes was studied in 116 normal pregnancies between 20 and 41 weeks. All three fetal ponderal indexes were found to be independent of gestational age. Throughout normal gestation, the femur length to abdominal circumference ratio X 100 was found to be 22.3 +/- 2.4 (...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Vintzileos AM,Neckles S,Campbell WA,Andreoli JW Jr,Kaplan BM,Nochimson DJ

    更新日期:1985-06-01 00:00:00

  • Leuprolide acetate in the management of ureteral obstruction caused by endometriosis.

    abstract::Endometriotic ureteral obstruction is a serious event commonly diagnosed late and therefore associated with a major risk of hydronephrotic renal atrophy. The standard therapy is surgical. However, medical treatment has been reported using danazol, progestins, and estrogen-progestin combinations, although solid documen...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rivlin ME,Miller JD,Krueger RP,Patel RB,Bower JD

    更新日期:1990-03-01 00:00:00

  • Ultrasonic assessment of fetal response to second-trimester amniocentesis.

    abstract::Twenty-three patients undergoing second-trimester amniocentesis were ultrasonically monitored for 30 minutes before and 30 minutes after the amniocentesis. Fetal movements were recorded as movements of limbs, trunk, or combined limb-trunk movements. Fetal heart rates were determined at ten-minute intervals before and ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Gianopoulos J,Elias SS,Simpson JL,Tamura R

    更新日期:1986-03-01 00:00:00

  • Development of a computerized telecommunication system for in-training evaluation of residents in a laparoscopic educational program.

    abstract:OBJECTIVE:To describe our initial experience with a computerized telecommunication system, termed the interactive voice-response system, to record resident performance of laparoscopic surgery. METHODS:After completing a laparoscopic procedure, the surgeon and resident telephone a toll-free number independently and res...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/S0029-7844(97)00137-3

    authors: Fung Kee Fung MP,Parboosingh IJ,Temple LM,Guy d'Anjou C,Haebe J,Lussier R

    更新日期:1997-07-01 00:00:00

  • Body mass index and outcome of incontinence surgery.

    abstract:OBJECTIVE:To analyze the influence of body mass on the outcome of surgery for urinary incontinence. METHODS:Among 291 women operated on for stress incontinence, 187 (64%) were available for follow-up at 5 years. Eighty women had anterior colporrhaphy, 49 anterior colporrhaphy with needle suspension of the bladder neck...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00513-4

    authors: Zivkovic F,Tamussino K,Pieber D,Haas J

    更新日期:1999-05-01 00:00:00

  • Transobturator sling compared with single-incision mini-sling for the treatment of stress urinary incontinence: a randomized controlled trial.

    abstract:OBJECTIVE:To determine the efficacy and safety of a single-incision mini-sling compared with a transobturator midurethral sling for stress urinary incontinence (SUI) treatment. METHODS:This prospective single-center randomized controlled trial involved 130 women with a diagnosis of SUI. Primary outcomes were the objec...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0000000000000148

    authors: Djehdian LM,Araujo MP,Takano CC,Del-Roy CA,Sartori MGF,Girão MJBC,Castro RA

    更新日期:2014-03-01 00:00:00

  • Improved outcome of preterm infants when delivered in tertiary care centers.

    abstract:OBJECTIVE:Previous studies that compared outcomes of infants born outside tertiary care centers (outborn) with those born in tertiary care centers (inborn) did not account for admission illness severity and perinatal risks. The objective of this study was to examine whether outborn status is associated with higher mort...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(01)01438-7

    authors: Chien LY,Whyte R,Aziz K,Thiessen P,Matthew D,Lee SK,Canadian Neonatal Network.

    更新日期:2001-08-01 00:00:00

  • Reliability of intrauterine pressure measurements.

    abstract::The reliability of intrauterine pressure measurements was studied by placing two catheters in the same uterus in women in labor. Nineteen parturients were studied, five with two Intran I catheters in different pockets of amniotic fluid, five with two Intran II catheters in different pockets, and nine with two Intran I...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Arulkumaran S,Yang M,Tien CY,Ratnam SS

    更新日期:1991-11-01 00:00:00

  • Second-Trimester Fetal Loss in a Patient With Hyperemesis Gravidarum Complicated by Refeeding Syndrome.

    abstract:BACKGROUND:Refeeding syndrome is a rare constellation of electrolyte abnormalities after reintroduction of glucose during an adaptive state of starvation and malnutrition, resulting in fluid shifts, end-organ damage, and, potentially, death. We present a case of fetal death in a patient with hyperemesis gravidarum comp...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003276

    authors: Mayer KH,McGill AL

    更新日期:2019-06-01 00:00:00

  • Timing of the postpartum Papanicolaou smear.

