Review of implementation processes for integrated nutrition and psychosocial stimulation interventions.

abstract：:Obesity is a public health epidemic associated with a number of comorbidities, most notably type 2 diabetes and hypertension, as well as elevated all-cause mortality. The treatment for obesity and its associated comorbidities has most recently expanded into the field of bariatric endoscopy. This field bridges a gap be...

journal_title：Annals of the New York Academy of Sciences

authors： Hill C,Khashab MA,Kalloo AN,Kumbhari V

更新日期：2018-01-01 00:00:00

abstract：:Vitamin A deficiency has been shown to affect vision, reproduction, cellular differentiation, and maintenance of epithelial and skeletal tissues. Different vitamin A compounds, i.e., retinol and retinoic acid, vary in their ability to fulfill these biologic functions. Aside from vision, the exact molecular mechanisms ...

journal_title：Annals of the New York Academy of Sciences

authors： Navia JM,Harris SS

更新日期：1980-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) frequently develop and progress in settings in which sympathoadrenomedullary and gonadal hormone levels are changing, e.g., during pregnancy, postpartum period, menopause, estrogen administration. This paper addresses the view that adrenal and gonadal ho...

journal_title：Annals of the New York Academy of Sciences

authors： Wilder RL,Elenkov IJ

更新日期：1999-06-22 00:00:00

abstract：:Extension of mammalian health and life span has been achieved using various dietary interventions. We previously reported that restricting dietary methionine (MET) content extends life span only when growth hormone signaling is intact (no life span increase in GH deficiency or GH resistance). To understand the metabol...

journal_title：Annals of the New York Academy of Sciences

authors： Brown-Borg HM,Rakoczy S,Wonderlich JA,Borg KE,Rojanathammanee L

更新日期：2018-04-01 00:00:00

abstract：:Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder caused by antibodies directed against the voltage-gated calcium channels that provide the calcium ion flux that triggers acetylcholine release at the neuromuscular junction. To study the pathophysiology of LEMS and test candidate therapeutic strategies...

journal_title：Annals of the New York Academy of Sciences

authors： Meriney SD,Tarr TB,Ojala KS,Wu M,Li Y,Lacomis D,Garcia-Ocaña A,Liang M,Valdomir G,Wipf P

更新日期：2018-01-01 00:00:00

abstract：:Long-lived proteins undergo age-related postsynthetic modifications by glycation and advanced glycation end products (AGEs), which destabilize them by altering their conformation and charge. It was accidentally discovered that ornithine (orn) increased with age in acid hydrolyzates of human skin collagen and lens crys...

journal_title：Annals of the New York Academy of Sciences

authors： Sell DR,Monnier VM

更新日期：2005-06-01 00:00:00

abstract：:Intense stress can be detrimental for tissue homeostasis and accelerates aging. On the other hand, repeated mild stresses can have beneficial and even life-prolonging effects. Hypersecretion of glucocorticoids (GCs) represents the major hormonal response to stress. However, besides its life-sustaining role, GC excess ...

journal_title：Annals of the New York Academy of Sciences

authors： Kletsas D,Pratsinis H,Gioni V,Pilichos K,Yiacoumettis AM,Tsagarakis S

更新日期：2007-04-01 00:00:00

abstract：:The primary objective of this review is to suggest a major role of cytogenetic pathology in the genesis of both the neoplastic phenotype and the senescent phenotype of aging mammalian organisms. It is hypothesized that allelic variation at a number of genetic loci that have the potential to modulate various types of c...

journal_title：Annals of the New York Academy of Sciences

authors： Martin GM

更新日期：1991-01-01 00:00:00

abstract：:The authors present a multifactorial model for the development of acquired immunodeficiency syndrome (AIDS) in homosexual men. It is posited that there is no specific AIDS agent; rather, AIDS is conceptualized as the result of an interaction of the known or likely effects of repeated exposures to specific environment...

journal_title：Annals of the New York Academy of Sciences

authors： Sonnabend JA,Witkin SS,Purtilo DT

更新日期：1984-01-01 00:00:00

abstract：:The distinction between episodic and semantic memory has become very popular since it was first proposed by Tulving in 1972. So far, very few neuropsychological, psychophysical, and imaging studies have related to the mnemonic aspects of music, notably on the long-term memory features, and practically nothing is known...

