Summary of linezolid activity and resistance mechanisms detected during the 2012 LEADER surveillance program for the United States.

Abstract:

:This study summarizes the linezolid susceptibility testing results for 7,429 Gram-positive pathogens from 60 U.S. sites collected during the 2012 sampling year for the LEADER Program. Linezolid showed potent activity when tested against 2,980 Staphylococcus aureus isolates, inhibiting all but 3 at ≤2 μg/ml. Similarly, linezolid showed coverage against 99.5% of enterococci, as well as for all streptococci tested. These results confirm a long record of linezolid activity against U.S. Gram-positive isolates since regulatory approval in 2000.

authors

Mendes RE,Flamm RK,Hogan PA,Ross JE,Jones RN

doi

10.1128/AAC.02112-13

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

1243-7

issue

2

eissn

0066-4804

issn

1098-6596

pii

AAC.02112-13

journal_volume

58

pub_type

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