Transdermal applications of ethosomes - a detailed review.

Abstract:

:Skin, the largest organ of the body serves as a potential route of drug delivery for local and systemic effects. However, the outermost layer of skin, the stratum corneum (SC) acts as a tough barrier that prevents penetration of hydrophilic and high molecular weight drugs. Ethosomes are a novel phospholipid vesicular carrier containing high ethanol concentrations and offer improved skin permeability and efficient bioavailability due to their structure and composition. This article gives a review of ethosomes including their compositions, types, mechanism of drug delivery, stability, and safety behaviour. This article also provides a detailed overview of drug delivery applications of ethosomes in various diseases.

journal_name

J Liposome Res

authors

Nainwal N,Jawla S,Singh R,Saharan VA

doi

10.1080/08982104.2018.1517160

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

103-113

issue

2

eissn

0898-2104

issn

1532-2394

journal_volume

29

pub_type

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