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Trends in documented co-occurring conditions in children with autism spectrum disorder, 2002-2010.

Abstract：

BACKGROUND:Autism spectrumdisorder (ASD) commonly presents with co-occurring medical conditions (CoCs). Little is known about patterns in CoCs in a time of rising ASD prevalence. AIMS:To describe trends in number and type of documented CoCs in 8-year-old children with ASD. METHODS:We used Autism and Developmental Disabilities Monitoring Network (ADDM) data, a multi-source active surveillance system monitoring ASD prevalence among 8-year-old children across the US. Data from surveillance years 2002, 2006, 2008, and 2010 were used to describe trends in count, categories, and individual CoCs. RESULTS:Mean number of CoCs increased from 0.94 CoCs in 2002 to 1.06 CoCs in 2010 (p < 0.001). The percentage of children with ASD with any CoC increased from 44.5% to 56.4% (p < 0.001). CoCs with the greatest increases were in general developmental disability (10.4% to 14.5%), language disorder (18.9% to 23.6%), and motor developmental disability (10.5% to 15.6%). Sex modified the relationship between developmental (P = 0.02) and psychiatric (P < 0.001) CoCs and surveillance year. Race/ethnicity modified the relationship between neurological conditions (P = 0.04) and surveillance year. CONCLUSIONS:The increase in the percentage of children with ASD and CoCs may suggest the ASD phenotype has changed over time or clinicians are more likely to diagnose CoCs.

journal_name

Res Dev Disabil

journal_title

Research in developmental disabilities

authors

Rubenstein E,Schieve L,Wiggins L,Rice C,Van Naarden Braun K,Christensen D,Durkin M,Daniels J,Lee LC

doi

10.1016/j.ridd.2018.08.015

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

168-178

eissn

0891-4222

issn

1873-3379

pii

S0891-4222(18)30197-5

journal_volume

83

pub_type

杂志文章

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