journal_title：Annals of the New York Academy of Sciences

authors： Platel H

更新日期：2005-12-01 00:00:00

abstract：:Thromboembolic and infectious events were found to be major complications of long-term total artificial heart implantation in two patients. Similar complications have been reported in other patients, as well as in animal studies. The thromboembolic events and the infectious complications appear to be interrelated. On ...

journal_title：Annals of the New York Academy of Sciences

authors： Ward RA,Wellhausen SR,Dobbins JJ,Johnson GS,DeVries WC

更新日期：1987-01-01 00:00:00

abstract：:Soluble decoy receptor 3 (DcR3), a member of the tumor necrosis factor receptor superfamily, has recently been reported to increase osteoclast (OC) differentiation. Its impact on the skeleton was reinforced by a study on DcR3 transgenic mice showing a decreased bone mass through the elevation of OC number, providing s...

journal_title：Annals of the New York Academy of Sciences

authors： Brunetti G,Oranger A,Mori G,Centonze M,Colaianni G,Rizzi R,Liso V,Zallone A,Grano M,Colucci S

更新日期：2010-03-01 00:00:00

abstract：:The injury to vascular endothelium seen in severe bacterial infection may be mediated by neutrophil-derived enzymes. Neutrophil adhesion to endothelium, a prerequisite for this process, is mediated sequentially by the leukocyte adhesion molecules L-selectin and the beta 2 integrins, including CD11b/CD18. We have explo...

journal_title：Annals of the New York Academy of Sciences

authors： Finn A,Strobel S,Levin M,Klein N

更新日期：1994-05-28 00:00:00

abstract：:A few years after the first description of free-circulating DNA in plasma and serum, the detection of tumor-associated overexpressed mRNA in plasma was also reported. This observation has been confirmed and it seems to be clear that the presence of free-circulating RNA is a ubiquitous phenomenon. In this short review ...

journal_title：Annals of the New York Academy of Sciences

authors： Fleischhacker M

更新日期：2006-09-01 00:00:00

abstract：:Oxidative stress is a common response of epidermal cells to a variety of noxious stimuli such as ultraviolet (UV) radiation from solar light and proinflammatory cytokines from skin-infiltrating leukocytes. Here, we report that two types of plant-derived antioxidants, the phenylpropanoid glycoside verbascoside as well ...

journal_title：Annals of the New York Academy of Sciences

authors： Pastore S,Potapovich A,Kostyuk V,Mariani V,Lulli D,De Luca C,Korkina L

更新日期：2009-08-01 00:00:00

abstract：:N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from rat brain (alpha 1B-I and alpha 1B-II) were found to differ in four r...

journal_title：Annals of the New York Academy of Sciences

authors： Stea A,Dubel SJ,Snutch TP

更新日期：1999-04-30 00:00:00

abstract：:Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease characterized by the destruction of insulin-secreting pancreatic β cells. In humans with T1D and in nonobese diabetic (NOD) mice (a murine model for human T1D), autoreactive T cells cause β-cell destruction, as transfer or deletion of these cells induces or...

journal_title：Annals of the New York Academy of Sciences

authors： Padgett LE,Broniowska KA,Hansen PA,Corbett JA,Tse HM

更新日期：2013-04-01 00:00:00

abstract：:There is an urgent need for surrogate biomarkers in clinical diagnostics but also preclinical in toxicology of chemicals and efficacy testing of pharmaceuticals. On the background of the emerging fields of systems biology and theranostics, the importance of time scales and the synchronization of complex biological rea...

journal_title：Annals of the New York Academy of Sciences

authors： Schrattenholz A,Soskić V,Groebe K

更新日期：2010-06-01 00:00:00

abstract：:Primates have stimulated more interest than any other group as humans are ranked in this same mammalian order. Gustatory responses of human and nonhuman primates have already been compared for compounds such as monosaccharides, oligosaccharides, polyols, amino acids, dipeptides, proteins, dihydrochalcones, sulfamates,...

journal_title：Annals of the New York Academy of Sciences

authors： Glaser D,Tinti JM,Nofre C

更新日期：1998-11-30 00:00:00

abstract：:The fate of alpha-hemoglobin chains and the cause of membrane protein defects in thalassemic erythrocytes have been studied in: (1) human beta-thalassemia syndromes, (2) mouse beta-thalassemia, and (3) normal human erythrocytes loaded with purified alpha-hemoglobin chains. The similarity and differences observed in th...

journal_title：Annals of the New York Academy of Sciences

authors： Rouyer-Fessard P,Scott MD,Leroy-Viard K,Garel MC,Bachir D,Galacteros F,Beuzard Y

