Antibacterial chromene and chromane stilbenoids from Hymenocardia acida.

Abstract:

:Six chromene stilbenoids and one chromane stilbenoid were isolated from the African tree Hymenocardia acida. Several were moderately active against methicillin-resistant Staphylococcus aureus clinical isolate MRSA-108, including hymenocardichromanic acid, which was active at 8 μg/ml. None had IC50 values <20 μM in antiproliferation assays against several human cancer cell lines.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Starks CM,Williams RB,Norman VL,Rice SM,O'Neil-Johnson M,Lawrence JA,Eldridge GR

doi

10.1016/j.phytochem.2013.11.012

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

216-22

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(13)00447-0

journal_volume

98

pub_type

杂志文章
  • Phosphorylation-mediated regulation of a rice ABA responsive element binding factor.

    abstract::OREB1 is a rice ABRE binding factor characterized by the presence of multiple highly-conserved phosphorylation domains (C1, C2, C3, and C4) and two kinase recognition motifs, RXXS/T and S/TXXE/D, within different functional domains. An in vitro kinase assay showed that OREB1 is phosphorylated not only by the SnRK2 kin...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2010.10.005

    authors: Hong JY,Chae MJ,Lee IS,Lee YN,Nam MH,Kim DY,Byun MO,Yoon IS

    更新日期:2011-01-01 00:00:00

  • The biosynthesis of monolignols: a "metabolic grid", or independent pathways to guaiacyl and syringyl units?

    abstract::Lignin is a complex polymer formed by the oxidative polymerization of hydroxycinnamyl alcohol derivatives termed monolignols. The major monolignols in dicotyledonous angiosperm lignin are monomethylated guaiacyl (G) units derived from coniferyl alcohol, and dimethylated syringyl (S) units derived from sinapyl alcohol....

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9422(01)00092-9

    authors: Dixon RA,Chen F,Guo D,Parvathi K

    更新日期:2001-08-01 00:00:00

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale.

    abstract::A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)97091-2

    authors: Noorwala M,Mohammad FV,Ahmad VU,Sener B

    更新日期:1994-05-01 00:00:00

  • Identification of phytochelatin-related peptides in maize seedlings exposed to cadmium and obtained enzymatically in vitro.

    abstract::An analytical strategy based on the sensitivity of electrospray tandem mass spectrometry following a simplified and reproducible sample preparation procedure was evaluated for the determination of Cd-induced phytochelatins (PC) and related peptides in four maize varieties. In addition to the three known families of PC...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00489-1

    authors: Chassaigne H,Vacchina V,Kutchan TM,Zenk MH

    更新日期:2001-04-01 00:00:00

  • Bromoallenic lipid compounds from lichens of central Asia.

    abstract::The composition of two bromoallenic aliphatic fatty acids obtained from lichens collected around Lake Issyk-Kul (central Asia) is described. These compounds were identified by means of 1H and 13C NMR, MS and IR spectra. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00469-6

    authors: Rezanka T,Dembitsky VM

    更新日期:2001-04-01 00:00:00

  • Sinapoyltransferases in the light of molecular evolution.

    abstract::Acylation is a prevalent chemical modification that to a significant extent accounts for the tremendous diversity of plant metabolites. To catalyze acyl transfer reactions, higher plants have evolved acyltransferases that accept beta-acetal esters, typically 1-O-glucose esters, as an alternative to the ubiquitously oc...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2009.07.023

    authors: Stehle F,Brandt W,Stubbs MT,Milkowski C,Strack D

    更新日期:2009-10-01 00:00:00

  • Steroidal saponins from the leaves of Beaucarnea recurvata.

    abstract::Thirteen steroidal saponins were isolated from the leaves of Beaucarnea recurvata Lem. Their structures were established using one- and two-dimensional NMR spectroscopy and mass spectrometry. Six of them were identified as: 26-O-β-D-glucopyranosyl (25S)-furosta-5,20(22)-diene 1β,3β,26-triol 1-O-α-L-rhamnopyranosyl-(1→...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.03.004

    authors: Eskander J,Lavaud C,Harakat D

    更新日期:2011-06-01 00:00:00

  • Occurrence and biological significance of proanthocyanidins in the American diet.

    abstract::Dietary intake of proanthocyanidins (PAs) has been largely unknown because of the lack of reliable values for their content in foods. Recent development of an analytical method for PAs has allowed the quantification of individual oligomers and polymers. This method has been employed to analyze food samples collected u...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2005.03.025

    authors: Prior RL,Gu L

    更新日期:2005-09-01 00:00:00

  • Minor C-geranylated flavanones from Paulownia tomentosa fruits with MRSA antibacterial activity.

