Abstract:
BACKGROUND:Nodular thyroid disease possesses the potential to harbor malignancy. Our aim was to evaluate the significance of cervical diffusion-weighted magnetic resonance imaging (DW-MRI) for the detection of malignant thyroid nodules. METHODS:Sixty-five thyroid nodules from 58 patients who had undergone surgery were evaluated. Preoperative parameters, demographic data, ultrasound findings, fine-needle aspiration biopsy results and apparent diffusion coefficient (ADC) values of the nodules at DW-MRI were compared with the results from postoperative pathology examinations. RESULTS:The "benign group" included 50 (76.9%) nodules, while 15 (23.1%) nodules constituted the "malignancy group". Minimum, maximum and mean ADC values of the nodules were significantly lower in the malignancy group (p < 0.05). The best cutoff value for the mean ADC value was 1.33 × 10-3 mm2/s, with a sensitivity of 66.67%, a specifity of 89.13%, a positive predictive value of 53.63% and a negative predictive value of 89.13%. A mean ADC value equal to or lower than 1.33 × 10-3 mm2/s was associated with 9 times higher risk of malignancy (odds ratio: 9.111, 95% confidence interval: 2.49-33.21). CONCLUSIONS:The ADC value detected by cervical DW-MRI can be considered a predictive parameter for the detection of thyroid cancer.
journal_name
Cir Espjournal_title
Cirugia espanolaauthors
Ekinci O,Boluk SE,Eren T,Ozemir IA,Boluk S,Salmaslioglu A,Leblebici M,Alimoglu Odoi
10.1016/j.ciresp.2018.04.016subject
Has Abstractpub_date
2018-12-01 00:00:00pages
620-626issue
10eissn
0009-739Xissn
1578-147Xpii
S0009-739X(18)30199-4journal_volume
96pub_type
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