    abstract:OBJECTIVE:To study the relation between the timing of the postpartum examination and the postpartum Papanicolaou smear. METHODS:One hundred eighty-four women in labor at Arlington Community Hospital were randomized to receive their postpartum Papanicolaou smear at 4, 6, or 8 weeks after delivery. Samples from the exoc...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rarick TL,Tchabo JG

    更新日期:1994-05-01 00:00:00

  • Prenatal prediction of lethal pulmonary hypoplasia using ultrasonic fetal chest circumference.

    abstract::Ultrasonic measurement of fetal chest circumference was tested as a predictor of pulmonary hypoplasia in a group of 26 fetuses at known risk. A 42% prevalence of autopsy-proved pulmonary hypoplasia was found in this population. Chest circumference measurements were plotted on published nomograms based upon head circum...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Songster GS,Gray DL,Crane JP

    更新日期:1989-02-01 00:00:00

  • The relationship of one abnormal glucose tolerance test value and pregnancy complications.

    abstract::While an abnormal oral glucose tolerance test (GTT) is known to be associated with an increased risk of pregnancy complications, the impact of one abnormal value is not clear. In 1986 we screened 4618 pregnant women for gestational diabetes at 24-28 weeks' gestation. Eighty-seven percent had normal results; of the 13%...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lindsay MK,Graves W,Klein L

    更新日期:1989-01-01 00:00:00

  • Mesonephroid carcinoma of the ovary. A clinicopathologic, histochemical, and electron microscopic study.

    abstract::Eighteen patients with mesonephroid ovarian carcinoma were investigated. Typical findings for the mesonephroid tumors were abundant extracellular an some intracellular neutral mucin mixed with sulfate and carboxyl groups, and large amounts of glycogen, especially in clear cells. The latter observation is considered to...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Klemi PJ,Grönroos M

    更新日期:1979-04-01 00:00:00

  • Antihypertensive therapy and central hemodynamics in women with hypertensive disorders in pregnancy.

    abstract:OBJECTIVE:To estimate the changes in central hemodynamics features of pregnant women presenting with hypertensive disorders and to analyze the effects of standard antihypertensive treatment on maternal central hemodynamics. METHODS:Applanation tonometry was used to record the radial artery pulse waveform in 80 women p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318197c392

    authors: Khalil A,Jauniaux E,Harrington K

    更新日期:2009-03-01 00:00:00

  • Misoprostol compared with laminaria before early second-trimester surgical abortion: a randomized trial.

    abstract:OBJECTIVE:To compare the efficacy and acceptability of same-day misoprostol and overnight laminaria for cervical ripening before early second-trimester surgical abortion. METHODS:We performed a randomized, double-blinded, controlled trial comparing 400 microg of vaginal misoprostol, given 3-4 hours preoperatively, wit...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000168629.17326.00

    authors: Goldberg AB,Drey EA,Whitaker AK,Kang MS,Meckstroth KR,Darney PD

    更新日期:2005-08-01 00:00:00

  • Intrauterine aspiration of a large fetal ovarian cyst.

    abstract::Most large series of neonatal ovarian cysts are limited to those diagnosed in the newborn period. Eight cases of fetal ovarian cysts diagnosed prenatally by ultrasound have been reported, only one of which was aspirated in utero. Reported is the youngest fetus to undergo in utero aspiration of an ovarian cyst to reduc...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Landrum B,Ogburn PL Jr,Feinberg S,Bendel R,Ferrara B,Johnson DE,Thompson TR

    更新日期:1986-09-01 00:00:00

  • Perioperative antibiotic prophylaxis is cesarean section.

    abstract::The effect of an 8-hour, 3-dose perioperative regimen of cefazolin or placebo was evaluated in 97 patients. Postoperative morbidity occurred in 13 patients (27.1%) in the cefazolin group and in 17 patients (34.7%) who received placebo. The clinical sites of infection were similar in both groups except that wound infec...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Kreutner AK,del Bene VE,Delamar D,Huguley V,Harmon PM,Mitchell KS

    更新日期:1978-09-01 00:00:00

  • Treatment of ectopic pregnancy by transvaginal intratubal methotrexate administration.

