Laparoscopic splenectomy for hereditary spherocytosis. A case series and review of the literature.

Abstract:

:Hereditary spherocytosis (HS) is a common inherited hemolytic anemia caused by a defective erythrocyte cellular membrane. Irrespective of type of surgery performed, several case reports comparing the two type of procedures, have not proven any significant difference between serum bilirubin, serum hemoglobin, red blood cells' and platelets' count, in the followup period at 6 and 12 months respectively, even if platelet count has maintained high for the first 6 months postoperatively, justifying an oral antiplatelet therapy for this time interval. In the present work, we present the use of LS as the treatment of choice for HS as a case series, with all the characteristics. KEY WORDS:Hereditary Spherocytosis, Laparoscopic Splenectomy. :La sferocitosi ereditaria (HS) è una anemia emolitica ereditaria in relazione alla presenza di una membrana eritrocitaria difettosa. Indipendentemente dal tipo di chirurgia adottata, numerose esperienze riportate il letteratura paragonando le due tecniche - splenectomia totale o parziale – non hanno dimostrato differenze significative tra tassi di bilirubinemia, emoglobinemia, conta eritrocitaria e piastrinica nel periodo postoperatorio a 6 e 12 mesi rispettivamente, anche se la conta delle piastrine si è mantenuta elevata nei primi 6 mesi postoperatori, giustificando un trattamento orale antipiastrinico per tutto questo periodo. In questo studio viene presentata una serie di splenectomie laparoscopiche quale trattamento di scelta, con tutti I dati relativi.

journal_name

Ann Ital Chir

authors

Zaharie F,Muresan MS,Tomuleasa C,Popa G,Blag C,Zaharie R,Zdrehus C,Dragomir M,Bumbea H,Irimie A,Dima D

subject

Has Abstract

pub_date

2018-07-11 00:00:00

eissn

0003-469X

issn

2239-253X

pii

S0003469X18028701

journal_volume

7

pub_type

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