更新日期：1990-01-01 00:00:00

abstract：:Indirect evidence, including neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-neurotoxicity by nitric oxide synthase (NOS) inhibitors and resistance of transgenic animals deficient in NOS, is controversial. We have reviewed evidence in favor of oxidative stress during the development of MPTP...

journal_title：Annals of the New York Academy of Sciences

authors： Mohanakumar KP,Thomas B,Sharma SM,Muralikrishnan D,Chowdhury R,Chiueh CC

更新日期：2002-05-01 00:00:00

abstract：:The accepted dogma has been that a single long-term hematopoietic stem cell (LT-HSC) can reconstitute all components of the immune system. However, our single-cell transfer studies have shown that highly purified LT-HSCs selectively fail to reconstitute B-1a cells in otherwise fully reconstituted hosts (i.e., LT-HSCs ...

journal_title：Annals of the New York Academy of Sciences

authors： Ghosn EE,Yang Y

更新日期：2015-12-01 00:00:00

abstract：:Our earlier studies of translation have led us to a specific numeric coding of nucleotides (A = 0, C = 1, G = 2, and U = 3)--that is, a quaternary numeric system; to ordering of digrams and codons (read right to left: .yx and Z.yx) as ordinal numbers from 000 to 111; and to seek hypothetic transformation of mRNA to 20...

journal_title：Annals of the New York Academy of Sciences

authors： Damjanović ZM,Rakocević MM

更新日期：2005-06-01 00:00:00

abstract：:In epithelial and endothelial cell layers tight junctions form selective apicolateral paracellular barriers separating luminal and extracellular spaces from the underlying tissues. Within the tight junctions the tetraspan transmembrane proteins occludin, claudins, and tricellulin form anastomosing strands of protein c...

journal_title：Annals of the New York Academy of Sciences

authors： Dörfel MJ,Westphal JK,Huber O

更新日期：2009-05-01 00:00:00

abstract：:In the history of science, technical advances often precede periods of rapid accumulation of knowledge. Within the past three decades, discoveries that enabled the noninvasive measurement of the psychobiology of stress (in saliva) have added new dimensions to the study of health and human development. This widespread ...

journal_title：Annals of the New York Academy of Sciences

authors： Granger DA,Kivlighan KT,el-Sheikh M,Gordis EB,Stroud LR

更新日期：2007-03-01 00:00:00

abstract：:Considerable clinical and experimental evidence indicates that loss of vestibular function results in cognitive deficits, especially deficits in spatial memory. These studies demonstrate the importance of balance for the most fundamental of cognitive processes and suggest that information about head acceleration and o...

journal_title：Annals of the New York Academy of Sciences

authors： Smith PF,Brandt T,Strupp M,Darlington CL,Zheng Y

更新日期：2009-05-01 00:00:00

abstract：:Bisphosphonates are widely used in the management of metastatic disease to bone and in diseases of altered bone turnover. Recently, multiple-case series and retrospective studies have established a relationship between necrotic bone lesions localized to the jaw and the use of chronic bisphosphonate therapy. This condi...

journal_title：Annals of the New York Academy of Sciences

authors： Ruggiero SL

更新日期：2011-02-01 00:00:00

abstract：:Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). SRC occurs during the first 4 years of disease evolution in more than 75% of the cases, almost exclusively in patients with diffuse SSc. Other risk factors, including preceding corticosteroid therapy, have been associated...

journal_title：Annals of the New York Academy of Sciences

authors： Teixeira L,Mahr A,Berezné A,Noël LH,Guillevin L,Mouthon L

更新日期：2007-06-01 00:00:00

abstract：:Transcriptome analysis is a powerful tool to characterize changes in leukocyte gene expression patterns and reveal very early molecular abnormalities in tissue. Herein, we report on characterization of the very earliest abnormalities in the transcriptome of leukocytes from young "prepathologic" NOD and NON female mice...

journal_title：Annals of the New York Academy of Sciences

authors： Gerling IC,Ali C,Lenchik N

更新日期：2003-11-01 00:00:00

abstract：:Both hereditary and environmental factors influence the risk of cancer. Four risk categories, or oncodemes, can exist for a particular kind of cancer, depending upon the presence of neither, one, or both factors: (1) spontaneous, or background; (2) hereditary; (3) environmental; (4) interactive. In the second, mutatio...

journal_title：Annals of the New York Academy of Sciences

authors： Knudson AG

更新日期：1997-12-29 00:00:00