    abstract::Exhaustive chromatographic separation of the chloroform portion of the ethanolic extract obtained from Paulownia tomentosa (Thunb). Steud. (Paulowniaceae) fruits has led to isolation of ten C-6 geranylated flavanones tomentodiplacone C-I and mimulone C-E, featured by 3'-methoxy and 4'-hydroxy or 4'-hydroxy substitutio...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.01.002

    authors: Navrátilová A,Schneiderová K,Veselá D,Hanáková Z,Fontana A,Dall'Acqua S,Cvačka J,Innocenti G,Novotná J,Urbanová M,Pelletier J,Čížek A,Žemličková H,Šmejkal K

    更新日期:2013-05-01 00:00:00

  • Aristololactams and aporphines from the stems of Fissistigma oldhamii (Annonaceae).

    abstract::Two aristololactams, aristololactam GI (1) and aristololactam GII (2), and three aporphines, fissistigamide A (3), fissistigamide B (4) and fissistigmine (5), together with nineteen known alkaloids, one flavone and one anthraquinone were isolated from the ethanol extracts of the stems of Fissistigma oldhamii (Annonace...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.09.011

    authors: Ge YW,Zhu S,Shang MY,Zang XY,Wang X,Bai YJ,Li L,Komatsu K,Cai SQ

    更新日期:2013-02-01 00:00:00

  • Seco diterpenoids from Excoecaria agallocha L.

    abstract::Chemical examination of the ethyl acetate solubles of the CH(3)OH:CH(2)Cl(2) (1:1) extract of the roots of Excoecaria agallocha L. collected from Godavary estuary resulted in the isolation of three more new diterpenoids, agallochins M-O (1-3). The structures of the new diterpenoids were elucidated by a study of their ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00269-8

    authors: Anjaneyulu AS,Rao VL

    更新日期:2003-02-01 00:00:00

  • Tetrahydroisoquinoline-monoterpene glycosides from Cephaelis acuminata.

    abstract::From the dried roots of Cephaelis acuminata, five tetrahydroisoquinoline-monoterpene glycosides, 2-O-beta-D-glucopyranosyldemethylalangiside, demethylisoalangiside, 6"-O-beta-D-glucopyranosylipecoside, 6"-O-alpha-D-glucopyranosylipecoside and (4R)-4-hydroxyipecoside, were isolated. The structures of these glycosides w...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00418-6

    authors: Itoh A,Baba Y,Tanahashi T,Nagakura N

    更新日期:2002-01-01 00:00:00

  • Tetraoxygenated xanthones from the fruits of Garcinia cowa.

    abstract::Tetraoxygenated xanthones, cowaxanthones A-E, together with 10 previously reported tetraoxygenated xanthones, were isolated from the crude hexane extract of the fruits of Garcinia cowa. Cowaxanthone B has previously been reported as a synthetic xanthone. Their structures were elucidated by analysis of spectroscopic da...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.02.027

    authors: Panthong K,Pongcharoen W,Phongpaichit S,Taylor WC

    更新日期:2006-05-01 00:00:00

  • Sesquiterpenoids and diterpenoids from the Chilean liverwort Lepicolea ochroleuca.

    abstract::The ether extract of the Chilean liverwort Lepicolea ochroleuca yielded three sesquiterpenoids, ent-4 beta-Hydroxy-10 alpha-methoxyaromadendrane, ent-3 beta-Hydroxyspathulenol, and 1,10-Dioxotayloriane, as minor components. The major components were ledol and 13-epi-neoverrucosan-5 beta-ol, four other minor fusicoccan...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(99)00609-3

    authors: Liu HJ,Wu CL,Becker H,Zapp J

    更新日期:2000-04-01 00:00:00

  • An acylated cyanidin glycoside in the red-purple flowers of x Laeliocattleya cv mini purple.

    abstract::A new acylated anthocyanin was isolated from the red-purple flowers of x Laeliocattleya cv Mini Purple as one of the major anthocyanins. The structure of this pigment was determined to be cyanidin 3-O-[6-O-(malonyl)-beta-D-glucopyranoside]-7-O-[6-O-(trans-p- coumaryl)-beta-D-glucopyranoside]-3'-O-[6-O-[trans-4-O-[6-O-...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)89553-9

    authors: Tatsuzawa F,Saito N,Yokoi M,Shigihara A,Honda T

    更新日期:1994-11-01 00:00:00

  • The phytoalexins from cauliflower, caulilexins A, B and C: isolation, structure determination, syntheses and antifungal activity.

