Abstract：
INTRODUCTION AND OBJECTIVES:There is no high-level evidence as to which primary treatment provides an overall survival (OS) or cancer-specific survival (CSS) advantage in high-risk localised prostate cancer (HRLPC). Our aim was to analyse the differences in survival and predictive factors in this group of patients, according to their primary treatment (radical prostatectomy (RP) or radiotherapy and androgen blockade (RT+HT)). MATERIAL AND METHODS:A retrospective study of 286 HRLPC patients diagnosed between 1996-2008, treated by RP (n=145) or RT+HT(n=141). Survival was assessed using the Kaplan-Meier method. Significant differences between the different variables were analysed using the log-rank test. A uni and multivariate Cox regression analysis was performed to identify risk factors. RESULTS:the median follow-up was 117.5 (IQR 87-158) months. The OS was longer (p=.04) in the RP patients, while there were no differences (P=.44) in CSS between either group. The type of primary treatment was not related to OS or CSS. Age (P=.002), the onset during follow-up of a 2nd tumour (P=.0001), and stage cT3a (P=.009) behaved as independent predictive variables of OS. None of the variables behaved as an independent predictive variable of CSS, although biochemical recurrence after rescue treatment (P=.058), and the onset of a 2nd tumour during follow-up showed a significant trend to statistical significance, the latter reducing specific cancer mortality (HR .16, 95%CI .02-1.18, P=.07). CONCLUSIONS:Primary treatment did not relate to OS or CSS in patients with HRPC.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Caño-Velasco J,Herranz-Amo F,Barbas-Bernardos G,Polanco-Pujol L,Hernández-Cavieres J,Lledó-García E,Hernández-Fernández Cdoi
10.1016/j.acuro.2018.06.006subject
Has Abstractpub_date
2019-03-01 00:00:00pages
91-98issue
2eissn
0210-4806issn
1699-7980pii
S0210-4806(18)30156-6journal_volume
43pub_type
杂志文章abstract：:The most common etiology of lymphedema in our environment is tumoral and, generally, it is due to treatment of the cancer itself. However, the initial presentation of prostate carcinoma as lymphedema is very rare. In fact, there aren't very few documented cases in literature. We described the case of a patient who was...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(07)73637-9
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abstract：:From the Second World War onwards an amazing development in science and clinical & surgery practice has taken place: antibiotics, blood storage, cardiac surgery, organ and tissue transplant, complete joint replacement, total intravenous nutrition or minimally invasive surgery. Paradoxically, during the last two decade...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(08)73792-6
更新日期：2008-01-01 00:00:00
abstract：:Presentation of 3 patients (aged 11 years, 9 months and 9 years old) with diaphragm-like valves in the anterior urethra. Haematuria, urinary tract infection and thin voiding stream were the most common symptoms. Transurethral endoscopic resection with cold blade solved the problem appropriately in two cases, though th...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：INTRODUCTION:Urinary incontinence (UI) is a complication of radical prostatectomy (RP) and transurethral resection of the prostate (TURP). The gold-standard treatment is the artificial urinary sphincter, however, new treatments have been investigated. OBJECTIVE:To examine the outcome of an adjustable transobturator ma...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2017.07.011
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:The increasing number of ultrasonographically detected asymptomatic, renal dilations have caused a lot of explorations to be performed in these patients. The Society of Fetal Urology proposed a four grades classification of echographic renal dilations and renographic studies are recommended in grades II to IV. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(01)72568-5
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abstract：CONTEXT:Despite being a validated source of biomarkers, liquid biopsy has not yet succeeded in becoming part of the standard clinical practice in prostate cancer patients. Few biomarkers undergo adequate validation, prospective and independent, of their predictive and/or prognostic value, which results in a lack of the...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2019.08.007
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abstract：:The stimulation of renal innervation activates vasoconstrictor mechanisms that compromise the parenchyma. In order to know the intensity and duration of these effects continuous electric stimulation was applied to the greater splanchnic nerve in 14 dogs for half an hour, completing both a pre and post monitoring of eq...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Severe vesicouretheral reflux sometimes causes terminal renal failure which then requires renal transplantation. In these patients it may be necessary to perform bilateral nephrectomy when associated to serious hypertension or urinary infections with a significant clinical impact. This paper presents the clinical pict...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(09)74165-8
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abstract：INTRODUCTION:Urinary calculi is an uncommon complication in kidney transplantation; several stone risk factors are found in transplanted patients, but in most cases there is not a relationship between these risk factors and stone formation. The treatment of these patients is complex due to their both immunosuppressive ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
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abstract：OBJECTIVE:To know the prevalence of the bilateral germ cell tumours of testis diagnosed in our Department and to review the literature. MATERIAL AND METHODS:64 patients diagnosed of a germ cell tumour of the testis were followed during an average period of 51.4 months (1-168 months). RESULTS:5 (7.8%) patients develop...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(00)72516-2
更新日期：2000-09-01 00:00:00
abstract：:The use of serum prostate-specific antigen screening to facilitate early detection of prostate cancer has resulted in a dramatic increase in the number of prostate needle core biopsies which pathologists must examine. This has been accompanied by a strong increase in the number of biopsies with ambiguous lesions, and ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73764-6
更新日期：2007-10-01 00:00:00
abstract：:We report a case of a carcinoid tumor originated in testicle associated with mature teratoma in a 31 years old male. Primary gonadal location of this tumor is unusual, moreover when associated with teratoma. Early diagnosis and treatment determine the prognostic of the patients affected of this neoplasm since the only...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73863-4
更新日期：2008-04-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2016.06.007
更新日期：2017-03-01 00:00:00
abstract：:Anatomical and physiological changes in the urinary tract develop during pregnancy. These changes may affect the urinary outflow. Urinary symptoms may develop during pregnancy in previously asymptomatic patients. Most of these symptoms will vanish after delivery. Some of them remain and others will become worse in con...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(99)72367-3
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73355-6
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2018.06.001
更新日期：2018-10-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2018.12.001
更新日期：2019-01-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73246-0
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-07-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2010.11.009
更新日期：2011-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/s0210-4806(01)72692-7
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(02)72815-5
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVES:To create a relational database for monitoring lithiasic patients. We describe the architectural details and the initial results of the statistical analysis. METHODS AND MATERIALS:Microsoft Access 2002 was used as template. Four different tables were constructed to gather demographic data (table 1), clinica...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：CONTEXT:The purpose of this article is to review the history of robotic surgery, its impact on teaching as well as a description of historical and current robots used in the medical arena. SUMMARY OF EVIDENCE:Although the history of robots dates back to 2000 years or more, the last two decades have seen an outstanding...
journal_title：Actas urologicas espanolas
pub_type： 历史文章,杂志文章
doi：10.1016/j.acuro.2011.04.005
更新日期：2011-10-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(06)73422-2
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74180-4
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION:Delayed graft function alter living donor transplantation is a subject of debate. Delayed graft function can be partially explained by renal ischemia-reperfusion injury, when severe is associated with decreased graft survival. In this experimental living donor model study, we analyze the hemodynamic, histo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(08)73802-6
更新日期：2008-01-01 00:00:00
abstract：:Presentation of one case of hyporreflexic bladder like a first step of neurotoxicity due to Vinca alkaloids. These drugs produces peripheral neuropathies as usual, but in some rare occasions they may affect to the autonomic nervous system with its effects in the bladder producing hyporreflexic. This disease reverts sp...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72447-8
更新日期：2000-03-01 00:00:00