    abstract::Twelve women with tubal pregnancies were treated with intratubal transvaginal methotrexate injection (1 mg/kg body weight). Serum beta-hCG levels decreased in all patients, and the resolution time from injection to undetectable beta-hCG levels was 14-120 days. In spite of declining serum beta-hCG and unruptured tubal ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Tulandi T,Bret PM,Atri M,Senterman M

    更新日期:1991-04-01 00:00:00

  • Effect of human immunodeficiency virus treatment on maternal mortality at a tertiary center in South Africa: a 5-year audit.

    abstract:OBJECTIVE:To review facility-based maternal deaths at a tertiary-level center in Johannesburg, South Africa, during a 5-year period (2003 to 2007) and to investigate the proportion of deaths attributable to human immunodeficiency virus (HIV), the etiology of deaths, and the effects of antiretroviral treatment introduce...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181af33e6

    authors: Black V,Brooke S,Chersich MF

    更新日期:2009-08-01 00:00:00

  • Prognostic factors associated with recurrence in clinical stage I adenocarcinoma of the endometrium.

    abstract::Two hundred sixty-four consecutive patients with clinical stage I endometrial adenocarcinoma who underwent primary surgical therapy between July 1979 and August 1988 were followed prospectively and evaluated for disease recurrence for 8-112 months (mean 51.5). Thirty-three patients (12.5%) developed recurrence or died...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lurain JR,Rice BL,Rademaker AW,Poggensee LE,Schink JC,Miller DS

    更新日期:1991-07-01 00:00:00

  • Barriers to Evidence-Based Transgender Care: Knowledge Gaps in Gender-Affirming Hysterectomy and Oophorectomy.

    abstract::Reversal of gender-discriminatory insurance coverage policies has led to a substantial increase in access to gender-affirming surgical care in the United States over the past 20 years. Although the evidence supports the safety, feasibility, and medical necessity of gender-affirming hysterectomy and oophorectomy, there...

    journal_title:Obstetrics and gynecology

    pub_type: 社论

    doi:10.1097/AOG.0000000000003472

    authors: Reilly ZP,Fruhauf TF,Martin SJ

    更新日期:2019-10-01 00:00:00

  • Successful spontaneous vaginal delivery during mechanical ventilatory support for the adult respiratory distress syndrome.

    abstract::The adult respiratory distress syndrome is a common cause of acute hypoxemic respiratory failure in the adult that is associated with a high mortality. There is a limited experience with managing this entity in the gravid patient. A case of successful management of mother and fetus through spontaneous delivery is pres...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sosin D,Krasnow J,Moawad A,Hall JB

    更新日期:1986-09-01 00:00:00

  • Use of a high-frequency aspiration-biopsy transducer for direct ultrasound-guided amniocentesis.

    abstract::The techniques and applications of amniocentesis performed with a new high-frequency aspiration-biopsy transducer are described in detail. The advantages of this technique are greatest in third-trimester patients where active fetal motion and diminished amniotic fluid volumes make unguided punctures difficult or impos...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Bree RL

    更新日期:1979-04-01 00:00:00

  • Intravenous ferric carboxymaltose compared with oral iron in the treatment of postpartum anemia: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate efficacy of rapid, large-dose intravenous (IV) administration of ferric carboxymaltose compared with oral iron therapy in anemic postpartum women. METHODS:In a randomized, controlled trial, we assigned anemic women (hemoglobin [Hb] less than or equal to 10 g/dL) within 10 days postpartum to recei...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.AOG.0000275286.03283.18

    authors: Van Wyck DB,Martens MG,Seid MH,Baker JB,Mangione A

    更新日期:2007-08-01 00:00:00

  • Integrated external and interstitial radiation therapy for primary carcinoma of the vagina.

    abstract::Twenty-seven patients with the diagnosis of primary carcinoma of the vagina were treated by definitive radiotherapy. Twenty-three patients received a combination of external and interstitial iridium-192 implant irradiation and four patients received only interstitial irradiation. Twenty-one patients had squamous cell ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198309000-00021

    authors: Puthawala A,Syed AM,Nalick R,McNamara C,DiSaia PJ

    更新日期:1983-09-01 00:00:00

  • The historic significance of circumcision.

    abstract::Understanding the importance of circumcision in the religious history of Western civilization provides an insight into why the surgical procedure is still so prevalent today. Circumcision appears as a motif in the religious literature of Western civilization throughout the ages. The history of the Jewish faith can be ...

    journal_title:Obstetrics and gynecology

    pub_type: 历史文章,杂志文章

    doi:10.1097/00006250-197804000-00023

    authors: Waszak SJ

    更新日期:1978-04-01 00:00:00