    abstract::Our continuous search for phytoalexins from crucifers led us to examine phytoalexin production in florets of cauliflower (Brassica oleracea var. botrytis) under abiotic (UV light) elicitation. Four known (isalexin, S-(-)-spirobrassinin, 1-methoxybrassitin, brassicanal C) and three new (caulilexins A-C) phytoalexins we...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.05.020

    authors: Pedras MS,Sarwar MG,Suchy M,Adio AM

    更新日期:2006-07-01 00:00:00

  • Purification and partial characterization of a Schizolobium parahyba chymotrypsin inhibitor.

    abstract::Schizolobium parahyba seed chymotrypsin inhibitor (SPC) is a protein with M(r) of 20,000 and four half-cystine residues and no free thiol group. SPC is stable at temperatures up to 75 degrees at pH 7 but gradually loses activity when kept at 95 degrees for 1 hr and total inactivation occurs after 5 hr. Amino acid anal...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(94)00921-f

    authors: Souza EM,Mizuta K,Sampaio MU,Sampaio CA

    更新日期:1995-06-01 00:00:00

  • Solar UV-B radiation modulates chemical defenses against Anticarsia gemmatalis larvae in leaves of field-grown soybean.

    abstract::Although it is well known that solar ultraviolet B (UV-B) radiation enhances plant defenses, there is less knowledge about traits that define insect resistance in field-grown soybean. Here we study the effects of solar UV-B radiation on: a) the induction of phenolic compounds and trypsin proteinase inhibitors (TPI) in...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.05.006

    authors: Dillon FM,Chludil HD,Zavala JA

    更新日期:2017-09-01 00:00:00

  • Lignan and megastigmane glycosides from Sauropus androgynus.

    abstract::A lignan diglycoside, (-)-isolariciresinol 3alpha-O-beta-apiofuranosyl-(1-->2)-O-beta-glucopyranoside, and a megastigmane glucoside, sauroposide, were isolated from the aerial part of Sauropus androgynus together with (+)-isolariciresinol 3alpha-O-beta-glucopyranoside, (-)-isolariciresinol 3alpha-O-beta-glucopyranosid...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(03)00219-x

    authors: Kanchanapoom T,Chumsri P,Kasai R,Otsuka H,Yamasaki K

    更新日期:2003-08-01 00:00:00

  • Tropane alkaloids from the stem bark of Erythroxylum bezerrae.

    abstract::Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis....

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2020.112458

    authors: Brito LSO,Pinto FDCL,de Filho MOM,Rocha DD,Mendoza MFM,Ayala AP,Bezerra BP,Loiola MIB,Canuto KM,Silveira ER,Pessoa ODL

    更新日期:2020-10-01 00:00:00

  • Friedolanostanes and xanthones from the twigs of Garcinia hombroniana.

    abstract::The twigs of Garcinia hombroniana yielded six compounds: two 17,14-friedolanostanes (garcihombronanes K-L, 1-2) and four xanthones (garcihombronones A-D, 3-6) together with 14 known compounds including four friedolanostanes, one lanostane, six xanthones, two benzoic acid derivatives and one biflavonoid. Their structur...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.08.020

    authors: Klaiklay S,Sukpondma Y,Rukachaisirikul V,Phongpaichit S

    更新日期:2013-01-01 00:00:00

  • Stereoselectivity of the demethylation of nicotine piperidine homologues by Nicotiana plumbaginifolia cell suspension cultures.

    abstract::The metabolism of (R,S)-N-methylanabasine and (R,S)-N-methylanatabine has been studied in a cell suspension culture of Nicotiana plumbaginifolia. Both substrates are effectively demethylated, anabasine or anatabine, respectively, accumulating in the medium. Similarly, there is strong stereoselectivity for the (R)-isom...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.07.012

    authors: Bartholomeusz TA,Molinié R,Roscher A,Felpin FX,Gillet F,Lebreton J,Mesnard F,Robins RJ

    更新日期:2005-08-01 00:00:00

  • ent-Labdane diterpenes from the aquatic plant Potamogeton pectinatus.

    abstract::Four new ent-labdane diterpenes were isolated from the freshwater aquatic plant Potamogeton pectinatus, together with two known furano-ent-labdanes. The new compounds were assigned the structures methyl-15,16-epoxy-12(R)-acetoxy- 8(17), 13(16),14-ent-labdatrien-19-oate,15,16-epoxy-12(R)-acetoxy-8(17), 13(16),14-ent-la...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2003.08.014

    authors: Waridel P,Wolfender JL,Lachavanne JB,Hostettmann K

    更新日期:2003-12-01 00:00:00

  • A-type proanthocyanidin antioxidant from Dioclea lasiophylla.

    abstract::The A-type proanthocyanidin, epigallocatechin-(2beta-->7,4beta-->8)-epicatechin, together with the known epicatechin, luteolin 3'beta-D-glucopyranoside, chrysoeriol 7beta-D-glucopyranoside and 2-methylpentan-2,4-diol, were isolated from leaves of Dioclea lasiophilla. The structures were established on the basis of the...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00297-1

    authors: Barreiros AL,David JP,de Queiroz LP,David JM

    更新日期:2000-12-01 00:00:00

  • Diversity of fatty acid composition of symbiotic dinoflagellates in corals: evidence for the transfer of host PUFAs to the symbionts.

    abstract::High diversity of fatty acid (FA) composition of endosymbiotic dinoflagellates of the Symbiodinium group (zooxanthellae) isolated from different cnidarian groups has been found. To explain this diversity, FA composition of the total lipids of pure symbiont fractions (SF) and host cell tissue fractions (HF) isolated fr...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.02.012

    authors: Imbs AB,Yakovleva IM,Dautova TN,Bui LH,Jones P

    更新日期:2014-05-01 00:00:00

  • Bromoperoxidase activity and vanadium level of the brown alga Ascophyllum nodosum.

    abstract::Vanadium-dependent peroxidase activity in extracts of Ascophyllum nodosum growing in the intertidal region close to Roscoff/France, and algal vanadium levels, followed approximately similar seasonal variation, as deduced from a study lasting from April 2005 to March 2006. High peroxidase (PO) activity was found in ext...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.09.004

    authors: Hartung J,Brücher O,Hach D,Schulz H,Vilter H,Ruick G

    更新日期:2008-11-01 00:00:00

  • Comparative phytochemical analysis of four Mexican Nymphaea species.

    abstract::Four Mexican Nymphaea species, N. ampla, N. pulchella, N. gracilis and N. elegans belonging to subgenera Brachyceras were analyzed. In this work two 5-glycosyl isoflavones, 7,3',4'-trihydroxy-5-O-beta-D-(2''-acetyl)-xylopyranosylisoflavone (1) and 7,3',4'-trihydroxy-5-O-alpha-L-rhamnopyranosylisoflavone (2), were isol...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.02.027

    authors: Marquina S,Bonilla-Barbosa J,Alvarez L

    更新日期:2005-04-01 00:00:00

  • Phytotoxicity and volatile constituents from leaves of Callicarpa japonica Thunb.

    abstract::The essential oil from the leaves of Callicarpa japonica was analyzed by GC-MS, and 84 compounds were identified. The main constituents of the essential oil were spathulenol (18.1%), germacrene B (13.0%), bicyclogermacrene (11.0%), globulol (3.3%), viridiflorol (2.6%), alpha-guaiene (2.3%), and gamma-elemene (2.0%). T...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00207-8

    authors: Kobaisy M,Tellez MR,Dayan FE,Duke SO

    更新日期:2002-09-01 00:00:00

  • Molecular cloning and characterization of an amidase from Arabidopsis thaliana capable of converting indole-3-acetamide into the plant growth hormone, indole-3-acetic acid.

    abstract::Acylamidohydrolases from higher plants have not been characterized or cloned so far. AtAMI1 is the first member of this enzyme family from a higher plant and was identified in the genome of Arabidopsis thaliana based on sequence homology with the catalytic-domain sequence of bacterial acylamidohydrolases, particularly...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00563-0

    authors: Pollmann S,Neu D,Weiler EW

    更新日期:2003-02-01 00:00:00

  • Steroidal saponins from the bulbs of Camassia cusickii.

    abstract::Six new steroidal saponins have been isolated from the fresh bulbs of Camassia cusickii. Their structures were determined by spectroscopic analysis and some chemical transformations to be (25R)-5 alpha-spirostan-3 beta,6 alpha-diol (chlorogenin) 6-O-beta-D-glucopyranoside, chlorogenin 6-O-beta-D-glucopyranosyl-(1----2...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(91)80098-l

    authors: Mimaki Y,Sashida Y,Kawashima K

    更新日期:1991-01-01 00:00:00